Development of a physiologically based pharmacokinetic (PBPK) model for methyl iodide in rats, rabbits, and humans

Inhalation Toxicology

Volumn 21, Issue 6, 2009, Pages 552-582

  Sweeney, Lisa M ^a   Kirman, Christopher R ^b   Gannon, Shawn A ^c   Thrall, Karla D ^d   Gargas, Michael L ^a   Kinzell, John H ^e,f  

^a Sapphire Group   (United States)

^b Sapphire Group Inc   (United States)

^c DUPONT COMPANY   (United States)

^d PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^e ARYSTA LIFESCIENCE CORPORATION   (United States)

^f Xeris Pharmaceuticals Inc   (United States)

Author keywords

Glutathione; Iodide; Methyl iodide; Physiologically based pharmacokinetic(PBPK)modeling

Indexed keywords

GLUTATHIONE; METHYL BROMIDE; METHYL IODIDE;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; EXPERIMENTAL RABBIT; FEMALE; FETUS WASTAGE; HEART OUTPUT; HUMAN; HUMAN TISSUE; LUNG VENTILATION; MALE; NEUROTOXICITY; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; RISK ASSESSMENT;

ADIPOSE TISSUE; ADULT; AGED; ANIMALS; BRAIN; CHILD; FEMALE; HUMANS; HYDROCARBONS, IODINATED; INFANT; KIDNEY; MALE; MODELS, BIOLOGICAL; NASAL MUCOSA; PREGNANCY; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY PHYSIOLOGICAL PHENOMENA;

ANIMALIA; ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 70350587011     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370802601569     Document Type: Article

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