Three-Dimensional Mapping of Ozone-Induced Injury in the Nasal Airways of Monkeys Using Magnetic Resonance Imaging and Morphometric Techniques

Toxicologic Pathology

Volumn 35, Issue 1, 2007, Pages 27-40

  Carey, Stephan A ^a   Minard, Kevin R ^b   Trease, Lynn L ^b   Wagner, James G ^a   Garcia, Guilherme J M ^c   Ballinger, Carol A ^d   Kimbell, Julia S ^c   Plopper, Charles G ^e   Corley, Richard A ^b   Postlethwait, Edward M ^d   Harkema, Jack R ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

computational fluid dynamics; Magnetic resonance imaging; morphometry; nasal toxicology; ozone

Indexed keywords

OZONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGY; CONTROLLED STUDY; DIAGNOSTIC IMAGING; GEOMETRY; HISTOPATHOLOGY; INJURY SEVERITY; MICROSCOPY; MODEL; MONKEY; MORPHOMETRICS; NECROSIS; NONHUMAN; NOSE DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RHESUS MONKEY; RHINITIS; RISK;

ANIMALS; COMPUTATIONAL BIOLOGY; IMAGING, THREE-DIMENSIONAL; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MALE; NASAL CAVITY; NASAL MUCOSA; OXIDANTS, PHOTOCHEMICAL; OZONE; RHINITIS; TURBINATES;

ANIMALIA; MACACA MULATTA; PRIMATES;

EID: 33847312157     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230601072343     Document Type: Article

References (41)

1. Ballinger CA Cueto R Squadrito G Coffin JF Velsor LW Pryor WA Postlethwait EM Antioxidant-mediated augmentation of ozone-induced membrane oxidation Free Rad Biol Med 2005 38 515 26
2. Brain JD The uptake of inhaled gases by the nose Ann Otol Rhinol Laryngol 1970 79 529 39
3. Dahl AR Hadley WM Nasal cavity enzymes involved in xenobiotic metabolism: effects on the toxicity of inhalants Crit Rev Toxicol 1991 21 345 72
4. Dahl AR Hadley WM Hahn FF Benson JM McClellan RO Cytochrome P-450-dependent monooxygenases in olfactory epithelium of dogs: possible role in tumorigenicity Science 1982 216 57 9
5. Evans MJ Fanucchi MV Baker GL Van Winkle LS Pantle LM Nishio SJ Schelegle ES Gershwin LJ Miller LA Hyde DM Sannes PL Plopper CG Atypical development of the tracheal basement membrane zone of infant rhesus monkeys exposed to ozone and allergen Amer J Physiol Lung Cell Mol Physiol 2003 285 L931 9
6. Flanagan P Eccles R Spontaneous changes of unilateral nasal airflow in man. A re-examination of the ‘nasal cycle’ Acta Otolaryngol 1997 117 590 5
7. Gross EA Starr TB Randall HW Morgan KT Morphometric analysis of the primate nasal cavity Toxicologist 1987 7 193
8. Gross EA Swenberg JA Fields S Popp JA Comparative morphometry of the nasal cavity in rats and mice J Anat 1982 135 83 8
9. Harkema JR Comparative aspects of nasal airway anatomy: relevance to inhalation toxicology Toxicol Pathol 1991 19 321 36
10. Harkema JR Carey SA Wagner JG The nose revisited: a brief review of the comparative structure, function, and toxicologic pathology of the nasal epithelium Toxicol Pathol 2006 34 252 69
11. Harkema JR Plopper CG Hyde DM St George JA Regional differences in quantities of histochemically detectable mucosubstances in nasal, paranasal, and nasopharyngeal epithelium of the bonnet monkey J Histochem Cytochem 1987a 35 279 86
12. Harkema JR Plopper CG Hyde DM St George JA Dungworth DL Effects of an ambient level of ozone on primate nasal epithelial mucosubstances. Quantitative histochemistry Amer J Pathol 1987b 127 90 6
13. Harkema JR Plopper CG Hyde DM St George JA Wilson DW Dungworth DL Response of the macaque nasal epithelium to ambient levels of ozone. A morphologic and morphometric study of the transitional and respiratory epithelium Amer J Pathol 1987c 128 29 44
14. Harkema JR Plopper CG Hyde DM Wilson DW St George JA Wong VJ Nonolfactory surface epithelium of the nasal cavity of the bonnet monkey: a morphologic and morphometric study of the transitional and respiratory epithelium Amer J Anat 1987d 180 266 79
15. Harris AJ Squires SM Hockings PD Campbell SP Greenhill RW Mould A Reid DG Determination of surface areas, volumes, and lengths of cynomolgus monkey nasal cavities by ex vivo magnetic resonance imaging J Aero Med 2003 16 99 105
16. Hinners RG Burkart JK Punte CL Animal inhalation exposure chambers Arch Environ Health 1968 16 194 206
17. Housley DG Mudway I Kelly FJ Eccles R Richards RJ Depletion of urate in human nasal lavage following in vitro ozone exposure Int J Biochem Cell Biol 1995 27 1153 9
18. Hyde DM Harkema JR Tyler NK Plopper CG Design-based sampling and quantitation of the respiratory airways Toxicol Pathol 2006 34 286 95
19. Hyde DM Magliano DJ Plopper CG Morphometric assessment of pulmonary toxicity in the rodent lung Toxicol Pathol 1991 19 428 46
20. Hyde DM Plopper C St George JA Harkema JR Schraufnagel DE Morphometric cell biology of airspace epithelium Electron Microscopy of the Lung 1990 New York Marcel Dekker 1 120
21. Kepler GM Joyner DR Fleishman A Richardson RB Gross EA Morgan KT Godo MN Kimbell JS Method for obtaining accurate geometrical coordinates on nasal airways for computer dosimetry modeling and lesion mapping Inhal Toxicol 1995 7 1207 24
22. Kepler GM Richardson RB Morgan KT Kimbell JS Computer simulation of inspiratory nasal airflow and inhaled gas uptake in a rhesus monkey Toxicol Appl Pharmacol 1998 150 1 11
23. Kimbell JS Nasal dosimetry of inhaled gases and particles: where do inhaled agents go in the nose? Toxicol Pathol 2006 34 270 3
24. Larson SD Plopper CG Baker G Tarkington BK Decile KC Pinkerton K Mansoor JK Hyde DM Schelegle ES Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide American J Physiol Lung Cell Molec Physiol 2004 287 L286 95
25. Lippmann M Deposition and clearance of inhaled particles in the human nose Ann Otol Rhinol Laryngol 1970 79 519 28
26. Menache MG Hanna LM Gross EA Lou SR Zinreich SJ Leopold DA Jarabek AM Miller FJ Upper respiratory tract surface areas and volumes of laboratory animals and humans: considerations for dosimetry models J Toxicol Environ Health 1997 50 475 506
27. Mery S Gross EA Joyner DR Godo M Morgan KT Nasal diagrams: a tool for recording the distribution of nasal lesions in rats and mice Toxicol Pathol 1994 22 353 72
28. Minard KR Einstein DR Jacob RE Kabilan S Kuprat AP Timchalk CA Trease LL Corley RA Application of magnetic resonance (MR) imaging for the development and validation of computational fluid dynamic (CFD) models of the rat respiratory system Inhal Toxicol 2006 18 787 94
29. Morgan KT Monticello TM Airflow, gas deposition, and lesion distribution in the nasal passages Environ Health Perspect 1990 85 209 18
30. Morgan KT Frank R Brain JD Proctor DF Reid LM Uptake of pollutant gases by the respiratory system Respiratory Defense Mechanisms 1977 New York Marcel Dekker
31. Mudway IS Kelly FJ Modeling the interactions of ozone with pulmonary epithelial lining fluid antioxidants Toxicol Appl Pharmacol 1998 148 91 100
32. Plopper CG Chu FP Haselton CJ Peake J Wu J Pinkerton KE Dose-dependent tolerance to ozone. I. Tracheobronchial epithelial reorganization in rats after 20 months’ exposure Amer J Pathol 1994 144 404 20
33. Proctor D Anderson I The Nose: Upper Airway Physiology and the Atmospheric Environment 1982 Amsterdam Elsevier Biomedical Press
34. Robinson DA Foster JR Nash JA Reed CJ Three-dimensional mapping of the lesions induced by beta-beta’-iminodiproprionitrile, methyl iodide and methyl methacrylate in the rat nasal cavity Toxicol Pathol 2003 31 340 7
35. Schreider JP Barrow CS Comparative anatomy and function of the nasal passages Toxicology of the Nasal Passages 1986 New York Hemisphere 1 25
36. Sorokin SP Weiss L The respiratory system Cell and Tissue Biology: A Textbook of Histology 1988 Baltimore Urban & Schwarzenberg 751 814
37. Tyler WS Dungworth DL Plopper C Hyde DM Tyler NK Structural evaluation of the respiratory system Fundam Appl Toxicol 1985 5 405 22
38. Velsor LW Postlethwait EM NO2-induced generation of extra-cellular reactive oxygen is mediated by epithelial lining layer antioxidants Amer J Physiol 1997 273 L1265 75
39. Wiethoff AJ Harkema JR Koretsky AP Brown WE Identification of mucosal injury in the murine nasal airways by magnetic resonance imaging: site-specific lesions induced by 3-methylindole Toxicol Appl Pharmacol 2001 175 68 75
40. Yeh HC Brinker RM Harkema JR Muggenburg BA A comparative analysis of primate nasal airways using magnetic resonance imaging and nasal casts J Aerosol Med 1997 10 319 29
41. Young JT Histopathologic examination of the rat nasal cavity Fundam Appl Toxicol 1981 1 309 12