메뉴 건너뛰기




Volumn 79, Issue 2, 2004, Pages 394-403

Ethyl acrylate risk assessment with a hybrid computational fluid dynamics and physiologically based nasal dosimetry model

Author keywords

Acrylic acid; Ethyl acrylate; Glutathione; Olfactory epithelium; Reference concentration

Indexed keywords

ACRYLIC ACID; ACRYLIC ACID ETHYL ESTER; GLUTATHIONE;

EID: 2942750427     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh116     Document Type: Article
Times cited : (13)

References (33)
  • 1
    • 0030056460 scopus 로고    scopus 로고
    • Investigation of the impact of pharmacokinetic variability and uncertainty on risks predicted with a pharmacokinetic model for chloroform
    • Allen, B. C., Covington, T. R., and Clewell, H. J. (1996). Investigation of the impact of pharmacokinetic variability and uncertainty on risks predicted with a pharmacokinetic model for chloroform. Toxicology 111, 289-303.
    • (1996) Toxicology , vol.111 , pp. 289-303
    • Allen, B.C.1    Covington, T.R.2    Clewell, H.J.3
  • 2
    • 0033795067 scopus 로고    scopus 로고
    • Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: An example with acrylic acid
    • Andersen, M., Sarangapani, R., Gentry, R., Clewell, H., Covington, T., and Frederick, C. B. (2000). Application of a hybrid CFD-PBPK nasal dosimetry model in an inhalation risk assessment: An example with acrylic acid. Toxicol. Sci. 57, 312-325.
    • (2000) Toxicol. Sci. , vol.57 , pp. 312-325
    • Andersen, M.1    Sarangapani, R.2    Gentry, R.3    Clewell, H.4    Covington, T.5    Frederick, C.B.6
  • 3
    • 0027499860 scopus 로고
    • The characterization of glutathione S-transferases from rat olfactory epithelium
    • Banger, K. K., Lock, E. A., and Reed, C. J. (1993). The characterization of glutathione S-transferases from rat olfactory epithelium. Biochem. J. 290 (Pt. 1), 199-204.
    • (1993) Biochem. J. , vol.290 , Issue.PART 1 , pp. 199-204
    • Banger, K.K.1    Lock, E.A.2    Reed, C.J.3
  • 4
    • 0030582430 scopus 로고    scopus 로고
    • Regulation of rat olfactory glutathione S-transferase expression. Investigation of sex differences, induction, and ontogenesis
    • Banger, K. K., Lock, E. A., and Reed, C. J. (1996). Regulation of rat olfactory glutathione S-transferase expression. Investigation of sex differences, induction, and ontogenesis. Biochem. Pharmacol. 52, 801-808.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 801-808
    • Banger, K.K.1    Lock, E.A.2    Reed, C.J.3
  • 5
    • 0029054777 scopus 로고
    • Acrylic acid oxidation and tissue-to-blood partition coefficients in rat tissues
    • Black, K. A., and Finch, L. (1995). Acrylic acid oxidation and tissue-to-blood partition coefficients in rat tissues. Toxicol. Lett. 78, 73-78.
    • (1995) Toxicol. Lett. , vol.78 , pp. 73-78
    • Black, K.A.1    Finch, L.2
  • 6
    • 0023280283 scopus 로고
    • Biochemical quantitation and histochemical localization of carboxylesterase in the nasal passages of the Fischer-344 rat and B6C3F1 mouse
    • Bogdanffy, M. S., Randall, H. W., and Morgan, K. T. (1987). Biochemical quantitation and histochemical localization of carboxylesterase in the nasal passages of the Fischer-344 rat and B6C3F1 mouse. Toxicol. Appl. Pharmacol. 88, 183-194.
    • (1987) Toxicol. Appl. Pharmacol. , vol.88 , pp. 183-194
    • Bogdanffy, M.S.1    Randall, H.W.2    Morgan, K.T.3
  • 7
    • 0032429050 scopus 로고    scopus 로고
    • Analysis of vinyl acetate metabolism in rat and human nasal tissues by an in vitro gas uptake technique
    • Bogdanffy, M. S., Sarangapani, R., Kimbell, J. S., Frame, S. R., and Plowchalk, D. R. (1998). Analysis of vinyl acetate metabolism in rat and human nasal tissues by an in vitro gas uptake technique. Toxicol. Sci. 46, 235-246
    • (1998) Toxicol. Sci. , vol.46 , pp. 235-246
    • Bogdanffy, M.S.1    Sarangapani, R.2    Kimbell, J.S.3    Frame, S.R.4    Plowchalk, D.R.5
  • 9
    • 0031837429 scopus 로고    scopus 로고
    • A CFD-PBPK hybrid model for simulating gas and vapor uptake in the rat nose
    • Bush, M. L., Frederick, C. B., Kimbell, J. S., and Ultman, J. S. (1998). A CFD-PBPK hybrid model for simulating gas and vapor uptake in the rat nose. Toxicol. Appl. Pharmacol. 150, 33-45.
    • (1998) Toxicol. Appl. Pharmacol. , vol.150 , pp. 33-45
    • Bush, M.L.1    Frederick, C.B.2    Kimbell, J.S.3    Ultman, J.S.4
  • 10
    • 0023568352 scopus 로고
    • Oronasal distribution of ventilation during exercise in normal subjects and patients with asthma and rhinitis
    • Chadha, T. S., Birch, S., and Sackner, M. A. (1987). Oronasal distribution of ventilation during exercise in normal subjects and patients with asthma and rhinitis. Chest 92, 1037-1041
    • (1987) Chest , vol.92 , pp. 1037-1041
    • Chadha, T.S.1    Birch, S.2    Sackner, M.A.3
  • 11
    • 0031864744 scopus 로고    scopus 로고
    • The role of glutathione S-transferase and cytochrome P450-dependent metabolism in the olfactory toxicity of methyl iodide in the rat
    • Chamberlain, M. P., Lock, E. A., Gaskell, B. A., and Reed, C. H. (1998). The role of glutathione S-transferase and cytochrome P450-dependent metabolism in the olfactory toxicity of methyl iodide in the rat. Arch. Toxicol. 72, 420-428.
    • (1998) Arch. Toxicol. , vol.72 , pp. 420-428
    • Chamberlain, M.P.1    Lock, E.A.2    Gaskell, B.A.3    Reed, C.H.4
  • 12
    • 0031831694 scopus 로고    scopus 로고
    • Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro
    • Custodio, J. B., Palmeira, C. M., Moreno, A. J., and Wallace, K. B. (1998). Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro. Toxicol. Sci. 43, 19-27.
    • (1998) Toxicol. Sci. , vol.43 , pp. 19-27
    • Custodio, J.B.1    Palmeira, C.M.2    Moreno, A.J.3    Wallace, K.B.4
  • 13
    • 0031737679 scopus 로고    scopus 로고
    • Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper airways
    • Frederick, C. B., Bush, M. L., Lomax, L. G., Black, K. A., Finch, L., Kimbell, J. S., Morgan, K. T., Subramaniam, R. P., Morris, J. B., and Ultman, J. S. (1998). Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper airways. Toxicol. Appl. Pharmacol. 152, 211-231.
    • (1998) Toxicol. Appl. Pharmacol. , vol.152 , pp. 211-231
    • Frederick, C.B.1    Bush, M.L.2    Lomax, L.G.3    Black, K.A.4    Finch, L.5    Kimbell, J.S.6    Morgan, K.T.7    Subramaniam, R.P.8    Morris, J.B.9    Ultman, J.S.10
  • 15
    • 0026658925 scopus 로고
    • A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment
    • Frederick, C. B., Potter, D. W., Chang-Mateu, M. I., and Andersen, M. E. (1992). A physiologically based pharmacokinetic and pharmacodynamic model to describe the oral dosing of rats with ethyl acrylate and its implications for risk assessment. Toxicol. Appl. Pharmacol. 114, 246-260.
    • (1992) Toxicol. Appl. Pharmacol. , vol.114 , pp. 246-260
    • Frederick, C.B.1    Potter, D.W.2    Chang-Mateu, M.I.3    Andersen, M.E.4
  • 16
    • 0035029170 scopus 로고    scopus 로고
    • Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice
    • Haouzi, D., Lekehal, M., Tinel, M., Vadrot, N., Caussanel, L., Letteron, P., Moreau, A., Feldmann, G., Fau, D., and Pessayre D. (2001). Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice. Hepatology 33, 1181-1188.
    • (2001) Hepatology , vol.33 , pp. 1181-1188
    • Haouzi, D.1    Lekehal, M.2    Tinel, M.3    Vadrot, N.4    Caussanel, L.5    Letteron, P.6    Moreau, A.7    Feldmann, G.8    Fau, D.9    Pessayre, D.10
  • 17
    • 0030666294 scopus 로고    scopus 로고
    • Acrylic acid: Two-generation reproduction toxicity study in Wistar rats with continuous administration in the drinking water
    • Hellwig, J., Gembardt, C., and Murphy, S. R. (1997). Acrylic acid: Two-generation reproduction toxicity study in Wistar rats with continuous administration in the drinking water. Food Chem. Toxicol. 35, 859-868.
    • (1997) Food Chem. Toxicol. , vol.35 , pp. 859-868
    • Hellwig, J.1    Gembardt, C.2    Murphy, S.R.3
  • 18
    • 0036083422 scopus 로고    scopus 로고
    • Alcohol and mitochondria: A dysfunctional relationship
    • Hoek, J. B., Cahill, A., and Pastorino, J. G. (2002). Alcohol and mitochondria: A dysfunctional relationship. Gastroenterology 122, 2049-2063.
    • (2002) Gastroenterology , vol.122 , pp. 2049-2063
    • Hoek, J.B.1    Cahill, A.2    Pastorino, J.G.3
  • 19
    • 0034894807 scopus 로고    scopus 로고
    • A physiologically based pharmacokinetic model for methyl tert-butyl ether in humans: Implementing sensitivity and variability analyses
    • Licata, A. C., Dekant, W., Smith, C. E., and Borghoff, S. J. (2001). A physiologically based pharmacokinetic model for methyl tert-butyl ether in humans: Implementing sensitivity and variability analyses. Toxicol. Sci. 62, 191-204.
    • (2001) Toxicol. Sci. , vol.62 , pp. 191-204
    • Licata, A.C.1    Dekant, W.2    Smith, C.E.3    Borghoff, S.J.4
  • 20
    • 0000278639 scopus 로고
    • Regional histopathology of the mouse nasal cavity following two weeks of exposure to acrylic acid for either 6 or 22 hours per day
    • Lomax, L. G., Brown, D. W., and Frederick, C. B. (1994). Regional histopathology of the mouse nasal cavity following two weeks of exposure to acrylic acid for either 6 or 22 hours per day. Inhal. Toxicol. 6 (Suppl.), 445-449.
    • (1994) Inhal. Toxicol. , vol.6 , Issue.SUPPL. , pp. 445-449
    • Lomax, L.G.1    Brown, D.W.2    Frederick, C.B.3
  • 21
    • 0035857294 scopus 로고    scopus 로고
    • Methyl methacrylate toxicity in rat nasal epithelium: Studies of the mechanism of action and comparisons between species
    • Mainwaring, G., Foster, J. R., Lund, V., and Green, T. (2001). Methyl methacrylate toxicity in rat nasal epithelium: Studies of the mechanism of action and comparisons between species. Toxicology 158, 109-118.
    • (2001) Toxicology , vol.158 , pp. 109-118
    • Mainwaring, G.1    Foster, J.R.2    Lund, V.3    Green, T.4
  • 24
    • 12644304927 scopus 로고
    • National Toxicology Program Report No. 259. NIH Publication Number 87-2515
    • National Toxicology Program (1986). Toxicology and carcinogenesis studies of ethyl acrylate. Report No. 259. NIH Publication Number 87-2515.
    • (1986) Toxicology and Carcinogenesis Studies of Ethyl Acrylate
  • 25
    • 0038032435 scopus 로고    scopus 로고
    • National Toxicology Program Tenth Edition; U.S. Department of Health and Human Services, Public Health Service, December 2002
    • National Toxicology Program (2002). Report on Carcinogens, Tenth Edition; U.S. Department of Health and Human Services, Public Health Service, December 2002.
    • (2002) Report on Carcinogens
  • 26
    • 0027164292 scopus 로고
    • Apparent rates of glutathione turnover in rat tissues
    • Potter, D. W., and Tran, T. B. (1993). Apparent rates of glutathione turnover in rat tissues. Toxicol. Appl. Pharmacol. 120, 186-192.
    • (1993) Toxicol. Appl. Pharmacol. , vol.120 , pp. 186-192
    • Potter, D.W.1    Tran, T.B.2
  • 28
    • 0037253723 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile desposition in humans
    • Sweeney, L. M., Gargas, M. L., Strothor, D. E., Kedderis, G. L. (2003). Physiologically based pharmacokinetic model parameter estimation and sensitivity and variability analyses for acrylonitrile desposition in humans. Toxicol. Sci. 71, 27-40.
    • (2003) Toxicol. Sci. , vol.71 , pp. 27-40
    • Sweeney, L.M.1    Gargas, M.L.2    Strothor, D.E.3    Kedderis, G.L.4
  • 30
    • 0003536223 scopus 로고
    • Methods for derivation of inhalation reference concentrations and application of inhalation dosimetry
    • U.S. Environmental Protection Agency (EPA) Office of Research and Development, Washington, DC. EPA/600/8-90/066F
    • U.S. Environmental Protection Agency (EPA) (1994). Methods for derivation of inhalation reference concentrations and application of inhalation dosimetry. Office of Research and Development, Washington, DC. EPA/600/8-90/066F.
    • (1994)
  • 32
    • 0025601611 scopus 로고
    • Effects of inhaled acrylic acid derivatives in rats
    • Vodicka, P., Gut, I., and Frantik, E. (1990). Effects of inhaled acrylic acid derivatives in rats. Toxicology 65, 209-221.
    • (1990) Toxicology , vol.65 , pp. 209-221
    • Vodicka, P.1    Gut, I.2    Frantik, E.3
  • 33
    • 0029588563 scopus 로고
    • Physiologically based pharmacokinetic models applicable to organogenesis: Extrapolation between species and potential use in prenatal toxicity risk assessments
    • Welsch, F., Blumenthal, G. M., and Conolly, R. B. (1995). Physiologically based pharmacokinetic models applicable to organogenesis: Extrapolation between species and potential use in prenatal toxicity risk assessments. Toxicol. Lett. 82-83, 539-547.
    • (1995) Toxicol. Lett. , vol.82-83 , pp. 539-547
    • Welsch, F.1    Blumenthal, G.M.2    Conolly, R.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.