Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease

Journal of Clinical Investigation

Volumn 119, Issue 3, 2009, Pages 636-649

  Borchers, Michael T ^a   Wesselkamper, Scott C ^a   Curull, Victor ^b,c,d   Ramirez Sarmiento, Alba ^b,c   Sánchez Font, Albert ^b,c   Garcia Aymerich, Judith ^b   Coronell, Carlos ^b   Lloreta, Josep ^c,e   Agusti, Alvar G ^f,g   Gea, Joaquim ^c,e,f   Howington, John A ^a   Reed, Michael F ^a   Starnes, Sandra L ^a   Harris, Nathaniel L ^a   Vitucci, Mark ^a   Eppert, Bryan L ^a   Motz, Gregory T ^a   Fogel, Kevin ^a   McGraw, Dennis W ^a   Tichelaar, Jay W ^h   Orozco Levi, Mauricio ^b,c,e,f   more..

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^e UNIVERSITAT POMPEU FABRA   (Spain)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

^g HOSPITAL UNIVERSITARIO SON ESPASES   (Spain)

^h WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CIGARETTE SMOKE; GELATINASE A; GELATINASE B; HLA A ANTIGEN; LIGAND; NATURAL KILLER CELL RECEPTOR NKG2D; PROTEIN RETINOIC ACID EARLY TRANSCRIPT 1; UNCLASSIFIED DRUG; KLRK1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; RAET1A PROTEIN, MOUSE;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; CYTOTOXICITY; EMPHYSEMA; EPITHELIUM CELL; FEMALE; GENETIC MODEL; HUMAN; HUMAN TISSUE; LUNG ALVEOLUS EPITHELIUM; LUNG DISEASE; LUNG FUNCTION; LUNG PARENCHYMA; MALE; MOUSE; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPPRESSOR CELL; T LYMPHOCYTE; TRANSGENIC MOUSE; ANIMAL; CD8+ T LYMPHOCYTE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; LUNG; LYMPHOCYTE ACTIVATION; PATHOPHYSIOLOGY; RESPIRATORY TRACT MUCOSA; SMOKE; SMOKING;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; EMPHYSEMA; GENE EXPRESSION REGULATION; KILLER CELLS, NATURAL; LUNG; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SMOKE; SMOKING;

EID: 65649102628     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI34462     Document Type: Article

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