Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines

American Journal of Respiratory Cell and Molecular Biology

Volumn 42, Issue 3, 2010, Pages 304-311

  Moriyama, Chinatsu ^a   Betsuyaku, Tomoko ^a   Ito, Yoko ^a   Hamamura, Ichiro ^b   Hata, Junko ^b   Takahashi, Hiroshi ^b   Nasuhara, Yasuyuki ^a   Nishimura, Masaharu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b TEIJIN PHARMA LIMITED   (Japan)

Author keywords

Age; Bronchiolar epithelium; Chemokine; Neutrophil; Smoking

Indexed keywords

ANTIOXIDANT; CIGARETTE SMOKE; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; DETOXIFICATION; DISEASE PREDISPOSITION; GENE EXPRESSION; LASER CAPTURE MICRODISSECTION; LUNG; LUNG LAVAGE; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; SMOKING; UPREGULATION;

AGING; ANIMALS; ANTIOXIDANTS; BRONCHIOLES; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES; CHEMOTAXIS; DISEASE SUSCEPTIBILITY; EPITHELIUM; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KINETICS; MALE; MICE; MICE, INBRED C57BL; NEUTROPHILS; NF-KAPPA B; PEROXIDASE; RNA, MESSENGER; SMOKING;

MUS;

EID: 77249094660     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0025OC     Document Type: Article

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