Elastin fragments drive disease progression in a murine model of emphysema

Journal of Clinical Investigation

Volumn 116, Issue 3, 2006, Pages 753-759

  Houghton, A McGarry ^a   Quintero, Pablo A ^a   Perkins, David L ^a   Kobayashi, Dale K ^b   Kelley, Diane G ^b   Marconcini, Luiz A ^a   Mecham, Robert P ^b   Senior, Robert M ^b   Shapiro, Steven D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTACTIC FACTOR; CIGARETTE SMOKE; ELASTASE; ELASTIN; MACROPHAGE ELASTASE; MONOCLONAL ANTIBODY; PANCREATIC ELASTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMOTAXIS; DISEASE COURSE; EMPHYSEMA; ENZYME DEFICIENCY; FRACTIONATION; IN VITRO STUDY; IN VIVO STUDY; LUNG LAVAGE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMOKE; SWINE; WILD TYPE;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ELASTIN; EMPHYSEMA; MACROPHAGES, ALVEOLAR; MATRIX METALLOPROTEINASE 12; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; PEPTIDE FRAGMENTS; PULMONARY ALVEOLI; SMOKING;

EID: 33644643244     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI25617     Document Type: Article

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