메뉴 건너뛰기




Volumn 20, Issue 8, 2012, Pages 633-647

Revolutionizing drug delivery through biodegradable multilayered particles

Author keywords

Degradation; Multilayers; Poly(lactic acid); Poly(lactide co glycolide); Polymeric materials; Solvent evaporation

Indexed keywords

MICROSPHERE; NANOPARTICLE; POLYMER;

EID: 84864624329     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2012.702772     Document Type: Review
Times cited : (15)

References (95)
  • 1
    • 77956621320 scopus 로고    scopus 로고
    • Layer-by-layer-assembled capsules and films for therapeutic delivery
    • Becker AL, Johnston AP, Caruso F. (2010). Layer-by-layer-assembled capsules and films for therapeutic delivery. Small, 6, 1836-1852.
    • (2010) Small , vol.6 , pp. 1836-1852
    • Becker, A.L.1    Johnston, A.P.2    Caruso, F.3
  • 2
    • 4344672815 scopus 로고    scopus 로고
    • Three-month, zero-order piroxicam release from monodispersed double-walled microspheres of controlled shell thickness
    • Berkland C, Cox A, Kim K, Pack DW. (2004a). Three-month, zero-order piroxicam release from monodispersed double-walled microspheres of controlled shell thickness. J Biomed Mater Res A, 70, 576-584.
    • (2004) J. Biomed. Mater Res A , vol.70 , pp. 576-584
    • Berkland, C.1    Cox, A.2    Kim, K.3    Pack, D.W.4
  • 3
    • 0038537239 scopus 로고    scopus 로고
    • PLG microsphere size controls drug release rate through several competing factors
    • Berkland C, Kim K, Pack DW. (2003). PLG microsphere size controls drug release rate through several competing factors. Pharm Res, 20, 1055-1062.
    • (2003) Pharm. Res. , vol.20 , pp. 1055-1062
    • Berkland, C.1    Kim, K.2    Pack, D.W.3
  • 4
    • 0035907177 scopus 로고    scopus 로고
    • Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions
    • Berkland C, Kim K, Pack DW. (2001). Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions. J Control Release, 73, 59-74.
    • (2001) J. Control Release , vol.73 , pp. 59-74
    • Berkland, C.1    Kim, K.2    Pack, D.W.3
  • 5
    • 0037130249 scopus 로고    scopus 로고
    • Precise control of PLG microsphere size provides enhanced control of drug release rate
    • Berkland C, King M, Cox A, Kim K, Pack DW. (2002). Precise control of PLG microsphere size provides enhanced control of drug release rate. J Control Release, 82, 137-147.
    • (2002) J. Control Release , vol.82 , pp. 137-147
    • Berkland, C.1    King, M.2    Cox, A.3    Kim, K.4    Pack, D.W.5
  • 6
    • 1842473842 scopus 로고    scopus 로고
    • Uniform doublewalled polymer microspheres of controllable shell thickness
    • Berkland C, Pollauf E, Pack DW, Kim K. (2004b). Uniform doublewalled polymer microspheres of controllable shell thickness. J Control Release, 96, 101-111.
    • (2004) J. Control Release , vol.96 , pp. 101-111
    • Berkland, C.1    Pollauf, E.2    Pack, D.W.3    Kim, K.4
  • 7
    • 14844317382 scopus 로고    scopus 로고
    • Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles
    • Bilati U, Allémann E, Doelker E. (2005). Strategic approaches for overcoming peptide and protein instability within biodegradable nano- and microparticles. Eur J Pharm Biopharm, 59, 375-388.
    • (2005) Eur. J. Pharm. Biopharm. , vol.59 , pp. 375-388
    • Bilati, U.1    Allémann, E.2    Doelker, E.3
  • 8
    • 0028837083 scopus 로고
    • Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug-delivery
    • Brannon-Peppas L. (1995). Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug-delivery. Int J Pharm, 116, 1-9.
    • (1995) Int. J. Pharm. , vol.116 , pp. 1-9
    • Brannon-Peppas, L.1
  • 9
    • 0036320242 scopus 로고    scopus 로고
    • Why degradable polymers undergo surface erosion or bulk erosion
    • von Burkersroda F, Schedl L, Göpferich A. (2002). Why degradable polymers undergo surface erosion or bulk erosion. Biomaterials, 23, 4221-4231.
    • (2002) Biomaterials , vol.23 , pp. 4221-4231
    • Von Burkersroda, F.1    Schedl, L.2    Göpferich, A.3
  • 10
    • 39749095846 scopus 로고    scopus 로고
    • Controlled degradation of multilayered poly(lactide-co-glycolide) films using electron beam irradiation
    • Chia NK, Venkatraman SS, Boey FY, Cadart S, Loo JS. (2008). Controlled degradation of multilayered poly(lactide-co-glycolide) films using electron beam irradiation. J Biomed ater Res A, 84, 980-987.
    • (2008) J. Biomed. ater Res. A. , vol.84 , pp. 980-987
    • Chia, N.K.1    Venkatraman, S.S.2    Boey, F.Y.3    Cadart, S.4    Loo, J.S.5
  • 11
    • 77957018566 scopus 로고    scopus 로고
    • Fabrication of core-shell microcapsules using PLGA and alginate for dual growth factor delivery system
    • Choi DH, Park CH, Kim IH, Chun HJ, Park K, Han DK. (2010). Fabrication of core-shell microcapsules using PLGA and alginate for dual growth factor delivery system. J Control Release, 147, 193-201.
    • (2010) J. Control Release , vol.147 , pp. 193-201
    • Choi, D.H.1    Park, C.H.2    Kim, I.H.3    Chun, H.J.4    Park, K.5    Han, D.K.6
  • 12
    • 79952844292 scopus 로고    scopus 로고
    • Stimuli-responsive LbL capsules and nanoshells for drug delivery
    • Delcea M, Möhwald H, Skirtach AG. (2011). Stimuli-responsive LbL capsules and nanoshells for drug delivery. Adv Drug Deliv Rev, 63, 730-747.
    • (2011) Adv. Drug. Deliv. Rev. , vol.63 , pp. 730-747
    • Delcea, M.1    Möhwald, H.2    Skirtach, A.G.3
  • 14
    • 0036231029 scopus 로고    scopus 로고
    • PLGA-based microparticles: Elucidation of mechanisms and a new, simple mathematical model quantifying drug release
    • Faisant N, Siepmann J, Benoit JP. (2002). PLGA-based microparticles: Elucidation of mechanisms and a new, simple mathematical model quantifying drug release. Eur J Pharm Sci, 15, 355-366.
    • (2002) Eur. J. Pharm. Sci. , vol.15 , pp. 355-366
    • Faisant, N.1    Siepmann, J.2    Benoit, J.P.3
  • 15
    • 4444246813 scopus 로고    scopus 로고
    • Polymer microspheres for controlled drug release
    • Freiberg S, Zhu XX. (2004). Polymer microspheres for controlled drug release. Int J Pharm, 282, 1-18.
    • (2004) Int. J. Pharm. , vol.282 , pp. 1-18
    • Freiberg, S.1    Zhu, X.X.2
  • 16
    • 11844259383 scopus 로고    scopus 로고
    • Microencapsulation by solvent extraction/evaporation: Reviewing the state of the art of microsphere preparation process technology
    • Freitas S, Merkle HP, Gander B. (2005). Microencapsulation by solvent extraction/evaporation: Reviewing the state of the art of microsphere preparation process technology. J Control Release, 102, 313-332.
    • (2005) J. Control Release , vol.102 , pp. 313-332
    • Freitas, S.1    Merkle, H.P.2    Gander, B.3
  • 17
    • 0028046780 scopus 로고
    • Development and characterization of microencapsulated microspheres
    • Göpferich A, Alonso MJ, Langer R. (1994). Development and characterization of microencapsulated microspheres. Pharm Res, 11, 1568-1574.
    • (1994) Pharm. Res. , vol.11 , pp. 1568-1574
    • Göpferich, A.1    Alonso, M.J.2    Langer, R.3
  • 19
    • 68549099546 scopus 로고    scopus 로고
    • Fabrication of biodegradable spheroidal microparticles for drug delivery applications
    • Heslinga MJ, Mastria EM, Eniola-Adefeso O. (2009). Fabrication of biodegradable spheroidal microparticles for drug delivery applications. J Control Release, 138, 235-242.
    • (2009) J. Control Release , Issue.138 , pp. 235-242
    • Heslinga, M.J.1    Mastria, E.M.2    Eniola-Adefeso, O.3
  • 20
    • 0035850221 scopus 로고    scopus 로고
    • On the importance and mechanisms of burst release in matrix-controlled drug delivery systems
    • Huang X, Brazel CS. (2001). On the importance and mechanisms of burst release in matrix-controlled drug delivery systems. J Control Release, 73, 121-136.
    • (2001) J. Control Release , vol.73 , pp. 121-136
    • Huang, X.1    Brazel, C.S.2
  • 21
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • Jain RA. (2000). The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials, 21, 2475-2490.
    • (2000) Biomaterials , vol.21 , pp. 2475-2490
    • Jain, R.A.1
  • 22
    • 0025349621 scopus 로고
    • Microencapsulation using poly(L-lactic acid) IV: Release properties of microcapsules containing phenobarbitone
    • Jalil R, Nixon JR. (1990). Microencapsulation using poly(L-lactic acid) IV: Release properties of microcapsules containing phenobarbitone. J Microencapsul, 7, 53-66.
    • (1990) J. Microencapsul , vol.7 , pp. 53-66
    • Jalil, R.1    Nixon, J.R.2
  • 24
    • 53949092987 scopus 로고    scopus 로고
    • Kinetics of solvent extraction/ evaporation process for PLGA microparticle fabrication
    • Katou H, Wandrey AJ, Gander B. (2008). Kinetics of solvent extraction/ evaporation process for PLGA microparticle fabrication. Int J Pharm, 364, 45-53.
    • (2008) Int. J. Pharm. , vol.364 , pp. 45-53
    • Katou, H.1    Wandrey, A.J.2    Gander, B.3
  • 25
    • 84862880117 scopus 로고    scopus 로고
    • Microencapsulation of dye- and drug-loaded particles for imaging and controlled release of multiple drugs
    • Khung YL, Lee WL, Chui KL, Liu Y, Lim MP, Huang CL, Loo SCJ. (2012). Microencapsulation of dye- and drug-loaded particles for imaging and controlled release of multiple drugs. Adv Healthcare Mater, 1, 159-163.
    • (2012) Adv. Healthcare Mater , Issue.1 , pp. 159-163
    • Khung, Y.L.1    Lee, W.L.2    Chui, K.L.3    Liu, Y.4    Lim, M.P.5    Huang, C.L.6    Loo, S.C.J.7
  • 26
    • 33646176224 scopus 로고    scopus 로고
    • How porosity and size affect the drug release mechanisms from PLGAbased microparticles
    • Klose D, Siepmann F, Elkharraz K, Krenzlin S, Siepmann J. (2006). How porosity and size affect the drug release mechanisms from PLGAbased microparticles. Int J Pharm, 314, 198-206.
    • (2006) Int. J. Pharm. , vol.314 , pp. 198-206
    • Klose, D.1    Siepmann, F.2    Elkharraz, K.3    Krenzlin, S.4    Siepmann, J.5
  • 27
    • 74849119930 scopus 로고    scopus 로고
    • Incorporation of doublewalled microspheres into polymer nerve guides for the sustained delivery of glial cell line-derived neurotrophic factor
    • Kokai LE, Ghaznavi AM, Marra KG. (2010a). Incorporation of doublewalled microspheres into polymer nerve guides for the sustained delivery of glial cell line-derived neurotrophic factor. Biomaterials, 31, 2313-2322.
    • (2010) Biomaterials , vol.31 , pp. 2313-2322
    • Kokai, L.E.1    Ghaznavi, A.M.2    Marra, K.G.3
  • 28
    • 72149103796 scopus 로고    scopus 로고
    • Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double- alled microspheres
    • Kokai LE, Tan H, Jhunjhunwala S, Little SR, Frank JW, Marra KG. (2010b). Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double- alled microspheres. J Control Release, 141, 168-176.
    • (2010) J. Control Release , vol.141 , pp. 168-176
    • Kokai, L.E.1    Tan, H.2    Jhunjhunwala, S.3    Little, S.R.4    Frank, J.W.5    Marra, K.G.6
  • 29
    • 77949916911 scopus 로고    scopus 로고
    • Development of multiple-layer polymeric particles for targeted and controlled drug delivery
    • Koppolu B, Rahimi M, Nattama S, Wadajkar A, Nguyen KT. (2010). Development of multiple-layer polymeric particles for targeted and controlled drug delivery. Nanomedicine, 6, 355-361.
    • (2010) Nanomedicine , vol.6 , pp. 355-361
    • Koppolu, B.1    Rahimi, M.2    Nattama, S.3    Wadajkar, A.4    Nguyen, K.T.5
  • 30
    • 34248658271 scopus 로고    scopus 로고
    • Development of pH- and time-dependent oral microparticles to optimize budesonide delivery to ileum and colon
    • Krishnamachari Y, Madan P, Lin S. (2007). Development of pH- and time-dependent oral microparticles to optimize budesonide delivery to ileum and colon. Int J Pharm, 338, 238-247.
    • (2007) Int. J. Pharm. , vol.338 , pp. 238-247
    • Krishnamachari, Y.1    Madan, P.2    Lin, S.3
  • 31
    • 0032982415 scopus 로고    scopus 로고
    • Effect of manufacturing conditions on the formation of double-walled polymer microspheres
    • Leach K, Noh K, Mathiowitz E. (1999). Effect of manufacturing conditions on the formation of double-walled polymer microspheres. J Microencapsul, 16, 153-167.
    • (1999) J. Microencapsul , vol.16 , pp. 153-167
    • Leach, K.1    Noh, K.2    Mathiowitz, E.3
  • 32
    • 0032213806 scopus 로고    scopus 로고
    • Degradation of double-walled polymer microspheres of PLLA and P(CPP:SA)20:80 I In vitro degradation
    • Leach KJ, Mathiowitz E. (1998). Degradation of double-walled polymer microspheres of PLLA and P(CPP:SA)20:80. I. In vitro degradation. Biomaterials, 19, 1973-1980.
    • (1998) Biomaterials , vol.19 , pp. 1973-1980
    • Leach, K.J.1    Mathiowitz, E.2
  • 33
    • 0032213705 scopus 로고    scopus 로고
    • Degradation of doublewalled polymer microspheres of PLLA and P(CPP:SA)20:80 II In vivo degradation
    • Leach KJ, Takahashi S, Mathiowitz E. (1998). Degradation of doublewalled polymer microspheres of PLLA and P(CPP:SA)20:80. II. In vivo degradation. Biomaterials, 19, 1981-1988.
    • (1998) Biomaterials , vol.19 , pp. 1981-1988
    • Leach, K.J.1    Takahashi, S.2    Mathiowitz, E.3
  • 34
    • 0031575557 scopus 로고    scopus 로고
    • Double-walled microparticles for single shot vaccine
    • Lee HK, Park JH, Kwon KC. (1997). Double-walled microparticles for single shot vaccine. J Control Release, 44, 283-293.
    • (1997) J. Control Release , vol.44 , pp. 283-293
    • Lee, H.K.1    Park, J.H.2    Kwon, K.C.3
  • 35
    • 0037202224 scopus 로고    scopus 로고
    • Double-walled microspheres for the sustained release of a highly water soluble drug: Characterization and irradiation studies
    • Lee TH, Wang J, Wang CH. (2002). Double-walled microspheres for the sustained release of a highly water soluble drug: Characterization and irradiation studies. J Control Release, 83, 437-452.
    • (2002) J. Control Release , vol.83 , pp. 437-452
    • Lee, T.H.1    Wang, J.2    Wang, C.H.3
  • 36
    • 77149137068 scopus 로고    scopus 로고
    • Manipulation of process parameters to achieve different ternary phase microparticle configurations
    • Lee WL, Foo WL, Widjaja E, Loo SC. (2010a). Manipulation of process parameters to achieve different ternary phase microparticle configurations. Acta Biomater, 6, 1342-1352.
    • (2010) Acta Biomater , vol.6 , pp. 1342-1352
    • Lee, W.L.1    Foo, W.L.2    Widjaja, E.3    Loo, S.C.4
  • 37
    • 77954184214 scopus 로고    scopus 로고
    • Formation and degradation of biodegradable triple-layered microparticles
    • Lee WL, Hong M, Widjaja E, Loo SC. (2010b). Formation and degradation of biodegradable triple-layered microparticles. Macromol Rapid Commun, 31, 1193-1200.
    • (2010) Macromol. Rapid. Commun. , vol.31 , pp. 1193-1200
    • Lee, W.L.1    Hong, M.2    Widjaja, E.3    Loo, S.C.4
  • 38
    • 77952468428 scopus 로고    scopus 로고
    • One-step fabrication of triplelayered polymeric microparticles with layer localization of drugs as a novel drug-delivery system
    • Lee WL, Widjaja E, Loo SC. (2010c). One-step fabrication of triplelayered polymeric microparticles with layer localization of drugs as a novel drug-delivery system. Small, 6, 1003-1011.
    • (2010) Small , vol.6 , pp. 1003-1011
    • Lee, W.L.1    Widjaja, E.2    Loo, S.C.3
  • 39
    • 79957474023 scopus 로고    scopus 로고
    • Altering the drug release profiles of double-layered ternary-phase microparticles
    • Lee WL, Loei C, Widjaja E, Loo SC. (2011). Altering the drug release profiles of double-layered ternary-phase microparticles. J Control Release, 151, 229-238.
    • (2011) J. Control Release , vol.151 , pp. 229-238
    • Lee, W.L.1    Loei, C.2    Widjaja, E.3    Loo, S.C.4
  • 42
    • 84857636234 scopus 로고    scopus 로고
    • Designing drug-loaded multilayered polymeric microparticles
    • Lee WL, Widjaja E, Loo SC. (2012c). Designing drug-loaded multilayered polymeric microparticles. J Mater Sci Mater Med, 23, 81-88.
    • (2012) J. Mater. Sci. Mater Med. , vol.23 , pp. 81-88
    • Lee, W.L.1    Widjaja, E.2    Loo, S.C.3
  • 43
    • 84862815807 scopus 로고    scopus 로고
    • Designing multilayered particulate systems for tunable drug release profiles
    • Lee WL, Yu PO, Hong M, Widjaja E, Loo SC. (2012d). Designing multilayered particulate systems for tunable drug release profiles. Acta Biomater, 8, 2271-2278.
    • (2012) Acta Biomater , vol.8 , pp. 2271-2278
    • Lee, W.L.1    Yu, P.O.2    Hong, M.3    Widjaja, E.4    Loo, S.C.5
  • 45
    • 11144285409 scopus 로고    scopus 로고
    • Influence of electron-beam radiation on the hydrolytic degradation behaviour of poly(lactide-coglycolide) (PLGA)
    • Loo SC, Ooi CP, Boey YC. (2005). Influence of electron-beam radiation on the hydrolytic degradation behaviour of poly(lactide-coglycolide) (PLGA). Biomaterials, 26, 3809-3817.
    • (2005) Biomaterials , vol.26 , pp. 3809-3817
    • Loo, S.C.1    Ooi, C.P.2    Boey, Y.C.3
  • 46
    • 33645925016 scopus 로고    scopus 로고
    • Hydrolytic degradation of electron beam irradiated high molecular weight and nonirradiated moderate molecular weight PLLA
    • Loo SC, Tan HT, Ooi CP, Boey YC. (2006). Hydrolytic degradation of electron beam irradiated high molecular weight and nonirradiated moderate molecular weight PLLA. Acta Biomater, 2, 287-296.
    • (2006) Acta Biomater , vol.2 , pp. 287-296
    • Loo, S.C.1    Tan, H.T.2    Ooi, C.P.3    Boey, Y.C.4
  • 48
    • 77953316516 scopus 로고    scopus 로고
    • Drug release from irradiated PLGA and PLLA multi-layered films
    • Loo SC, Tan ZY, Chow YJ, Lin SL. (2010). Drug release from irradiated PLGA and PLLA multi-layered films. J Pharm Sci, 99, 3060-3071.
    • (2010) J. Pharm. Sci. , vol.99 , pp. 3060-3071
    • Loo, S.C.1    Tan, Z.Y.2    Chow, Y.J.3    Lin, S.L.4
  • 50
    • 0032373861 scopus 로고    scopus 로고
    • Preparation of poly(methylmethacrylate) microcapsules with liquid cores
    • Loxley A, Vincent B. (1998). Preparation of Poly(methylmethacrylate) Microcapsules with Liquid Cores. J Colloid Interface Sci, 208, 49-62.
    • (1998) J. Colloid Interface Sci. , vol.208 , pp. 49-62
    • Loxley, A.1    Vincent, B.2
  • 51
    • 33947188787 scopus 로고    scopus 로고
    • Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres
    • Mao S, Xu J, Cai C, Germershaus O, Schaper A, Kissel T. (2007). Effect of WOW process parameters on morphology and burst release of FITC-dextran loaded PLGA microspheres. Int J Pharm, 334, 137-148.
    • (2007) Int. J. Pharm. , vol.334 , pp. 137-148
    • Mao, S.1    Xu, J.2    Cai, C.3    Germershaus, O.4    Schaper, A.5    Kissel, T.6
  • 52
    • 37849034324 scopus 로고    scopus 로고
    • Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method
    • Mao S, Shi Y, Li L, Xu J, Schaper A, Kissel T. (2008). Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method. Eur J Pharm Biopharm, 68, 214-223.
    • (2008) Eur. J. Pharm. Biopharm. , vol.68 , pp. 214-223
    • Mao, S.1    Shi, Y.2    Li, L.3    Xu, J.4    Schaper, A.5    Kissel, T.6
  • 55
    • 23744469867 scopus 로고    scopus 로고
    • Drug release characteristics of multi-reservoir type microspheres with poly(dllactide- co-glycolide) and poly(dl-lactide)
    • Matsumoto A, Matsukawa Y, Suzuki T, Yoshino H. (2005). Drug release characteristics of multi-reservoir type microspheres with poly(dllactide- co-glycolide) and poly(dl-lactide). J Control Release, 106, 172-180.
    • (2005) J. Control Release , vol.106 , pp. 172-180
    • Matsumoto, A.1    Matsukawa, Y.2    Suzuki, T.3    Yoshino, H.4
  • 56
    • 0030844663 scopus 로고    scopus 로고
    • The polymer-alloys method as a new preparation method of biodegradable microspheres: Principle nd application to cisplatin-loaded microspheres
    • Matsumoto A, Matsukawa Y, Suzuki T, Yoshino H, Kobayashi M. (1997). The polymer-alloys method as a new preparation method of biodegradable microspheres: Principle nd application to cisplatin-loaded microspheres. J Control Release, 48, 19-27.
    • (1997) J. Control Release , vol.48 , pp. 19-27
    • Matsumoto, A.1    Matsukawa, Y.2    Suzuki, T.3    Yoshino, H.4    Kobayashi, M.5
  • 57
    • 38349139874 scopus 로고    scopus 로고
    • Engineering biodegradable polyester particles with specific drug targeting and drug release properties
    • Mohamed F, Van der Walle CF. (2008). Engineering biodegradable polyester particles with specific drug targeting and drug release properties. J Pharm Sci, 97, 71-87.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 71-87
    • Mohamed, F.1    Van Der Walle, C.F.2
  • 58
    • 46649095604 scopus 로고    scopus 로고
    • Improved bioavailability of orally delivered insulin using Eudragit-L30D coated PLGA microparticles
    • Naha PC, Kanchan V, Manna PK, Panda AK. (2008). Improved bioavailability of orally delivered insulin using Eudragit-L30D coated PLGA microparticles. J Microencapsul, 25, 248-256.
    • (2008) J. Microencapsul , vol.25 , pp. 248-256
    • Naha, P.C.1    Kanchan, V.2    Manna, P.K.3    Panda, A.K.4
  • 59
    • 11844301238 scopus 로고    scopus 로고
    • Gentamicin-loaded discs and microspheres and their modifications: Characterization and in vitro release
    • Naraharisetti PK, Lew MD, Fu YC, Lee DJ, Wang CH. (2005). Gentamicin-loaded discs and microspheres and their modifications: Characterization and in vitro release. J Control Release, 102, 345-359.
    • (2005) J. Control Release , vol.102 , pp. 345-359
    • Naraharisetti, P.K.1    Lew, M.D.2    Fu, Y.C.3    Lee, D.J.4    Wang, C.H.5
  • 60
    • 0023943907 scopus 로고
    • Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolic) acid microcapsules: Influence of molecular weight and copolymer ratio of polymer
    • Ogawa Y, Yamamoto M, Takada S, Okada H, Shimamoto T. (1988). Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolic) acid microcapsules: Influence of molecular weight and copolymer ratio of polymer. hem Pharm Bull, 36, 1502-1507.
    • (1988) Chem. Pharm. Bull. , vol.36 , pp. 1502-1507
    • Ogawa, Y.1    Yamamoto, M.2    Takada, S.3    Okada, H.4    Shimamoto, T.5
  • 62
    • 0028008642 scopus 로고
    • Double-walled polymer microspheres for controlled drug release
    • Pekarek KJ, Jacob JS, Mathiowitz E. (1994a). Double-walled polymer microspheres for controlled drug release. Nature, 367, 258-260.
    • (1994) Nature , vol.367 , pp. 258-260
    • Pekarek, K.J.1    Jacob, J.S.2    Mathiowitz, E.3
  • 63
    • 0028506914 scopus 로고
    • One-step preparation of double-walled microspheres
    • Pekarek KJ, Jacob JS, Mathiowitz E. (1994b). One-step preparation of double-walled microspheres. Adv Mater, 6, 684-687.
    • (1994) Adv. Mater. , vol.6 , pp. 684-687
    • Pekarek, K.J.1    Jacob, J.S.2    Mathiowitz, E.3
  • 65
    • 27644478212 scopus 로고    scopus 로고
    • Small-molecule release from poly(D,L-lactide)/poly(D,L-lactide-co- glycolide) composite microparticles
    • Pollauf EJ, Kim KK, Pack DW. (2005). Small-molecule release from poly(D,L-lactide)/poly(D,L-lactide-co-glycolide) composite microparticles. J Pharm Sci, 94, 2013-2022.
    • (2005) J. Pharm. Sci. , vol.94 , pp. 2013-2022
    • Pollauf, E.J.1    Kim, K.K.2    Pack, D.W.3
  • 66
    • 31544470339 scopus 로고    scopus 로고
    • Use of thermodynamic parameters for design of double-walled microsphere fabrication methods
    • Pollauf EJ, Pack DW. (2006). Use of thermodynamic parameters for design of double-walled microsphere fabrication methods. Biomaterials, 27, 2898-2906.
    • (2006) Biomaterials , vol.27 , pp. 2898-2906
    • Pollauf, E.J.1    Pack, D.W.2
  • 67
    • 0346104838 scopus 로고    scopus 로고
    • Localization of bovine serum albumin in double-walled microspheres
    • Rahman NA, Mathiowitz E. (2004). Localization of bovine serum albumin in double-walled microspheres. J Control Release, 94, 163-175.
    • (2004) J. Control Release , vol.94 , pp. 163-175
    • Rahman, N.A.1    Mathiowitz, E.2
  • 68
    • 11844272573 scopus 로고    scopus 로고
    • A model for drug release from fast phase inverting injectable solutions
    • Raman C, McHugh AJ. (2005). A model for drug release from fast phase inverting injectable solutions. J Control Release, 102, 145-157.
    • (2005) J. Control Release , vol.102 , pp. 145-157
    • Raman, C.1    McHugh, A.J.2
  • 69
    • 0344734115 scopus 로고    scopus 로고
    • Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region
    • Rodríguez M, Vila-Jato JL, Torres D. (1998). Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region. J Control Release, 55, 67-77.
    • (1998) J. Control Release , vol.55 , pp. 67-77
    • Rodríguez, M.1    Vila-Jato, J.L.2    Torres, D.3
  • 70
  • 72
    • 34648843305 scopus 로고    scopus 로고
    • Effect of the microencapsulation of nanoparticles on the reduction of burst release
    • Sheikh H. (2007). Effect of the microencapsulation of nanoparticles on the reduction of burst release. Int J Pharm, 344, 53-61.
    • (2007) Int. J. Pharm. , vol.344 , pp. 53-61
    • Sheikh, H.1
  • 74
    • 0037472096 scopus 로고    scopus 로고
    • Double walled POE/PLGA microspheres: Encapsulation of watersoluble and water-insoluble proteins and their release properties
    • Shi M, Yang YY, Chaw CS, Goh SH, Moochhala SM, Ng S, Heller J. (2003). Double walled POE/PLGA microspheres: Encapsulation of watersoluble and water-insoluble proteins and their release properties. J Control Release, 89, 167-177.
    • (2003) J. Control Release , vol.89 , pp. 167-177
    • Shi, M.1    Yang, Y.Y.2    Chaw, C.S.3    Goh, S.H.4    Moochhala, S.M.5    Ng, S.6    Heller, J.7
  • 76
    • 0036736395 scopus 로고    scopus 로고
    • Mechanical properties of biodegradable polymer sutures coated with bioactive glass
    • Stamboulis A, Hench LL, Boccaccini AR. (2002). Mechanical properties of biodegradable polymer sutures coated with bioactive glass. J Mater Sci Mater Med, 13, 843-848.
    • (2002) J. Mater Sci. Mater. Med. , vol.13 , pp. 843-848
    • Stamboulis, A.1    Hench, L.L.2    Boccaccini, A.R.3
  • 77
    • 78650320575 scopus 로고    scopus 로고
    • Engineered hydrogen-bonded polymer multilayers: From assembly to biomedical applications
    • Such GK, Johnston AP, Caruso F. (2011). Engineered hydrogen-bonded polymer multilayers: From assembly to biomedical applications. Chem Soc Rev, 40, 19-29.
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 19-29
    • Such, G.K.1    Johnston, A.P.2    Caruso, F.3
  • 78
    • 25844463707 scopus 로고    scopus 로고
    • Fabrication of double-walled microspheres for the sustained release of doxorubicin
    • Tan EC, Lin R, Wang CH. (2005). Fabrication of double-walled microspheres for the sustained release of doxorubicin. J Colloid Interface Sci, 291, 135-143.
    • (2005) J. Colloid Interface Sci. , vol.291 , pp. 135-143
    • Tan, E.C.1    Lin, R.2    Wang, C.H.3
  • 79
    • 70349904929 scopus 로고    scopus 로고
    • Control of layer thickness of onionlike multilayered composite polymer particles prepared by the solvent evaporation method
    • Tanaka T, Saito N, Okubo M. (2009). Control of layer thickness of onionlike multilayered composite polymer particles prepared by the solvent evaporation method. Macromolecules, 42, 7423-7429.
    • (2009) Macromolecules , vol.42 , pp. 7423-7429
    • Tanaka, T.1    Saito, N.2    Okubo, M.3
  • 80
    • 53949085112 scopus 로고    scopus 로고
    • Electrospun nanofibrous polymeric scaffold with targeted drug release profiles for potential application as wound dressing
    • Thakur RA, Florek CA, Kohn J, Michniak BB. (2008). Electrospun nanofibrous polymeric scaffold with targeted drug release profiles for potential application as wound dressing. Int J Pharm, 364, 87-93.
    • (2008) Int. J. Pharm. , vol.364 , pp. 87-93
    • Thakur, R.A.1    Florek, C.A.2    Kohn, J.3    Michniak, B.B.4
  • 81
    • 0014790225 scopus 로고
    • Three-phase interactions in shear and electrical fields
    • Torza S, Mason SG. (1970). Three-phase interactions in shear and electrical fields. J Colloid Interface Sci, 33, 67-83.
    • (1970) J. Colloid Interface Sci. , vol.33 , pp. 67-83
    • Torza, S.1    Mason, S.G.2
  • 83
    • 0037124468 scopus 로고    scopus 로고
    • Sustained release of etanidazole from spray dried microspheres prepared by non-halogenated solvents
    • Wang FJ, Wang CH. (2002). Sustained release of etanidazole from spray dried microspheres prepared by non-halogenated solvents. J Control Release, 81, 263-280.
    • (2002) J. Control Release , vol.81 , pp. 263-280
    • Wang, F.J.1    Wang, C.H.2
  • 84
    • 0038783265 scopus 로고    scopus 로고
    • Structure formation in injectable poly(lactide-co-glycolide) depots
    • Wang L, Kleiner L, Venkatraman S. (2003). Structure formation in injectable poly(lactide-co-glycolide) depots. J Control Release, 90, 345-354.
    • (2003) J. Control Release , vol.90 , pp. 345-354
    • Wang, L.1    Kleiner, L.2    Venkatraman, S.3
  • 85
    • 4544224331 scopus 로고    scopus 로고
    • Drug release from injectable depots: Two different in vitro mechanisms
    • Wang L, Venkatraman S, Kleiner L. (2004). Drug release from injectable depots: Two different in vitro mechanisms. J Control Release, 99, 207-216.
    • (2004) J. Control Release , vol.99 , pp. 207-216
    • Wang, L.1    Venkatraman, S.2    Kleiner, L.3
  • 86
    • 33746847099 scopus 로고    scopus 로고
    • Controlled release of sirolimus from a multilayered PLGA stent matrix
    • Wang X, Venkatraman SS, Boey FY, Loo JS, Tan LP. (2006). Controlled release of sirolimus from a multilayered PLGA stent matrix. Biomaterials, 27, 5588-5595.
    • (2006) Biomaterials , vol.27 , pp. 5588-5595
    • Wang, X.1    Venkatraman, S.S.2    Boey, F.Y.3    Loo, J.S.4    Tan, L.P.5
  • 87
    • 67649108955 scopus 로고    scopus 로고
    • Janus-like polymer particles prepared via internal phase separation from emulsified polymer/oil droplets
    • Wang Y, Guo BH, Wan X, Xu J, Wang X, Zhang YP. (2009). Janus-like polymer particles prepared via internal phase separation from emulsified polymer/oil droplets. Polymer, 50, 3361-3369.
    • (2009) Polymer , vol.50 , pp. 3361-3369
    • Wang, Y.1    Guo, B.H.2    Wan, X.3    Xu, J.4    Wang, X.5    Zhang, Y.P.6
  • 88
    • 67349250740 scopus 로고    scopus 로고
    • A water-in-oil-in-oil-in-water (W/O/O/W) method for producing drug-releasing, double-walled microspheres
    • Wang Z. (2009). A water-in-oil-in-oil-in-water (W/O/O/W) method for producing drug-releasing, double-walled microspheres. Int J Pharm, 374, 90-95.
    • (2009) Int. J. Pharm. , vol.374 , pp. 90-95
    • Wang, Z.1
  • 90
    • 76849114303 scopus 로고    scopus 로고
    • Application of Raman microscopy to biodegradable double-walled microspheres
    • Widjaja E, Lee WL, Loo SC. (2010). Application of Raman microscopy to biodegradable double-walled microspheres. Anal Chem, 82, 1277-1282.
    • (2010) Anal. Chem. , vol.82 , pp. 1277-1282
    • Widjaja, E.1    Lee, W.L.2    Loo, S.C.3
  • 91
    • 0042839403 scopus 로고    scopus 로고
    • Band-target entropy minimization a robust algorithm for pure component spectral recovery application to complex randomized mixtures of six components
    • Widjaja E, Li C, Chew W, Garland M. (2003). Band-target entropy minimization. A robust algorithm for pure component spectral recovery. Application to complex randomized mixtures of six components. Anal Chem, 75, 4499-4507.
    • (2003) Anal. Chem. , vol.75 , pp. 4499-4507
    • Widjaja, E.1    Li, C.2    Chew, W.3    Garland, M.4
  • 92
    • 52449088248 scopus 로고    scopus 로고
    • Biodegradable films developed by electrospray deposition for sustained drug delivery
    • Xie J, Tan JC, Wang CH. (2008). Biodegradable films developed by electrospray deposition for sustained drug delivery. J Pharm Sci, 97, 3109-3122.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 3109-3122
    • Xie, J.1    Tan, J.C.2    Wang, C.H.3
  • 93
    • 0037423784 scopus 로고    scopus 로고
    • POE/ PLGA composite microspheres: Formation and in vitro behavior of double walled microspheres
    • Yang YY, Shi M, Goh SH, Moochhala SM, Ng S, Heller J. (2003). POE/ PLGA composite microspheres: Formation and in vitro behavior of double walled microspheres. J Control Release, 88, 201-213.
    • (2003) J. Control Release , vol.88 , pp. 201-213
    • Yang, Y.Y.1    Shi, M.2    Goh, S.H.3    Moochhala, S.M.4    Ng, S.5    Heller, J.6
  • 94
    • 84863032547 scopus 로고    scopus 로고
    • Controlled-release and preserved bioactivity of proteins from (self-assembled) core-shell double-walled microspheres
    • Yuan W, Liu Z. (2012). Controlled-release and preserved bioactivity of proteins from (self-assembled) core-shell double-walled microspheres. Int J Nanomedicine, 7, 257-270.
    • (2012) Int. J. Nanomedicine , Issue.7 , pp. 257-270
    • Yuan, W.1    Liu, Z.2
  • 95
    • 58149152977 scopus 로고    scopus 로고
    • Development of protein delivery microsphere system by a novel S/O/O/W multi-emulsion
    • Yuan W, Wu F, Guo M, Jin T. (2009). Development of protein delivery microsphere system by a novel S/O/O/W multi-emulsion. Eur J Pharm Sci, 36, 212-218.
    • (2009) Eur. J. Pharm. Sci. , vol.36 , pp. 212-218
    • Yuan, W.1    Wu, F.2    Guo, M.3    Jin, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.