PLGA-based microparticles: Elucidation of mechanisms and a new, simple mathematical model quantifying drug release

European Journal of Pharmaceutical Sciences

Volumn 15, Issue 4, 2002, Pages 355-366

  Faisant, N ^a   Siepmann, J ^a,b   Benoit, J P ^a  

^a UNIVERSITÉ D'ANGERS   (France)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Diffusion; Mathematical modeling; Microparticle; PLGA; Release mechanism

Indexed keywords

BIOCOMPATIBILITY; CONTROLLED DRUG DELIVERY; DRUG INFUSION; MATHEMATICAL MODELS;

DRUG RELEASE PATTERNS;

DRUG PRODUCTS;

ANTINEOPLASTIC AGENT; BUFFER; FLUOROURACIL; NANOPARTICLE; PHOSPHATE; POLYGLACTIN; RESOMER; RESOMER 506; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; GAMMA IRRADIATION; GEL PERMEATION CHROMATOGRAPHY; MATHEMATICAL MODEL; MICROPARTICLE; PARTICLE SIZE; PHYSICAL CHEMISTRY; PHYSICAL PHENOMENA; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

BUFFERS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, GEL; DIFFUSION; EXCIPIENTS; GAMMA RAYS; KINETICS; LACTIC ACID; MICROSPHERES; MODELS, CHEMICAL; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; SOLUBILITY; TEMPERATURE;

EID: 0036231029     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(02)00023-4     Document Type: Article

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