Composite microparticles with in vivo reduction of the burst release effect

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 73, Issue 3, 2009, Pages 337-344

  Sheikh Hassan, A ^a   Sapin, A ^a   Lamprecht, A ^b   Emond, E ^a   El Ghazouani, F ^a   Maincent, P ^a  

^a UNIVERSITÉ DE LORRAINE   (France)

^b Laboratory of Pharmaceutical Engineering   (France)

Author keywords

Burst effect; Composite microparticles; Ibuprofen; In vitro; In vivo; Poly( caprolactone); Poly(lactic co glycolic) acid

Indexed keywords

ACETIC ACID ETHYL ESTER; IBUPROFEN; NANOCOMPOSITE; NANOPARTICLE; PHOSPHATE BUFFERED SALINE; POLYCAPROLACTONE; POLYGLACTIN; POLYMER; RESOMER; SOLVENT;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIODEGRADABILITY; COMPOSITE MATERIAL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; NANOENCAPSULATION; NONHUMAN; RAT; SUSTAINED DRUG RELEASE; TIME TO MAXIMUM PLASMA CONCENTRATION; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HYDROPHOBICITY; IBUPROFEN; INJECTIONS, SUBCUTANEOUS; LACTIC ACID; MALE; MICROSPHERES; NANOPARTICLES; POLYESTERS; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, WISTAR;

EID: 70350431305     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.07.009     Document Type: Article

References (42)

1. Siepmann J., Faisant N., Akiki J., Richard J., and Benoit J.P. Effect of the size of biodegradable microparticles on drug release: experiment and theory. J. Control. Rel. 96 (2004) 123-134
2. Sant S., Nadeau V., and Hildgen P. Effect of porosity on the release kinetics of propafenone-loaded PEG-g-PLA nanoparticles. J. Control. Rel. 107 (2005) 203-214
3. Jain R.A. The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21 (2000) 2475-2490
4. Thompson C.J., Hansford D., Higgins S., Rostron C., Hutcheon G.A., and Munday D.L. Evaluation of ibuprofen-loaded microspheres prepared from novel copolyesters. Int. J. Pharm. 329 (2007) 53-61
5. Wang C., Ye W., Zheng Y., Liu X., and Tong Z. Fabrication of drug-loaded biodegradable microcapsules for controlled release by combination of solvent evaporation and layer-by-layer self-assembly. Int. J. Pharm. 338 (2007) 165-173
6. Bodmeier R., and Chen H. Preparation and characterization of microspheres containing the anti-inflammatory agents, indomethacin, ibuprofen, and ketoprofen. J. Control. Rel. 10 (1989) 167-175
7. Hombreiro-Pérez M., Siepmann J., Zinutti C., Lamprecht A., Ubrich N., Hoffman M., Bodmeier R., and Maincent P. Non-degradable microparticles containing a hydrophilic and/or a lipophilic drug: preparation, characterization and drug release modeling. J. Control. Rel. 88 (2003) 413-428
8. Karasulu E., Yeşim Karasulu H., Ertan G., Kirilmaz L., and Güneri T. Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates. Eur. J. Pharm. Sci. 19 (2003) 99-104
9. Tice T.R., and Cowsar D.R. Biodegradable controlled-release parenteral systems. Pharm. Technol. 11 (1984) 26-36
10. Okada H. One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate. Adv. Drug Deliv. Rev. 28 (1997) 43-70
11. Okada H., Doken Y., Ogawa Y., and Toguchi H. Preparation of three-month depot injectable microspheres of leuprorelin acetate using biodegradable polymers. Pharm. Res. 11 (1994) 1143-1147
12. Jiang W., and Schwendeman S.P. Stabilization and controlled release of bovine serum albumin encapsulated in poly (d,l-lactide) and poly(ethylene glycol) microsphere blends. Pharm. Res. 18 (2001) 878-885
13. Wang J., Wang B.W., and Schwendeman S.P. Mechanistic evaluation of the glucose-induced reduction in initial burst release of octreotide acetate from poly(d,l-lactide-co-glycolide) microspheres. Biomaterials 25 (2004) 1919-1927
14. Fernandez-Carballido A., Herrero-Vanrell R., Molina-Martinez I.T., and Pastoriza P. Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration. Effect of labrafil addition on release in vitro. Int. J. Pharm. 279 (2004) 33-41
15. Hanes J., Chiba M., and Langer R. Degradation of porous poly(anhydride-co-imide) microspheres and implications for controlled macromolecule delivery. Biomaterials 19 (1998) 163-172
16. Yang Y.Y., Wan J.P., Chung T.S., Pallathadka P.K., Ng S., and Heller J. POE-PEG-POE triblock copolymeric microspheres containing protein: I. preparation and characterization. J. Control. Rel. 75 (2001) 15-128
17. Castellanos I.J., Carrasquillo K.G., Lopez J.D., Alvarez M., and Griebenow K. Encapsulation of bovine serum albumin in poly(lactide-co-glycolide) microspheres by the solid-in-oil-in-water technique. J. Pharm. Pharmacol. 53 (2001) 167-178
18. Thote A.J., and Gupta R.B. Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release. Nanomedicine 1 (2005) 85-90
19. Lalla J.K., and Snape K. Biodegradable microspheres of poly(d,l-lactic acid) containing piroxicam as a model drug for controlled release via the parenteral route. J. Microencapsul. 10 (1993) 449-460
20. Leo E., Forni F., and Bernabei M.T. Surface drug removal from ibuprofen-loaded PLA microspheres. Int. J. Pharm. 196 (2000) 1-9
21. Sheikh Hasan A., Socha M., Lamprecht A., Ghazouani F.E., Sapin A., Hoffman M., Maincent P., and Ubrich N. Effect of the microencapsulation of nanoparticles on the reduction of burst release. Int. J. Pharm. 344 (2007) 53-61
22. Benita S., Benoit J.P., Puisieux F., and Thies C. Characterisation of drug-loaded poly(d,l-lactide) microspheres. J. Pharm. Sci. 73 (1984) 1721-1724
23. Li J.K., Wang N., and Wu X.S. A novel biodegradable system based on gelatin nanoparticles and poly(lactic-co-glycolic acid) microspheres for protein and peptide drug delivery. J. Pharm. Sci. 86 (1997) 891-895
24. Leach W.T., Simpson D.T., Val T.N., Anuta E.C., Yu Z., Williams III R.O., and Johnston K.P. Uniform encapsulation of stable protein nanoparticles produced by spray freezing for the reduction of burst release. J. Pharm. Sci. 94 (2005) 56-69
25. Bhavsar M.D., and Amiji M.M. Gastrointestinal distribution and in vivo gene transfection studies with nanoparticles-in-microsphere oral system (NiMOS). J. Control. Rel. 119 (2007) 339-348
26. Lamprecht A., Yamamoto H., Takeuchi H., and Kawashima Y. A pH-sensitive microsphere system for the colon delivery of tacrolimus containing nanoparticles. J. Control. Rel. 104 (2005) 337-346
27. Grenha A., Seijo B., and Remunan-Lopez C. Microencapsulated chitosan nanoparticles for lung protein delivery. Eur. J. Pharm. Sci. 25 (2005) 427-437
28. Aranda J.V., and Thomas R. Systematic review: intravenous Ibuprofen in preterm newborns. Semin. Perinatol. 30 (2006) 114-120
29. Jiang B., Hu L., Gao C., and Shen J. Ibuprofen-loaded nanoparticles prepared by a co-precipitation method and their release properties. Int. J. Pharm. 304 (2005) 220-230
30. Borovac T., Pelage J.P., Kasselouri A., Prognon P., Guiffant G., and Laurent A. Release of ibuprofen from beads for embolization: in vitro and in vivo studies. J. Control. Rel. 115 (2006) 266-2674
31. Pignatello R., Bucolo C., Ferrara P., Maltese A., Puleo A., and Puglisi G. Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen. Eur. J. Pharm. Sci. 16 (2002) 53-61
32. Hoffart V., Ubrich N., Simonin C., Babak V., Vigneron C., Hoffman M., Lecompte T., and Maincent P. Low molecular weight heparin-loaded polymeric nanoparticles: formulation, characterization, and release characteristics. Drug. Dev. Ind. Pharm. 28 (2002) 1091-2000
33. Freytag T., Dashevsky A., Tillman L., Hardee G.E., and Bodmeier R. Improvement of the encapsulation efficiency of oligonucleotide-containing biodegradable microspheres. J. Control. Rel. 69 (2000) 197-207
34. Wang N., Wu X.S., and Li J.K. A heterogeneously structured composite based on poly(lactic-co-glycolic acid) microspheres and poly(vinyl alcohol) hydrogel nanoparticles for long-term protein drug delivery. Pharm. Res. 16 (1999) 1430-1435
35. Bolourtchian N., Karimi K., and Aboofazeli R. Preparation and characterization of ibuprofen microspheres. J. Microencapsul. 22 (2005) 529-538
36. Zhu K.J., Li Y., Jiang H.L., Yasuda H., Ichimaru A., Yamamoto K., Lecomte P., and Jerome R. Preparation, characterization and in vitro release properties of ibuprofen-loaded microspheres based on polylactide, poly (epsilon-caprolactone) and their copolymers. J. Microencapsul. 22 (2005) 25-36
37. Karttunen P., Saano V., Paronen P., Peura P., and Vidgren M. Pharmacokinetics of ibuprofen in man: a single-dose comparison of two over-the-counter, 200 mg preparations. Int. J. Clin. Pharmacol. Ther. Toxicol. 28 (1990) 251-255
38. Mainardes R.M., and Evangelista R.C. Praziquantel-loaded PLGA nanoparticles: preparation and characterization. J. Microencapsul. 22 (2005) 13-24
39. Yeo Y., and Park K. Control of encapsulation efficiency and initial burst in polymeric microparticle systems. Arch. Pharm. Res. 27 (2004) 1-12
40. Mao S., Shi Y., Li L., Xu J., Schaper A., and Kissel T. Effects of process and formulation parameters on characteristics and internal morphology of poly(d,l-lactide-co-glycolide) microspheres formed by the solvent evaporation method. Eur. J. Pharm. Biopharm. 68 (2008) 214-223
41. Saravanan M., Bhaskar K., Srinivasa Rao G., and Dhanaraju M.D. Ibuprofen-loaded ethylcellulose/polystyrene microspheres: an approach to get prolonged drug release with reduced burst effect and low ethylcellulose content. J. Microencapsul. 20 (2003) 289-302
42. Sheikh Hassan A., Bolzan C., Sapin A., Ubrich N., Maincent P., and Leroy P. Simple and sensitive HPLC method with fluorescence detection for the measurement of ibuprofen in rat plasma, Application to a long-lasting dosage form. Drug Dev. Ind. Pharm. 34 (2008) 1064-1070