Computational methods to predict therapeutic protein aggregation

Methods in Molecular Biology

Volumn 899, Issue , 2012, Pages 425-451

  Buck, Patrick M ^a   Kumar, Sandeep ^a   Wang, Xiaoling ^a   Agrawal, Neeraj J ^b   Trout, Bernhardt L ^b   Singh, Satish K ^a  

^a PFIZER INC   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Aggregation prone regions; Biotherapeutics; Computational prediction; Monoclonal antibodies

Indexed keywords

MONOCLONAL ANTIBODY; PROTEIN;

ARTICLE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; HUMAN; ISOLATION AND PURIFICATION; KINETICS; PROTEIN CONFORMATION; THEORETICAL MODEL;

ANTIBODIES, MONOCLONAL; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; HUMANS; KINETICS; MODELS, MOLECULAR; MODELS, THEORETICAL; PROTEIN CONFORMATION; PROTEINS;

EID: 84864150265     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-921-1_26     Document Type: Article

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