Identification and Impact of Aggregation-Prone Regions in Proteins and Therapeutic Monoclonal Antibodies

Aggregation of Therapeutic Proteins

Volumn , Issue , 2010, Pages 103-118

  Kumar, Sandeep ^a   Wang, Xiaoling ^a   Singh, Satish K ^a  

^a PFIZER INC   (United States)

Author keywords

APR prediction in proteins and biotherapeutics; Identification and impact of aggregation prone regions in protein and therapeutic monoclonal antibodies; Protein native state stability improvements via elimination mitigation of APRs, increasing shelf life of product

Indexed keywords

EID: 77955466435     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470769829.ch3     Document Type: Chapter

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