Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic β2-microglobulin variant

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 4, 2011, Pages 1314-1319

  Domanska, Katarzyna ^a,b   Vanderhaegen, Saskia ^a,b   Srinivasan, Vasundara ^a,b   Pardon, Els ^a,b   Dupeux, Florine ^c   Marquez, Jose A ^c   Giorgetti, Sofia ^d   Stoppini, Monica ^d   Wyns, Lode ^a,b   Bellotti, Vittorio ^d   Steyaert, Jan ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

Amyloid fibrils; Crystallization chaperones; Dialysis related amyloidosis; Prefibrillar intermediates

Indexed keywords

AMYLOID; BETA 2 MICROGLOBULIN; CHAPERONE;

ANIMAL EXPERIMENT; ARTICLE; ARTIODACTYLA; CAMEL; CRYSTAL STRUCTURE; FIBER; LLAMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMYLOID; ANIMALS; ANTIBODIES; ANTIBODY AFFINITY; BETA 2-MICROGLOBULIN; CAMELIDS, NEW WORLD; CAMELS; CRYSTALLOGRAPHY, X-RAY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; MUTATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE;

EID: 79952152956     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1008560108     Document Type: Article

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