Multi-variate approach to global protein aggregation behavior and kinetics: Effects of pH, NaCl, and temperature for α-chymotrypsinogen A

Journal of Pharmaceutical Sciences

Volumn 99, Issue 2, 2010, Pages 645-662

  Li, Yi ^a   Ogunnaike, Babatunde A ^a   Roberts, Christopher J ^a  

^a University of Delaware   (United States)

Author keywords

Protein aggregation; Protein formulation; Stability

Indexed keywords

CHYMOTRYPSINOGEN; PROTEIN; SODIUM CHLORIDE;

ARTICLE; CIRCULAR DICHROISM; FLUORESCENCE SPECTROSCOPY; GEL PERMEATION CHROMATOGRAPHY; KINETICS; LASER; LIGHT SCATTERING; OSMOSIS; PH; PHASE SEPARATION; POLYMERIZATION; PROTEIN AGGREGATION; STATISTICAL MODEL; TEMPERATURE;

EID: 74049123780     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21869     Document Type: Article

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