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Volumn 133, Issue 7, 2012, Pages 508-522

Accumulation of annexin A5 at the nuclear envelope is a biomarker of cellular aging

Author keywords

Annexin A5; Biomarker; Cell cycle; Cellular aging; Human skin; Senescence

Indexed keywords

BETA GALACTOSIDASE; LIPOCORTIN 5; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P21; SMALL INTERFERING RNA;

EID: 84864071415     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2012.06.003     Document Type: Article
Times cited : (20)

References (107)
  • 1
    • 0028286395 scopus 로고
    • The sole DNA damage induced by bromodeoxyuridine is sufficient for initiation of both aging and carcinogenesis in vivo
    • Anisimov V.N. The sole DNA damage induced by bromodeoxyuridine is sufficient for initiation of both aging and carcinogenesis in vivo. Annals of the New York Academy of Sciences 1994, 719:494-501.
    • (1994) Annals of the New York Academy of Sciences , vol.719 , pp. 494-501
    • Anisimov, V.N.1
  • 4
    • 0030607223 scopus 로고    scopus 로고
    • Subcellular localization of annexin V in human foreskin fibroblasts: nuclear localization depends on growth state
    • Barwise J.L., Walker J.H. Subcellular localization of annexin V in human foreskin fibroblasts: nuclear localization depends on growth state. FEBS Letters 1996, 394:213-216.
    • (1996) FEBS Letters , vol.394 , pp. 213-216
    • Barwise, J.L.1    Walker, J.H.2
  • 6
    • 79957880743 scopus 로고    scopus 로고
    • Cell cycle arrest is not senescence
    • Blagosklonny M.V. Cell cycle arrest is not senescence. Aging (Albany, NY) 2011, 3:94-101.
    • (2011) Aging (Albany, NY) , vol.3 , pp. 94-101
    • Blagosklonny, M.V.1
  • 10
    • 0029921312 scopus 로고    scopus 로고
    • Molecular markers of senescence in fibroblast-like cultures
    • Cristofalo V.J., Pignolo R.J. Molecular markers of senescence in fibroblast-like cultures. Experimental Gerontology 1996, 31:111-123.
    • (1996) Experimental Gerontology , vol.31 , pp. 111-123
    • Cristofalo, V.J.1    Pignolo, R.J.2
  • 12
    • 72949096792 scopus 로고    scopus 로고
    • Senescence in tumours: evidence from mice and humans
    • Collado M., Serrano M. Senescence in tumours: evidence from mice and humans. Nature Reviews Cancer 2010, 10:51-57.
    • (2010) Nature Reviews Cancer , vol.10 , pp. 51-57
    • Collado, M.1    Serrano, M.2
  • 13
    • 77949881221 scopus 로고    scopus 로고
    • The senescence-associated secretory phenotype: the dark side of tumor suppression
    • Coppé J.P., Desprez P.Y., Krtolica A., Campisi J. The senescence-associated secretory phenotype: the dark side of tumor suppression. Annual Review of Pathology 2010, 5:99-118.
    • (2010) Annual Review of Pathology , vol.5 , pp. 99-118
    • Coppé, J.P.1    Desprez, P.Y.2    Krtolica, A.3    Campisi, J.4
  • 15
    • 45849099050 scopus 로고    scopus 로고
    • Living on a break: cellular senescence as a DNA-damage response
    • d'Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nature Reviews Cancer 2008, 8:512-522.
    • (2008) Nature Reviews Cancer , vol.8 , pp. 512-522
    • d'Adda di Fagagna, F.1
  • 16
    • 63549135460 scopus 로고    scopus 로고
    • Meta-analysis of age-related gene expression profiles identifies common signatures of aging
    • de Magalhães J.P., Curado J., Church G.M. Meta-analysis of age-related gene expression profiles identifies common signatures of aging. Bioinformatics 2009, 25:875-881.
    • (2009) Bioinformatics , vol.25 , pp. 875-881
    • de Magalhães, J.P.1    Curado, J.2    Church, G.M.3
  • 17
    • 74949127989 scopus 로고    scopus 로고
    • Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo
    • Debacq-Chainiaux F., Erusalimsky J.D., Campisi J., Toussaint O. Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nature Protocols 2009, 4:1798-1806.
    • (2009) Nature Protocols , vol.4 , pp. 1798-1806
    • Debacq-Chainiaux, F.1    Erusalimsky, J.D.2    Campisi, J.3    Toussaint, O.4
  • 18
    • 0027970713 scopus 로고
    • DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts
    • Di Leonardo A., Linke S.P., Clarkin K., Wahl G.M. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. Genes and Development 1994, 8:2540-2551.
    • (1994) Genes and Development , vol.8 , pp. 2540-2551
    • Di Leonardo, A.1    Linke, S.P.2    Clarkin, K.3    Wahl, G.M.4
  • 21
    • 33646235625 scopus 로고    scopus 로고
    • Protein expression dynamics during replicative senescence of endothelial cells studied by 2-D difference in-gel electrophoresis
    • Eman M.R., Regan-Klapisz E., Pinkse M.W., Koop I.M., Haverkamp J., Heck A.J., Verkleij A.J., Post J.A. Protein expression dynamics during replicative senescence of endothelial cells studied by 2-D difference in-gel electrophoresis. Electrophoresis 2006, 27:1669-1682.
    • (2006) Electrophoresis , vol.27 , pp. 1669-1682
    • Eman, M.R.1    Regan-Klapisz, E.2    Pinkse, M.W.3    Koop, I.M.4    Haverkamp, J.5    Heck, A.J.6    Verkleij, A.J.7    Post, J.A.8
  • 23
    • 79955017452 scopus 로고    scopus 로고
    • P38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
    • Freund A., Patil C.K., Campisi J. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO Journal 2011, 30:1536-1548.
    • (2011) EMBO Journal , vol.30 , pp. 1536-1548
    • Freund, A.1    Patil, C.K.2    Campisi, J.3
  • 25
    • 34648816970 scopus 로고    scopus 로고
    • Cellular senescence and chromatin structure
    • Funayama R., Ishikawa F. Cellular senescence and chromatin structure. Chromosoma 2007, 116:431-440.
    • (2007) Chromosoma , vol.116 , pp. 431-440
    • Funayama, R.1    Ishikawa, F.2
  • 27
    • 0036083696 scopus 로고    scopus 로고
    • Annexins: from structure to function
    • Gerke V., Moss S.E. Annexins: from structure to function. Physiological Reviews 2002, 82:331-371.
    • (2002) Physiological Reviews , vol.82 , pp. 331-371
    • Gerke, V.1    Moss, S.E.2
  • 29
    • 0029670840 scopus 로고    scopus 로고
    • Regulation of pl6CDKN2 expression and its implications for cell immortalization and senescence
    • Hara E., Smith R., Parry D., Tahara H., Stone S., Peters G. Regulation of pl6CDKN2 expression and its implications for cell immortalization and senescence. Molecular and Cellular Biology 1996, 16:859-867.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 859-867
    • Hara, E.1    Smith, R.2    Parry, D.3    Tahara, H.4    Stone, S.5    Peters, G.6
  • 30
    • 0025279931 scopus 로고
    • Telomeres shorten during aging of human fibroblasts
    • Harley C.B., Futcher A.B., Greider C.W. Telomeres shorten during aging of human fibroblasts. Nature 1990, 345:458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 31
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Experimental Cell Research 1961, 25:585-621.
    • (1961) Experimental Cell Research , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 32
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick L. The limited in vitro lifetime of human diploid cell strains. Experimental Cell Research 1965, 37:614-636.
    • (1965) Experimental Cell Research , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 34
    • 2442511752 scopus 로고    scopus 로고
    • Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)
    • Herbig U., Jobling W.A., Chen B.P., Chen D.J., Sedivy J.M. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). Molecular Cell 2004, 14:501-513.
    • (2004) Molecular Cell , vol.14 , pp. 501-513
    • Herbig, U.1    Jobling, W.A.2    Chen, B.P.3    Chen, D.J.4    Sedivy, J.M.5
  • 37
    • 73749086319 scopus 로고    scopus 로고
    • Senescence and life span
    • Hornsby P.J. Senescence and life span. Pflugers Arch 2010, 459:291-299.
    • (2010) Pflugers Arch , vol.459 , pp. 291-299
    • Hornsby, P.J.1
  • 39
    • 0032104625 scopus 로고    scopus 로고
    • The making and the breaking of senescence: changes of gene expression during cellular aging and immortalization
    • Jansen-Dürr P. The making and the breaking of senescence: changes of gene expression during cellular aging and immortalization. Experimental Gerontology 1998, 33:291-301.
    • (1998) Experimental Gerontology , vol.33 , pp. 291-301
    • Jansen-Dürr, P.1
  • 42
    • 0030917324 scopus 로고    scopus 로고
    • Altered distribution of the promyelocytic leukemia-associated protein is associated with cellular senescence
    • Jiang W.Q., Ringertz N. Altered distribution of the promyelocytic leukemia-associated protein is associated with cellular senescence. Cell Growth and Differentiation 1997, 8:513-522.
    • (1997) Cell Growth and Differentiation , vol.8 , pp. 513-522
    • Jiang, W.Q.1    Ringertz, N.2
  • 45
    • 0037192462 scopus 로고    scopus 로고
    • Senescence induced by altered telomere state, not telomere loss
    • Karlseder J., Smogorzewska A., de Lange T. Senescence induced by altered telomere state, not telomere loss. Science 2002, 295:2446-2449.
    • (2002) Science , vol.295 , pp. 2446-2449
    • Karlseder, J.1    Smogorzewska, A.2    de Lange, T.3
  • 46
    • 33747372839 scopus 로고    scopus 로고
    • Protein kinase C delta (deltaPKC)-annexin V interaction: a required step in deltaPKC translocation and function
    • Kheifets V., Bright R., Inagaki K., Schechtman D., Mochly-Rosen D. Protein kinase C delta (deltaPKC)-annexin V interaction: a required step in deltaPKC translocation and function. Journal of Biological Chemistry 2006, 281:23218-23226.
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 23218-23226
    • Kheifets, V.1    Bright, R.2    Inagaki, K.3    Schechtman, D.4    Mochly-Rosen, D.5
  • 47
    • 79851493300 scopus 로고    scopus 로고
    • Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a)
    • Kosar M., Bartkova J., Hubackova S., Hodny Z., Lukas J., Bartek J. Senescence-associated heterochromatin foci are dispensable for cellular senescence, occur in a cell type- and insult-dependent manner and follow expression of p16(ink4a). Cell Cycle 2011, 10:457-468.
    • (2011) Cell Cycle , vol.10 , pp. 457-468
    • Kosar, M.1    Bartkova, J.2    Hubackova, S.3    Hodny, Z.4    Lukas, J.5    Bartek, J.6
  • 51
    • 58849154235 scopus 로고    scopus 로고
    • Senescence-messaging secretome: SMS-ing cellular stress
    • Kuilman T., Peeper D.S. Senescence-messaging secretome: SMS-ing cellular stress. Nature Reviews Cancer 2009, 9:81-94.
    • (2009) Nature Reviews Cancer , vol.9 , pp. 81-94
    • Kuilman, T.1    Peeper, D.S.2
  • 52
    • 0028924516 scopus 로고
    • Increased p53 protein associated with aging in human diploid fibroblasts
    • Kulju K.S., Lehman J.M. Increased p53 protein associated with aging in human diploid fibroblasts. Experimental Cell Research 1995, 217:336-345.
    • (1995) Experimental Cell Research , vol.217 , pp. 336-345
    • Kulju, K.S.1    Lehman, J.M.2
  • 55
    • 38549092474 scopus 로고    scopus 로고
    • Membrane recognition by phospholipid-binding domains
    • Lemmon M.A. Membrane recognition by phospholipid-binding domains. Nature Reviews Molecular Cell Biology 2008, 9:99-111.
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , pp. 99-111
    • Lemmon, M.A.1
  • 57
  • 58
    • 34249672067 scopus 로고    scopus 로고
    • Beta-galactosidase activity as a biomarker of replicative senescence during the course of human fibroblast cultures
    • Maier A.B., Westendorp R.G., van Heemst D. Beta-galactosidase activity as a biomarker of replicative senescence during the course of human fibroblast cultures. Annals of the New York Academy of Sciences 2007, 1100:323-332.
    • (2007) Annals of the New York Academy of Sciences , vol.1100 , pp. 323-332
    • Maier, A.B.1    Westendorp, R.G.2    van Heemst, D.3
  • 59
    • 0018358261 scopus 로고
    • Senescent human diploid cells in culture: survival, DNA synthesis and morphology
    • Matsumura T., Zerrudo Z., Hayflick L. Senescent human diploid cells in culture: survival, DNA synthesis and morphology. Journal of Gerontology 1979, 34:328-334.
    • (1979) Journal of Gerontology , vol.34 , pp. 328-334
    • Matsumura, T.1    Zerrudo, Z.2    Hayflick, L.3
  • 62
    • 77950267128 scopus 로고    scopus 로고
    • Polyploidy: the link between senescence and cancer
    • Mosieniak G., Sikora E. Polyploidy: the link between senescence and cancer. Current Pharmaceutical Design 2010, 16:734-740.
    • (2010) Current Pharmaceutical Design , vol.16 , pp. 734-740
    • Mosieniak, G.1    Sikora, E.2
  • 69
    • 0021350634 scopus 로고
    • Progressive loss of the response of senescing WI-38 cells to platelet-derived growth factor, epidermal growth factor, insulin, transferrin, and dexamethasone
    • Phillips P.D., Kaji K., Cristofalo V.J. Progressive loss of the response of senescing WI-38 cells to platelet-derived growth factor, epidermal growth factor, insulin, transferrin, and dexamethasone. Journal of Gerontology 1984, 39:11-17.
    • (1984) Journal of Gerontology , vol.39 , pp. 11-17
    • Phillips, P.D.1    Kaji, K.2    Cristofalo, V.J.3
  • 71
    • 0020001290 scopus 로고
    • Radiation-induced shortening of the lifespan of D. melanogaster. 2. Sensitizing effect of 5-bromo-2-deoxyuridine
    • Potapenko A.I., Akif'ev A.P., Ivanov V.I. Radiation-induced shortening of the lifespan of D. melanogaster. 2. Sensitizing effect of 5-bromo-2-deoxyuridine. Radiobiologiia 1982, 22:318-322.
    • (1982) Radiobiologiia , vol.22 , pp. 318-322
    • Potapenko, A.I.1    Akif'ev, A.P.2    Ivanov, V.I.3
  • 72
    • 41549149451 scopus 로고    scopus 로고
    • Cellular senescence in vivo: a barrier to tumorigenesis
    • Prieur A., Peeper D.S. Cellular senescence in vivo: a barrier to tumorigenesis. Current Opinion in Cell Biology 2008, 20:150-155.
    • (2008) Current Opinion in Cell Biology , vol.20 , pp. 150-155
    • Prieur, A.1    Peeper, D.S.2
  • 76
    • 0022387184 scopus 로고
    • Isolation and partial purification of a novel anticoagulant from arteries of human umbilical cord
    • Reutelingsperger C.P., Hornstra G., Hemker H.C. Isolation and partial purification of a novel anticoagulant from arteries of human umbilical cord. European Journal of Biochemistry 1985, 151:625-629.
    • (1985) European Journal of Biochemistry , vol.151 , pp. 625-629
    • Reutelingsperger, C.P.1    Hornstra, G.2    Hemker, H.C.3
  • 78
  • 84
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M., Lin A.W., McCurrach M.E., Beach D., Lowe S.W. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997, 88:593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 86
    • 0026054961 scopus 로고
    • A role for both RB and p53 in the regulation of human cellular senescence
    • Shay J.W., Pereira-Smith O.M., Wright W.E. A role for both RB and p53 in the regulation of human cellular senescence. Experimental Cell Research 1991, 196:33-39.
    • (1991) Experimental Cell Research , vol.196 , pp. 33-39
    • Shay, J.W.1    Pereira-Smith, O.M.2    Wright, W.E.3
  • 88
    • 0023722558 scopus 로고
    • Strategies and criteria for the development of molecular biomarkers of senescence
    • Shmookler Reis R.J. Strategies and criteria for the development of molecular biomarkers of senescence. Experimental Gerontology 1988, 23:271-280.
    • (1988) Experimental Gerontology , vol.23 , pp. 271-280
    • Shmookler Reis, R.J.1
  • 90
    • 0033013980 scopus 로고    scopus 로고
    • Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts
    • Stein G.H., Drullinger L.F., Soulard A., Dulić V. Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts. Molecular and Cellular Biology 1999, 19:2109-2117.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 2109-2117
    • Stein, G.H.1    Drullinger, L.F.2    Soulard, A.3    Dulić, V.4
  • 91
    • 0036354627 scopus 로고    scopus 로고
    • Synergistic induction of the senescence-associated genes by 5-bromodeoxyuridine and AT-binding ligands in HeLa cells
    • Suzuki T., Michishita E., Ogino H., Fujii M., Ayusawa D. Synergistic induction of the senescence-associated genes by 5-bromodeoxyuridine and AT-binding ligands in HeLa cells. Experimental Cell Research 2002, 276:174-184.
    • (2002) Experimental Cell Research , vol.276 , pp. 174-184
    • Suzuki, T.1    Michishita, E.2    Ogino, H.3    Fujii, M.4    Ayusawa, D.5
  • 95
    • 0028946009 scopus 로고
    • Increase in expression level of p21sdil/cipl/wafl with increasing division age in both normal and SV40-transformed human fibroblasts
    • Tahara H., Sato E., Noda A., Ide T. Increase in expression level of p21sdil/cipl/wafl with increasing division age in both normal and SV40-transformed human fibroblasts. Oncogene 1995, 10:835-840.
    • (1995) Oncogene , vol.10 , pp. 835-840
    • Tahara, H.1    Sato, E.2    Noda, A.3    Ide, T.4
  • 97
    • 0033732110 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes
    • Toussaint O., Medrano E.E., von Zglinicki T. Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes. Experimental Gerontology 2000, 35:927-945.
    • (2000) Experimental Gerontology , vol.35 , pp. 927-945
    • Toussaint, O.1    Medrano, E.E.2    von Zglinicki, T.3
  • 100
    • 50649101095 scopus 로고    scopus 로고
    • Puzzles, promises and a cure for aging
    • Vijg J., Campisi J. Puzzles, promises and a cure for aging. Nature 2008, 454:1065-1071.
    • (2008) Nature , vol.454 , pp. 1065-1071
    • Vijg, J.1    Campisi, J.2
  • 102
    • 0029563013 scopus 로고
    • Lipofuscin accumulation and aging of fibroblasts
    • von Zglinicki T., Nilsson E., Döcke W.D., Brunk U.T. Lipofuscin accumulation and aging of fibroblasts. Gerontology 1995, 41(Suppl. 2):95-108.
    • (1995) Gerontology , vol.41 , Issue.SUPPL. 2 , pp. 95-108
    • von Zglinicki, T.1    Nilsson, E.2    Döcke, W.D.3    Brunk, U.T.4
  • 104
    • 0021179316 scopus 로고
    • Increased organization of cytoskeleton accompanying the aging of human fibroblasts in vitro
    • Wang E., Gundersen D. Increased organization of cytoskeleton accompanying the aging of human fibroblasts in vitro. Experimental Cell Research 1984, 154:191-202.
    • (1984) Experimental Cell Research , vol.154 , pp. 191-202
    • Wang, E.1    Gundersen, D.2
  • 107
    • 0030612349 scopus 로고    scopus 로고
    • Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging
    • Zindy F., Quelle D.E., Roussel M.F., Sherr C.J. Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging. Oncogene 1997, 15:203-211.
    • (1997) Oncogene , vol.15 , pp. 203-211
    • Zindy, F.1    Quelle, D.E.2    Roussel, M.F.3    Sherr, C.J.4


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