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Volumn 3, Issue 1, 2011, Pages 1-14

TGF-β Biology in mammary development and breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 84863866563     PISSN: None     EISSN: 19430264     Source Type: Journal    
DOI: 10.1101/cshperspect.a003277     Document Type: Article
Times cited : (197)

References (110)
  • 1
    • 0031891656 scopus 로고    scopus 로고
    • Cell-associated activation of latent transforming growth factor-β by calpain
    • Abe M, Oda N, Sato Y. 1998. Cell-associated activation of latent transforming growth factor-β by calpain. J Cell Physiol 174: 186-193.
    • (1998) J Cell Physiol , vol.174 , pp. 186-193
    • Abe, M.1    Oda, N.2    Sato, Y.3
  • 2
    • 0036301212 scopus 로고    scopus 로고
    • Impaired liver regeneration in mice by lipopolysaccharide via TNF-[α]/kallikreinmediated activation of latent TGF-[β]
    • Akita K, Okuno M, Enya M, Imai S, Moriwaki H, Kawada N, Suzuki Y, Kojima S. 2002. Impaired liver regeneration in mice by lipopolysaccharide via TNF-[α]/kallikreinmediated activation of latent TGF-[β]. Gastroenterology 123: 352-364.
    • (2002) Gastroenterology , vol.123 , pp. 352-364
    • Akita, K.1    Okuno, M.2    Enya, M.3    Imai, S.4    Moriwaki, H.5    Kawada, N.6    Suzuki, Y.7    Kojima, S.8
  • 4
    • 0027193827 scopus 로고
    • Transforming growth factor b as a predictor of liver and lung fibrosis after autologous bone marrow transplantation for advanced breast cancer
    • Anscher MS, Peters WP, Reisenbichler H, Petros WP, Jirtle RL. 1993. Transforming growth factor b as a predictor of liver and lung fibrosis after autologous bone marrow transplantation for advanced breast cancer. New England J Med 328: 1592-1598.
    • (1993) New England J Med , vol.328 , pp. 1592-1598
    • Anscher, M.S.1    Peters, W.P.2    Reisenbichler, H.3    Petros, W.P.4    Jirtle, R.L.5
  • 5
    • 0029736871 scopus 로고    scopus 로고
    • Redox-mediated activation of latent transforming growth factor-β1
    • Barcellos-Hoff MH, Dix TA. 1996. Redox-mediated activation of latent transforming growth factor-β1. Molec Endocrin 10: 1077-1083.
    • (1996) Molec Endocrin , vol.10 , pp. 1077-1083
    • Barcellos-Hoff, M.H.1    Dix, T.A.2
  • 8
    • 70350231912 scopus 로고    scopus 로고
    • Gain or loss of TGF-β signaling in mammary carcinoma cells can promote metastasis
    • Bierie B, Moses HL. 2009. Gain or loss of TGF-β signaling in mammary carcinoma cells can promote metastasis. Cell Cycle 8: 3319-3327.
    • (2009) Cell Cycle , vol.8 , pp. 3319-3327
    • Bierie, B.1    Moses, H.L.2
  • 10
    • 60849083816 scopus 로고    scopus 로고
    • TGF-β promotes cell death and suppresses lactation during the second stage of mammary involution
    • Bierie B, Gorska AE, Stover DG, Moses HL. 2009. TGF-β promotes cell death and suppresses lactation during the second stage of mammary involution. J Cell Physiol 219: 57-68.
    • (2009) J Cell Physiol , vol.219 , pp. 57-68
    • Bierie, B.1    Gorska, A.E.2    Stover, D.G.3    Moses, H.L.4
  • 12
    • 0031441041 scopus 로고    scopus 로고
    • Transgenic mice overexpressing a dominantnegative mutant type II transforming growth factor b receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimthylbenz-[a]-anthracene
    • Bottinger EP, Jakubczak JL, Haines DC, Bagnall K, Wakefield LM. 1997. Transgenic mice overexpressing a dominantnegative mutant type II transforming growth factor b receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimthylbenz-[a]-anthracene. Cancer Res 57: 5564-5570.
    • (1997) Cancer Res , vol.57 , pp. 5564-5570
    • Bottinger, E.P.1    Jakubczak, J.L.2    Haines, D.C.3    Bagnall, K.4    Wakefield, L.M.5
  • 13
    • 0035953393 scopus 로고    scopus 로고
    • Reducing mammary cancer risk through premature stem cell senescence
    • Boulanger CA, Smith GH. 2001. Reducing mammary cancer risk through premature stem cell senescence. Oncogene 20: 2264-2272.
    • (2001) Oncogene , vol.20 , pp. 2264-2272
    • Boulanger, C.A.1    Smith, G.H.2
  • 14
    • 84981758100 scopus 로고
    • Topography ofDNA synthesis in the mammary gland of the C3H mouse and its control by ovarian hormones: An autoradiographic study
    • Bresciani F. 1968. Topography ofDNA synthesis in the mammary gland of the C3H mouse and its control by ovarian hormones: An autoradiographic study. Cell Tiss Kinet 1: 51-63.
    • (1968) Cell Tiss Kinet , vol.1 , pp. 51-63
    • Bresciani, F.1
  • 16
    • 34247539528 scopus 로고    scopus 로고
    • A tale of two proteins: Differential roles and regulation of Smad2 and Smad3 in TGF-β signaling
    • Brown KA, Pietenpol JA, Moses HL. 2007. A tale of two proteins: Differential roles and regulation of Smad2 and Smad3 in TGF-β signaling. J Cell Biochem 101: 9-33.
    • (2007) J Cell Biochem , vol.101 , pp. 9-33
    • Brown, K.A.1    Pietenpol, J.A.2    Moses, H.L.3
  • 17
    • 0024312217 scopus 로고
    • Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor b 1 precursor
    • Brunner AM, Marquardt H, Malacko AR, Lioubin MN, Purchio AF. 1989. Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor b 1 precursor. J Biol Chem 264: 13660-13664.
    • (1989) J Biol Chem , vol.264 , pp. 13660-13664
    • Brunner, A.M.1    Marquardt, H.2    Malacko, A.R.3    Lioubin, M.N.4    Purchio, A.F.5
  • 19
    • 23744452875 scopus 로고    scopus 로고
    • Loss of TGF-[β] type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-[α]-, MSPand HGF-mediated signaling networks
    • Cheng N, Bhowmick NA, Chytil A, Gorksa AE, Brown KA, Muraoka R, Arteaga CL, Neilson EG, Hayward SW, Moses HL. 2005. Loss of TGF-[β] type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-[α]-, MSPand HGF-mediated signaling networks. Oncogene 24: 5053-5068.
    • (2005) Oncogene , vol.24 , pp. 5053-5068
    • Cheng, N.1    Bhowmick, N.A.2    Chytil, A.3    Gorksa, A.E.4    Brown, K.A.5    Muraoka, R.6    Arteaga, C.L.7    Neilson, E.G.8    Hayward, S.W.9    Moses, H.L.10
  • 21
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS, Anderson E. 1997. Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 57: 4987-4991.
    • (1997) Cancer Res , vol.57 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 22
    • 55849145475 scopus 로고    scopus 로고
    • Transforming growth factor {β}-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth
    • Daly AC, Randall RA, Hill CS. 2008. Transforming growth factor {β}-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth. Mol Cell Biol 28: 6889-6902.
    • (2008) Mol Cell Biol , vol.28 , pp. 6889-6902
    • Daly, A.C.1    Randall, R.A.2    Hill, C.S.3
  • 23
    • 0026776501 scopus 로고
    • Regulation of mammary growth and function by TGF-b
    • Daniel CW, Robinson SD. 1992. Regulation of mammary growth and function by TGF-b. Mol Reprod Dev 32: 145-151.
    • (1992) Mol Reprod Dev , vol.32 , pp. 145-151
    • Daniel, C.W.1    Robinson, S.D.2
  • 24
    • 0023577680 scopus 로고
    • Direct action of 17 β-estradiol on mouse mammary ducts analyzed by sustained release implants and steroid autoradiography
    • Daniel CW, Silberstein GB, Strickland P. 1987. Direct action of 17 β-estradiol on mouse mammary ducts analyzed by sustained release implants and steroid autoradiography. Cancer Res 47: 6052-6057.
    • (1987) Cancer Res , vol.47 , pp. 6052-6057
    • Daniel, C.W.1    Silberstein, G.B.2    Strickland, P.3
  • 25
    • 0024366047 scopus 로고
    • TGF-b1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization
    • Daniel CW, Silberstein GB, Van Horn K, Strickland P, Robinson S. 1989. TGF-b1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization. Develop Biol 135: 20-30.
    • (1989) Develop Biol , vol.135 , pp. 20-30
    • Daniel, C.W.1    Silberstein, G.B.2    van Horn, K.3    Strickland, P.4    Robinson, S.5
  • 26
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-βfamily signalling
    • Derynck R, Zhang YE. 2003. Smad-dependent and Smad-independent pathways in TGF-βfamily signalling. Nature 425: 577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 27
    • 0035918274 scopus 로고    scopus 로고
    • Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
    • Ebisawa T, Fukuchi M, Murakami G, Chiba T, Tanaka K, Imamura T, Miyazono K. 2001. Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J Biol Chem 276: 12477-12480.
    • (2001) J Biol Chem , vol.276 , pp. 12477-12480
    • Ebisawa, T.1    Fukuchi, M.2    Murakami, G.3    Chiba, T.4    Tanaka, K.5    Imamura, T.6    Miyazono, K.7
  • 28
    • 0030770411 scopus 로고    scopus 로고
    • Latent transforming growth factor-b activation in situ: Quantitative and functional evidence following low dose irradiation
    • Ehrhart EJ, Carroll A, Segarini P, Tsang M.L.-S, Barcellos-Hoff MH. 1997. Latent transforming growth factor-b activation in situ: Quantitative and functional evidence following low dose irradiation. FASEB J 11: 991-1002.
    • (1997) FASEB J , vol.11 , pp. 991-1002
    • Ehrhart, E.J.1    Carroll, A.2    Segarini, P.3    Tsang, M.L.-S.4    Barcellos-Hoff, M.H.5
  • 29
    • 70350710119 scopus 로고    scopus 로고
    • Rethinking screening for breast cancer and prostate cancer
    • Esserman L, Shieh Y, Thompson I. 2009. Rethinking screening for breast cancer and prostate cancer. JAMA 302: 1685-1692.
    • (2009) JAMA , vol.302 , pp. 1685-1692
    • Esserman, L.1    Shieh, Y.2    Thompson, I.3
  • 30
    • 25144457206 scopus 로고    scopus 로고
    • Proliferation of estrogen receptor-α-positive mammary epithelial cells is restrained by transforming growth factor-β 1 in adult mice
    • Ewan KBR, Oketch-Rabah HA, Ravani SA, Shyamala G, Moses HL, Barcellos-Hoff MH. 2005. Proliferation of estrogen receptor-α-positive mammary epithelial cells is restrained by transforming growth factor-β 1 in adult mice. Am J Pathol 167: 409-417.
    • (2005) Am J Pathol , vol.167 , pp. 409-417
    • Ewan, K.B.R.1    Oketch-Rabah, H.A.2    Ravani, S.A.3    Shyamala, G.4    Moses, H.L.5    Barcellos-Hoff, M.H.6
  • 31
    • 0036081239 scopus 로고    scopus 로고
    • Latent TGF-b activation in mammary gland: Regulation by ovarian hormones affects ductal and alveolar proliferation
    • Ewan KB, Shyamala G, Ravani SA, Tang Y, Akhurst RJ, Wakefield L, Barcellos-Hoff MH. 2002. Latent TGF-b activation in mammary gland: Regulation by ovarian hormones affects ductal and alveolar proliferation. Am J Path 160: 2081-2093.
    • (2002) Am J Path , vol.160 , pp. 2081-2093
    • Ewan, K.B.1    Shyamala, G.2    Ravani, S.A.3    Tang, Y.4    Akhurst, R.J.5    Wakefield, L.6    Barcellos-Hoff, M.H.7
  • 32
    • 23044466047 scopus 로고    scopus 로고
    • Specificity and versatility in tgfbeta signaling through Smads
    • Feng XH, Derynck R. 2005. Specificity and versatility in tgfbeta signaling through Smads. Annu Rev Cell Dev Biol 21: 659-693.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 659-693
    • Feng, X.H.1    Derynck, R.2
  • 34
    • 0026535130 scopus 로고
    • Changes in the extracellular matrix of the normal human breast during the menstrual cycle
    • Ferguson JE, Schor AM, Howell A, Ferguson MW. 1992. Changes in the extracellular matrix of the normal human breast during the menstrual cycle. Cell Tissue Res 268: 167-177.
    • (1992) Cell Tissue Res , vol.268 , pp. 167-177
    • Ferguson, J.E.1    Schor, A.M.2    Howell, A.3    Ferguson, M.W.4
  • 35
    • 0027082811 scopus 로고
    • The extracellular regulation of growth factor action
    • Flaumenhaft R, Rifkin DB. 1992. The extracellular regulation of growth factor action. Mol Biol Cell 3: 1057-1065.
    • (1992) Mol Biol Cell , vol.3 , pp. 1057-1065
    • Flaumenhaft, R.1    Rifkin, D.B.2
  • 36
    • 16844373628 scopus 로고    scopus 로고
    • Effect of conditional knockout of the type II TGF-β receptor gene in mammary epithelia on mammary gland development and polyomavirus middle Tantigen induced tumor formation and metastasis
    • Forrester E, Chytil A, Bierie B, Aakre M, Gorska AE, Sharif-Afshar AR, Muller WJ, Moses HL. 2005. Effect of conditional knockout of the type II TGF-β receptor gene in mammary epithelia on mammary gland development and polyomavirus middle Tantigen induced tumor formation and metastasis. Cancer Res 65: 2296-2302.
    • (2005) Cancer Res , vol.65 , pp. 2296-2302
    • Forrester, E.1    Chytil, A.2    Bierie, B.3    Aakre, M.4    Gorska, A.E.5    Sharif-Afshar, A.R.6    Muller, W.J.7    Moses, H.L.8
  • 37
    • 0027421280 scopus 로고
    • Resistance to inhibition of cell growth by transforming growth factor-b and its role in oncogenesis
    • Fynan TM, Reiss M. 1993. Resistance to inhibition of cell growth by transforming growth factor-b and its role in oncogenesis. Critical Rev Oncogen 4: 493-540.
    • (1993) Critical Rev Oncogen , vol.4 , pp. 493-540
    • Fynan, T.M.1    Reiss, M.2
  • 38
    • 33751320565 scopus 로고    scopus 로고
    • Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-β type I receptor kinase in vivo
    • Ge R, Rajeev V, Ray P, Lattime E, Rittling S, Medicherla S, Protter A, Murphy A, Chakravarty J, Dugar S, et al. 2006. Inhibition of growth and metastasis of mouse mammary carcinoma by selective inhibitor of transforming growth factor-β type I receptor kinase in vivo. Clin Cancer Res 12: 4315-4330.
    • (2006) Clin Cancer Res , vol.12 , pp. 4315-4330
    • Ge, R.1    Rajeev, V.2    Ray, P.3    Lattime, E.4    Rittling, S.5    Medicherla, S.6    Protter, A.7    Murphy, A.8    Chakravarty, J.9    Dugar, S.10
  • 40
    • 0026091746 scopus 로고
    • Localization of basic fibroblast growth factor and transforming growth factor β1 in the human mammary gland
    • Gomm JJ, Smithe J, Ryall GK, Baillie R, Turnbull L, Coombes RC. 1991. Localization of basic fibroblast growth factor and transforming growth factor β1 in the human mammary gland. Cancer Res 51: 4685-4692.
    • (1991) Cancer Res , vol.51 , pp. 4685-4692
    • Gomm, J.J.1    Smithe, J.2    Ryall, G.K.3    Baillie, R.4    Turnbull, L.5    Coombes, R.C.6
  • 41
    • 0141537150 scopus 로고    scopus 로고
    • Transgenic mice expressing a dominantnegative mutant type II transforming growth factor-β receptor exhibit impaired mammary development and enhanced mammary tumor formation
    • Gorska AE, Jensen RA, Shyr Y, Aakre ME, Bhowmick NA, Moses HL. 2003. Transgenic mice expressing a dominantnegative mutant type II transforming growth factor-β receptor exhibit impaired mammary development and enhanced mammary tumor formation. Am J Pathol 163: 1539-1549.
    • (2003) Am J Pathol , vol.163 , pp. 1539-1549
    • Gorska, A.E.1    Jensen, R.A.2    Shyr, Y.3    Aakre, M.E.4    Bhowmick, N.A.5    Moses, H.L.6
  • 45
    • 55449107515 scopus 로고    scopus 로고
    • Regulation of TGF-β family signaling by E3 ubiquitin ligases
    • Inoue Y, Imamura T. 2008. Regulation of TGF-β family signaling by E3 ubiquitin ligases. Cancer Sci 99: 2107-2112.
    • (2008) Cancer Sci , vol.99 , pp. 2107-2112
    • Inoue, Y.1    Imamura, T.2
  • 46
    • 0027286692 scopus 로고
    • Targeting expression of a transforming growth factor β1 transgene to the pregnant mammary gland inhibits alveolar development and lactation
    • Jhappan C, Geiser AG, Kordon EC, Bagheri D, Hennighausen L, Roberts AB, Smith GH, Merlino G. 1993. Targeting expression of a transforming growth factor β1 transgene to the pregnant mammary gland inhibits alveolar development and lactation. EMBO J 12: 1835-1845.
    • (1993) EMBO J , vol.12 , pp. 1835-1845
    • Jhappan, C.1    Geiser, A.G.2    Kordon, E.C.3    Bagheri, D.4    Hennighausen, L.5    Roberts, A.B.6    Smith, G.H.7    Merlino, G.8
  • 48
    • 0032910954 scopus 로고    scopus 로고
    • Overexpression of a kinase-deficient transforming growth factor-b type II receptor in mouse mammary stroma results in increased epithelial branching
    • Joseph H, Gorska AE, Sohn P, Moses HL, Serra R. 1999. Overexpression of a kinase-deficient transforming growth factor-b type II receptor in mouse mammary stroma results in increased epithelial branching. Molec Biol Cell 10: 1221-1234.
    • (1999) Molec Biol Cell , vol.10 , pp. 1221-1234
    • Joseph, H.1    Gorska, A.E.2    Sohn, P.3    Moses, H.L.4    Serra, R.5
  • 49
    • 0000031048 scopus 로고    scopus 로고
    • Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer
    • Kang SH, Bang YJ, Im YH, Yang HK, Lee DA, Lee HY, Lee HS, Kim NK, Kim SJ. 1999. Transcriptional repression of the transforming growth factor-β type I receptor gene by DNA methylation results in the development of TGF-β resistance in human gastric cancer. Oncogene 18: 7280-7286.
    • (1999) Oncogene , vol.18 , pp. 7280-7286
    • Kang, S.H.1    Bang, Y.J.2    Im, Y.H.3    Yang, H.K.4    Lee, D.A.5    Lee, H.Y.6    Lee, H.S.7    Kim, N.K.8    Kim, S.J.9
  • 50
    • 0034517389 scopus 로고    scopus 로고
    • Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF[β] receptor for degradation
    • Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL. 2000. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF[β] receptor for degradation. Mol Cell 6: 1365-1375.
    • (2000) Mol Cell , vol.6 , pp. 1365-1375
    • Kavsak, P.1    Rasmussen, R.K.2    Causing, C.G.3    Bonni, S.4    Zhu, H.5    Thomsen, G.H.6    Wrana, J.L.7
  • 52
    • 0034027480 scopus 로고    scopus 로고
    • Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis
    • Kim SJ, Im YH, Markowitz SD, Bang YJ. 2000. Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis. Cytokine Growth Factor Rev 11: 159-168.
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 159-168
    • Kim, S.J.1    Im, Y.H.2    Markowitz, S.D.3    Bang, Y.J.4
  • 54
    • 0023625418 scopus 로고
    • Evidence that transforming growth factor-b is a hormonally regulated negative growth factor in human breast cancer cells
    • Knabbe C, Lippman ME, Wakefield LM, Flanders KC, Dasid A, Derynck R, Dickson RB. 1987. Evidence that transforming growth factor-b is a hormonally regulated negative growth factor in human breast cancer cells. Cell 48: 417-428.
    • (1987) Cell , vol.48 , pp. 417-428
    • Knabbe, C.1    Lippman, M.E.2    Wakefield, L.M.3    Flanders, K.C.4    Dasid, A.5    Derynck, R.6    Dickson, R.B.7
  • 55
    • 0028986768 scopus 로고
    • Ectopic TGF β 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population
    • Kordon EC, McKnight RA, Jhappan C, Hennighausen L, Merlino G, Smith GH. 1995. Ectopic TGF β 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population. Dev Biol 168: 47-61.
    • (1995) Dev Biol , vol.168 , pp. 47-61
    • Kordon, E.C.1    McKnight, R.A.2    Jhappan, C.3    Hennighausen, L.4    Merlino, G.5    Smith, G.H.6
  • 58
    • 30944444113 scopus 로고    scopus 로고
    • Alterations in components of the TGF-β superfamily signaling pathways in human cancer
    • Levy L, Hill CS. 2006. Alterations in components of the TGF-β superfamily signaling pathways in human cancer. Cytokine Growth Factor Rev 17: 41-58.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 41-58
    • Levy, L.1    Hill, C.S.2
  • 60
    • 58749089988 scopus 로고    scopus 로고
    • TGF[β]-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGF[β] switch
    • Liu IM, Schilling SH, Knouse KA, Choy L, Derynck R, Wang X-F. 2009. TGF[β]-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGF[β] switch. EMBO J 28: 88-98.
    • (2009) EMBO J , vol.28 , pp. 88-98
    • Liu, I.M.1    Schilling, S.H.2    Knouse, K.A.3    Choy, L.4    Derynck, R.5    Wang, X.-F.6
  • 61
    • 0033200361 scopus 로고    scopus 로고
    • The Ski oncoprotein interacts with the Smad proteins to repress TGF-β signaling
    • Luo K, Stroschein SL, Wang W, Chen D, Martens E, Zhou S, Zhou Q. 1999. The Ski oncoprotein interacts with the Smad proteins to repress TGF-β signaling. Genes Dev 13: 2196-2206.
    • (1999) Genes Dev , vol.13 , pp. 2196-2206
    • Luo, K.1    Stroschein, S.L.2    Wang, W.3    Chen, D.4    Martens, E.5    Zhou, S.6    Zhou, Q.7
  • 63
    • 0023916551 scopus 로고
    • Proteolytic activation of latent transforming growth factor-b from fibroblast conditioned medium
    • Lyons RM, Keski-Oja J, Moses HL. 1988. Proteolytic activation of latent transforming growth factor-b from fibroblast conditioned medium. J Cell Biol 106: 1659-1665.
    • (1988) J Cell Biol , vol.106 , pp. 1659-1665
    • Lyons, R.M.1    Keski-Oja, J.2    Moses, H.L.3
  • 64
    • 0025650608 scopus 로고
    • Effect of transforming growth factor-β1 on proliferation and death of rat prostatic cells
    • Martikainen P, Kyprianou N, Isaacs JT. 1990. Effect of transforming growth factor-β1 on proliferation and death of rat prostatic cells. Endocrinology 127: 2963-2968.
    • (1990) Endocrinology , vol.127 , pp. 2963-2968
    • Martikainen, P.1    Kyprianou, N.2    Isaacs, J.T.3
  • 65
    • 47549090432 scopus 로고    scopus 로고
    • TGF[β] in Cancer
    • Massagué J. 2008. TGF[β] in Cancer. Cell 134: 215-230.
    • (2008) Cell , vol.134 , pp. 215-230
    • Massagué, J.1
  • 66
  • 68
    • 0024539847 scopus 로고
    • Role for carbohydrate structures in TGF-b1 latency
    • Miyazono K, Heldin C-H. 1989. Role for carbohydrate structures in TGF-b1 latency. Nature 338: 158-160.
    • (1989) Nature , vol.338 , pp. 158-160
    • Miyazono, K.1    Heldin, C.-H.2
  • 69
    • 77349121470 scopus 로고    scopus 로고
    • The discovery of TGF-ß: A historical perspective
    • In, (ed. K.R.A.M. Derynck),. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • Moses HL, Roberts AB. 2008. The discovery of TGF-ß: A historical perspective. In The TGF-ß family (ed. K.R.A.M. Derynck), pp. 1-28. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (2008) The TGF-ß family , pp. 1-28
    • Moses, H.L.1    Roberts, A.B.2
  • 70
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
    • Moustakas A, Heldin CH. 2007. Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci 98: 1512-1520.
    • (2007) Cancer Sci , vol.98 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.H.2
  • 71
    • 0033524949 scopus 로고    scopus 로고
    • The integrin α v β 6 binds and activates latent TGF β 1: A mechanism for regulating pulmonary inflammation and fibrosis
    • Munger J, Huang X, Kawakatsu H, Griffiths M, Dalton S, Wu J, Pittet J, Kaminski N, Garat C, Matthay M, et al. 1999. The integrin α v β 6 binds and activates latent TGF β 1: A mechanism for regulating pulmonary inflammation and fibrosis. Cell 96: 319-328.
    • (1999) Cell , vol.96 , pp. 319-328
    • Munger, J.1    Huang, X.2    Kawakatsu, H.3    Griffiths, M.4    Dalton, S.5    Wu, J.6    Pittet, J.7    Kaminski, N.8    Garat, C.9    Matthay, M.10
  • 73
    • 33745050200 scopus 로고    scopus 로고
    • Activated type I TGF[β] receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression
    • doi: 10.1038/sj.onc.1208964:1-16
    • Muraoka-Cook RS, Shin I, Yi JY, Easterly E, Barcellos-Hoff MH, Yingling JM, Zent R, Arteaga CL. 2005. Activated type I TGF[β] receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression. Oncogene doi: 10.1038/sj.onc.1208964:1-16.
    • (2005) Oncogene
    • Muraoka-Cook, R.S.1    Shin, I.2    Yi, J.Y.3    Easterly, E.4    Barcellos-Hoff, M.H.5    Yingling, J.M.6    Zent, R.7    Arteaga, C.L.8
  • 75
    • 33749992857 scopus 로고    scopus 로고
    • Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures
    • Nelson CM, VanDuijn MM, Inman JL, Fletcher DA, Bissell MJ. 2006. Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science 314: 298-300.
    • (2006) Science , vol.314 , pp. 298-300
    • Nelson, C.M.1    VanDuijn, M.M.2    Inman, J.L.3    Fletcher, D.A.4    Bissell, M.J.5
  • 76
    • 0025179952 scopus 로고
    • Growth regulatory activities of endothelial extracellular matrix mediation by transforming growth factor-b
    • Newton LK, Yung WKA, Pettigrew LC, Steck PA. 1990. Growth regulatory activities of endothelial extracellular matrix mediation by transforming growth factor-b. Expt Cell Res 190: 127-132.
    • (1990) Expt Cell Res , vol.190 , pp. 127-132
    • Newton, L.K.1    Yung, W.K.A.2    Pettigrew, L.C.3    Steck, P.A.4
  • 77
    • 0033858512 scopus 로고    scopus 로고
    • Transforming growth factor b3 induces cell death during the first stage of mammary gland involution
    • Nguyen AV, Pollard JW. 2000. Transforming growth factor b3 induces cell death during the first stage of mammary gland involution. Development 127: 3107-3118.
    • (2000) Development , vol.127 , pp. 3107-3118
    • Nguyen, A.V.1    Pollard, J.W.2
  • 78
  • 79
    • 0037092964 scopus 로고    scopus 로고
    • Transforming growth factor {β} signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition
    • Parekh TV, Gama P, Wen X, Demopoulos R, Munger JS, Carcangiu M-L, Reiss M, Gold LI. 2002. Transforming growth factor {β} signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition. Cancer Res 62: 2778-2790.
    • (2002) Cancer Res , vol.62 , pp. 2778-2790
    • Parekh, T.V.1    Gama, P.2    Wen, X.3    Demopoulos, R.4    Munger, J.S.5    Carcangiu, M-L.6    Reiss, M.7    Gold, L.I.8
  • 80
    • 0024515459 scopus 로고
    • Enhanced jun gene expression is an early genomic response to transforming growth factor β stimulation
    • Pertovaara L, Sistonen L, Bos TJ, Vogt PK, Keski OJ, Alitalo K. 1989. Enhanced jun gene expression is an early genomic response to transforming growth factor β stimulation. Mol Cell Biol 9: 1255-1262.
    • (1989) Mol Cell Biol , vol.9 , pp. 1255-1262
    • Pertovaara, L.1    Sistonen, L.2    Bos, T.J.3    Vogt, P.K.4    Keski, O.J.5    Alitalo, K.6
  • 84
    • 0027498034 scopus 로고
    • TGFb suppresses casein synthesis in mouse mammary explants and may play a role in controlling milk levels
    • Robinson SD, Roberts AB, Daniel CW. 1993. TGFb suppresses casein synthesis in mouse mammary explants and may play a role in controlling milk levels. J Cell Biol 120: 245-251.
    • (1993) J Cell Biol , vol.120 , pp. 245-251
    • Robinson, S.D.1    Roberts, A.B.2    Daniel, C.W.3
  • 85
    • 0026318253 scopus 로고
    • Coordinated regulation of apoptosis and cell proliferation by transforming growth factor b 1 in cultured uterine epithelial cells
    • Rotello RJ, Lieberman RC, Purchio AF, Gerschenson LE. 1991. Coordinated regulation of apoptosis and cell proliferation by transforming growth factor b 1 in cultured uterine epithelial cells. Proc Natl Acad Sci 88: 3412-3415.
    • (1991) Proc Natl Acad Sci , vol.88 , pp. 3412-3415
    • Rotello, R.J.1    Lieberman, R.C.2    Purchio, A.F.3    Gerschenson, L.E.4
  • 86
    • 0029861191 scopus 로고    scopus 로고
    • Influenza virus neuraminidase activates latent transforming growth factor beta
    • Schultz-Cherry S, Hinshaw V. 1996. Influenza virus neuraminidase activates latent transforming growth factor beta. J Virol 70: 8624-8629.
    • (1996) J Virol , vol.70 , pp. 8624-8629
    • Schultz-Cherry, S.1    Hinshaw, V.2
  • 87
    • 0027305971 scopus 로고
    • Thrombospondin causes activation of latent transforming growth factor-b secreted by endothelial cells by a novel mechanism
    • Schultz-Cherry S, Murphy-Ullrich JE. 1993. Thrombospondin causes activation of latent transforming growth factor-b secreted by endothelial cells by a novel mechanism. J Cell Biol 122: 923-932.
    • (1993) J Cell Biol , vol.122 , pp. 923-932
    • Schultz-Cherry, S.1    Murphy-Ullrich, J.E.2
  • 88
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Shi Y, Massague J. 2003. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 90
    • 0037816160 scopus 로고    scopus 로고
    • Transforming growth factor β signaling impairs Neuinduced mammary tumorigenesis while promoting pulmonary metastasis
    • Siegel PM, ShuW, Cardiff RD, Muller WJ, Massague J. 2003. Transforming growth factor β signaling impairs Neuinduced mammary tumorigenesis while promoting pulmonary metastasis. Proc Natl Acad Sci U S A 100: 8430-8435.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8430-8435
    • Siegel, P.M.1    Shu, W.2    Cardiff, R.D.3    Muller, W.J.4    Massague, J.5
  • 91
    • 0023251107 scopus 로고
    • Reversible inhibition of mammary gland growth by transforming growth factor-ß
    • Silberstein GB, Daniel CW. 1987. Reversible inhibition of mammary gland growth by transforming growth factor-ß. Science 237: 291-293.
    • (1987) Science , vol.237 , pp. 291-293
    • Silberstein, G.B.1    Daniel, C.W.2
  • 92
    • 0026661308 scopus 로고
    • Regulation of mammary morphogenesis: Evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-β1
    • Silberstein GB, Flanders KC, Roberts AB, Daniel CW. 1992. Regulation of mammary morphogenesis: Evidence for extracellular matrix-mediated inhibition of ductal budding by transforming growth factor-β1. Dev Biol 152: 354-362.
    • (1992) Dev Biol , vol.152 , pp. 354-362
    • Silberstein, G.B.1    Flanders, K.C.2    Roberts, A.B.3    Daniel, C.W.4
  • 93
    • 0025302390 scopus 로고
    • Epithelium-dependent extracellular matrix synthesis in transforming growth factor-β1-growth-inhibited mouse mammary gland
    • Silberstein GB, Strickland P, Coleman S, Daniel CW. 1990. Epithelium-dependent extracellular matrix synthesis in transforming growth factor-β1-growth-inhibited mouse mammary gland. J Cell Biol 110: 2209-2219.
    • (1990) J Cell Biol , vol.110 , pp. 2209-2219
    • Silberstein, G.B.1    Strickland, P.2    Coleman, S.3    Daniel, C.W.4
  • 94
    • 77449109233 scopus 로고    scopus 로고
    • Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice
    • Simian M, Bissell M, Barcellos-Hoff M, Shyamala G. 2009. Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice. Breast Cancer Res 11: R72.
    • (2009) Breast Cancer Res , vol.11
    • Simian, M.1    Bissell, M.2    Barcellos-Hoff, M.3    Shyamala, G.4
  • 95
    • 0029664503 scopus 로고    scopus 로고
    • TGF-b1 induces morphogenesis of branching cords by cloned mammary epithelial cells at subpicomolar concentrations
    • Soriano JV, Orci L, Montesano R. 1996. TGF-b1 induces morphogenesis of branching cords by cloned mammary epithelial cells at subpicomolar concentrations. Biochem Biophys Res Comm 220: 879-885.
    • (1996) Biochem Biophys Res Comm , vol.220 , pp. 879-885
    • Soriano, J.V.1    Orci, L.2    Montesano, R.3
  • 96
    • 0027535320 scopus 로고
    • TGF-b induction of extracellular matrix associated proteins in normal and transformed human mammary epithelial cells in culture is independent of growth effects
    • Stampfer MR, Yaswen P, Alhadeff M, Hosoda J. 1993. TGF-b induction of extracellular matrix associated proteins in normal and transformed human mammary epithelial cells in culture is independent of growth effects. J Cell Physiol 155: 210-221.
    • (1993) J Cell Physiol , vol.155 , pp. 210-221
    • Stampfer, M.R.1    Yaswen, P.2    Alhadeff, M.3    Hosoda, J.4
  • 97
    • 0026773069 scopus 로고
    • Apoptotic cell death and tissue remodeling during mouse mammary gland involution
    • Strange R, Li F, Saurer S, Burkhardt A, Friis RR. 1992. Apoptotic cell death and tissue remodeling during mouse mammary gland involution. Development (Camb) 115: 49-58.
    • (1992) Development (Camb) , vol.115 , pp. 49-58
    • Strange, R.1    Li, F.2    Saurer, S.3    Burkhardt, A.4    Friis, R.R.5
  • 99
    • 0033595704 scopus 로고    scopus 로고
    • Negative feedback regulation of TGF-signaling by the SnoN Oncoprotein
    • Stroschein SL, Wang W, Zhou S, Zhou Q, Luo K. 1999. Negative feedback regulation of TGF-signaling by the SnoN Oncoprotein. Science 286: 771-774.
    • (1999) Science , vol.286 , pp. 771-774
    • Stroschein, S.L.1    Wang, W.2    Zhou, S.3    Zhou, Q.4    Luo, K.5
  • 100
    • 0028956737 scopus 로고
    • Human mast cell chymase and leukocyte elastase release latent transforming growth factor-1 from the extracellular matrix of cultured human epithelial and endothelial cells
    • Taipale J, Lohi J, Saarinen J, Kovanen PT, Keski-Oja J. 1995. Human mast cell chymase and leukocyte elastase release latent transforming growth factor-1 from the extracellular matrix of cultured human epithelial and endothelial cells. J Biol Chem 270: 4689-4696.
    • (1995) J Biol Chem , vol.270 , pp. 4689-4696
    • Taipale, J.1    Lohi, J.2    Saarinen, J.3    Kovanen, P.T.4    Keski-Oja, J.5
  • 101
    • 67349091089 scopus 로고    scopus 로고
    • Transforming growth factor-β signaling: Emerging stem cell target in metastatic breast cancer?
    • Tan AR, Alexe G, Reiss M. 2009. Transforming growth factor-β signaling: Emerging stem cell target in metastatic breast cancer? Breast Cancer Res Treat 115: 453-495.
    • (2009) Breast Cancer Res Treat , vol.115 , pp. 453-495
    • Tan, A.R.1    Alexe, G.2    Reiss, M.3
  • 102
    • 62349129614 scopus 로고    scopus 로고
    • Induction of p16ink4a and p19ARF by TGF1 contributes to growth arrest and senescence response in mouse keratinocytes
    • Vijayachandra K, Higgins W, Lee J, Glick A. 2009. Induction of p16ink4a and p19ARF by TGF1 contributes to growth arrest and senescence response in mouse keratinocytes. Mol Carcinog 48: 181-186.
    • (2009) Mol Carcinog , vol.48 , pp. 181-186
    • Vijayachandra, K.1    Higgins, W.2    Lee, J.3    Glick, A.4
  • 104
    • 0030913101 scopus 로고    scopus 로고
    • Extracellular matrix regulates ovarian hormone-dependent proliferation of mouse mammary epithelial cells
    • Xie J, Haslam SZ. 1997. Extracellular matrix regulates ovarian hormone-dependent proliferation of mouse mammary epithelial cells. Endocrinology 138: 2466-2473.
    • (1997) Endocrinology , vol.138 , pp. 2466-2473
    • Xie, J.1    Haslam, S.Z.2
  • 105
    • 0037081179 scopus 로고    scopus 로고
    • Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: Atissue microarray study
    • Xie W, Mertens JC, Reiss DJ, Rimm DL, Camp RL, Haffty BG, Reiss M. 2002. Alterations of Smad signaling in human breast carcinoma are associated with poor outcome: Atissue microarray study. Cancer Res 62: 497-505.
    • (2002) Cancer Res , vol.62 , pp. 497-505
    • Xie, W.1    Mertens, J.C.2    Reiss, D.J.3    Rimm, D.L.4    Camp, R.L.5    Haffty, B.G.6    Reiss, M.7
  • 106
  • 109
    • 10444261212 scopus 로고    scopus 로고
    • Development of TGF-β signalling inhibitors for cancer therapy
    • Yingling JM, Blanchard KL, Sawyer JS. 2004. Development of TGF-β signalling inhibitors for cancer therapy. Nat Rev Drug Discov 3: 1011-1022.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 1011-1022
    • Yingling, J.M.1    Blanchard, K.L.2    Sawyer, J.S.3
  • 110
    • 0034650486 scopus 로고    scopus 로고
    • Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis
    • Yu Q, Stamenkovic I. 2000. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-β and promotes tumor invasion and angiogenesis. Genes Dev 14: 163-176.
    • (2000) Genes Dev , vol.14 , pp. 163-176
    • Yu, Q.1    Stamenkovic, I.2


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