Induction of p16ink4a and p19ARF by TGFβ1 contributes to growth arrest and senescence response in mouse keratinocytes

Molecular Carcinogenesis

Volumn 48, Issue 3, 2009, Pages 181-186

  Vijayachandra, Kinnimulki ^a   Higgins, William ^b   Lee, Jessica ^a   Glick, Adam ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Keratinocyte; Mouse; Senescence; TGF 1; Tumor suppressor

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; MESSENGER RNA; P19 ARF PROTEIN; PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; BETAIG H3 PROTEIN; BETAIG-H3 PROTEIN; CDKN2A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; SCLEROPROTEIN; SMAD2 PROTEIN; SMAD2 PROTEIN, MOUSE; SMAD3 PROTEIN, MOUSE; SMAD4 PROTEIN; SMAD4 PROTEIN, MOUSE; SMAD7 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CDKN2A GENE; CELL CYCLE ARREST; CONTROLLED STUDY; EPIDERMIS CELL; GENE; GENE EXPRESSION; GENE LOCUS; GROWTH DISORDER; KERATINOCYTE; MOUSE; NEWBORN; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; ADENOVIRUS; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CELL AGING; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; EPIDERMIS; GENETICS; METABOLISM; MOUSE MUTANT; ONCOGENE RAS; PHYSIOLOGY; VIRUS CELL TRANSFORMATION;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; CELL AGING; CELL CYCLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION, VIRAL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EPIDERMIS; EXTRACELLULAR MATRIX PROTEINS; GENES, RAS; KERATINOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 62349129614     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20472     Document Type: Article

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