Transforming growth factor β signaling impairs neu-induced mammary tumorigenesis while promoting pulmonary metastasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 14, 2003, Pages 8430-8435

  Siegel, Peter M ^a   Shu, Weiping ^a   Cardiff, Robert D ^b   Muller, William J ^c   Massagué, Joan ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BREAST CARCINOGENESIS; CANCER INHIBITION; CONTROLLED STUDY; FEMALE; GENE FUNCTION; LUNG METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE NEU; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR PROMOTION; TUMOR SUPPRESSOR GENE;

ACTIVIN RECEPTORS, TYPE I; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOPTOSIS; DROSOPHILA PROTEINS; FEMALE; GENES, DOMINANT; GENES, ERBB-2; GRB2 ADAPTOR PROTEIN; HUMANS; LACTATION; LIGASES; LUNG NEOPLASMS; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; MITOTIC INDEX; NEOPLASM PROTEINS; NERVE TISSUE PROTEINS; PREGNANCY; PROTEINS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; TUMOR CELLS, CULTURED; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; MOUSE MAMMARY TUMOR VIRUS; MUS MUSCULUS;

EID: 0037816160     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0932636100     Document Type: Article

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