메뉴 건너뛰기




Volumn 22, Issue 7, 2012, Pages 1197-1211

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN; LGALS4 PROTEIN; MESSENGER RNA; PROTEIN; PROTEIN KINASE LKB1; RAS PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84863550037     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.132662.111     Document Type: Article
Times cited : (432)

References (158)
  • 1
    • 79955768157 scopus 로고    scopus 로고
    • DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast carcinogenesis
    • Acosta D, Suzuki M, Connolly D, Thompson RF, Fazzari MJ, Greally JM, Montagna C. 2011. DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast carcinogenesis. Mamm Genome 22: 249-259.
    • (2011) Mamm Genome , vol.22 , pp. 249-259
    • Acosta, D.1    Suzuki, M.2    Connolly, D.3    Thompson, R.F.4    Fazzari, M.J.5    Greally, J.M.6    Montagna, C.7
  • 7
    • 4544250024 scopus 로고    scopus 로고
    • Gene-promoter hypermethylation as a biomarker in lung cancer
    • Belinsky SA. 2004. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 4: 707-717.
    • (2004) Nat Rev Cancer , vol.4 , pp. 707-717
    • Belinsky, S.A.1
  • 9
    • 0032519580 scopus 로고    scopus 로고
    • Characterization of MAST9/Hevin, a SPARC-like protein, that is down-regulated in non-small cell lung cancer
    • Bendik I, Schraml P, Lludwig CU. 1998. Characterization of MAST9/Hevin, a SPARC-like protein, that is down-regulated in non-small cell lung cancer. Cancer Res 58: 626-629.
    • (1998) Cancer Res , vol.58 , pp. 626-629
    • Bendik, I.1    Schraml, P.2    Lludwig, C.U.3
  • 12
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin MP, Goncharov TM, Goltsev YV, Wallach D. 1996. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell 85: 803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 13
    • 79953706343 scopus 로고    scopus 로고
    • Tobacco-smoking-related differential DNA methylation: 27K discovery and replication
    • Breitling LP, Yang R, Korn B, Burwinkel B, Brenner H. 2011. Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. Am J Hum Genet 88: 450-457.
    • (2011) Am J Hum Genet , vol.88 , pp. 450-457
    • Breitling, L.P.1    Yang, R.2    Korn, B.3    Burwinkel, B.4    Brenner, H.5
  • 14
    • 79251567720 scopus 로고    scopus 로고
    • DNA methylation of the first exon is tightly linked to transcriptional silencing
    • doi: 10.1371/journal.pone.0014524
    • Brenet F, Moh M, Funk P, Feierstein E, Viale AJ, Socci ND, Scandura JM. 2011. DNA methylation of the first exon is tightly linked to transcriptional silencing. PLoS ONE 6: e14524. doi: 10.1371/journal.pone.0014524.
    • (2011) PLoS ONE , vol.6
    • Brenet, F.1    Moh, M.2    Funk, P.3    Feierstein, E.4    Viale, A.J.5    Socci, N.D.6    Scandura, J.M.7
  • 17
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. 2011. Integrated genomic analyses of ovarian carcinoma. Nature 474: 609-615.
    • (2011) Nature , vol.474 , pp. 609-615
  • 21
    • 34547765951 scopus 로고    scopus 로고
    • Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis
    • Clark SJ. 2007. Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis. Hum Mol Genet 16: R88-R95.
    • (2007) Hum Mol Genet , vol.16
    • Clark, S.J.1
  • 25
    • 0347302952 scopus 로고    scopus 로고
    • Cytokines in cancer pathogenesis and cancer therapy
    • Dranoff G. 2004. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 4: 11-22.
    • (2004) Nat Rev Cancer , vol.4 , pp. 11-22
    • Dranoff, G.1
  • 26
    • 46249088370 scopus 로고    scopus 로고
    • Lumi: A pipeline for processing Illumina microarray
    • Du P, Kibbe WA, Lin SM. 2008. lumi: A pipeline for processing Illumina microarray. Bioinformatics 24: 1547-1548.
    • (2008) Bioinformatics , vol.24 , pp. 1547-1548
    • Du, P.1    Kibbe, W.A.2    Lin, S.M.3
  • 27
    • 0038747956 scopus 로고    scopus 로고
    • Relevance of DNA methylation in the management of cancer
    • Esteller M. 2003. Relevance of DNA methylation in the management of cancer. Lancet Oncol 4: 351-358.
    • (2003) Lancet Oncol , vol.4 , pp. 351-358
    • Esteller, M.1
  • 28
    • 0032894125 scopus 로고    scopus 로고
    • Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
    • Esteller M, Sanchez-Cespedes M, Rosell R, Sidransky D, Baylin SB, Herman JG. 1999. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res 59: 67-70.
    • (1999) Cancer Res , vol.59 , pp. 67-70
    • Esteller, M.1    Sanchez-Cespedes, M.2    Rosell, R.3    Sidransky, D.4    Baylin, S.B.5    Herman, J.G.6
  • 29
    • 74849121190 scopus 로고    scopus 로고
    • Sox17, the canonical Wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer
    • Fu DY, Wang ZM, Li C, Wang BL, Shen ZZ, Huang W, Shao ZM. 2010. Sox17, the canonical Wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer. Breast Cancer Res Treat 119: 601-612.
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 601-612
    • Fu, D.Y.1    Wang, Z.M.2    Li, C.3    Wang, B.L.4    Shen, Z.Z.5    Huang, W.6    Shao, Z.M.7
  • 30
    • 0038784365 scopus 로고    scopus 로고
    • SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma
    • Galm O, Yoshikawa H, Esteller M, Osieka R, Herman JG. 2003. SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood 101: 2784-2788.
    • (2003) Blood , vol.101 , pp. 2784-2788
    • Galm, O.1    Yoshikawa, H.2    Esteller, M.3    Osieka, R.4    Herman, J.G.5
  • 32
    • 3242785013 scopus 로고    scopus 로고
    • Prostate derived Ets transcription factor shows better tumor-association than other cancer-associated molecules
    • Ghadersohi A, Odunsi K, Lele S, Collins Y, Greco WR, Winston J, Liang P, Sood AK. 2004. Prostate derived Ets transcription factor shows better tumor-association than other cancer-associated molecules. Oncol Rep 11: 453-458.
    • (2004) Oncol Rep , vol.11 , pp. 453-458
    • Ghadersohi, A.1    Odunsi, K.2    Lele, S.3    Collins, Y.4    Greco, W.R.5    Winston, J.6    Liang, P.7    Sood, A.K.8
  • 33
    • 78650886573 scopus 로고    scopus 로고
    • Rab25 as a tumour suppressor in colon carcinogenesis
    • Goldenring JR, Nam KT. 2011. Rab25 as a tumour suppressor in colon carcinogenesis. Br J Cancer 104: 33-36.
    • (2011) Br J Cancer , vol.104 , pp. 33-36
    • Goldenring, J.R.1    Nam, K.T.2
  • 35
    • 80054880084 scopus 로고    scopus 로고
    • DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter
    • Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G. 2011. DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter. Hum Mol Genet 20: 4299-4310.
    • (2011) Hum Mol Genet , vol.20 , pp. 4299-4310
    • Han, H.1    Cortez, C.C.2    Yang, X.3    Nichols, P.W.4    Jones, P.A.5    Liang, G.6
  • 37
    • 78650508742 scopus 로고    scopus 로고
    • CXCL17 and ICAM2 are associated with a potential antitumor immune response in early intraepithelial stages of human pancreatic carcinogenesis
    • Hiraoka N, Yamazaki-Itoh R, Ino Y, Mizuguchi Y, Yamada T, Hirohashi S, Kanai Y. 2011. CXCL17 and ICAM2 are associated with a potential antitumor immune response in early intraepithelial stages of human pancreatic carcinogenesis. Gastroenterology 140: 310-321.
    • (2011) Gastroenterology , vol.140 , pp. 310-321
    • Hiraoka, N.1    Yamazaki-Itoh, R.2    Ino, Y.3    Mizuguchi, Y.4    Yamada, T.5    Hirohashi, S.6    Kanai, Y.7
  • 39
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. 2009. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 40
    • 74949094228 scopus 로고    scopus 로고
    • Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling
    • Huang J, Zheng DL, Qin FS, Cheng N, Chen H, Wan BB, Wang YP, Xiao HS, Han ZG. 2010. Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling. J Clin Invest 120: 223-241.
    • (2010) J Clin Invest , vol.120 , pp. 223-241
    • Huang, J.1    Zheng, D.L.2    Qin, F.S.3    Cheng, N.4    Chen, H.5    Wan, B.B.6    Wang, Y.P.7    Xiao, H.S.8    Han, Z.G.9
  • 41
    • 79951828866 scopus 로고    scopus 로고
    • Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies
    • Hu-Lowe DD, Chen E, Zhang L, Watson KD, Mancuso P, Lappin P, Wickman G, Chen JH, Wang J, Jiang X, et al. 2011. Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies. Cancer Res 71: 1362-1373.
    • (2011) Cancer Res , vol.71 , pp. 1362-1373
    • Hu-Lowe, D.D.1    Chen, E.2    Zhang, L.3    Watson, K.D.4    Mancuso, P.5    Lappin, P.6    Wickman, G.7    Chen, J.H.8    Wang, J.9    Jiang, X.10
  • 45
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa JP. 2004. CpG island methylator phenotype in cancer. Nat Rev Cancer 4: 988-993.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 48
    • 0037068378 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Jones PA. 2002. DNA methylation and cancer. Oncogene 21: 5358-5360.
    • (2002) Oncogene , vol.21 , pp. 5358-5360
    • Jones, P.A.1
  • 49
  • 51
    • 33847373449 scopus 로고    scopus 로고
    • The role of DNA methylation in the development and progression of lung adenocarcinoma
    • Kerr KM, Galler JS, Hagen JA, Laird PW, Laird-Offringa IA. 2007. The role of DNA methylation in the development and progression of lung adenocarcinoma. Dis Markers 23: 5-30.
    • (2007) Dis Markers , vol.23 , pp. 5-30
    • Kerr, K.M.1    Galler, J.S.2    Hagen, J.A.3    Laird, P.W.4    Laird-Offringa, I.A.5
  • 54
    • 2442614770 scopus 로고    scopus 로고
    • Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo
    • Kobayashi K, Nishioka M, Kohno T, Nakamoto M, Maeshima A, Aoyagi K, Sasaki H, Takenoshita S, Sugimura H, Yokota J. 2004. Identification of genes whose expression is upregulated in lung adenocarcinoma cells in comparison with type II alveolar cells and bronchiolar epithelial cells in vivo. Oncogene 23: 3089-3096.
    • (2004) Oncogene , vol.23 , pp. 3089-3096
    • Kobayashi, K.1    Nishioka, M.2    Kohno, T.3    Nakamoto, M.4    Maeshima, A.5    Aoyagi, K.6    Sasaki, H.7    Takenoshita, S.8    Sugimura, H.9    Yokota, J.10
  • 65
    • 33644877818 scopus 로고    scopus 로고
    • BJ-TSA-9, a novel human tumor-specific gene, has potential as a biomarker of lung cancer
    • Li Y, Dong X, Yin Y, Su Y, Xu Q, Zhang Y, Pang X, Chen W. 2005. BJ-TSA-9, a novel human tumor-specific gene, has potential as a biomarker of lung cancer. Neoplasia 7: 1073-1080.
    • (2005) Neoplasia , vol.7 , pp. 1073-1080
    • Li, Y.1    Dong, X.2    Yin, Y.3    Su, Y.4    Xu, Q.5    Zhang, Y.6    Pang, X.7    Chen, W.8
  • 67
    • 79953749145 scopus 로고    scopus 로고
    • The unholy trinity: Inflammation, cytokines, and STAT3 shape the cancer microenvironment
    • Li N, Grivennikov SI, Karin M. 2011. The unholy trinity: Inflammation, cytokines, and STAT3 shape the cancer microenvironment. Cancer Cell 19: 429-431.
    • (2011) Cancer Cell , vol.19 , pp. 429-431
    • Li, N.1    Grivennikov, S.I.2    Karin, M.3
  • 68
    • 34247491523 scopus 로고    scopus 로고
    • DNA hypermethylation of MAL: A promising diagnostic biomarker for colorectal tumors
    • Lind GE, Ahlquist T, Lothe RA. 2007. DNA hypermethylation of MAL: A promising diagnostic biomarker for colorectal tumors. Gastroenterology 132: 1631-1632.
    • (2007) Gastroenterology , vol.132 , pp. 1631-1632
    • Lind, G.E.1    Ahlquist, T.2    Lothe, R.A.3
  • 71
    • 84860408968 scopus 로고    scopus 로고
    • DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer
    • Lopez-Serra P, Esteller M. 2012. DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer. Oncogene 31: 1609-1622.
    • (2012) Oncogene , vol.31 , pp. 1609-1622
    • Lopez-Serra, P.1    Esteller, M.2
  • 76
    • 79953750307 scopus 로고    scopus 로고
    • Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
    • Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, Berti A, Politi LS, Gentner B, Brown JL, Naldini L, et al. 2011. Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 19: 512-526.
    • (2011) Cancer Cell , vol.19 , pp. 512-526
    • Mazzieri, R.1    Pucci, F.2    Moi, D.3    Zonari, E.4    Ranghetti, A.5    Berti, A.6    Politi, L.S.7    Gentner, B.8    Brown, J.L.9    Naldini, L.10
  • 79
    • 0036893185 scopus 로고    scopus 로고
    • DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines
    • Nishihara H, Maeda M, Oda A, Tsuda M, Sawa H, Nagashima K, Tanaka S. 2002. DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines. Blood 100: 3968-3974.
    • (2002) Blood , vol.100 , pp. 3968-3974
    • Nishihara, H.1    Maeda, M.2    Oda, A.3    Tsuda, M.4    Sawa, H.5    Nagashima, K.6    Tanaka, S.7
  • 80
    • 27144433826 scopus 로고    scopus 로고
    • Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma
    • Niwa Y, Kanda H, Shikauchi Y, Saiura A, Matsubara K, Kitagawa T, Yamamoto J, Kubo T, Yoshikawa H. 2005. Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene 24: 6406-6417.
    • (2005) Oncogene , vol.24 , pp. 6406-6417
    • Niwa, Y.1    Kanda, H.2    Shikauchi, Y.3    Saiura, A.4    Matsubara, K.5    Kitagawa, T.6    Yamamoto, J.7    Kubo, T.8    Yoshikawa, H.9
  • 83
    • 33749069927 scopus 로고    scopus 로고
    • CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
    • Ogino S, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. 2006. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations. J Mol Diagn 8: 582-588.
    • (2006) J Mol Diagn , vol.8 , pp. 582-588
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3    Loda, M.4    Fuchs, C.S.5
  • 85
    • 0035005340 scopus 로고    scopus 로고
    • Reduction in the local expression of complement component 6 (C6) and 7 (C7) mRNAs in oesophageal carcinoma
    • Oka R, Sasagawa T, Ninomiya I, Miwa K, Tanii H, Saijoh K. 2001. Reduction in the local expression of complement component 6 (C6) and 7 (C7) mRNAs in oesophageal carcinoma. Eur J Cancer 37: 1158-1165.
    • (2001) Eur J Cancer , vol.37 , pp. 1158-1165
    • Oka, R.1    Sasagawa, T.2    Ninomiya, I.3    Miwa, K.4    Tanii, H.5    Saijoh, K.6
  • 88
    • 79251490374 scopus 로고    scopus 로고
    • New driver mutations in non-small-cell lung cancer
    • Pao W, Girard N. 2011. New driver mutations in non-small-cell lung cancer. Lancet Oncol 12: 175-180.
    • (2011) Lancet Oncol , vol.12 , pp. 175-180
    • Pao, W.1    Girard, N.2
  • 89
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, Singh B, Heelan R, Rusch V, Fulton L, et al. 2004. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci 101: 13306-13311.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3    Doherty, J.4    Politi, K.5    Sarkaria, I.6    Singh, B.7    Heelan, R.8    Rusch, V.9    Fulton, L.10
  • 90
    • 18244371651 scopus 로고    scopus 로고
    • Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a secondmutation in the EGFR kinase domain
    • doi: 10.1371/journal.pmed.0020073
    • Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, Kris MG, Varmus H. 2005a. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a secondmutation in the EGFR kinase domain. PLoS Med 2: e73. doi: 10.1371/journal.pmed.0020073.
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Miller, V.A.2    Politi, K.A.3    Riely, G.J.4    Somwar, R.5    Zakowski, M.F.6    Kris, M.G.7    Varmus, H.8
  • 98
    • 84855199947 scopus 로고    scopus 로고
    • R Development Core Team. R Foundation for Statistical Computing, Vienna, Austria.
    • R Development Core Team. 2011. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. http://www.R-project.org/.
    • (2011) A Language and Environment for Statistical Computing
  • 99
    • 54249104147 scopus 로고    scopus 로고
    • Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival
    • Ramachandran V, Arumugam T, Wang H, Logsdon CD. 2008. Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival. Cancer Res 68: 7811-7818.
    • (2008) Cancer Res , vol.68 , pp. 7811-7818
    • Ramachandran, V.1    Arumugam, T.2    Wang, H.3    Logsdon, C.D.4
  • 100
    • 34248361968 scopus 로고    scopus 로고
    • Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay
    • Rauch T, Wang Z, Zhang X, Zhong X, Wu X, Lau SK, Kernstine KH, Riggs AD, Pfeifer GP. 2007. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay. Proc Natl Acad Sci 104: 5527-5532.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 5527-5532
    • Rauch, T.1    Wang, Z.2    Zhang, X.3    Zhong, X.4    Wu, X.5    Lau, S.K.6    Kernstine, K.H.7    Riggs, A.D.8    Pfeifer, G.P.9
  • 101
    • 21644463155 scopus 로고    scopus 로고
    • Identification by means of cDNA microarray analyses of gene expression modifications in squamous non-small cell lung cancers as compared to normal bronchial epithelial tissue
    • Remmelink M, Mijatovic T, Gustin A, Mathieu A, Rombaut K, Kiss R, Salmon I, Decaestecker C. 2005. Identification by means of cDNA microarray analyses of gene expression modifications in squamous non-small cell lung cancers as compared to normal bronchial epithelial tissue. Int J Oncol 26: 247-258.
    • (2005) Int J Oncol , vol.26 , pp. 247-258
    • Remmelink, M.1    Mijatovic, T.2    Gustin, A.3    Mathieu, A.4    Rombaut, K.5    Kiss, R.6    Salmon, I.7    Decaestecker, C.8
  • 102
    • 43949091796 scopus 로고    scopus 로고
    • Lung cancer epigenetics and genetics
    • Risch A, Plass C. 2008. Lung cancer epigenetics and genetics. Int J Cancer 123: 1-7.
    • (2008) Int J Cancer , vol.123 , pp. 1-7
    • Risch, A.1    Plass, C.2
  • 103
    • 65849265065 scopus 로고    scopus 로고
    • Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays
    • doi: 10.1186/bcr2121
    • Rodenhiser DI, Andrews J, Kennette W, Sadikovic B, Mendlowitz A, Tuck AB, Chambers AF. 2008. Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays. Breast Cancer Res 10: R62. doi: 10.1186/bcr2121.
    • (2008) Breast Cancer Res , vol.10
    • Rodenhiser, D.I.1    Andrews, J.2    Kennette, W.3    Sadikovic, B.4    Mendlowitz, A.5    Tuck, A.B.6    Chambers, A.F.7
  • 104
    • 79952384705 scopus 로고    scopus 로고
    • Cancer epigenetics reaches mainstream oncology
    • Rodriguez-Paredes M, Esteller M. 2011. Cancer epigenetics reaches mainstream oncology. Nat Med 17: 330-339.
    • (2011) Nat Med , vol.17 , pp. 330-339
    • Rodriguez-Paredes, M.1    Esteller, M.2
  • 105
    • 33845734138 scopus 로고    scopus 로고
    • Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes
    • Rohan S, Tu JJ, Kao J, Mukherjee P, Campagne F, Zhou XK, Hyjek E, Alonso MA, Chen YT. 2006. Gene expression profiling separates chromophobe renal cell carcinoma from oncocytoma and identifies vesicular transport and cell junction proteins as differentially expressed genes. Clin Cancer Res 12: 6937-6945.
    • (2006) Clin Cancer Res , vol.12 , pp. 6937-6945
    • Rohan, S.1    Tu, J.J.2    Kao, J.3    Mukherjee, P.4    Campagne, F.5    Zhou, X.K.6    Hyjek, E.7    Alonso, M.A.8    Chen, Y.T.9
  • 106
    • 46349109888 scopus 로고    scopus 로고
    • Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse adrenal cells
    • Rui X, Tsao J, Scheys JO, Hammer GD, Schimmer BP. 2008. Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse adrenal cells. Endocrinology 149: 3668-3678.
    • (2008) Endocrinology , vol.149 , pp. 3668-3678
    • Rui, X.1    Tsao, J.2    Scheys, J.O.3    Hammer, G.D.4    Schimmer, B.P.5
  • 108
    • 33749995778 scopus 로고    scopus 로고
    • Comparison of gene-expression profiles in parallel bone marrow and peripheral blood samples in acute myeloid leukaemia by real-time polymerase chain reaction
    • Sakhinia E, Farahangpour M, Tholouli E, Liu Yin JA, Hoyland JA, Byers RJ. 2006. Comparison of gene-expression profiles in parallel bone marrow and peripheral blood samples in acute myeloid leukaemia by real-time polymerase chain reaction. J Clin Pathol 59: 1059-1065.
    • (2006) J Clin Pathol , vol.59 , pp. 1059-1065
    • Sakhinia, E.1    Farahangpour, M.2    Tholouli, E.3    Liu Yin, J.A.4    Hoyland, J.A.5    Byers, R.J.6
  • 111
    • 79959743515 scopus 로고    scopus 로고
    • Galectin-4 functions as a tumor suppressor of human colorectal cancer
    • Satelli A, Rao PS, Thirumala S, Rao US. 2011. Galectin-4 functions as a tumor suppressor of human colorectal cancer. Int J Cancer 129: 799-809.
    • (2011) Int J Cancer , vol.129 , pp. 799-809
    • Satelli, A.1    Rao, P.S.2    Thirumala, S.3    Rao, U.S.4
  • 113
    • 0031683862 scopus 로고    scopus 로고
    • The H-cadherin (CDH13) gene is inactivated in human lung cancer
    • Sato M, Mori Y, Sakurada A, Fujimura S, Horii A. 1998. The H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum Genet 103: 96-101.
    • (1998) Hum Genet , vol.103 , pp. 96-101
    • Sato, M.1    Mori, Y.2    Sakurada, A.3    Fujimura, S.4    Horii, A.5
  • 117
    • 79959568138 scopus 로고    scopus 로고
    • DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma
    • doi: 10.1371/journal.pone.0021443
    • Selamat SA, Galler JS, Joshi AD, Fyfe MN, Campan M, Siegmund KD, Kerr KM, Laird-Offringa IA. 2011. DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma. PLoS ONE 6: e21443. doi: 10.1371/journal.pone.0021443.
    • (2011) PLoS ONE , vol.6
    • Selamat, S.A.1    Galler, J.S.2    Joshi, A.D.3    Fyfe, M.N.4    Campan, M.5    Siegmund, K.D.6    Kerr, K.M.7    Laird-Offringa, I.A.8
  • 119
    • 80955180970 scopus 로고    scopus 로고
    • High expression of stratifin is a universal abnormality during the course of malignant progression of early-stage lung adenocarcinoma
    • Shiba-Ishii A, Kano J, Morishita Y, Sato Y, Minami Y, Noguchi M. 2011. High expression of stratifin is a universal abnormality during the course of malignant progression of early-stage lung adenocarcinoma. Int J Cancer 129: 2445-2453.
    • (2011) Int J Cancer , vol.129 , pp. 2445-2453
    • Shiba-Ishii, A.1    Kano, J.2    Morishita, Y.3    Sato, Y.4    Minami, Y.5    Noguchi, M.6
  • 120
    • 79960563683 scopus 로고    scopus 로고
    • Identification of epigenetically silenced genes in human pancreatic cancer by a novel method "microarray coupled with methyl-CpG targeted transcriptional activation" (MeTA-array)
    • Shimizu H, Horii A, Sunamura M, Motoi F, Egawa S, Unno M, Fukushige S. 2011. Identification of epigenetically silenced genes in human pancreatic cancer by a novel method "microarray coupled with methyl-CpG targeted transcriptional activation" (MeTA-array). Biochem Biophys Res Commun 411: 162-167.
    • (2011) Biochem Biophys Res Commun , vol.411 , pp. 162-167
    • Shimizu, H.1    Horii, A.2    Sunamura, M.3    Motoi, F.4    Egawa, S.5    Unno, M.6    Fukushige, S.7
  • 121
    • 0037118586 scopus 로고    scopus 로고
    • HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas
    • Shiraishi M, Sekiguchi A, Oates AJ, Terry MJ, Miyamoto Y. 2002. HOX gene clusters are hotspots of de novo methylation in CpG islands of human lung adenocarcinomas. Oncogene 21: 3659-3662.
    • (2002) Oncogene , vol.21 , pp. 3659-3662
    • Shiraishi, M.1    Sekiguchi, A.2    Oates, A.J.3    Terry, M.J.4    Miyamoto, Y.5
  • 123
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R. 2003. Statistical significance for genomewide studies. Proc Natl Acad Sci 100: 9440-9445.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 124
    • 34648815009 scopus 로고    scopus 로고
    • Lung cancer in never smokers - A different disease
    • Sun S, Schiller JH, Gazdar AF. 2007. Lung cancer in never smokers - a different disease. Nat Rev Cancer 7: 778-790.
    • (2007) Nat Rev Cancer , vol.7 , pp. 778-790
    • Sun, S.1    Schiller, J.H.2    Gazdar, A.F.3
  • 125
    • 84055209996 scopus 로고    scopus 로고
    • Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer
    • Sunaga N, Imai H, Shimizu K, Shames DS, Kakegawa S, Girard L, Sato M, Kaira K, Ishizuka T, Gazdar AF, et al. 2012. Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer. Int J Cancer 130: 1733-1744.
    • (2012) Int J Cancer , vol.130 , pp. 1733-1744
    • Sunaga, N.1    Imai, H.2    Shimizu, K.3    Shames, D.S.4    Kakegawa, S.5    Girard, L.6    Sato, M.7    Kaira, K.8    Ishizuka, T.9    Gazdar, A.F.10
  • 126
    • 33646345615 scopus 로고    scopus 로고
    • Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer
    • Suzuki M, Shigematsu H, Iizasa T, Hiroshima K, Nakatani Y, Minna JD, Gazdar AF, Fujisawa T. 2006. Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer. Cancer 106: 2200-2207.
    • (2006) Cancer , vol.106 , pp. 2200-2207
    • Suzuki, M.1    Shigematsu, H.2    Iizasa, T.3    Hiroshima, K.4    Nakatani, Y.5    Minna, J.D.6    Gazdar, A.F.7    Fujisawa, T.8
  • 128
  • 129
    • 79956368802 scopus 로고    scopus 로고
    • Methylation profile of single hepatocytes derived from hepatitis B virus-related hepatocellular carcinoma
    • doi: 10.1371/journal.pone.0019862
    • Tao R, Li J, Xin J, Wu J, Guo J, Zhang L, Jiang L, Zhang W, Yang Z, Li L. 2011. Methylation profile of single hepatocytes derived from hepatitis B virus-related hepatocellular carcinoma. PLoS ONE 6: e19862. doi: 10.1371/journal.pone.0019862.
    • (2011) PLoS ONE , vol.6
    • Tao, R.1    Li, J.2    Xin, J.3    Wu, J.4    Guo, J.5    Zhang, L.6    Jiang, L.7    Zhang, W.8    Yang, Z.9    Li, L.10
  • 130
    • 48549101423 scopus 로고    scopus 로고
    • CpG island methylator phenotype (CIMP) in cancer: Causes and implications
    • Teodoridis JM, Hardie C, Brown R. 2008. CpG island methylator phenotype (CIMP) in cancer: Causes and implications. Cancer Lett 268: 177-186.
    • (2008) Cancer Lett , vol.268 , pp. 177-186
    • Teodoridis, J.M.1    Hardie, C.2    Brown, R.3
  • 131
    • 57349184083 scopus 로고    scopus 로고
    • Mining the epigenome for methylated genes in lung cancer
    • Tessema M, Belinsky SA. 2008. Mining the epigenome for methylated genes in lung cancer. Proc Am Thorac Soc 5: 806-810.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 806-810
    • Tessema, M.1    Belinsky, S.A.2
  • 133
    • 77956546070 scopus 로고    scopus 로고
    • Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells
    • doi: 10.1371/journal.pone.0010594
    • Tommasi S, Kim SI, Zhong X, Wu X, Pfeifer GP, Besaratinia A. 2010. Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells. PLoS ONE 5: e10594. doi: 10.1371/journal.pone.0010594.
    • (2010) PLoS ONE , vol.5
    • Tommasi, S.1    Kim, S.I.2    Zhong, X.3    Wu, X.4    Pfeifer, G.P.5    Besaratinia, A.6
  • 135
  • 136
    • 2942558369 scopus 로고    scopus 로고
    • TDAG51 mediates the effects of insulin-like growth factor I (IGF-I) on cell survival
    • Toyoshima Y, Karas M, Yakar S, Dupont J, Lee H, LeRoith D. 2004. TDAG51 mediates the effects of insulin-like growth factor I (IGF-I) on cell survival. J Biol Chem 279: 25898-25904.
    • (2004) J Biol Chem , vol.279 , pp. 25898-25904
    • Toyoshima, Y.1    Karas, M.2    Yakar, S.3    Dupont, J.4    Lee, H.5    LeRoith, D.6
  • 138
    • 79551563284 scopus 로고    scopus 로고
    • International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma
    • Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, et al. 2011. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 6: 244-285.
    • (2011) J Thorac Oncol , vol.6 , pp. 244-285
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3    Nicholson, A.G.4    Geisinger, K.R.5    Yatabe, Y.6    Beer, D.G.7    Powell, C.A.8    Riely, G.J.9    Van Schil, P.E.10
  • 142
  • 145
    • 78149491523 scopus 로고    scopus 로고
    • Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-a and survivin
    • doi: 10.1186/bcr2586
    • Vanderlaag KE, Hudak S, Bald L, Fayadat-Dilman L, Sathe M, Grein J, Janatpour MJ. 2010. Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-a and survivin. Breast Cancer Res 12: R32. doi: 10.1186/bcr2586.
    • (2010) Breast Cancer Res , vol.12
    • Vanderlaag, K.E.1    Hudak, S.2    Bald, L.3    Fayadat-Dilman, L.4    Sathe, M.5    Grein, J.6    Janatpour, M.J.7
  • 146
    • 34248219062 scopus 로고    scopus 로고
    • Sequence, "subtle"alternative splicing and expression of the CYYR1 (cysteine/tyrosine-rich 1) mRNA in human neuroendocrine tumors
    • doi: 10.1186/1471-2407-7-66
    • Vitale L, Frabetti F, Huntsman SA, Canaider S, Casadei R, Lenzi L, Facchin F, Carinci P, Zannotti M, Coppola D, et al. 2007. Sequence, "subtle"alternative splicing and expression of the CYYR1 (cysteine/tyrosine-rich 1) mRNA in human neuroendocrine tumors. BMC Cancer 7: 66. doi: 10.1186/1471-2407-7-66.
    • (2007) BMC Cancer , vol.7 , pp. 66
    • Vitale, L.1    Frabetti, F.2    Huntsman, S.A.3    Canaider, S.4    Casadei, R.5    Lenzi, L.6    Facchin, F.7    Carinci, P.8    Zannotti, M.9    Coppola, D.10
  • 148
    • 0346792725 scopus 로고    scopus 로고
    • TRAIL and apoptosis induction by TNF-family death receptors
    • Wang S, El-Deiry WS. 2003. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene 22: 8628-8633.
    • (2003) Oncogene , vol.22 , pp. 8628-8633
    • Wang, S.1    El-Deiry, W.S.2
  • 156
    • 0035042611 scopus 로고    scopus 로고
    • SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
    • Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE, Harris CC, Herman JG. 2001. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet 28: 29-35.
    • (2001) Nat Genet , vol.28 , pp. 29-35
    • Yoshikawa, H.1    Matsubara, K.2    Qian, G.S.3    Jackson, P.4    Groopman, J.D.5    Manning, J.E.6    Harris, C.C.7    Herman, J.G.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.