Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

Nature Medicine

Volumn 18, Issue 3, 2012, Pages 382-384

  Lipson, Doron ^a   Capelletti, Marzia ^b   Yelensky, Roman ^a   Otto, Geoff ^a   Parker, Alex ^a   Jarosz, Mirna ^a   Curran, John A ^a   Balasubramanian, Sohail ^a   Bloom, Troy ^a   Brennan, Kristina W ^a   Donahue, Amy ^a   Downing, Sean R ^a   Frampton, Garrett M ^a   Garcia, Lazaro ^a   Juhn, Frank ^a   Mitchell, Kathy C ^a   White, Emily ^a   White, Jared ^a   Zwirko, Zac ^a   Peretz, Tamar ^c   Nechushtan, Hovav ^c   Soussan Gutman, Lior ^d   Kim, Jhingook ^e   Sasaki, Hidefumi ^f   Kim, Hyeong Ryul ^g   Park, Seung Il ^g   Ercan, Dalia ^b   Sheehan, Christine E ^h   Ross, Jeffrey S ^a,h   Cronin, Maureen T ^a   Jänne, Pasi A ^b   Stephens, Philip J ^a   more..

^a FOUNDATION MEDICINE   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d TEVA PHARMACEUTICALS   (Israel)

^e Sungkyunkwan University School of Medicine   (South Korea)

^f NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^g University of Ulsan College of Medicine   (South Korea)

^h ALBANY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; ACTIVIN RECEPTOR LIKE KINASE RET HYBRID PROTEIN; CRIZOTINIB; CYCLIN DEPENDENT KINASE INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; FORMALDEHYDE; GEFITINIB; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN RET; UNCLASSIFIED DRUG;

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; GENE FUSION; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; HUMAN; HUMAN TISSUE; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; TUMOR BIOPSY;

ANIMALS; BIOPSY; CARCINOMA, NON-SMALL-CELL LUNG; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; KINESIN; LUNG NEOPLASMS; MICE; NIH 3T3 CELLS; ONCOGENE PROTEINS, FUSION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 84862776857     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2673     Document Type: Article

References (20)

1. Forbes, S.A. et al. Nucleic Acids Res. 39, D945-D950 (2011).
2. Lièvre, A. et al. Cancer Res. 66, 3992-3995 (2006).
3. Di Nicolantonio, F. et al. J. Clin. Oncol. 26, 5705-5712 (2008).
4. Wertz, I.E. et al. Nature 471, 110-114 (2011).
5. Turner, N., Tutt, A. & Ashworth, A. Curr. Opin. Pharmacol. 5, 388-393 (2005).
6. Wilson, C.H., McIntyre, R.E., Arends, M.J. & Adams, D.J. Oncogene 29, 4567-4575 (2010).
7. Engelman, J.A. et al. Nat. Med. 14, 1351-1356 (2008).
8. Soda, M. et al. Nature 448, 561-566 (2007).
9. Kwak, E.L. et al. N. Engl. J. Med. 363, 1693-1703 (2010).
10. Pao, W. et al. PLoS Med. 2, e17 (2005).
11. Chapman, P.B. et al. N. Engl. J. Med. 364, 2507-2516 (2011).
12. Pao, W. et al. Proc. Natl. Acad. Sci. USA 101, 13306-13311 (2004).
13. Vassilev, L.T. et al. Science 303, 844-848 (2004).
14. Finn, R.S. et al. Breast Cancer Res. 11, R77 (2009).
15. Toogood, P.L. et al. J. Med. Chem. 48, 2388-2406 (2005).
16. Di Nicolantonio, F. et al. J. Clin. Invest. 120, 2858-2866 (2010).
17. Wang, Y. et al. Blood 114, 5024-5033 (2009).
18. Wong, D.W. et al. Cancer 117, 2709-2718 (2011).
19. Fusco, A. et al. Nature 328, 170-172 (1987).
20. Henderson, Y.C., Ahn, S.H., Kang, Y. & Clayman, G.L. Clin. Cancer Res. 14, 4908-4914 (2008).