Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma

Oncogene

Volumn 24, Issue 42, 2005, Pages 6406-6417

  Niwa, Yasuharu ^a   Kanda, Hiroaki ^a   Shikauchi, Yuko ^a   Saiura, Akio ^a   Matsubara, Kenichi ^b   Kitagawa, Tomoyuki ^a   Yamamoto, Junji ^a   Kubo, Takahiko ^a   Yoshikawa, Hirohide ^a  

^a CANCER INSTITUTE   (Japan)

^b DNA CHIP RESEARCH INC   (Japan)

Author keywords

FAK; HCC; JAK STAT; SOCS 3

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PROTEIN; PROTEIN SUPPRESSOR OF CYTOKINE SIGNALING 3; STAT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE SEQUENCE; GENE SILENCING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METHYLATION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CELL LINE, TUMOR; CELL MOVEMENT; DNA METHYLATION; DNA-BINDING PROTEINS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE SILENCING; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER NEOPLASMS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 27144433826     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208788     Document Type: Article

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