Sox17, the canonical Wnt antagonist, is epigenetically inactivated by promoter methylation in human breast cancer

Breast Cancer Research and Treatment

Volumn 119, Issue 3, 2010, Pages 601-612

  Fu, De Yuan ^a   Wang, Zhi Min ^b   Li Chen, ^a   Wang, Bei Lan ^b   Shen, Zhen Zhou ^a   Huang, Wei ^b   Shao, Zhi Ming ^a  

^a FUDAN UNIVERSITY   (China)

^b CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

Author keywords

Breast cancer; DNA methylation; Sox17; Wnt signaling

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BETA CATENIN; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SOX17; WNT PROTEIN;

ADULT; ARTICLE; BREAST CANCER; CANCER STAGING; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; METHYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; BASE SEQUENCE; BETA CATENIN; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SOXF TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR MARKERS, BIOLOGICAL; WNT PROTEINS;

EID: 74849121190     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0339-8     Document Type: Article

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