SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice

FASEB Journal

Volumn 26, Issue 2, 2012, Pages 555-566

  Seifert, Erin L ^a,b,d   Caron, Annabelle Z ^a,b   Morin, Katy ^a,b   Coulombe, Josée ^a,b   He, Xiao Hong ^a,b   Jardine, Karen ^a,b   Dewar Darch, Danielle ^a,b   Boekelheide, Kim ^c   Harper, Mary Ellen ^b   McBurney, Michael W ^a,b  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c BROWN UNIVERSITY   (United States)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Knock in; Metabolism; Sirtuin

Indexed keywords

HISTIDINE; SIRTUIN 1;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC RESTRICTION; CATALYSIS; FEMALE FERTILITY; FEMALE STERILITY; GROWTH RATE; HOMEOSTASIS; HUMAN; HUMAN CELL; LOCOMOTION; MALE FERTILITY; MOUSE; NONHUMAN; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CALORIC RESTRICTION; CONSERVED SEQUENCE; DNA PRIMERS; FEMALE; FERTILITY; HISTIDINE; HOMEOSTASIS; INFERTILITY, MALE; MALE; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MOTOR ACTIVITY; MUTANT PROTEINS; MUTATION, MISSENSE; POINT MUTATION; PREGNANCY; SIRTUIN 1; SPERMATOGENESIS;

ANIMALIA; MUS;

EID: 84863403463     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-193979     Document Type: Article

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