Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents

International Journal of Environmental Research and Public Health

Volumn 9, Issue 6, 2012, Pages 2075-2091

  Cowell, Ian G ^a   Austin, Caroline A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

AML; Carcinogen; Epirubicin; Etoposide; Leukemia; Mitoxantrone; TOP2; Topoisomerase II; Transcription; Translocation

Indexed keywords

CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DEOXYRIBONUCLEASE I; DNA TOPOISOMERASE (ATP HYDROLYSING); EPIRUBICIN; ETOPOSIDE; GYRASE INHIBITOR; MELPHALAN; MITOXANTRONE; MIXED LINEAGE LEUKEMIA PROTEIN; NITROSOUREA; TENIPOSIDE;

CANCER; CARCINOGEN; CHEMOTHERAPY; DRUG; ENZYME ACTIVITY; ETIOLOGY;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LEUKEMIA; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CHROMOSOME TRANSLOCATION; DISEASE ASSOCIATION; DNA CLEAVAGE; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; ENZYME ACTIVITY; GENE TRANSLOCATION; HUMAN; IGH GENE; MLL GENE; MOLECULAR PATHOLOGY; MULTIPLE SCLEROSIS; NONHUMAN; ONCOGENE; ONCOGENE MYC; PROTEIN TARGETING; REVIEW;

EID: 84863228471     PISSN: None     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph9062075     Document Type: Review

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