Evidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemia

Blood

Volumn 115, Issue 2, 2010, Pages 326-330

  Mays, Ashley N ^a   Osheroff, Neil ^b   Xiao, Yuanyuan ^c   Wiemels, Joseph L ^c   Felix, Carolyn A ^d   Byl, Jo Ann W ^b   Saravanamuttu, Kandeepan ^e   Peniket, Andrew ^f   Corser, Robert ^g   Chang, Cherry ^h   Hoyle, Christine ⁱ   Parker, Anne N ^j   Hasan, Syed K ^k,l   Lo Coco, Francesco ^k,l   Solomon, Ellen ^a   Grimwade, David ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e LINCOLN COUNTY HOSPITAL   (United Kingdom)

^f JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^g QUEEN ALEXANDRA HOSPITAL   (United Kingdom)

^h ROYAL DERBY HOSPITAL   (United Kingdom)

ⁱ GLAN CLWYD HOSPITAL   (United Kingdom)

^j BEATSON WEST OF SCOTLAND CANCER CENTRE   (United Kingdom)

^k UNIVERSITY OF ROME TOR VERGATA   (Italy)

^l IRCCS FONDAZIONE SANTA LUCIA   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; CYCLOPHOSPHAMIDE; DNA TOPOISOMERASE (ATP HYDROLYSING); EPIRUBICIN; FLUOROURACIL; METHOTREXATE; MITOXANTRONE; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN; RARA PROTEIN; RETINOIC ACID; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; NUCLEAR PROTEIN; PML PROTEIN, HUMAN; RETINOIC ACID RECEPTOR; RETINOIC ACID RECEPTOR ALPHA; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ADULT; ARTICLE; BREAST CARCINOMA; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CHROMOSOME 15; CHROMOSOME 17; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; DNA DAMAGE; GENE CLUSTER; GENE LOCUS; GENETIC SUSCEPTIBILITY; GENOMICS; HUMAN; INTRON; MULTIMODALITY CANCER THERAPY; MULTIPLE CYCLE TREATMENT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; BREAST TUMOR; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; GENE TRANSLOCATION; GENETICS; METABOLISM; MIDDLE AGED; QUANTITATIVE TRAIT LOCUS; SECOND CANCER;

ADULT; ANTIBIOTICS, ANTINEOPLASTIC; BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 17; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II; EPIRUBICIN; FEMALE; HUMANS; INTRONS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MIDDLE AGED; MITOXANTRONE; NEOPLASMS, SECOND PRIMARY; NUCLEAR PROTEINS; QUANTITATIVE TRAIT LOCI; RECEPTORS, RETINOIC ACID; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 75649084232     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-07-235051     Document Type: Article

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