-
1
-
-
0025833975
-
Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias
-
Ziemin-Van Der Poel, S., McCabe, N.R., Gill, H.J., Espinosa III, R., Patel, Y., Harden, A., Rubinelli, P., Smith, S.D., LeBeau, M.M., Rowley, J.D. et al. (1991) Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias. Proc. Natl Acad. Sci. USA, 88, 10735-10739.
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 10735-10739
-
-
Ziemin-Van Der Poel, S.1
McCabe, N.R.2
Gill, H.J.3
Espinosa R. III4
Patel, Y.5
Harden, A.6
Rubinelli, P.7
Smith, S.D.8
Lebeau, M.M.9
Rowley, J.D.10
-
2
-
-
0026493686
-
The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase
-
Gu, Y., Cimino, G., Alder, H., Nakamura, T., Prasad, R., Canaani, O., Moir, D.T., Jones, C., Nowell, P.C., Croce, C.M. et al. (1992) The (4;11)(q21;q23) chromosome translocations in acute leukemias involve the VDJ recombinase. Proc. Natl Acad. Sci. USA, 89, 10464-10468.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 10464-10468
-
-
Gu, Y.1
Cimino, G.2
Alder, H.3
Nakamura, T.4
Prasad, R.5
Canaani, O.6
Moir, D.T.7
Jones, C.8
Nowell, P.C.9
Croce, C.M.10
-
3
-
-
0026936328
-
A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias
-
Djabali, M., Selleri Parry, P., Bower, M., Young, B.D. and Evans, G.A. (1992) A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias. Nature Genet., 2, 113-118.
-
(1992)
Nature Genet.
, vol.2
, pp. 113-118
-
-
Djabali, M.1
Selleri Parry, P.2
Bower, M.3
Young, B.D.4
Evans, G.A.5
-
4
-
-
0026454451
-
Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocation in acute leukemias
-
Tkachuk, D.C., Kohler, S. and Cleary, M.L. (1992) Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocation in acute leukemias. Cell, 71, 691-700.
-
(1992)
Cell
, vol.71
, pp. 691-700
-
-
Tkachuk, D.C.1
Kohler, S.2
Cleary, M.L.3
-
6
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
Thirman, M.J., Gill, H.J., Burnett, R.C., Mbangkollo, D., Mccabe, N.R., Kobayashi, H., Ziemin-Van Der Poel, S., Kaneko, Y., Morgan, R., Sandberg, A.A. et al. (1993) Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N. Engl. J. Med., 329, 909-914.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
Mbangkollo, D.4
McCabe, N.R.5
Kobayashi, H.6
Ziemin-Van Der Poel, S.7
Kaneko, Y.8
Morgan, R.9
Sandberg, A.A.10
-
7
-
-
0032411481
-
The critical role of chromosome translocations in human leukemias
-
Rowley, J.D. (1998) The critical role of chromosome translocations in human leukemias. Annu. Rev. Genet., 32, 495-519.
-
(1998)
Annu. Rev. Genet.
, vol.32
, pp. 495-519
-
-
Rowley, J.D.1
-
8
-
-
0033065099
-
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)
-
Osaka, M., Rowley, J.D. and Zeleznik-Le, N.J. (1999) MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25). Proc. Natl Acad. Sci. USA, 96, 6428-6433.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 6428-6433
-
-
Osaka, M.1
Rowley, J.D.2
Zeleznik-Le, N.J.3
-
9
-
-
11544323440
-
t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes
-
Megonigal, M.D., Rappaport, E.F., Jones, D.H., Williams, T.M., Lovett, B.D., Kelly, K.M., Lerou, P.H., Moulton, T., Budarf, M.L. and Felix, C.A. (1998) t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes. Proc. Natl Acad. Sci. USA, 95, 6413-6418.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 6413-6418
-
-
Megonigal, M.D.1
Rappaport, E.F.2
Jones, D.H.3
Williams, T.M.4
Lovett, B.D.5
Kelly, K.M.6
Lerou, P.H.7
Moulton, T.8
Budarf, M.L.9
Felix, C.A.10
-
10
-
-
0028341345
-
ALL-I partial duplication in acute leukemia
-
Schichman, S., Caligiuri, M., Gu, Y., Strout, M., Canaani, E., Bloomfield, C.D. and Croce, C.M. (1994) ALL-1 partial duplication in acute leukemia. Proc. Natl Acad. Sci. USA, 91, 6236-6239.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 6236-6239
-
-
Schichman, S.1
Caligiuri, M.2
Gu, Y.3
Strout, M.4
Canaani, E.5
Bloomfield, C.D.6
Croce, C.M.7
-
11
-
-
0029142842
-
Partial duplication of HRX in acute leukemia with trisomy 11
-
Bernard, O.A., Romana, S.P., Schichman, S.A., Mauchauffe, M., Jonveaux, P. and Berger, R. (1995) Partial duplication of HRX in acute leukemia with trisomy 11. Leukemia, 9, 1487-1490.
-
(1995)
Leukemia
, vol.9
, pp. 1487-1490
-
-
Bernard, O.A.1
Romana, S.P.2
Schichman, S.A.3
Mauchauffe, M.4
Jonveaux, P.5
Berger, R.6
-
12
-
-
0032925075
-
Analysis of the region of the 5′ end of the MLL gene involved in genomic duplication events
-
Wiedeman, L.M., MacGregor, A. and Caldas, C. (1999) Analysis of the region of the 5′ end of the MLL gene involved in genomic duplication events. Br. J. Haematol, 105, 256-264.
-
(1999)
Br. J. Haematol
, vol.105
, pp. 256-264
-
-
Wiedeman, L.M.1
Macgregor, A.2
Caldas, C.3
-
13
-
-
0029930974
-
Infant leukaemia biology, aetiology and treatment
-
Greaves, M.F. (1996) Infant leukaemia biology, aetiology and treatment. Leukemia, 10, 372-377.
-
(1996)
Leukemia
, vol.10
, pp. 372-377
-
-
Greaves, M.F.1
-
14
-
-
0028057282
-
Molecular rearrangements of chromosome band 11q23 are common in infant AML and are strongly correlated with monocytic or myelomonocytic phenotypes
-
Sorensen, P.H.B., Chen, C.S., Smith, F.O., Arthur, D.C., Bernstein, D.C., Domer, P.H., Korsmeyer, S.J., Hammond, G.D. and Kersey J.H. (1994) Molecular rearrangements of chromosome band 11q23 are common in infant AML and are strongly correlated with monocytic or myelomonocytic phenotypes. J. Clin. Invest., 93, 429-437.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 429-437
-
-
Sorensen, P.H.B.1
Chen, C.S.2
Smith, F.O.3
Arthur, D.C.4
Bernstein, D.C.5
Domer, P.H.6
Korsmeyer, S.J.7
Hammond, G.D.8
Kersey, J.H.9
-
15
-
-
0029086321
-
Detection of 11q23/MLL rearrangements in infant leukemias with fluorescent in situ hybridization and molecular analysis
-
Martinez-Climente, J.A., Thirman, M.J., Espinosa III, R., Le Beau, M.M. and Rowley, J.D. (1995) Detection of 11q23/MLL rearrangements in infant leukemias with fluorescent in situ hybridization and molecular analysis. Leukemia, 9, 1299-1304.
-
(1995)
Leukemia
, vol.9
, pp. 1299-1304
-
-
Martinez-Climente, J.A.1
Thirman, M.J.2
Espinosa R. III3
Le Beau, M.M.4
Rowley, J.D.5
-
16
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu, L.F. (1989) DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem., 58, 351-375.
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
17
-
-
0025189757
-
Induction of mammalian topoisomerase II dependent DNA cleavage by non-intercalative flavonoids, genistein and orobol
-
Yamashita, Y., Kawada, S. and Nakano H. (1990) Induction of mammalian topoisomerase II dependent DNA cleavage by non-intercalative flavonoids, genistein and orobol. Biochem. Pharmacol., 39, 737-744.
-
(1990)
Biochem. Pharmacol.
, vol.39
, pp. 737-744
-
-
Yamashita, Y.1
Kawada, S.2
Nakano, H.3
-
18
-
-
0034712748
-
Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia
-
Strick, R., Strissel, P.L., Borgers, S., Smith, S.L. and Rowley, J.D. (2000) Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia. Proc. Natl Acad. Sci. USA, 4790-4795.
-
(2000)
Proc. Natl Acad. Sci. USA
, pp. 4790-4795
-
-
Strick, R.1
Strissel, P.L.2
Borgers, S.3
Smith, S.L.4
Rowley, J.D.5
-
20
-
-
0027132061
-
Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II
-
Gill Super, H.J., McCabe, N.R., Thirman, M., Larson, R.A., Le Beau M.M., Pedersen-Bjergaard, J., Preben, P., Diaz, M. and Rowley, J.D. (1993) Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II. Blood, 82, 3705-3711.
-
(1993)
Blood
, vol.82
, pp. 3705-3711
-
-
Gill Super, H.J.1
McCabe, N.R.2
Thirman, M.3
Larson, R.A.4
Le Beau, M.M.5
Pedersen-Bjergaard, J.6
Preben, P.7
Diaz, M.8
Rowley, J.D.9
-
21
-
-
0027319749
-
HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities
-
Hunger, S.P., Tkachuk, D.C., Amylon, M.D., Link, M.P., Carroll, A.J., Welborn, J.L., Willman, C.L. and Cleary M.L. (1993) HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities. Blood, 81, 3197-3203.
-
(1993)
Blood
, vol.81
, pp. 3197-3203
-
-
Hunger, S.P.1
Tkachuk, D.C.2
Amylon, M.D.3
Link, M.P.4
Carroll, A.J.5
Welborn, J.L.6
Willman, C.L.7
Cleary, M.L.8
-
22
-
-
0026079804
-
Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia
-
Piu, C.-H., Riberio, R.C., Hancock, M.L., Rivera, G.K., Evans, W.E., Raimondi, S.C., Head, D.R., Behm, F.G., Mahmoud, M.H., Sandlund, J.T. and Crist, W.M. (1991) Acute myeloid leukemia in children treated with epipodophyllotoxins for acute lymphoblastic leukemia. N. Engl. J. Med., 325, 1682-1687.
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 1682-1687
-
-
Piu, C.-H.1
Riberio, R.C.2
Hancock, M.L.3
Rivera, G.K.4
Evans, W.E.5
Raimondi, S.C.6
Head, D.R.7
Behm, F.G.8
Mahmoud, M.H.9
Sandlund, J.T.10
Crist, W.M.11
-
23
-
-
0028650364
-
Epidemiology of childhood leukemia, with a focus on infants
-
Ross, J.A., Davies, S.M., Potter, J.D. and Robison, L.L. (1994) Epidemiology of childhood leukemia, with a focus on infants. Epidemiol. Rev., 16, 243-272.
-
(1994)
Epidemiol. Rev.
, vol.16
, pp. 243-272
-
-
Ross, J.A.1
Davies, S.M.2
Potter, J.D.3
Robison, L.L.4
-
24
-
-
0029113177
-
Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4:11)
-
Domer, P.H., Head, D.R., Renganathan, N., Raimondi, S.C., Yang, E. and Atlas, M. (1995) Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4:11). Leukemia, 9, 1305-1312.
-
(1995)
Leukemia
, vol.9
, pp. 1305-1312
-
-
Domer, P.H.1
Head, D.R.2
Renganathan, N.3
Raimondi, S.C.4
Yang, E.5
Atlas, M.6
-
25
-
-
0031731102
-
Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints
-
Atlas, M., Head, D., Behm, F., Schmidt, E., Zeleznik-Le, N.J., Roe, B.A., Burian, D. and Domer, P.H. (1998) Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints. Leukemia, 12, 1895-1902.
-
(1998)
Leukemia
, vol.12
, pp. 1895-1902
-
-
Atlas, M.1
Head, D.2
Behm, F.3
Schmidt, E.4
Zeleznik-Le, N.J.5
Roe, B.A.6
Burian, D.7
Domer, P.H.8
-
26
-
-
0027382455
-
MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13
-
Iida, S., Seto, M., Yamamoto, K., Komatsu, H., Tojo, A., Asano, S., Kamada, N., Ariyoshi, Y., Takahashi, T. and Ueda, R. (1993) MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine/proline rich protein homologous to MLLT1 on 19p13. Oncogene, 11, 3085-3092.
-
(1993)
Oncogene
, vol.11
, pp. 3085-3092
-
-
Iida, S.1
Seto, M.2
Yamamoto, K.3
Komatsu, H.4
Tojo, A.5
Asano, S.6
Kamada, N.7
Ariyoshi, Y.8
Takahashi, T.9
Ueda, R.10
-
27
-
-
0027173436
-
Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs
-
Nakamura, T., Alder, H., Hu, Y., Prasad, R., Canaani, O., Kamada, N., Gale, R.P., Lange, B., Crist, W.M., Nowell, P.C. et al. (1993) Genes on chromosomes 4, 9, and 19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc. Natl Acad. Sci. USA, 90, 4631-4635.
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, pp. 4631-4635
-
-
Nakamura, T.1
Alder, H.2
Hu, Y.3
Prasad, R.4
Canaani, O.5
Kamada, N.6
Gale, R.P.7
Lange, B.8
Crist, W.M.9
Nowell, P.C.10
-
28
-
-
0028325337
-
A reverse transcriptase-polymerase chain reaction detects heterogeneous chimeric mRNAs in leukemias with 11q23 abnormalities
-
Yamamoto, K., Seto, M., Iida, S., Komatsu, H., Kamada, N., Kojima, S., Kodera, Y., Nakazawa, S., Saito, H., Takahashi, T. et al. (1994) A reverse transcriptase-polymerase chain reaction detects heterogeneous chimeric mRNAs in leukemias with 11q23 abnormalities. Blood, 83, 2912-2921.
-
(1994)
Blood
, vol.83
, pp. 2912-2921
-
-
Yamamoto, K.1
Seto, M.2
Iida, S.3
Komatsu, H.4
Kamada, N.5
Kojima, S.6
Kodera, Y.7
Nakazawa, S.8
Saito, H.9
Takahashi, T.10
-
29
-
-
0028169259
-
ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells
-
Rubnitz, J.E., Morrissey, J., Savage, P.A. and Cleary M.L. (1994) ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells. Blood, 84, 1747-1752.
-
(1994)
Blood
, vol.84
, pp. 1747-1752
-
-
Rubnitz, J.E.1
Morrissey, J.2
Savage, P.A.3
Cleary, M.L.4
-
30
-
-
15844394270
-
An MLL-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes
-
Corral, J., Lavenir, I., Impey, H., Warren, A.J., Forster, A., Larson, T.A., Bell, S., McKenzie, A.N., King, G. and Rabbitts, T.H. (1996) An MLL-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes. Cell, 85, 853-861.
-
(1996)
Cell
, vol.85
, pp. 853-861
-
-
Corral, J.1
Lavenir, I.2
Impey, H.3
Warren, A.J.4
Forster, A.5
Larson, T.A.6
Bell, S.7
McKenzie, A.N.8
King, G.9
Rabbitts, T.H.10
-
31
-
-
0033168716
-
The Mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis
-
Dobson, C.L., Warren, A.J., Pannell, R., Forster, A., Lavenir, I., Corral, J., Smith, A.J. and Rabbitts, T.H. (1999) The Mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis. EMBO J., 18, 3564-3574.
-
(1999)
EMBO J.
, vol.18
, pp. 3564-3574
-
-
Dobson, C.L.1
Warren, A.J.2
Pannell, R.3
Forster, A.4
Lavenir, I.5
Corral, J.6
Smith, A.J.7
Rabbitts, T.H.8
-
32
-
-
0033611566
-
Establishment of an inducible expression system of chimeric MLL-LTG9 protein and inhibition of Hox a7, Hox b7 and Hox c9 expression by MLL-LTG9 in 32Dc13 cells
-
Joh, T., Hosokawa, Y., Suzuki, R., Takahashi, T. and Seto M. (1999) Establishment of an inducible expression system of chimeric MLL-LTG9 protein and inhibition of Hox a7, Hox b7 and Hox c9 expression by MLL-LTG9 in 32Dc13 cells. Oncogene, 18, 1125-1130.
-
(1999)
Oncogene
, vol.18
, pp. 1125-1130
-
-
Joh, T.1
Hosokawa, Y.2
Suzuki, R.3
Takahashi, T.4
Seto, M.5
-
33
-
-
0029890796
-
Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias
-
Nilson, I., Lochner, K., Siegler, G., Greil, J., Beck, J.D., Fey, G.H. and Marschalek, R. (1996) Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias. Br. J. Haematol, 93, 966-972.
-
(1996)
Br. J. Haematol
, vol.93
, pp. 966-972
-
-
Nilson, I.1
Lochner, K.2
Siegler, G.3
Greil, J.4
Beck, J.D.5
Fey, G.H.6
Marschalek, R.7
-
34
-
-
0030041634
-
Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment related acute myeloid leukemia: Correlation with scaffold attachment regions and topoisomerase II consensus binding sites
-
Strissel, P.L., Gill-Super, H., Thirman, M.J., Pomykala, H., Yonebayashi, Y., Tanabe, S., Zeleznik-Le, N. and Rowley, J.D. (1996) Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment related acute myeloid leukemia: Correlation with scaffold attachment regions and topoisomerase II consensus binding sites. Blood, 87, 1912-1922.
-
(1996)
Blood
, vol.87
, pp. 1912-1922
-
-
Strissel, P.L.1
Gill-Super, H.2
Thirman, M.J.3
Pomykala, H.4
Yonebayashi, Y.5
Tanabe, S.6
Zeleznik-Le, N.7
Rowley, J.D.8
-
35
-
-
0032533231
-
An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region
-
Strissel, P.L., Strick, R., Rowley, J.D. and Zeleznik-Le, N.J. (1998) An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region. Blood, 92, 3793-3803.
-
(1998)
Blood
, vol.92
, pp. 3793-3803
-
-
Strissel, P.L.1
Strick, R.2
Rowley, J.D.3
Zeleznik-Le, N.J.4
-
36
-
-
0030012114
-
Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors
-
Aplan, P.D., Chervinsky, D.S., Stanulla, M. and Burhans, W.C. (1996) Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors. Blood, 87, 2649-2658.
-
(1996)
Blood
, vol.87
, pp. 2649-2658
-
-
Aplan, P.D.1
Chervinsky, D.S.2
Stanulla, M.3
Burhans, W.C.4
-
37
-
-
0030875222
-
Infant leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias
-
Cimino, G., Rapanotti, M.C., Biondi, A., Elia, L., Lo Coco, F., Price, C., Rossi, V., Rivolta, A., Canaani, E., Croce, C.M. et al (1997) Infant leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias. Cancer Res., 57, 2879-2883.
-
(1997)
Cancer Res.
, vol.57
, pp. 2879-2883
-
-
Cimino, G.1
Rapanotti, M.C.2
Biondi, A.3
Elia, L.4
Lo Coco, F.5
Price, C.6
Rossi, V.7
Rivolta, A.8
Canaani, E.9
Croce, C.M.10
-
38
-
-
0026842288
-
Scaffold-associated regions: Cis-acting determinants of chromatin structural loops and functional domains
-
Laemmli, U.K., Kas, E., Poljak, L. and Adachi, Y. (1992) Scaffold-associated regions: cis-acting determinants of chromatin structural loops and functional domains. Curr. Opin. Genet. Dev., 2, 275-285.
-
(1992)
Curr. Opin. Genet. Dev.
, vol.2
, pp. 275-285
-
-
Laemmli, U.K.1
Kas, E.2
Poljak, L.3
Adachi, Y.4
-
39
-
-
0028289026
-
Metaphase chromosome structure: Bands arise from a differential folding path of the highly AT-rich scaffold
-
Saitoh, Y. and Laemmli, U.K. (1994) Metaphase chromosome structure: Bands arise from a differential folding path of the highly AT-rich scaffold. Cell, 76, 609-622.
-
(1994)
Cell
, vol.76
, pp. 609-622
-
-
Saitoh, Y.1
Laemmli, U.K.2
-
40
-
-
0029610541
-
Chromatin domains and prediction of MAR sequences
-
Bouilikas, T. (1995) Chromatin domains and prediction of MAR sequences. Int. Rev. Cytol., 162A, 279-388.
-
(1995)
Int. Rev. Cytol.
, vol.162 A
, pp. 279-388
-
-
Bouilikas, T.1
-
41
-
-
0021675784
-
Organization of the higher-order chromatin loop: Specific DNA attachment sites on nuclear scaffold
-
Mirkovitch, J., Mirault, M. and Laemmli, U.K. (1984) Organization of the higher-order chromatin loop: Specific DNA attachment sites on nuclear scaffold. Cell, 39, 223-232.
-
(1984)
Cell
, vol.39
, pp. 223-232
-
-
Mirkovitch, J.1
Mirault, M.2
Laemmli, U.K.3
-
42
-
-
0023792796
-
Chromatin domain surrounding the human interferon-beta gene as defined by scaffold-attached regions
-
Bode, J. and Maass, K. (1988) Chromatin domain surrounding the human interferon-beta gene as defined by scaffold-attached regions. Biochemistry, 27, 4706-4011.
-
(1988)
Biochemistry
, vol.27
, pp. 4706-14011
-
-
Bode, J.1
Maass, K.2
-
43
-
-
0023969306
-
The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain
-
Phi-Van, L. and Stratling, W.H. (1988) The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain. EMBO J., 3, 655-664.
-
(1988)
EMBO J.
, vol.3
, pp. 655-664
-
-
Phi-Van, L.1
Stratling, W.H.2
-
44
-
-
0032518532
-
Scaffold associated regions in the human type I interferon gene cluster on the short arm of chromosome 9
-
Strissel, P.L., Dann, H.A., Pomykala, H.M., Diaz, M.O., Rowley, J.D. and Olopade, O.I. (1998) Scaffold associated regions in the human type I interferon gene cluster on the short arm of chromosome 9. Genomics, 47, 217-229.
-
(1998)
Genomics
, vol.47
, pp. 217-229
-
-
Strissel, P.L.1
Dann, H.A.2
Pomykala, H.M.3
Diaz, M.O.4
Rowley, J.D.5
Olopade, O.I.6
-
45
-
-
0022553738
-
Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites
-
Cockerill, P.N. and Garrard, W.T. (1986) Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites. Cell, 44, 273-282.
-
(1986)
Cell
, vol.44
, pp. 273-282
-
-
Cockerill, P.N.1
Garrard, W.T.2
-
46
-
-
0029739520
-
Scaffold attachment sites in centromeric associated DNA
-
Strissel, P.L., Espinosa III, R., Rowley, J.D. and Swift, H. (1996) Scaffold attachment sites in centromeric associated DNA. Chromosoma, 105, 122-133.
-
(1996)
Chromosoma
, vol.105
, pp. 122-133
-
-
Strissel, P.L.1
Espinosa R. III2
Rowley, J.D.3
Swift, H.4
-
47
-
-
0024295412
-
Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold
-
Amati, B.B. and Gasser, S.M. (1988) Chromosomal ARS and CEN elements bind specifically to the yeast nuclear scaffold. Cell, 54, 967-978.
-
(1988)
Cell
, vol.54
, pp. 967-978
-
-
Amati, B.B.1
Gasser, S.M.2
-
48
-
-
0026541384
-
Human telomeres are attached to the nuclear matrix
-
de Lange, T. (1992) Human telomeres are attached to the nuclear matrix. EMBO J., 11, 717-724.
-
(1992)
EMBO J.
, vol.11
, pp. 717-724
-
-
De Lange, T.1
-
49
-
-
0029584719
-
Scaffold/Matrix-attached regions: Structural properties creating transcriptionally active loci
-
Bode, J., Schlake, T., Rios-Ramirez, M., Mielke, C., Stengert, M., Kay, V. and Klehr-Wirth, D. (1995) Scaffold/Matrix-attached regions: Structural properties creating transcriptionally active loci. Int. Rev. Cytol., 162A, 389-454.
-
(1995)
Int. Rev. Cytol.
, vol.162 A
, pp. 389-454
-
-
Bode, J.1
Schlake, T.2
Rios-Ramirez, M.3
Mielke, C.4
Stengert, M.5
Kay, V.6
Klehr-Wirth, D.7
-
50
-
-
0029561761
-
SARs are cis DNA elements of chromosome dynamics: Synthesis of a SAR repressor protein
-
Strick, R. and Laemmli, U.K. (1995) SARs are cis DNA elements of chromosome dynamics: Synthesis of a SAR repressor protein. Cell, 83, 1137-1148.
-
(1995)
Cell
, vol.83
, pp. 1137-1148
-
-
Strick, R.1
Laemmli, U.K.2
-
51
-
-
0028270307
-
Elements regulating somatic hypermutation of an immunoglobulin kappa gene: Critical role for the intron enhancer/ matrix attachment region
-
Betz, A.G., Milstein, C., Gonzalez-Fernandez, A., Pannell, R., Larson, T. and Neuberger, M.S. (1994) Elements regulating somatic hypermutation of an immunoglobulin kappa gene: critical role for the intron enhancer/ matrix attachment region. Cell, 77, 239-248.
-
(1994)
Cell
, vol.77
, pp. 239-248
-
-
Betz, A.G.1
Milstein, C.2
Gonzalez-Fernandez, A.3
Pannell, R.4
Larson, T.5
Neuberger, M.S.6
-
52
-
-
0027963309
-
Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions
-
Forrester, W.C., van Genderen, C., Jenuwein, T. and Grosschedl, R. (1994) Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions. Science, 265, 1221-1225.
-
(1994)
Science
, vol.265
, pp. 1221-1225
-
-
Forrester, W.C.1
Van Genderen, C.2
Jenuwein, T.3
Grosschedl, R.4
-
53
-
-
0031030535
-
Extension of chromatin accessibility by nuclear matrix attachment regions
-
Jenuwein, T., Forrester, W.C., Fernandez-Herrero, L.A., Laible, G., Dull, M. and Grosschedl, R. (1997) Extension of chromatin accessibility by nuclear matrix attachment regions. Nature, 385, 269-272.
-
(1997)
Nature
, vol.385
, pp. 269-272
-
-
Jenuwein, T.1
Forrester, W.C.2
Fernandez-Herrero, L.A.3
Laible, G.4
Dull, M.5
Grosschedl, R.6
-
54
-
-
0025966711
-
Chromosome assembly in vitro: Topoisomerase II is required for condensation
-
Adachi, Y., Luke, M. and Laemmli, U.K. (1991) Chromosome assembly in vitro: Topoisomerase II is required for condensation. Cell, 64, 137-148.
-
(1991)
Cell
, vol.64
, pp. 137-148
-
-
Adachi, Y.1
Luke, M.2
Laemmli, U.K.3
-
55
-
-
0028046036
-
Structure and function of type II DNA topoisomerases
-
Watt, P.M and Hickson, I.D. (1994) Structure and function of type II DNA topoisomerases. Biochem. J., 303, 681-695.
-
(1994)
Biochem. J.
, vol.303
, pp. 681-695
-
-
Watt, P.M.1
Hickson, I.D.2
-
56
-
-
0023902435
-
A consensus sequence for cleavage by vertebrate DNA topoisomerase II
-
Spitzner, J.R. and Muller, M.T. (1988) A consensus sequence for cleavage by vertebrate DNA topoisomerase II. Nucleic Acids Res., 16, 5533-5556.
-
(1988)
Nucleic Acids Res.
, vol.16
, pp. 5533-5556
-
-
Spitzner, J.R.1
Muller, M.T.2
-
57
-
-
0344413285
-
Dysfunction of chromosomal loop attachment sites: Illegitimate recombination linked to matrix association regions and lopoisomerase II
-
Sperry, A.O., Blasquez, V.C. and Garrard, W.T. (1989) Dysfunction of chromosomal loop attachment sites: Illegitimate recombination linked to matrix association regions and lopoisomerase II. Proc. Natl Acad. Sci. USA, 86, 5497-5501.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 5497-5501
-
-
Sperry, A.O.1
Blasquez, V.C.2
Garrard, W.T.3
-
58
-
-
0027396087
-
A model for chromatin opening: Stimulation of topoisomerase II and restriction enzyme cleavage of chromatin by distamycin
-
Kas, E., Poljak, L., Adachi, Y. and Laemmli, U.K. (1993) A model for chromatin opening: stimulation of topoisomerase II and restriction enzyme cleavage of chromatin by distamycin. EMBO J., 12, 115-126.
-
(1993)
EMBO J.
, vol.12
, pp. 115-126
-
-
Kas, E.1
Poljak, L.2
Adachi, Y.3
Laemmli, U.K.4
-
59
-
-
0033214044
-
Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions
-
Strumberg, D., Nitiss, J.L., Dong, J., Kohn, K.W. and Pommier, Y. (1999) Molecular analysis of yeast and human type II topoisomerases. Enzyme-DNA and drug interactions. J. Biol. Chem., 274, 28246-28255.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28246-28255
-
-
Strumberg, D.1
Nitiss, J.L.2
Dong, J.3
Kohn, K.W.4
Pommier, Y.5
-
60
-
-
0032491903
-
DNA topoisomerase II cleavage of telomeres in vitro and in vivo
-
Yoon, H.J., Choi, I.Y., Kang, M.R., Kim, S.S., Muller, M.T., Spitzner, J.R. and Chung, I.K. (1998) DNA topoisomerase II cleavage of telomeres in vitro and in vivo. Biochim. Biophys. Acta, 1395, 110-120.
-
(1998)
Biochim. Biophys. Acta
, vol.1395
, pp. 110-120
-
-
Yoon, H.J.1
Choi, I.Y.2
Kang, M.R.3
Kim, S.S.4
Muller, M.T.5
Spitzner, J.R.6
Chung, I.K.7
-
61
-
-
0033168394
-
Functional analysis of DNA sequences located within a cluster of DNase I hypersensitive sites colocalizing with a MAR element at the upstream border of the chicken alpha-globin gene domain
-
Razin, S.V., Shen, K., Ioudinkova, E. and Scherrer, K. (1999) Functional analysis of DNA sequences located within a cluster of DNase I hypersensitive sites colocalizing with a MAR element at the upstream border of the chicken alpha-globin gene domain. J. Cell. Biochem., 74, 38-49.
-
(1999)
J. Cell. Biochem.
, vol.74
, pp. 38-49
-
-
Razin, S.V.1
Shen, K.2
Ioudinkova, E.3
Scherrer, K.4
-
62
-
-
0033215297
-
Identification and characterization of nuclear matrix-attachment regions in the human serpin gene cluster at 14q32
-
Rollini, P., Namciu, S.J., Marsden, M.D. and Fournier, R.E.K. (1999) Identification and characterization of nuclear matrix-attachment regions in the human serpin gene cluster at 14q32. Nucleic Acids Res., 27, 3779-3791.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 3779-3791
-
-
Rollini, P.1
Namciu, S.J.2
Marsden, M.D.3
Fournier, R.E.K.4
-
63
-
-
0027435071
-
Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia
-
Negrini, M., Felix, C.A., Martin, C., Lange, B.J., Nakamura, T., Canaani, E. and Croce, C.M. (1993) Potential topoisomerase II DNA-binding sites at the breakpoints of a t(9;11) chromosome translocation in acute myeloid leukemia. Cancer Res., 53, 4489-4492.
-
(1993)
Cancer Res.
, vol.53
, pp. 4489-4492
-
-
Negrini, M.1
Felix, C.A.2
Martin, C.3
Lange, B.J.4
Nakamura, T.5
Canaani, E.6
Croce, C.M.7
-
64
-
-
0030886240
-
Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia
-
Super, H.G., Strissel, P.L., Sobulo, O.M., Burian, D., Reshmi, S.C., Roe, B., Zeleznik-Le, N.J., Rowley, J.D. and Diaz, M.O. (1997) Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia. Genes Chromosomes Cancer, 20, 185-195.
-
(1997)
Genes Chromosomes Cancer
, vol.20
, pp. 185-195
-
-
Super, H.G.1
Strissel, P.L.2
Sobulo, O.M.3
Burian, D.4
Reshmi, S.C.5
Roe, B.6
Zeleznik-Le, N.J.7
Rowley, J.D.8
Diaz, M.O.9
-
65
-
-
0024353277
-
Evidence for the reversibility of cellular DNA lesion induced by mammalian topoisomerase II poisons
-
Hsiang, Y. H. and Liu, L.F. (1989) Evidence for the reversibility of cellular DNA lesion induced by mammalian topoisomerase II poisons. J. Biol. Chem., 264, 9713-9715.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 9713-9715
-
-
Hsiang, Y.H.1
Liu, L.F.2
-
66
-
-
0029922061
-
Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: Heterogeneous localization and reversibility
-
Borgnetto, M.E., Zunino, F., Tinelli, S., Kas, E. and Capranico, G. (1996) Drug-specific sites of topoisomerase II DNA cleavage in Drosophila chromatin: heterogeneous localization and reversibility. Cancer Res., 56, 1855-1862.
-
(1996)
Cancer Res.
, vol.56
, pp. 1855-1862
-
-
Borgnetto, M.E.1
Zunino, F.2
Tinelli, S.3
Kas, E.4
Capranico, G.5
-
67
-
-
0025936208
-
Chromatin structure, not DNA sequence specificity, is the primary determinant of topoisomerase II sites of action in vivo
-
Udvardy, A. and Schedl, P. (1991) Chromatin structure, not DNA sequence specificity, is the primary determinant of topoisomerase II sites of action in vivo. Mol. Cell. Biol, 11, 4973-4984.
-
(1991)
Mol. Cell. Biol
, vol.11
, pp. 4973-4984
-
-
Udvardy, A.1
Schedl, P.2
-
68
-
-
0028325365
-
Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells
-
Ritke, M.K., Roberts, D., Allan, W.P., Raymond, J., Bergoltz, V.V. and Yalowich, J.C. (1994) Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells. Br. J. Cancer, 69, 687-697.
-
(1994)
Br. J. Cancer
, vol.69
, pp. 687-697
-
-
Ritke, M.K.1
Roberts, D.2
Allan, W.P.3
Raymond, J.4
Bergoltz, V.V.5
Yalowich, J.C.6
-
69
-
-
0031011855
-
DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis
-
Stanulla, M., Wang, J., Chervinsky, D.S., Thandla, S. and Aplan, P.D. (1997) DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis. Mol. Cell. Biol., 17, 4070-4079.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4070-4079
-
-
Stanulla, M.1
Wang, J.2
Chervinsky, D.S.3
Thandla, S.4
Aplan, P.D.5
-
70
-
-
0342927819
-
Stable DNA unwinding, not 'breathing,' accounts for single-strand-specific nuclease hypersensitivity of specific A+T-rich sequences
-
Kowalski, D., Natale, D.A. and Eddy, M.J. (1988) Stable DNA unwinding, not 'breathing,' accounts for single-strand-specific nuclease hypersensitivity of specific A+T-rich sequences. Proc. Natl Acad. Sci. USA, 85, 9464-9468.
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 9464-9468
-
-
Kowalski, D.1
Natale, D.A.2
Eddy, M.J.3
-
71
-
-
0026597313
-
Biological significance of unwinding capability of nuclear matrix-associating DNAs
-
Bode, J., Kohwi, Y., Dickinson, L., Joh, T., Klehr, D., Mielke, C. and Kohwi-Shigematsu, T. (1992) Biological significance of unwinding capability of nuclear matrix-associating DNAs. Science, 255, 195-197.
-
(1992)
Science
, vol.255
, pp. 195-197
-
-
Bode, J.1
Kohwi, Y.2
Dickinson, L.3
Joh, T.4
Klehr, D.5
Mielke, C.6
Kohwi-Shigematsu, T.7
-
72
-
-
0021792433
-
Correlations between intercalator-induced DNA strand breaks and sister chromatid exchanges, mutations, and cytotoxicity in Chinese hamster cells
-
Pommier, Y., Zwelling, L.A., Kao-Shan, C.S., Whang-Peng, J. and Bradley, M.O. (1985) Correlations between intercalator-induced DNA strand breaks and sister chromatid exchanges, mutations, and cytotoxicity in Chinese hamster cells. Cancer Res., 45, 3143-3149.
-
(1985)
Cancer Res.
, vol.45
, pp. 3143-3149
-
-
Pommier, Y.1
Zwelling, L.A.2
Kao-Shan, C.S.3
Whang-Peng, J.4
Bradley, M.O.5
-
73
-
-
0024121519
-
Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro
-
Bae, Y.S., Kawasaki, I., Ikeda, H. and Liu, L.F. (1988) Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro. Proc. Natl Acad. Sci USA, 85, 2076-2080.
-
(1988)
Proc. Natl Acad. Sci USA
, vol.85
, pp. 2076-2080
-
-
Bae, Y.S.1
Kawasaki, I.2
Ikeda, H.3
Liu, L.F.4
-
74
-
-
0026694614
-
Intrinsic intermolecular DNA ligation activity of eukaryotic topoisomerase II. Potential roles in recombination
-
Gale, K.C. and Osheroff, N. (1992) Intrinsic intermolecular DNA ligation activity of eukaryotic topoisomerase II. Potential roles in recombination. J. Biol. Chem., 267, 12090-12097.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12090-12097
-
-
Gale, K.C.1
Osheroff, N.2
-
75
-
-
0030784935
-
A precise interchromosomal reciprocal exchange between hot spots for cleavable complex formation by topoisomerase II in amsacrine-treated Chinese hamster ovary cells
-
Zhou, R.H., Wang, P., Zou, Y., Jackson-Cook, C.K. and Povirk, L.F. (1997) A precise interchromosomal reciprocal exchange between hot spots for cleavable complex formation by topoisomerase II in amsacrine-treated Chinese hamster ovary cells. Cancer Res., 57, 4699-4702.
-
(1997)
Cancer Res.
, vol.57
, pp. 4699-4702
-
-
Zhou, R.H.1
Wang, P.2
Zou, Y.3
Jackson-Cook, C.K.4
Povirk, L.F.5
-
76
-
-
0033587740
-
The kinetoplast structure-specific endonuclease I is related to the 5′ exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase beta during replication
-
Engel, M.L. and Ray, D.S. (1999) The kinetoplast structure-specific endonuclease I is related to the 5′ exo/endonuclease domain of bacterial DNA polymerase I and colocalizes with the kinetoplast topoisomerase II and DNA polymerase beta during replication. Proc. Natl Acad. Sci. USA, 96, 8455-8460.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 8455-8460
-
-
Engel, M.L.1
Ray, D.S.2
-
77
-
-
0032506701
-
Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation 1(4;11): The DNA damage-repair model of translocation
-
Reichel, M., Gillert, E., Nilson, I., Siegler, G., Greil, J., Fey, G.H. and Marschalek. R. (1998) Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation 1(4;11): the DNA damage-repair model of translocation. Oncogene, 17, 3035-3044.
-
(1998)
Oncogene
, vol.17
, pp. 3035-3044
-
-
Reichel, M.1
Gillert, E.2
Nilson, I.3
Siegler, G.4
Greil, J.5
Fey, G.H.6
Marschalek, R.7
-
78
-
-
84941143640
-
Shotgun cloning as the strategy of choice to generate template for high throughput dideoxynucleotide sequencing
-
Adams, M.D., Fields C. and Venter C. (eds), Academic Press, London
-
Bodenteich, A., Chissoe, S., Wang, Y.F. and Roe, B.A. (1994) Shotgun cloning as the strategy of choice to generate template for high throughput dideoxynucleotide sequencing. In Adams, M.D., Fields C. and Venter C. (eds), Automated DNA Sequencing and Analysis Techniques. Academic Press, London, pp. 42-50.
-
(1994)
Automated DNA Sequencing and Analysis Techniques
, pp. 42-50
-
-
Bodenteich, A.1
Chissoe, S.2
Wang, Y.F.3
Roe, B.A.4
|