Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia

Biochemical and Biophysical Research Communications

Volumn 399, Issue 1, 2010, Pages 66-71

  Azarova, Anna M ^a   Lin, Ren Kuo ^a   Tsai, Yuan Chin ^a   Liu, Leroy F ^a   Lin, Chao Po ^a   Lyu, Yi Lisa ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Genistein; Infant leukemia; MLL translocation; Proteasome; Topoisomerase IIbeta

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; GENISTEIN; HISTONE H2AX; PROTEASOME;

ANIMAL CELL; ARTICLE; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; DNA CLEAVAGE; DNA SEQUENCE; DNA STRAND BREAKAGE; EMBRYO; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME REGULATION; FIBROBLAST; IMMUNOBLOTTING; IN VITRO STUDY; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA TOPOISOMERASES, TYPE I; GENISTEIN; HUMANS; INFANT; ISOENZYMES; LEUKEMIA, MYELOID, ACUTE; MICE; PROTEASOME ENDOPEPTIDASE COMPLEX; RECOMBINATION, GENETIC;

EID: 77955562548     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.07.043     Document Type: Article

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