Analysis of t(15;17) chromosomal breakpoint sequences in therapy-related versus de novo acute promyelocytic leukemia: Association of DNA breaks with specific DNA motifs at PML and RARA loci

Genes Chromosomes and Cancer

Volumn 49, Issue 8, 2010, Pages 726-732

  Hasan, Syed Khizer ^a,b   Ottone, Tiziana ^a,b   Schlenk, Richard F ^c   Xiao, Yuanyuan ^d   Wiemels, Joseph L ^d   Mitra, Maria Enza ^e   Bernasconi, Paolo ^f   Raimondo, Francesco Di ^g   Stanghellini, Maria Teresa Lupo ^h   Marco, Pepa ⁱ   Mays, Ashley N ^j   Döhner, Hartmut ^c   Sanz, Miguel A ^k   Amadori, Sergio ^a   Grimwade, David ^j   Lo Coco, Francesco ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITY HOSPITAL ULM   (Germany)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF PALERMO   (Italy)

^f UNIVERSITY OF PAVIA   (Italy)

^g UNIVERSITY OF CATANIA   (Italy)

^h SAN RAFFAELE HOSPITAL   (Italy)

ⁱ HOSPITAL GENERAL DE CASTELLÓN   (Spain)

^j KING'S COLLEGE LONDON   (United Kingdom)

^k HOSPITAL UNIVERSITARIO LA FE   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); MITOXANTRONE; PROMYELOCYTIC LEUKEMIA PROTEIN;

ADULT; AGED; ARTICLE; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; FEMALE; GENE LOCUS; HUMAN; INTRON; MALE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

ADULT; AGED; ANTINEOPLASTIC AGENTS; CHROMOSOME BREAKPOINTS; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 17; DNA, NEOPLASM; FEMALE; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; MIDDLE AGED; MITOXANTRONE; NUCLEAR PROTEINS; RECEPTORS, RETINOIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; TUMOR SUPPRESSOR PROTEINS; YOUNG ADULT;

EID: 77953522671     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20783     Document Type: Article

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