Presteady state kinetic investigation of the incorporation of anti-hepatitis B nucleotide analogues catalyzed by noncanonical human DNA polymerases

Chemical Research in Toxicology

Volumn 25, Issue 1, 2012, Pages 225-233

  Brown, Jessica A ^a   Pack, Lindsey R ^a   Fowler, Jason D ^a   Suo, Zucai ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ANTIVIRUS AGENT; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE ETA; DNA DIRECTED DNA POLYMERASE GAMMA; DNA DIRECTED DNA POLYMERASE IOTA; DNA DIRECTED DNA POLYMERASE KAPPA; DNA DIRECTED DNA POLYMERASE LAMBDA; DNA POLYMERASE; DNA POLYMERASE REV1; ENTECAVIR; LAMIVUDINE; NUCLEOTIDE DERIVATIVE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TELBIVUDINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DNA SEQUENCE; DRUG DNA INTERACTION; DRUG STRUCTURE; ENZYME KINETICS; ENZYME SPECIFICITY; HEPATITIS B; STEADY STATE;

ANTIVIRAL AGENTS; CATALYSIS; DNA; DNA-DIRECTED DNA POLYMERASE; HEPATITIS B; HUMANS; KINETICS; NUCLEOSIDES; NUCLEOTIDES; PURINES;

HEPATITIS B VIRUS;

EID: 84862910201     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200458s     Document Type: Article

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