Insights into the Molecular Mechanism of Mitochondrial Toxicity by AIDS Drugs

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 23832-23837

  Feng, Joy Y ^a,c   Johnson, Allison A ^b   Johnson, Kenneth A ^b   Anderson, Karen S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c Triangle Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DRUG THERAPY; ENZYMES; TOXICITY;

TOXIC INHIBITORS;

BIOCHEMISTRY;

2',3' DIDEOXY 3' THIACYTIDINE 5' TRIPHOSPHATE; ANTIVIRUS AGENT; CYTOSINE DERIVATIVE; DEOXYCYTIDINE; DIDANOSINE; DNA DIRECTED DNA POLYMERASE GAMMA; DNA POLYMERASE; EXONUCLEASE; LAMIVUDINE; NUCLEOSIDE DERIVATIVE; PRIMER DNA; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE; 2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYTIDINE TRIPHOSPHATE; DEOXYCYTIDINE PHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DNA; DNA DIRECTED DNA POLYMERASE; DRUG DERIVATIVE; EXODEOXYRIBONUCLEASE; LAMIVUDINE TRIPHOSPHATE; MITOCHONDRIAL DNA; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CORRELATION ANALYSIS; DNA BINDING; DNA STRUCTURE; DRUG STRUCTURE; DRUG TOLERABILITY; ENZYME BINDING; HUMAN; INHIBITION KINETICS; ISOMERISM; LONG TERM CARE; MITOCHONDRIAL MYOPATHY; MITOCHONDRIAL RESPIRATION; MOLECULAR MECHANICS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; BIOSYNTHESIS; COMPARATIVE STUDY; DNA REPLICATION; DRUG ANTAGONISM; DRUG EFFECT; KINETICS; METABOLISM; MITOCHONDRION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTI-HIV AGENTS; CYTIDINE TRIPHOSPHATE; DEOXYCYTOSINE NUCLEOTIDES; DNA; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; HUMANS; KINETICS; LAMIVUDINE; MITOCHONDRIA; REVERSE TRANSCRIPTASE INHIBITORS; ZALCITABINE;

EID: 0035968250     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101156200     Document Type: Article

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