Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-phosphonylmethoxypropyl)adenine

Journal of Biological Chemistry

Volumn 273, Issue 42, 1998, Pages 27250-27258

  Suo, Zucai ^a,b   Johnson, Kenneth A ^a,c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYCLIC NUCLEOSIDE; DIDANOSINE; LAMIVUDINE; RNA DIRECTED DNA POLYMERASE; STAVUDINE; TENOFOVIR; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DNA INTEGRATION; DNA RNA HYBRIDIZATION; DRUG DNA BINDING; DRUG SELECTIVITY; DRUG TARGETING; DRUG TOLERANCE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; STEADY STATE; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS MUTATION; VIRUS REPLICATION;

ADENINE; ANIMALS; ANTI-HIV AGENTS; DEOXYADENINE NUCLEOTIDES; DNA POLYMERASE BETA; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; MODELS, CHEMICAL; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; RATS; REVERSE TRANSCRIPTASE INHIBITORS; RNA, VIRAL;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032538456     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.42.27250     Document Type: Article

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