Pre-steady-state kinetic studies of the fidelity and mechanism of polymerization catalyzed by truncated human DNA polymerase λ

Biochemistry

Volumn 43, Issue 21, 2004, Pages 6751-6762

  Fiala, Kevin A ^a   Abdel Gawad, Wissam ^a   Suo, Zucai ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; DNA; DNA SEQUENCES; POLYMERIZATION; RATE CONSTANTS;

BIOCHEMICAL PATHWAYS; DNA POLYMERASE;

ENZYME KINETICS;

DNA POLYMERASE; DNA POLYMERASE LAMBDA; DOUBLE STRANDED DNA; GUANOSINE TRIPHOSPHATE; NUCLEOTIDE; PROLINE; THYMINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; DISSOCIATION; DNA STRAND BREAKAGE; DNA TEMPLATE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; EXCISION REPAIR; MAMMAL; MISMATCH REPAIR; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; STEADY STATE;

BASE PAIR MISMATCH; CATALYSIS; DEOXYGUANINE NUCLEOTIDES; DNA; DNA POLYMERASE BETA; DNA REPAIR; HUMANS; KINETICS; NUCLEOTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; THYMINE; TIME FACTORS;

MAMMALIA;

EID: 2542571187     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049975c     Document Type: Article

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