Structural basis of error-prone replication and stalling at a thymine base by human DNA polymerase

EMBO Journal

Volumn 28, Issue 11, 2009, Pages 1644-1654

  Kirouac, Kevin N ^a   Ling, Hong ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Incorporation specificity; Mutagenesis; Pol i; Translesion synthesis; Y family DNA polymerase

Indexed keywords

DEOXYGUANOSINE TRIPHOSPHATE; DNA POLYMERASE; DNA POLYMERASE IOTA; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA REPLICATION; HYDROGEN BOND; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BASE PAIRING; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; SEQUENCE ALIGNMENT; THYMINE;

EID: 67349236998     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.122     Document Type: Article

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