The intracellular activation of lamivudine (3TC) and determination of 2′-deoxycytidine-5′-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells

British Journal of Clinical Pharmacology

Volumn 50, Issue 6, 2000, Pages 597-604

  Kewn, Stephen ^a   Hoggard, Patrick G ^a   Sean, ^a   Sales, D ^a   Mark, ^a   Johnson, A ^a,b   Back, David J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

3TC; dCTP; Drug interactions; HepG2 cells; Phosphorylation

Indexed keywords

ADEFOVIR DIPIVOXIL; DEOXYCYTIDINE TRIPHOSPHATE; FLUDARABINE; FOSCARNET; GANCICLOVIR; HYDROXYUREA; LAMIVUDINE; LOBUCAVIR; METHOTREXATE; PENCICLOVIR;

ARTICLE; CELL LINE; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVATION; DRUG DETERMINATION; DRUG POTENTIATION; HUMAN; HUMAN CELL; PHOSPHORYLATION; PRIORITY JOURNAL;

ANTI-HIV AGENTS; CELL SURVIVAL; CYTIDINE TRIPHOSPHATE; DEOXYCYTOSINE NUCLEOTIDES; DRUG INTERACTIONS; HUMANS; HYDROXYUREA; LAMIVUDINE; METHOTREXATE; PHOSPHORYLATION; TUMOR CELLS, CULTURED; VIDARABINE;

EID: 0034531827     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2000.00302.x     Document Type: Article

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