Tenofovir diphosphate is a poor substrate and a weak inhibitor of rat DNA polymerases α, δ, and ε*

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 5, 2002, Pages 1610-1613

  Birkuš, Gabriel ^a   Hájek, Miroslav ^a   Kramata, Pavel ^a   Votruba, Ivan ^a   Holý, Antonín ^a   Otová, Berta ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE DERIVATIVE; DEOXYADENOSINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; DNA POLYMERASE; PRODRUG; TENOFOVIR; TENOFOVIR DIPHOSPHATE; TENOFOVIR DISOPROXIL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME INHIBITOR INTERACTION; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENINE; ANIMALS; ANTI-HIV AGENTS; DNA POLYMERASE I; DNA POLYMERASE II; DNA POLYMERASE III; DNA-DIRECTED DNA POLYMERASE; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHONIC ACIDS; RATS; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 0036233759     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.5.1610-1613.2002     Document Type: Article

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