Selectively Guanidinylated Aminoglycosides as Antibiotics

ChemMedChem

Volumn 7, Issue 7, 2012, Pages 1237-1244

  Fair, Richard J ^a   Hensler, Mary E ^a   Thienphrapa, Wdee ^a   Dam, Quang N ^a   Nizet, Victor ^a   Tor, Yitzhak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

A site RNA; Amikacin; Aminoglycosides; Antibiotics; Methicillin resistant Staphylococcus aureus (MRSA)

Indexed keywords

AMIKACIN; AMINE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; APRAMYCIN; GUANIDINE; KANAMYCIN A; NEOMYCIN B NEAMINE; PAROMOMYCIN; RIBOSOME RNA; RNA; TOBRAMYCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL STRAIN; BINDING ASSAY; DRUG POTENCY; DRUG SYNTHESIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; GUANIDINES; MICROBIAL SENSITIVITY TESTS; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84862880731     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201200150     Document Type: Article

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