-
1
-
-
0017852323
-
Comparison of neuromuscular effects and acute toxicity of some aminoglycoside antibiotics
-
Albiero L., Bamonte F., Ongini E., Parravicini L. Comparison of neuromuscular effects and acute toxicity of some aminoglycoside antibiotics. Arch. Int. Pharmacodyn. Thér. 1978, 233:343-350.
-
(1978)
Arch. Int. Pharmacodyn. Thér.
, vol.233
, pp. 343-350
-
-
Albiero, L.1
Bamonte, F.2
Ongini, E.3
Parravicini, L.4
-
3
-
-
53249127377
-
Recent advances in the discovery of hybrid antibacterial agents
-
Barbachyn M.R. Recent advances in the discovery of hybrid antibacterial agents. Annu. Rep. Med. Chem. 2008, 43:281-290.
-
(2008)
Annu. Rep. Med. Chem.
, vol.43
, pp. 281-290
-
-
Barbachyn, M.R.1
-
4
-
-
0035032997
-
Structural basis for selectivity and toxicity of ribosomal antibiotics
-
Bottger E.C., Springer B., Prammananan T., Kidan Y., Sander P. Structural basis for selectivity and toxicity of ribosomal antibiotics. EMBO Rep. 2001, 2:318-323.
-
(2001)
EMBO Rep.
, vol.2
, pp. 318-323
-
-
Bottger, E.C.1
Springer, B.2
Prammananan, T.3
Kidan, Y.4
Sander, P.5
-
5
-
-
34250160226
-
Dual action-based approaches to antibacterial agents
-
Bremner J.B., Ambrus J.I., Samosorn S. Dual action-based approaches to antibacterial agents. Curr. Med. Chem. 2007, 14:1459-1477.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 1459-1477
-
-
Bremner, J.B.1
Ambrus, J.I.2
Samosorn, S.3
-
6
-
-
0034699519
-
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
-
Carter A.P., Clemons W.M., Brodersen D.E., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 2000, 407:340-348.
-
(2000)
Nature
, vol.407
, pp. 340-348
-
-
Carter, A.P.1
Clemons, W.M.2
Brodersen, D.E.3
Morgan-Warren, R.J.4
Wimberly, B.T.5
Ramakrishnan, V.6
-
7
-
-
34247277741
-
Antibiotic interactions that select against resistance
-
Chait R., Craney A., Kishony R. Antibiotic interactions that select against resistance. Nature 2007, 446:668-671.
-
(2007)
Nature
, vol.446
, pp. 668-671
-
-
Chait, R.1
Craney, A.2
Kishony, R.3
-
8
-
-
52949089017
-
Structure-toxicity relationship of aminoglycosides: Correlation of 2'-amine basicity with acute toxicity in pseudo-disaccharide scaffolds
-
Chen L., Hainrichson M., Bourdetsky D., Mor A., Yaron S., Baasov T. Structure-toxicity relationship of aminoglycosides: Correlation of 2'-amine basicity with acute toxicity in pseudo-disaccharide scaffolds. Bioorg. Med. Chem. 2008, 16:8940-8951.
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 8940-8951
-
-
Chen, L.1
Hainrichson, M.2
Bourdetsky, D.3
Mor, A.4
Yaron, S.5
Baasov, T.6
-
9
-
-
77953399146
-
Aminoglycosides: Molecular insights on the recognition of RNA and aminoglycoside mimics
-
Chittapragada M., Roberts S., Ham Y.W. Aminoglycosides: Molecular insights on the recognition of RNA and aminoglycoside mimics. Perspect. Med. Chem. 2009, 3:21-37.
-
(2009)
Perspect. Med. Chem.
, vol.3
, pp. 21-37
-
-
Chittapragada, M.1
Roberts, S.2
Ham, Y.W.3
-
10
-
-
77952601799
-
Discovery of a gene conferring multiple aminoglycoside resistance in Escherichia coli
-
Davis M.A., Baker K.N., Orfe L.H., Shah D., Besser T.E., Call D.R. Discovery of a gene conferring multiple aminoglycoside resistance in Escherichia coli. Antimicrob. Agents Chemother. 2010, 54(6):2666-2669.
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, Issue.6
, pp. 2666-2669
-
-
Davis, M.A.1
Baker, K.N.2
Orfe, L.H.3
Shah, D.4
Besser, T.E.5
Call, D.R.6
-
11
-
-
0021318782
-
Fidelity of the eukaryotic codon-anticodon interaction: Interference by aminoglycoside antibiotics
-
Eustice D.C., Wilhelm J.M. Fidelity of the eukaryotic codon-anticodon interaction: Interference by aminoglycoside antibiotics. Biochemistry 1984, 23:1462-1467.
-
(1984)
Biochemistry
, vol.23
, pp. 1462-1467
-
-
Eustice, D.C.1
Wilhelm, J.M.2
-
13
-
-
22144478634
-
Efficient synthetic inhibitors of anthrax lethal factor
-
Forino M., Johnson S., Wong T.Y., Rozanov D.V., Savinov A.Y., Li W., Fattorusso R., Becattini B., Orry A.J., Jung D., Abagyan R.A., Smith J.W., et al. Efficient synthetic inhibitors of anthrax lethal factor. Proc. Natl. Acad. Sci. USA 2005, 102:9499-9504.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 9499-9504
-
-
Forino, M.1
Johnson, S.2
Wong, T.Y.3
Rozanov, D.V.4
Savinov, A.Y.5
Li, W.6
Fattorusso, R.7
Becattini, B.8
Orry, A.J.9
Jung, D.10
Abagyan, R.A.11
Smith, J.W.12
-
14
-
-
0032571359
-
Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA
-
Fourmy D., Yoshizawa S., Puglisi J.D. Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA. J. Mol. Biol. 1998, 277:333-345.
-
(1998)
J. Mol. Biol.
, vol.277
, pp. 333-345
-
-
Fourmy, D.1
Yoshizawa, S.2
Puglisi, J.D.3
-
15
-
-
27244458194
-
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: Role of the number of rings and positive charges in the specific binding leading to miscoding
-
Francois B., Russell R.J., Murray J.B., Aboul-ela F., Masquida B., Vicens Q., Westhof E. Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: Role of the number of rings and positive charges in the specific binding leading to miscoding. Nucleic Acids Res. 2005, 33:5677-5690.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 5677-5690
-
-
Francois, B.1
Russell, R.J.2
Murray, J.B.3
Aboul-ela, F.4
Masquida, B.5
Vicens, Q.6
Westhof, E.7
-
16
-
-
0142106443
-
A new class of branched aminoglycosides: Pseudo-pentasaccharide derivatives of neomycin B
-
Fridman M., Belakhov V., Yaron S., Baasov T. A new class of branched aminoglycosides: Pseudo-pentasaccharide derivatives of neomycin B. Org. Lett. 2003, 5:3575-3578.
-
(2003)
Org. Lett.
, vol.5
, pp. 3575-3578
-
-
Fridman, M.1
Belakhov, V.2
Yaron, S.3
Baasov, T.4
-
17
-
-
12344323881
-
Dual effect of synthetic aminoglycosides: Antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor
-
Fridman M., Belakhov V., Lee L.V., Liang F.S., Wong C.H., Baasov T. Dual effect of synthetic aminoglycosides: Antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor. Angew. Chem. Int. Ed. Engl. 2005, 44:447-452.
-
(2005)
Angew. Chem. Int. Ed. Engl.
, vol.44
, pp. 447-452
-
-
Fridman, M.1
Belakhov, V.2
Lee, L.V.3
Liang, F.S.4
Wong, C.H.5
Baasov, T.6
-
18
-
-
46449091667
-
Aminoglycoside induced ototoxicity
-
Guthrie O.W. Aminoglycoside induced ototoxicity. Toxicology 2008, 249:91-96.
-
(2008)
Toxicology
, vol.249
, pp. 91-96
-
-
Guthrie, O.W.1
-
19
-
-
24344452466
-
Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives
-
Hainrichson M., Pokrovskaya V., Shallom-Shezifi D., Fridman M., Belakhov V., Shachar D., Yaron S., Baasov T. Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives. Bioorg. Med. Chem. 2005, 13:5797-5807.
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 5797-5807
-
-
Hainrichson, M.1
Pokrovskaya, V.2
Shallom-Shezifi, D.3
Fridman, M.4
Belakhov, V.5
Shachar, D.6
Yaron, S.7
Baasov, T.8
-
20
-
-
33846566731
-
Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa
-
Hainrichson M., Yaniv O., Cherniavsky M., Nudelman I., Shallom-Shezifi D., Yaron S., Baasov T. Overexpression and initial characterization of the chromosomal aminoglycoside 3'-O-phosphotransferase APH(3')-IIb from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 2007, 51:774-776.
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 774-776
-
-
Hainrichson, M.1
Yaniv, O.2
Cherniavsky, M.3
Nudelman, I.4
Shallom-Shezifi, D.5
Yaron, S.6
Baasov, T.7
-
21
-
-
37849013607
-
Designer aminoglycosides: The race to develop improved antibiotics and compounds for the treatment of human genetic diseases
-
Hainrichson M., Nudelman I., Baasov T. Designer aminoglycosides: The race to develop improved antibiotics and compounds for the treatment of human genetic diseases. Org. Biomol. Chem. 2008, 6:227-239.
-
(2008)
Org. Biomol. Chem.
, vol.6
, pp. 227-239
-
-
Hainrichson, M.1
Nudelman, I.2
Baasov, T.3
-
22
-
-
34547093657
-
Aminoglycoside antibiotics: Old drugs and new therapeutic approaches
-
Hermann T. Aminoglycoside antibiotics: Old drugs and new therapeutic approaches. Cell. Mol. Life Sci. 2007, 64:1841-1852.
-
(2007)
Cell. Mol. Life Sci.
, vol.64
, pp. 1841-1852
-
-
Hermann, T.1
-
23
-
-
58549117857
-
Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity
-
Hobbie S.N., Akshay S., Kalapala S.K., Bruell C.M., Shcherbakov D., Bottger E.C. Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity. Proc. Natl. Acad. Sci. USA 2008, 105:20888-20893.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20888-20893
-
-
Hobbie, S.N.1
Akshay, S.2
Kalapala, S.K.3
Bruell, C.M.4
Shcherbakov, D.5
Bottger, E.C.6
-
24
-
-
42149087058
-
Mitochondrial deafness alleles confer misreading of the genetic code
-
Hobbie S.N., Bruell C.M., Akshay S., Kalapala S.K., Shcherbakov D., Bottger E.C. Mitochondrial deafness alleles confer misreading of the genetic code. Proc. Natl. Acad. Sci. USA 2008, 105:3244-3249.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3244-3249
-
-
Hobbie, S.N.1
Bruell, C.M.2
Akshay, S.3
Kalapala, S.K.4
Shcherbakov, D.5
Bottger, E.C.6
-
25
-
-
0033854425
-
Sequence specificity of aminoglycoside-induced stop condon readthrough: Potential implications for treatment of Duchenne muscular dystrophy
-
Howard M.T., Shirts B.H., Petros L.M., Flanigan K.M., Gesteland R.F., Atkins J.F. Sequence specificity of aminoglycoside-induced stop condon readthrough: Potential implications for treatment of Duchenne muscular dystrophy. Ann. Neurol. 2000, 48:164-169.
-
(2000)
Ann. Neurol.
, vol.48
, pp. 164-169
-
-
Howard, M.T.1
Shirts, B.H.2
Petros, L.M.3
Flanigan, K.M.4
Gesteland, R.F.5
Atkins, J.F.6
-
26
-
-
1442353747
-
Readthrough of dystrophin stop codon mutations induced by aminoglycosides
-
Howard M.T., Anderson C.B., Fass U., Khatri S., Gesteland R.F., Atkins J.F., Flanigan K.M. Readthrough of dystrophin stop codon mutations induced by aminoglycosides. Ann. Neurol. 2004, 55:422-426.
-
(2004)
Ann. Neurol.
, vol.55
, pp. 422-426
-
-
Howard, M.T.1
Anderson, C.B.2
Fass, U.3
Khatri, S.4
Gesteland, R.F.5
Atkins, J.F.6
Flanigan, K.M.7
-
27
-
-
8144225651
-
Characterization of a bifunctional aminoglycoside-modifying enzyme with novel substrate specificity and its gene from a clinical isolate of methicillin-resistant Staphylococcus aureus with high arbekacin resistance
-
Ishino K., Ishikawa J., Ikeda Y., Hotta K. Characterization of a bifunctional aminoglycoside-modifying enzyme with novel substrate specificity and its gene from a clinical isolate of methicillin-resistant Staphylococcus aureus with high arbekacin resistance. J. Antibiot. 2004, 57:679-686.
-
(2004)
J. Antibiot.
, vol.57
, pp. 679-686
-
-
Ishino, K.1
Ishikawa, J.2
Ikeda, Y.3
Hotta, K.4
-
28
-
-
33644547013
-
Molecular understanding of aminoglycoside action and resistance
-
Jana S., Deb J.K. Molecular understanding of aminoglycoside action and resistance. Appl. Microbiol. Biotechnol. 2006, 70:140-150.
-
(2006)
Appl. Microbiol. Biotechnol.
, vol.70
, pp. 140-150
-
-
Jana, S.1
Deb, J.K.2
-
29
-
-
31944443056
-
Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity
-
Kaul M., Barbieri C.M., Pilch D.S. Aminoglycoside-induced reduction in nucleotide mobility at the ribosomal RNA A-site as a potentially key determinant of antibacterial activity. J. Am. Chem. Soc. 2006, 128:1261-1271.
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 1261-1271
-
-
Kaul, M.1
Barbieri, C.M.2
Pilch, D.S.3
-
30
-
-
33644748200
-
Aminoglycosides as potential pharmacogenetic agents in the treatment of Hailey-Hailey disease
-
Kellermayer R., Szigeti R., Keeling K.M., Bedekovics T., Bedwell D.M. Aminoglycosides as potential pharmacogenetic agents in the treatment of Hailey-Hailey disease. J. Invest. Dermatol. 2006, 126:229-231.
-
(2006)
J. Invest. Dermatol.
, vol.126
, pp. 229-231
-
-
Kellermayer, R.1
Szigeti, R.2
Keeling, K.M.3
Bedekovics, T.4
Bedwell, D.M.5
-
31
-
-
0032892950
-
Semisynthetic aminoglycoside antibiotics: Development and enzymatic modifications
-
Kondo S., Hotta K. Semisynthetic aminoglycoside antibiotics: Development and enzymatic modifications. J. Infect. Chemother. 1999, 5:1-9.
-
(1999)
J. Infect. Chemother.
, vol.5
, pp. 1-9
-
-
Kondo, S.1
Hotta, K.2
-
32
-
-
34948883252
-
Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites
-
Kondo J., Hainrichson M., Nudelman I., Shallom-Shezifi D., Barbieri C.M., Pilch D.S., Westhof E., Baasov T. Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites. Chembiochem 2007, 8:1700-1709.
-
(2007)
Chembiochem
, vol.8
, pp. 1700-1709
-
-
Kondo, J.1
Hainrichson, M.2
Nudelman, I.3
Shallom-Shezifi, D.4
Barbieri, C.M.5
Pilch, D.S.6
Westhof, E.7
Baasov, T.8
-
33
-
-
0015967386
-
Fidelity of protein synthesis with chicken embryo mitochondrial and cytoplasmic ribosomes
-
Kurtz D.I. Fidelity of protein synthesis with chicken embryo mitochondrial and cytoplasmic ribosomes. Biochemistry 1974, 13:572-577.
-
(1974)
Biochemistry
, vol.13
, pp. 572-577
-
-
Kurtz, D.I.1
-
34
-
-
33745829084
-
Recent developments in the synthesis of novel aminoglycoside antibiotics
-
Li J., Chang C.W. Recent developments in the synthesis of novel aminoglycoside antibiotics. Anti-infective Agents Med. Chem. 2006, 5:255-271.
-
(2006)
Anti-infective Agents Med. Chem.
, vol.5
, pp. 255-271
-
-
Li, J.1
Chang, C.W.2
-
35
-
-
33751325834
-
Biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics
-
Llewellyn N.M., Spencer J.B. Biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics. Nat. Prod. Rep. 2006, 23:864-874.
-
(2006)
Nat. Prod. Rep.
, vol.23
, pp. 864-874
-
-
Llewellyn, N.M.1
Spencer, J.B.2
-
36
-
-
49249130589
-
Chemoenzymatic acylation of aminoglycoside antibiotics
-
Llewellyn N.M., Spencer J.B. Chemoenzymatic acylation of aminoglycoside antibiotics. Chem. Commun. 2008, (32):3786-3788.
-
(2008)
Chem. Commun.
, Issue.32
, pp. 3786-3788
-
-
Llewellyn, N.M.1
Spencer, J.B.2
-
37
-
-
77953436025
-
Novel heterodimer antibiotics: A review of recent patent literature
-
Long D.D., Marquess D.G. Novel heterodimer antibiotics: A review of recent patent literature. Future Med. Chem. 2009, 1(6):1037-1050.
-
(2009)
Future Med. Chem.
, vol.1
, Issue.6
, pp. 1037-1050
-
-
Long, D.D.1
Marquess, D.G.2
-
38
-
-
14844348264
-
Molecular insights into aminoglycoside action and resistance
-
Magnet S., Blanchard J.S. Molecular insights into aminoglycoside action and resistance. Chem. Rev. 2005, 105:477-498.
-
(2005)
Chem. Rev.
, vol.105
, pp. 477-498
-
-
Magnet, S.1
Blanchard, J.S.2
-
39
-
-
0033929810
-
Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
-
Manuvakhova M., Keeling K., Bedwell D.M. Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system. RNA 2000, 6:1044-1055.
-
(2000)
RNA
, vol.6
, pp. 1044-1055
-
-
Manuvakhova, M.1
Keeling, K.2
Bedwell, D.M.3
-
40
-
-
33744503144
-
Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones
-
McKee E.E., Ferguson M., Bentley A.T., Marks T.A. Inhibition of mammalian mitochondrial protein synthesis by oxazolidinones. Antimicrob. Agents Chemother. 2006, 50:2042-2049.
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 2042-2049
-
-
McKee, E.E.1
Ferguson, M.2
Bentley, A.T.3
Marks, T.A.4
-
41
-
-
0023238983
-
Interaction of antibiotics with functional sites in 16S ribosomal RNA
-
Moazed D., Noller H.F. Interaction of antibiotics with functional sites in 16S ribosomal RNA. Nature 1987, 327:389-394.
-
(1987)
Nature
, vol.327
, pp. 389-394
-
-
Moazed, D.1
Noller, H.F.2
-
42
-
-
4744348954
-
Molecular aspects of renal handling of aminoglycosides and strategies for preventing the nephrotoxicity
-
Nagai J., Takano M. Molecular aspects of renal handling of aminoglycosides and strategies for preventing the nephrotoxicity. Drug Metab. Pharmacokinet. 2004, 19:159-170.
-
(2004)
Drug Metab. Pharmacokinet.
, vol.19
, pp. 159-170
-
-
Nagai, J.1
Takano, M.2
-
43
-
-
33750689865
-
Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations
-
Nudelman I., Rebibo-Sabbah A., Shallom-Shezifi D., Hainrichson M., Stahl I., Ben-Yosef T., Baasov T. Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. Bioorg. Med. Chem. Lett. 2006, 16:6310-6315.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 6310-6315
-
-
Nudelman, I.1
Rebibo-Sabbah, A.2
Shallom-Shezifi, D.3
Hainrichson, M.4
Stahl, I.5
Ben-Yosef, T.6
Baasov, T.7
-
44
-
-
53849129237
-
Combined chemical-enzymatic assembly of aminoglycoside derivatives with N-1-AHB side chain
-
Nudelman I., Chen L., Llewellyn N.M., Sahraoui E.H., Cherniavsky M., Spencer J.B., Baasov T. Combined chemical-enzymatic assembly of aminoglycoside derivatives with N-1-AHB side chain. Adv. Synth. Catal. 2008, 350:1682-1688.
-
(2008)
Adv. Synth. Catal.
, vol.350
, pp. 1682-1688
-
-
Nudelman, I.1
Chen, L.2
Llewellyn, N.M.3
Sahraoui, E.H.4
Cherniavsky, M.5
Spencer, J.B.6
Baasov, T.7
-
45
-
-
65649136885
-
Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations
-
Nudelman I., Rebibo-Sabbah A., Cherniavsky M., Belakhov V., Hainrichson M., Chen F., Schacht J., Pilch D.S., Ben-Yosef T., Baasov T. Development of novel aminoglycoside (NB54) with reduced toxicity and enhanced suppression of disease-causing premature stop mutations. J. Med. Chem. 2009, 52:2836-2845.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2836-2845
-
-
Nudelman, I.1
Rebibo-Sabbah, A.2
Cherniavsky, M.3
Belakhov, V.4
Hainrichson, M.5
Chen, F.6
Schacht, J.7
Pilch, D.S.8
Ben-Yosef, T.9
Baasov, T.10
-
46
-
-
77953133544
-
Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations
-
Nudelman I., Glikin D., Smolkin B., Hainrichson M., Belakhov V., Baasov T. Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations. Bioorg. Med. Chem. 2010, 18(11):3735-3746.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, Issue.11
, pp. 3735-3746
-
-
Nudelman, I.1
Glikin, D.2
Smolkin, B.3
Hainrichson, M.4
Belakhov, V.5
Baasov, T.6
-
47
-
-
20444469691
-
Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ
-
Numa M.M., Lee L.V., Hsu C.C., Bower K.E., Wong C.H. Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ. Chembiochem 2005, 6:1002-1006.
-
(2005)
Chembiochem
, vol.6
, pp. 1002-1006
-
-
Numa, M.M.1
Lee, L.V.2
Hsu, C.C.3
Bower, K.E.4
Wong, C.H.5
-
48
-
-
18844413446
-
Structural insights into translational fidelity
-
Ogle J.M., Ramakrishnan V. Structural insights into translational fidelity. Annu. Rev. Biochem. 2005, 74:129-177.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 129-177
-
-
Ogle, J.M.1
Ramakrishnan, V.2
-
49
-
-
75349102377
-
Chemical decay of an antibiotic inverts selection for resistance
-
Palmer A.C., Angelino E., Kishony R. Chemical decay of an antibiotic inverts selection for resistance. Nat. Chem. Biol. 2010, 6:105-107.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 105-107
-
-
Palmer, A.C.1
Angelino, E.2
Kishony, R.3
-
50
-
-
65249160092
-
Design, synthesis, and evaluation of novel fluoroquinolone-aminoglycoside hybrid antibiotics
-
Pokrovskaya V., Belakhov V., Hainrichson M., Yaron S., Baasov T. Design, synthesis, and evaluation of novel fluoroquinolone-aminoglycoside hybrid antibiotics. J. Med. Chem. 2009, 52:2243-2254.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2243-2254
-
-
Pokrovskaya, V.1
Belakhov, V.2
Hainrichson, M.3
Yaron, S.4
Baasov, T.5
-
51
-
-
35448977775
-
In vitro and ex vivo suppression by aminoglycosides of PCDH15 nonsense mutations underlying type 1 Usher syndrome
-
Rebibo-Sabbah A., Nudelman I., Ahmed Z.M., Baasov T., Ben-Yosef T. In vitro and ex vivo suppression by aminoglycosides of PCDH15 nonsense mutations underlying type 1 Usher syndrome. Hum. Genet. 2007, 122:373-381.
-
(2007)
Hum. Genet.
, vol.122
, pp. 373-381
-
-
Rebibo-Sabbah, A.1
Nudelman, I.2
Ahmed, Z.M.3
Baasov, T.4
Ben-Yosef, T.5
-
52
-
-
84964134387
-
Streptomycin, a substance exhibiting antibiotic activity against gram-positive and gram-negative bacteria
-
Schatz A., Bugie E., Waksman S.A. Streptomycin, a substance exhibiting antibiotic activity against gram-positive and gram-negative bacteria. Proc. Soc. Exp. Biol. Med. 1944, 55:66-69.
-
(1944)
Proc. Soc. Exp. Biol. Med.
, vol.55
, pp. 66-69
-
-
Schatz, A.1
Bugie, E.2
Waksman, S.A.3
-
53
-
-
33749354360
-
Structure of the 70S ribosome complexed with mRNA and tRNA
-
Selmer M., Dunham C.M., Murphy F.V., Weixlbaumer A., Petry S., Kelley A.C., Weir J.R., Ramakrishnan V. Structure of the 70S ribosome complexed with mRNA and tRNA. Science 2006, 313:1935-1942.
-
(2006)
Science
, vol.313
, pp. 1935-1942
-
-
Selmer, M.1
Dunham, C.M.2
Murphy, F.V.3
Weixlbaumer, A.4
Petry, S.5
Kelley, A.C.6
Weir, J.R.7
Ramakrishnan, V.8
-
54
-
-
0028875130
-
Synthesis of 5-deoxy-5-epifluoro derivatives of arbekacin, amikacin, and 1-N-[(S)-4-amino-2-hydroxybutanoyl]tobramycin (study on structure-toxicity relationships)
-
Shitara T., Umemura E., Tsuchiya T., Matsuno T. Synthesis of 5-deoxy-5-epifluoro derivatives of arbekacin, amikacin, and 1-N-[(S)-4-amino-2-hydroxybutanoyl]tobramycin (study on structure-toxicity relationships). Carbohydr. Res. 1995, 276:75-89.
-
(1995)
Carbohydr. Res.
, vol.276
, pp. 75-89
-
-
Shitara, T.1
Umemura, E.2
Tsuchiya, T.3
Matsuno, T.4
-
55
-
-
20344391159
-
Anthrax lethal factor inhibition
-
Shoop W.L., Xiong Y., Wiltsie J., Woods A., Guo J., Pivnichny J.V., Felcetto T., Michael B.F., Bansal A., Cummings R.T., Cunningham B.R., Friedlander A.M., et al. Anthrax lethal factor inhibition. Proc. Natl. Acad. Sci. USA 2005, 102:7958-7963.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7958-7963
-
-
Shoop, W.L.1
Xiong, Y.2
Wiltsie, J.3
Woods, A.4
Guo, J.5
Pivnichny, J.V.6
Felcetto, T.7
Michael, B.F.8
Bansal, A.9
Cummings, R.T.10
Cunningham, B.R.11
Friedlander, A.M.12
-
56
-
-
34247606403
-
New insights into aminoglycoside antibiotics and derivatives
-
Silva J.G., Carvalho I. New insights into aminoglycoside antibiotics and derivatives. Curr. Med. Chem. 2007, 14:1101-1119.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 1101-1119
-
-
Silva, J.G.1
Carvalho, I.2
-
58
-
-
76749100508
-
Adverse effects of aminoglycoside therapy
-
Wiley, Hoboken, New Jersey, D.P. Arya (Ed.)
-
Talaska A.E., Schacht J. Adverse effects of aminoglycoside therapy. Aminoglycoside antibiotics: from chemical biology to drug discovery 2007, 255-266. Wiley, Hoboken, New Jersey. D.P. Arya (Ed.).
-
(2007)
Aminoglycoside antibiotics: from chemical biology to drug discovery
, pp. 255-266
-
-
Talaska, A.E.1
Schacht, J.2
-
59
-
-
0004121735
-
-
Springer, New York, Heidelberg, H. Umezawa, I.R. Hooper (Eds.)
-
Aminoglycoside Antibiotics 1982, Springer, New York, Heidelberg. H. Umezawa, I.R. Hooper (Eds.).
-
(1982)
Aminoglycoside Antibiotics
-
-
-
60
-
-
0037770202
-
Versatility of aminoglycosides and prospects for their future
-
Vakulenko S.B., Mobashery S. Versatility of aminoglycosides and prospects for their future. Clin. Microbiol. Rev. 2003, 16:430-450.
-
(2003)
Clin. Microbiol. Rev.
, vol.16
, pp. 430-450
-
-
Vakulenko, S.B.1
Mobashery, S.2
-
61
-
-
0042337397
-
Molecular recognition of aminoglycoside antibiotics by ribosomal RNA and resistance enzymes: An analysis of x-ray crystal structures
-
Vicens Q., Westhof E. Molecular recognition of aminoglycoside antibiotics by ribosomal RNA and resistance enzymes: An analysis of x-ray crystal structures. Biopolymers 2003, 70:42-57.
-
(2003)
Biopolymers
, vol.70
, pp. 42-57
-
-
Vicens, Q.1
Westhof, E.2
-
62
-
-
84889359917
-
Design, chemical synthesis, and antibacterial activity of kanamycin and neomycin class aminoglycoside antibiotics
-
Wiley, Hoboken, New Jersey, D.P. Arya (Ed.)
-
Wang J., Chang C.W.T. Design, chemical synthesis, and antibacterial activity of kanamycin and neomycin class aminoglycoside antibiotics. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery 2007, 141-180. Wiley, Hoboken, New Jersey. 2nd edn. D.P. Arya (Ed.).
-
(2007)
Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery
, pp. 141-180
-
-
Wang, J.1
Chang, C.W.T.2
-
63
-
-
67649143315
-
Mechanisms of aminoglycoside antibiotic resistance
-
CRC press, Taylor & Francis group, Boca Raton, FL, K. Lewis, A.A. Salyers, H.W. Taber, R.G. Wax (Eds.)
-
Wright G.D. Mechanisms of aminoglycoside antibiotic resistance. Bacterial Resistance to Antimicrobials 2008, 71-101. CRC press, Taylor & Francis group, Boca Raton, FL. 2nd edn. K. Lewis, A.A. Salyers, H.W. Taber, R.G. Wax (Eds.).
-
(2008)
Bacterial Resistance to Antimicrobials
, pp. 71-101
-
-
Wright, G.D.1
-
64
-
-
65649124513
-
Drug interactions and the evolution of antibiotic resistance
-
Yeh P.J., Hegreness M.J., Aiden A.P., Kishony R. Drug interactions and the evolution of antibiotic resistance. Nat. Rev. 2009, 7:460-466.
-
(2009)
Nat. Rev.
, vol.7
, pp. 460-466
-
-
Yeh, P.J.1
Hegreness, M.J.2
Aiden, A.P.3
Kishony, R.4
-
66
-
-
34247593152
-
Modifications of aminoglycoside antibiotics targeting RNA
-
Zhou J., Wang G., Zhang L.H., Ye X.S. Modifications of aminoglycoside antibiotics targeting RNA. Med. Res. Rev. 2007, 27:279-316.
-
(2007)
Med. Res. Rev.
, vol.27
, pp. 279-316
-
-
Zhou, J.1
Wang, G.2
Zhang, L.H.3
Ye, X.S.4
-
67
-
-
33845996905
-
Aminoglycoside-induced translational read-through in disease: Overcoming nonsense mutations by pharmacogenetic therapy
-
Zingman L.V., Park S., Olson T.M., Alekseev A.E., Terzic A. Aminoglycoside-induced translational read-through in disease: Overcoming nonsense mutations by pharmacogenetic therapy. Clin. Pharmacol. Ther. 2007, 81:99-103.
-
(2007)
Clin. Pharmacol. Ther.
, vol.81
, pp. 99-103
-
-
Zingman, L.V.1
Park, S.2
Olson, T.M.3
Alekseev, A.E.4
Terzic, A.5
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