Enhanced RNA binding of dimerized aminoglycosides

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 7, 1999, Pages 1361-1371

  Michael, Katja ^a   Wang, Hai ^a   Tor, Yitzhak ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aminoglycoside antibiotics; Electrostatics; Inhibition; Ribozyme

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; FRAMYCETIN; KANAMYCIN A; TOBRAMYCIN;

ARTICLE; BINDING SITE; CHEMICAL MODIFICATION; DIMERIZATION; IONIC STRENGTH; KINETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RNA BINDING; TETRAHYMENA;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DIMERIZATION; DISULFIDES; KINETICS; NEOMYCIN; NUCLEIC ACID CONFORMATION; OSMOLAR CONCENTRATION; RNA; RNA, CATALYTIC; TETRAHYMENA; TOBRAMYCIN;

BACTERIA (MICROORGANISMS); TETRAHYMENA;

EID: 0033007592     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00071-1     Document Type: Article

References (36)

1. Davies J., Davis B. D., J. Biol. Chem. 1968, 243, 3312.
2. Moazed D., Noller H.F. Nature. 327:1987;389.
3. Zapp M.L., Stern S., Green M.R. Cell. 74:1993;969.
4. Mei H.-Y., Galan A.A., Halim N.S., Mack D.P., Moreland D.W., Sanders K.B., Truong H.N., Czarnik A.W. Bioorg. Med. Chem. Lett. 5:1995;2755.
5. Koeda, T.; Umemura, K.; Yokota, M. In Aminoglycoside Antibiotics. Umezawa, H., Hooper, R., Eds.; Springer-Verlag: Berlin, 1982; Vol. 62, pp 293-356.
6. von Ahsen U., Davies J., Schroeder R. Nature. 353:1991;368.
7. von Ahsen U., Davies J., Schroeder R. J. Mol. Biol. 226:1992;935.
8. Davies, J.; von Ahsen, U.; Schroeder, R. In The RNA World; Gesteland, R. F., Atkins, J. F., Eds.; Cold Spring Harbor Laboratory Press: New York, 1993. pp 185-204.
9. Stage T.K., Hertel K.J., Uhlenbeck O.C. RNA. 1:1995;95.
10. Wang H., Tor Y. J. Am. Chem. Soc. 119:1997;8734.
11. Rogers J., Chang A.H., von Ahsen U., Schroeder R., Davies J. J. Mol. Biol. 259:1996;916.
12. Chia J.-S., Wu H.-L., Wang H.-W., Chen D.-S., Chen P.-J. J. Biomed. Sci. 4:1997;208.
13. Michael K., Tor Y. Chem. Eur. J. 4:1998;2091.
14. Hendrix M., Alper P.B., Priestley E.S., Wong C.-H. Angew. Chem., Int. Ed. Engl. 36:1997;95.
15. Wong C.-H., Hendrix M., Manning D.D., Rosenbohm C., Greenberg W.A. J. Am. Chem. Soc. 120:1998;8319.
16. Wang H., Tor Y. Angew. Chem., Int. Ed. 37:1998;109.
17. Clouet-d'Orval B., Stage T.K., Uhlenbeck O.C. Biochemistry. 34:1995;11186.
18. Hermann T., Westhof E. J. Mol. Biol. 276:1998;903.
19. Tor Y., Hermann T., Westhof E. Chem. Biol. 5:1998;R277.
20. Wang H., Tor Y. Bioorg. Med. Chem. Lett. 7:1997;1951.
21. Hendrix M., Priestley E.S., Joyce G.F., Wong C.-H. J. Am. Chem. Soc. 119:1997;3641.
22. Kirk, S. R.; Tor, Y. Bioorg. Med. Chem. 1999, in press.
23. Cech T. Annu. Rev. Biochem. 59:1990;543.
24. Cate J.H., Hanna R.L., Doudna J.A. Nature Struct. Biol. 4:1997;553.
25. Michel F., Westhof E. J. Mol. Biol. 216:1990;585.
26. Zaug A.J., Grosshans C.A., Cech T.R. Biochemistry. 27:1988;8924.
27. Grosshans C.A., Cech T.R. Biochemistry. 28:1989;6888.
28. deHaseth P.L., Lohman T.M., Record M.T. Jr. J. Mol. Biol. 16:1977;4783.
29. Misra V.K., Sharp K.A., Friedman R.A., Honig B. J. Mol. Biol. 238:1994;245.
30. Dorman D.E., Paschal J.W., Merkel K.E. J. Am. Chem. Soc. 98:1976;6885.
31. Botto R.E., Coxon B. J. Am. Chem. Soc. 105:1983;1021.
32. Szilágyi L., Pusztahelyi Z.S., Jakab S., Kovács I. Carbohydr. Res. 247:1993;99.
33. Williams D.H., Westwell M.S. Chem. Soc. Rev. 27:1998;57.
34. Milligan J.F., Groebe D.R., Witherell G.W., Uhlenbeck O.C. Nucleic Acids Res. 15:1987;8783.
35. Sambrook, J.; Fritsch, E. F.; Maniatis, T. Molecular Cloning (2nd ed.); Cold Spring Harbor Laboratory Press: New York, 1989.
36. Herschlag D., Cech T.R. Biochemistry. 29:1990;10159.