-
2
-
-
78650622904
-
The sensors and regulators of cell-matrix surveillance in anoikis-resistance of tumors
-
Nagaprashantha LD, Vatsyayan R, Lelsani PC, Awasthi S, Singhal SS. The sensors and regulators of cell-matrix surveillance in anoikis-resistance of tumors. Int J Cancer. 2011;128:743-52.
-
(2011)
Int J Cancer
, vol.128
, pp. 743-752
-
-
Nagaprashantha, L.D.1
Vatsyayan, R.2
Lelsani, P.C.3
Awasthi, S.4
Singhal, S.S.5
-
4
-
-
0031569914
-
Cell adhesion in vascular biology. New insights into integrin-ligand interaction
-
Loftus JC, Liddington RC. Cell adhesion in vascular biology. New insights into integrin-ligand interaction. J Clin Invest. 1997;99:2302-6.
-
(1997)
J Clin Invest
, vol.99
, pp. 2302-2306
-
-
Loftus, J.C.1
Liddington, R.C.2
-
5
-
-
0028877919
-
Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for Src family kinases
-
Calalb MB, Polte TR, Hanks SK. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol Cell Biol. 1995;15:954-63.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 954-963
-
-
Calalb, M.B.1
Polte, T.R.2
Hanks, S.K.3
-
6
-
-
29044447052
-
Mechanisms of focal adhesion kinase regulation
-
Cohen LA, Guan JL. Mechanisms of focal adhesion kinase regulation. Curr Cancer Drug Targets. 2005;5:629-43.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 629-643
-
-
Cohen, L.A.1
Guan, J.L.2
-
7
-
-
0038482050
-
Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
-
Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem. 2003;278:18811-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 18811-18816
-
-
Ley, R.1
Balmanno, K.2
Hadfield, K.3
Weston, C.4
Cook, S.J.5
-
8
-
-
0034194714
-
Matrix survival signaling: From fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase
-
Almeida EA, Ilic D, Han Q, Hauck CR, Jin F, Kawakatsu H, et al. Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase. J Cell Biol. 2000;149:741-54.
-
(2000)
J Cell Biol
, vol.149
, pp. 741-754
-
-
Almeida, E.A.1
Ilic, D.2
Han, Q.3
Hauck, C.R.4
Jin, F.5
Kawakatsu, H.6
-
9
-
-
2342627918
-
Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells
-
Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery. 2004;135:555-62.
-
(2004)
Surgery
, vol.135
, pp. 555-562
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
10
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer. 2002;2:442-54.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
11
-
-
0025818032
-
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
-
Vleminckx K, Vakaet Jr L, Mareel M, Fiers W, van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell. 1991;66:107-19.
-
(1991)
Cell
, vol.66
, pp. 107-119
-
-
Vleminckx, K.1
Vakaet Jr., L.2
Mareel, M.3
Fiers, W.4
Van Roy, F.5
-
12
-
-
85047698213
-
Correlation of snail expression with histologicalgrade and lymph node status in breast carcinomas
-
Blanco MJ, Moreno-Bueno G, Sarrio D, Locascio A, Cano A, Palacios J, et al. Correlation of snail expression with histologicalgrade and lymph node status in breast carcinomas. Oncogene. 2002;21:3241-6.
-
(2002)
Oncogene
, vol.21
, pp. 3241-3246
-
-
Blanco, M.J.1
Moreno-Bueno, G.2
Sarrio, D.3
Locascio, A.4
Cano, A.5
Palacios, J.6
-
13
-
-
0346363757
-
Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
-
Peinado H, Ballestar E, Esteller M, Cano A. Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Mol Cell Biol. 2004;24:306-19.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 306-319
-
-
Peinado, H.1
Ballestar, E.2
Esteller, M.3
Cano, A.4
-
14
-
-
24644480749
-
Molecular requirements for epithelial-mesenchymal transition during tumor progression
-
Huber MA, Kraut N, Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol. 2005;17:548-58.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 548-558
-
-
Huber, M.A.1
Kraut, N.2
Beug, H.3
-
15
-
-
33244463813
-
Complex networks orchestrate epithelial-mesenchymal transitions
-
Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Rev Mol Cell Biol. 2006;7:131-42.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 131-142
-
-
Thiery, J.P.1
Sleeman, J.P.2
-
16
-
-
0034658674
-
Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition
-
ZondagGC, Evers EE, tenKlooster JP, Janssen L, van derKammen RA, Collard JG. Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition. J Cell Biol. 2000;149:775-82.
-
(2000)
J Cell Biol
, vol.149
, pp. 775-782
-
-
Zondag, G.C.1
Evers, E.E.2
TenKlooster, J.P.3
Janssen, L.4
Van DerKammen, R.A.5
Collard, J.G.6
-
17
-
-
35148832569
-
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
-
Lo HW, Tsu SC, Xia W, Cao X, Shih JY, Wei Y, et al. Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression. Cancer Res. 2007;67:9066-76.
-
(2007)
Cancer Res
, vol.67
, pp. 9066-9076
-
-
Lo, H.W.1
Tsu, S.C.2
Xia, W.3
Cao, X.4
Shih, J.Y.5
Wei, Y.6
-
18
-
-
67650045932
-
A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis
-
Smit MA, Geiger TR, Song JY, Gitelman I, Peeper DS. A Twist-Snail axis critical for TrkB-induced epithelial-mesenchymal transition-like transformation, anoikis resistance, and metastasis. Mol Cell Biol. 2009;29:3722-37.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3722-3737
-
-
Smit, M.A.1
Geiger, T.R.2
Song, J.Y.3
Gitelman, I.4
Peeper, D.S.5
-
19
-
-
67650999217
-
Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
-
Arumugam T, Ramachandran V, Fournier KF, Wang H, Marquis L, Abbruzzese JL, et al. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res. 2009;69:5820-8.
-
(2009)
Cancer Res
, vol.69
, pp. 5820-5828
-
-
Arumugam, T.1
Ramachandran, V.2
Fournier, K.F.3
Wang, H.4
Marquis, L.5
Abbruzzese, J.L.6
-
20
-
-
33750614651
-
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis
-
Derksen PW, Liu X, Saridin F, van der Gulden H, Zevenhoven J, Evers B, et al. Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. Cancer Cell. 2006;10:437-49.
-
(2006)
Cancer Cell
, vol.10
, pp. 437-449
-
-
Derksen, P.W.1
Liu, X.2
Saridin, F.3
Van Der Gulden, H.4
Zevenhoven, J.5
Evers, B.6
-
21
-
-
16844378813
-
Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells
-
Berezovskaya O, Schimmer AD, Glinskii AB, Pinilla C, Hoffman RM, Reed JC, et al. Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells. Cancer Res. 2005;65:2378-86.
-
(2005)
Cancer Res
, vol.65
, pp. 2378-2386
-
-
Berezovskaya, O.1
Schimmer, A.D.2
Glinskii, A.B.3
Pinilla, C.4
Hoffman, R.M.5
Reed, J.C.6
-
22
-
-
0842329842
-
CEA-CAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells
-
Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. CEA-CAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells. Oncogene. 2004;23:465-73.
-
(2004)
Oncogene
, vol.23
, pp. 465-473
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
-
23
-
-
18844415829
-
Co-morbidity leads to altered treatment and worse survival of elderly patients with colorectal cancer
-
Lemmens VE, Janssen-Heijnen ML, Verheij CD, Houterman S, Repelaer van Driel OJ, Coebergh JW. Co-morbidity leads to altered treatment and worse survival of elderly patients with colorectal cancer. Br J Surg. 2005;92:615-23.
-
(2005)
Br J Surg
, vol.92
, pp. 615-623
-
-
Lemmens, V.E.1
Janssen-Heijnen, M.L.2
Verheij, C.D.3
Houterman, S.4
Repelaer Van Driel, O.J.5
Coebergh, J.W.6
-
24
-
-
33845762340
-
Multi-target therapeutics: When the whole is greater than the sumof the parts
-
Zimmermann GR, Lehar J, Keith CT. Multi-target therapeutics: when the whole is greater than the sumof the parts. Drug Discovery Today. 2007;12:34-42.
-
(2007)
Drug Discovery Today
, vol.12
, pp. 34-42
-
-
Zimmermann, G.R.1
Lehar, J.2
Keith, C.T.3
-
25
-
-
0028670298
-
Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen
-
Montgomery AM, Reisfeld RA, Cheresh DA. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proc Nat Acad Sci. 1994;91:8856-60.
-
(1994)
Proc Nat Acad Sci
, vol.91
, pp. 8856-8860
-
-
Montgomery, A.M.1
Reisfeld, R.A.2
Cheresh, D.A.3
-
26
-
-
58549092250
-
Active N-Ras and B-Raf inhibit anoikis by down-regulating Bim expression in melanocytic cells
-
Goldstein NB, Johannes WU, Gadeliya AV, Green MR, Fujita M, Norris DA, et al. Active N-Ras and B-Raf inhibit anoikis by down-regulating Bim expression in melanocytic cells. J Invest Dermatol. 2009;129:432-7.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 432-437
-
-
Goldstein, N.B.1
Johannes, W.U.2
Gadeliya, A.V.3
Green, M.R.4
Fujita, M.5
Norris, D.A.6
-
27
-
-
31144453233
-
BRAF mutation predicts sensitivity to MEK inhibition
-
Solit DB, Garraway LA, Pratilas CA, Sawai A, Getz G, Basso A, et al. BRAF mutation predicts sensitivity to MEK inhibition. Nature. 2006;439:358-62.
-
(2006)
Nature
, vol.439
, pp. 358-362
-
-
Solit, D.B.1
Garraway, L.A.2
Pratilas, C.A.3
Sawai, A.4
Getz, G.5
Basso, A.6
-
28
-
-
79959692800
-
Anoikis induction andmetastasis suppression by a new integrin alphavbeta3 inhibitor in human melanoma cell line M21
-
Zhang Y, Yang M, Ji Q, Fan D, Peng H, Yang C, et al. Anoikis induction andmetastasis suppression by a new integrin alphavbeta3 inhibitor in human melanoma cell line M21. Invest New Drugs. 2011;29:666-73.
-
(2011)
Invest New Drugs
, vol.29
, pp. 666-673
-
-
Zhang, Y.1
Yang, M.2
Ji, Q.3
Fan, D.4
Peng, H.5
Yang, C.6
-
29
-
-
84862695999
-
FDA approval for vemurafenib & companion diagnostic test for late-stage melanoma
-
August
-
Stockwell S. FDA approval for vemurafenib & companion diagnostic test for late-stage melanoma. Oncology Times. August 2011.
-
(2011)
Oncology Times
-
-
Stockwell, S.1
-
30
-
-
65649108998
-
AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study
-
abs # 9033
-
Dummer R, Robert CP, Chapman PB, Sosman JA, Middleton M, Bastholt L, et al. AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: an open-label, randomized, multicenter, phase II study. J Clin Oncol. 2008; 26: abs # 9033).
-
(2008)
J Clin Oncol
, vol.26
-
-
Dummer, R.1
Robert, C.P.2
Chapman, P.B.3
Sosman, J.A.4
Middleton, M.5
Bastholt, L.6
-
31
-
-
77649137632
-
The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): A phase I open-label multicenter trial in patients with advanced cancer
-
Banerji U, Camidge DR, Verheul HM, Agarwal R, Sarker D, Kaye SB, et al. The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer. Clin Cancer Res. 2010;16:1613-23.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1613-1623
-
-
Banerji, U.1
Camidge, D.R.2
Verheul, H.M.3
Agarwal, R.4
Sarker, D.5
Kaye, S.B.6
-
32
-
-
77951003656
-
Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States
-
Grossman SA, YeX, Piantadosi S,Desideri S, NaborsLB, Rosenfeld M, et al. Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States. Clin Cancer Res. 2010;16:2443-9.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2443-2449
-
-
Grossman, S.A.1
Ye, X.2
Piantadosi, S.3
Desideri, S.4
Nabors, L.B.5
Rosenfeld, M.6
-
33
-
-
13444275480
-
Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion
-
Bellail AC, Hunter SB, Brat DJ, Tan C, Van Meir EG. Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. Int J Biochem Cell Biol. 2004;36:1046-69.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1046-1069
-
-
Bellail, A.C.1
Hunter, S.B.2
Brat, D.J.3
Tan, C.4
Van Meir, E.G.5
-
34
-
-
51449124031
-
Cilengitide: An integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme
-
Reardon DA, Nabors LB, Stupp R, Mikkelsen T. Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme. Expert Opin Invest Drugs. 2008;17:1225-35.
-
(2008)
Expert Opin Invest Drugs
, vol.17
, pp. 1225-1235
-
-
Reardon, D.A.1
Nabors, L.B.2
Stupp, R.3
Mikkelsen, T.4
-
35
-
-
74049162874
-
Small molecule integrin antagonists in cancer therapy
-
Paolillo M, Russo MA, Serra M, Colombo L, Schinelli S. Small molecule integrin antagonists in cancer therapy. Mini Rev Med Chem. 2009;9:1439-46.
-
(2009)
Mini Rev Med Chem
, vol.9
, pp. 1439-1446
-
-
Paolillo, M.1
Russo, M.A.2
Serra, M.3
Colombo, L.4
Schinelli, S.5
-
36
-
-
33750541962
-
Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype
-
Salmaggi A, Boiardi A, Gelati M, Russo A, Calatozzolo C, Ciusani E, et al. Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype. Glia. 2006;54:850-60.
-
(2006)
Glia
, vol.54
, pp. 850-860
-
-
Salmaggi, A.1
Boiardi, A.2
Gelati, M.3
Russo, A.4
Calatozzolo, C.5
Ciusani, E.6
-
37
-
-
56249095776
-
An alpha5beta1 integrin inhibitor attenuates glioma growth
-
Farber K, Synowitz M, Zahn G, Vossmeyer D, Stragies R, van Rooijen N, et al. An alpha5beta1 integrin inhibitor attenuates glioma growth. Mol Cell Neurosci. 2008;39:579-85.
-
(2008)
Mol Cell Neurosci
, vol.39
, pp. 579-585
-
-
Farber, K.1
Synowitz, M.2
Zahn, G.3
Vossmeyer, D.4
Stragies, R.5
Van Rooijen, N.6
-
38
-
-
0034601436
-
The integrin-linked kinase (ILK) suppresses anoikis
-
Attwell S, Roskelley C, Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene. 2000;19:3811-5.
-
(2000)
Oncogene
, vol.19
, pp. 3811-3815
-
-
Attwell, S.1
Roskelley, C.2
Dedhar, S.3
-
39
-
-
19944411156
-
Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth
-
Edwards LA, Thiessen B, Dragowska WH, Daynard T, Bally MB, Dedhar S. Inhibition of ILK in PTEN-mutant human glioblastomas inhibits PKB/Akt activation, induces apoptosis, and delays tumor growth. Oncogene. 2005;24:3596-605.
-
(2005)
Oncogene
, vol.24
, pp. 3596-3605
-
-
Edwards, L.A.1
Thiessen, B.2
Dragowska, W.H.3
Daynard, T.4
Bally, M.B.5
Dedhar, S.6
-
40
-
-
28044461715
-
Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma
-
Koul D, Shen R, Bergh S, Lu Y, de Groot JF, Liu TJ, et al. Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma. Mol Cancer Ther. 2005;4:1681-8.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1681-1688
-
-
Koul, D.1
Shen, R.2
Bergh, S.3
Lu, Y.4
De Groot, J.F.5
Liu, T.J.6
-
41
-
-
79958043675
-
-
Bethesda, MD, based on November 2010 SEER data submission, posted to the SEER web site
-
Howlader N, Noone AM, Krapcho M, Neyman N, Aminou R, Waldron W, et al. (eds). SEER Cancer Statistics Review, 1975-2008, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975-2008/, based on November 2010 SEER data submission, posted to the SEER web site, 2011.
-
(2011)
SEER Cancer Statistics Review, 1975-2008
-
-
Howlader, N.1
Noone, A.M.2
Krapcho, M.3
Neyman, N.4
Aminou, R.5
Waldron, W.6
-
42
-
-
57749111970
-
Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): A pilot study
-
Balan V, Nangia-Makker P, Schwartz AG, Jung YS, Tait L, Hogan V, et al. Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study. Cancer Res. 2008;68:10045-50.
-
(2008)
Cancer Res
, vol.68
, pp. 10045-10050
-
-
Balan, V.1
Nangia-Makker, P.2
Schwartz, A.G.3
Jung, Y.S.4
Tait, L.5
Hogan, V.6
-
43
-
-
0024402440
-
Identification of the metastasis-associated, galactoside-binding lectin as a chimeric gene product with homology to an IgE-binding protein
-
Raz A, Pazerini G, Carmi P. Identification of the metastasis-associated, galactoside-binding lectin as a chimeric gene product with homology to an IgE-binding protein. Cancer Res. 1989;49:3489-93.
-
(1989)
Cancer Res
, vol.49
, pp. 3489-3493
-
-
Raz, A.1
Pazerini, G.2
Carmi, P.3
-
44
-
-
0036118467
-
Role of galectin-3 in breast cancer metastasis: Involvement of nitric oxide
-
Song YK, Billiar TR, Lee YJ. Role of galectin-3 in breast cancer metastasis: involvement of nitric oxide. Am J Pathol. 2002;160:1069-75.
-
(2002)
Am J Pathol
, vol.160
, pp. 1069-1075
-
-
Song, Y.K.1
Billiar, T.R.2
Lee, Y.J.3
-
45
-
-
0030031430
-
Galectin-3, a beta-galactoside-binding animal lectin, is a marker of anaplastic large-cell lymphoma
-
Konstantinov KN, Robbins BA, Liu FT. Galectin-3, a beta-galactoside- binding animal lectin, is a marker of anaplastic large-cell lymphoma. Am J Pathol. 1996;148:25-30.
-
(1996)
Am J Pathol
, vol.148
, pp. 25-30
-
-
Konstantinov, K.N.1
Robbins, B.A.2
Liu, F.T.3
-
46
-
-
0030707480
-
Galectin-3: A novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
-
Akahani S, Nangia-Makker P, Inohara H, Kim HR, Raz A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res. 1997;57:5272-6.
-
(1997)
Cancer Res
, vol.57
, pp. 52726
-
-
Akahani, S.1
Nangia-Makker, P.2
Inohara, H.3
Kim, H.R.4
Raz, A.5
-
47
-
-
0033566695
-
Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells
-
Kim HR, Lin HM, Biliran H, Raz A. Cell cycle arrest and inhibition of anoikis by galectin-3 in human breast epithelial cells. Cancer Res. 1999;59:4148-54.
-
(1999)
Cancer Res
, vol.59
, pp. 4148-4154
-
-
Kim, H.R.1
Lin, H.M.2
Biliran, H.3
Raz, A.4
-
48
-
-
0037132694
-
Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin
-
Nangia-Makker P, Hogan V, Honjo Y, Baccarini S, Tait L, Bresalier R, et al. Inhibition of human cancer cell growth and metastasis in nude mice by oral intake of modified citrus pectin. J Nat Cancer Inst. 2002;94:1854-62.
-
(2002)
J Nat Cancer Inst
, vol.94
, pp. 1854-1862
-
-
Nangia-Makker, P.1
Hogan, V.2
Honjo, Y.3
Baccarini, S.4
Tait, L.5
Bresalier, R.6
-
49
-
-
33748076770
-
GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer
-
Lee E, Nichols P, Spicer D, Groshen S, Yu MC, Lee AS. GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer. Cancer Res. 2006;66:7849-53.
-
(2006)
Cancer Res
, vol.66
, pp. 7849-7853
-
-
Lee, E.1
Nichols, P.2
Spicer, D.3
Groshen, S.4
Yu, M.C.5
Lee, A.S.6
-
50
-
-
0035423875
-
The glucose-regulated proteins: Stress induction and clinical applications
-
Lee AS. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci. 2001;26:504-10.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 504-510
-
-
Lee, A.S.1
-
51
-
-
33646167400
-
ER stress, hypoxia tolerance and tumor progression
-
Koumenis C. ER stress, hypoxia tolerance and tumor progression. Curr Mol Med. 2006;6:55-69.
-
(2006)
Curr Mol Med
, vol.6
, pp. 55-69
-
-
Koumenis, C.1
-
52
-
-
0034021399
-
Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions
-
Fernandez PM, Tabbara SO, Jacobs LK, Manning FCR, Tsangaris TN, Shwartz AM, et al. Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions. Breast Cancer Res Treat. 2000;59:15-26.
-
(2000)
Breast Cancer Res Treat
, vol.59
, pp. 15-26
-
-
Fernandez, P.M.1
Tabbara, S.O.2
Jacobs, L.K.3
Manning, F.C.R.4
Tsangaris, T.N.5
Shwartz, A.M.6
-
53
-
-
33646171070
-
Stress induction of GRP78/BiP and its role in cancer
-
Li J, Lee AS. Stress induction of GRP78/BiP and its role in cancer. Curr Mol Med. 2006;6:45-54.
-
(2006)
Curr Mol Med
, vol.6
, pp. 45-54
-
-
Li, J.1
Lee, A.S.2
-
54
-
-
33751193479
-
Glucose regulated proteins in cancer progression, drug resistance and immunotherapy
-
Fu Y, Lee AS. Glucose regulated proteins in cancer progression, drug resistance and immunotherapy. Cancer Biol Ther. 2006;5:741-4.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 741-744
-
-
Fu, Y.1
Lee, A.S.2
-
55
-
-
21344437729
-
Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment
-
Dong D, Ko B, Baumeister P, Swenson S, Costa F, Markland F, et al. Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment. Cancer Res. 2005;65:5785-91.
-
(2005)
Cancer Res
, vol.65
, pp. 5785-5791
-
-
Dong, D.1
Ko, B.2
Baumeister, P.3
Swenson, S.4
Costa, F.5
Markland, F.6
-
56
-
-
37849035474
-
GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth
-
Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC. GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth. Mol Cell Biol. 2008;28:666-77.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 666-677
-
-
Shani, G.1
Fischer, W.H.2
Justice, N.J.3
Kelber, J.A.4
Vale, W.5
Gray, P.C.6
-
57
-
-
77956038678
-
(-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma
-
Luo T, Wang J, Yin Y, Hua H, Jing J, Sun X, et al. (-)-Epigallocatechin gallate sensitizes breast cancer cells to paclitaxel in a murine model of breast carcinoma. Breast Cancer Res. 2010;12:R8.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Luo, T.1
Wang, J.2
Yin, Y.3
Hua, H.4
Jing, J.5
Sun, X.6
-
58
-
-
0035885933
-
Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells
-
Hazlehurst LA, Valkov N, Wisner L, Storey JA, Boulware D, Sullivan DM, et al. Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells. Blood. 2001;98:1897-903.
-
(2001)
Blood
, vol.98
, pp. 1897-1903
-
-
Hazlehurst, L.A.1
Valkov, N.2
Wisner, L.3
Storey, J.A.4
Boulware, D.5
Sullivan, D.M.6
-
59
-
-
77951667670
-
Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation
-
Pongrakhananon V, Nimmannit U, Luanpitpong S, Rojanasakul Y, Chanvorachote P. Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation. Apoptosis. 2010;15:574-85.
-
(2010)
Apoptosis
, vol.15
, pp. 574-585
-
-
Pongrakhananon, V.1
Nimmannit, U.2
Luanpitpong, S.3
Rojanasakul, Y.4
Chanvorachote, P.5
-
60
-
-
9144231812
-
Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis
-
Chen HW, Yu SL, Chen JJ, Li HN, Lin YC, Yao PL, et al. Anti-invasive gene expression profile of curcumin in lung adenocarcinoma based on a high throughput microarray analysis. Mol Pharmacol. 2004;65:99-110.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 99-110
-
-
Chen, H.W.1
Yu, S.L.2
Chen, J.J.3
Li, H.N.4
Lin, Y.C.5
Yao, P.L.6
-
61
-
-
34447506459
-
Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, amajor metabolite of curcumin
-
Limtrakul P, ChearwaeW, Shukla S, Phisalphong C, Ambudkar SV. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, amajor metabolite of curcumin.Mol Cell Biochem. 2007;296:85-95.
-
(2007)
Mol Cell Biochem
, vol.296
, pp. 85-95
-
-
Limtrakul, P.1
Chearwae, W.2
Shukla, S.3
Phisalphong, C.4
Ambudkar, S.V.5
-
62
-
-
0034683576
-
A novel function for the tumor suppressor p16(INK4a): Induction of anoikis via upregulation of the alpha (5)beta(1) fibronectin receptor
-
Plath T, Detjen K, Welzel M, von Marschall Z, Murphy D, Schirner M, et al. A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha (5)beta(1) fibronectin receptor. J Cell Biol. 2000;150:1467-78.
-
(2000)
J Cell Biol
, vol.150
, pp. 1467-1478
-
-
Plath, T.1
Detjen, K.2
Welzel, M.3
Von Marschall, Z.4
Murphy, D.5
Schirner, M.6
-
63
-
-
0032487675
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature. 1998;396:84-8.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
64
-
-
0036554868
-
Trojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice
-
Hosotani R, Miyamoto Y, Fujimoto K, Doi R, Otaka A, Fujii N, et al. Trojan p16 peptide suppresses pancreatic cancer growth and prolongs survival in mice. Clin Cancer Res. 2002;8:1271-6.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1271-1276
-
-
Hosotani, R.1
Miyamoto, Y.2
Fujimoto, K.3
Doi, R.4
Otaka, A.5
Fujii, N.6
-
65
-
-
67650021249
-
Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1
-
Demers MJ, Thibodeau S, Noel D, Fujita N, Tsuruo T, Gauthier R, et al. Intestinal epithelial cancer cell anoikis resistance: EGFR-mediated sustained activation of Src overrides Fak-dependent signaling to MEK/Erk and/or PI3-K/Akt-1. J Cell Biochem. 2009;107:639-54.
-
(2009)
J Cell Biochem
, vol.107
, pp. 639-654
-
-
Demers, M.J.1
Thibodeau, S.2
Noel, D.3
Fujita, N.4
Tsuruo, T.5
Gauthier, R.6
-
66
-
-
4344627055
-
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB
-
Douma S, Van Laar T, Zevenhoven J, Meuwissen R, VanGarderen E, Peeper DS. Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature. 2004;430:1034-9.
-
(2004)
Nature
, vol.430
, pp. 1034-1039
-
-
Douma, S.1
Van Laar, T.2
Zevenhoven, J.3
Meuwissen, R.4
VanGarderen, E.5
Peeper, D.S.6
-
67
-
-
79957791306
-
Expression and significance of tyrosine kinase receptors B in nasopharyngeal carcinoma patients
-
Zhao W, Wen W, Zhang Z, Liao Z, Zhang S, Huang G. Expression and significance of tyrosine kinase receptors B in nasopharyngeal carcinoma patients. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2007;21:497-500.
-
(2007)
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
, vol.21
, pp. 497-500
-
-
Zhao, W.1
Wen, W.2
Zhang, Z.3
Liao, Z.4
Zhang, S.5
Huang, G.6
-
68
-
-
84862675593
-
K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr Virus (EBV)-associated nasopharyngeal carcinoma cells
-
in-press
-
Ng YK, Wong EY, Lau CP, Chan JP, Wong SC, Chan AS, et al. K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr Virus (EBV)-associated nasopharyngeal carcinoma cells. Invest New Drugs. 2010 (in-press).
-
(2010)
Invest New Drugs
-
-
Ng, Y.K.1
Wong, E.Y.2
Lau, C.P.3
Chan, J.P.4
Wong, S.C.5
Chan, A.S.6
-
69
-
-
77951723529
-
Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice
-
Cazorla M, Jouvenceau A, Rose C, Guilloux JP, Pilon C, Dranovsky A, et al. Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice. PLoS ONE. 2010;5:e9777.
-
(2010)
PLoS ONE
, vol.5
-
-
Cazorla, M.1
Jouvenceau, A.2
Rose, C.3
Guilloux, J.P.4
Pilon, C.5
Dranovsky, A.6
-
70
-
-
67651148122
-
Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway
-
Thress K, Macintyre T, Wang H, Whitston D, Liu ZY, Hoffmann E, et al. Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway. Mol Cancer Ther. 2009;8:1818-27.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1818-1827
-
-
Thress, K.1
Macintyre, T.2
Wang, H.3
Whitston, D.4
Liu, Z.Y.5
Hoffmann, E.6
-
71
-
-
33744925451
-
STAT3 as a downstream mediator of Trk signaling and functions
-
Ng YP, Cheung ZH, Ip NY. STAT3 as a downstream mediator of Trk signaling and functions. J Biol Chem. 2006;281:15636-44.
-
(2006)
J Biol Chem
, vol.281
, pp. 15636-15644
-
-
Ng, Y.P.1
Cheung, Z.H.2
Ip, N.Y.3
-
72
-
-
12944272024
-
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
-
Grandis JR, Drenning SD, Zeng Q, Watkins SC, Melhem MF, Endo S, et al. Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc Natl Acad Sci U S A. 2000;97:4227-32.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 4227-4232
-
-
Grandis, J.R.1
Drenning, S.D.2
Zeng, Q.3
Watkins, S.C.4
Melhem, M.F.5
Endo, S.6
-
73
-
-
0041620205
-
Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis
-
Hsiao JR, Jin YT, Tsai ST, Shiau AL, Wu CL, Su WC. Constitutive activation of STAT3 and STAT5 is present in the majority of nasopharyngeal carcinoma and correlates with better prognosis. Br J Cancer. 2003;89:344-9.
-
(2003)
Br J Cancer
, vol.89
, pp. 344-349
-
-
Hsiao, J.R.1
Jin, Y.T.2
Tsai, S.T.3
Shiau, A.L.4
Wu, C.L.5
Su, W.C.6
-
74
-
-
66449127943
-
Cross talk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt/ERK signaling
-
Neiva KG, Zhang Z, Miyazawa M, Warner KA, Karl E, Nor JE. Cross talk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt/ERK signaling. Neoplasia. 2009;11:583-93.
-
(2009)
Neoplasia
, vol.11
, pp. 583-593
-
-
Neiva, K.G.1
Zhang, Z.2
Miyazawa, M.3
Warner, K.A.4
Karl, E.5
Nor, J.E.6
-
75
-
-
73949160835
-
Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells
-
Lui VW, Yau DM, Wong EY, Ng YK, Lau CP, Ho Y, et al. Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells. Carcinogenesis. 2009;30:2085-94.
-
(2009)
Carcinogenesis
, vol.30
, pp. 2085-2094
-
-
Lui, V.W.1
Yau, D.M.2
Wong, E.Y.3
Ng, Y.K.4
Lau, C.P.5
Ho, Y.6
-
76
-
-
0041592695
-
Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer
-
Swan EA, Jasser SA, Holsinger FC, Doan D, Bucana C, Myers JN. Acquisition of anoikis resistance is a critical step in the progression of oral tongue cancer. Oral Oncol. 2003;39:648-55.
-
(2003)
Oral Oncol
, vol.39
, pp. 648-655
-
-
Swan, E.A.1
Jasser, S.A.2
Holsinger, F.C.3
Doan, D.4
Bucana, C.5
Myers, J.N.6
-
77
-
-
33748653109
-
Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas
-
Chung CH, Ely K, McGavran L, Varella-Garcia M, Parker J, Parker N, et al. Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas. J Clin Oncol. 2006;24:4170-6.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4170-4176
-
-
Chung, C.H.1
Ely, K.2
McGavran, L.3
Varella-Garcia, M.4
Parker, J.5
Parker, N.6
-
78
-
-
33749035470
-
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting
-
Sok JC, Coppelli FM, Thomas SM, LangoMN,Xi S, Hunt JL, et al. Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clin Cancer Res. 2006;12:5064-73.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5064-5073
-
-
Sok, J.C.1
Coppelli, F.M.2
Thomas, S.M.3
Lango, M.N.4
Xi, S.5
Hunt, J.L.6
-
79
-
-
34250711876
-
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma
-
Frederick BA, Helfrich BA, Coldren CD, Zheng D, Chan D, Bunn PA, et al. Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma. Mol Cancer Ther. 2007;6:1683-91.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1683-1691
-
-
Frederick, B.A.1
Helfrich, B.A.2
Coldren, C.D.3
Zheng, D.4
Chan, D.5
Bunn, P.A.6
-
80
-
-
0037067672
-
Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa B
-
Zeng Q, Chen S, You Z, Yang F, Carey TE, Saims D, et al. Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa B. J Biol Chem. 2002;277:25203-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 25203-25208
-
-
Zeng, Q.1
Chen, S.2
You, Z.3
Yang, F.4
Carey, T.E.5
Saims, D.6
-
81
-
-
0032054511
-
Over-expression of c-Src in areas of hyper-proliferation in head and neck cancer, premalignant lesions and benign mucosal disorders
-
van Oijen MG, Rijksen G, ten Broek FW, Slootweg PJ. Over-expression of c-Src in areas of hyper-proliferation in head and neck cancer, premalignant lesions and benign mucosal disorders. J Oral Pathol Med. 1998;27:147-52.
-
(1998)
J Oral Pathol Med
, vol.27
, pp. 147-152
-
-
Van Oijen, M.G.1
Rijksen, G.2
Ten Broek, F.W.3
Slootweg, P.J.4
-
82
-
-
79551709762
-
Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer
-
Sen B, Peng S, Saigal B, Williams MD, Johnson FM. Distinct interactions between c-Src and c-Met in mediating resistance to c-Src inhibition in head and neck cancer. Clin Cancer Res. 2011;17:514-24.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 514-524
-
-
Sen, B.1
Peng, S.2
Saigal, B.3
Williams, M.D.4
Johnson, F.M.5
-
83
-
-
79955487784
-
Phase 2 study of dasatinib in the treatment of head and neck squamous cell carcinoma
-
Brooks HD, Glisson BS, Bekele BN, Ginsberg LE, El-Naggar A, Culotta KS, et al. Phase 2 study of dasatinib in the treatment of head and neck squamous cell carcinoma. Cancer. 2011;117:2112-9.
-
(2011)
Cancer
, vol.117
, pp. 2112-2119
-
-
Brooks, H.D.1
Glisson, B.S.2
Bekele, B.N.3
Ginsberg, L.E.4
El-Naggar, A.5
Culotta, K.S.6
-
84
-
-
79960300164
-
Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells
-
Xu H, Stabile LP, Gubish CT, Gooding WE, Grandis JR, Siegfried JM. Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells. Clin Cancer Res. 2011;17:4425-38.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4425-4438
-
-
Xu, H.1
Stabile, L.P.2
Gubish, C.T.3
Gooding, W.E.4
Grandis, J.R.5
Siegfried, J.M.6
-
85
-
-
0346037266
-
Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2. Implication in head and neck squamous cell carcinoma progression
-
Zeng Q, McCauley LK, Wang CY. Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2. Implication in head and neck squamous cell carcinoma progression. J Biol Chem. 2002;277:50137-42.
-
(2002)
J Biol Chem
, vol.277
, pp. 50137-50142
-
-
Zeng, Q.1
McCauley, L.K.2
Wang, C.Y.3
-
86
-
-
62349138124
-
The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumor microenvironment
-
Greenhough A, Smartt HJ, Moore AE, Roberts HR, Williams AC, Paraskeva C, et al. The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumor microenvironment. Carcinogenesis. 2009;30:377-86.
-
(2009)
Carcinogenesis
, vol.30
, pp. 377-386
-
-
Greenhough, A.1
Smartt, H.J.2
Moore, A.E.3
Roberts, H.R.4
Williams, A.C.5
Paraskeva, C.6
-
87
-
-
79959958162
-
Phase 1 trial of concurrent erlotinib, celecoxib, and reirradiation for recurrent head and neck cancer
-
Kao J, Genden EM, Chen CT, Rivera M, Tong CC, Misiukiewicz K, et al. Phase 1 trial of concurrent erlotinib, celecoxib, and reirradiation for recurrent head and neck cancer. Cancer. 2011;117:3173-81.
-
(2011)
Cancer
, vol.117
, pp. 3173-3181
-
-
Kao, J.1
Genden, E.M.2
Chen, C.T.3
Rivera, M.4
Tong, C.C.5
Misiukiewicz, K.6
-
88
-
-
77955098807
-
Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis
-
Kumar P, Yadav A, Patel SN, Islam M, Pan Q, Merajver SD, et al. Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis. Mol Cancer. 2010;9:206.
-
(2010)
Mol Cancer
, vol.9
, pp. 206
-
-
Kumar, P.1
Yadav, A.2
Patel, S.N.3
Islam, M.4
Pan, Q.5
Merajver, S.D.6
-
89
-
-
23844491524
-
Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations
-
Mukohara T, Engelman JA, Hanna NH, Yeap BY, Kobayashi S, Lindeman N, et al. Differential effects of gefitinib and cetuximab on non-small-cell lung cancers bearing epidermal growth factor receptor mutations. J Natl Cancer Inst. 2005;97:1185-94.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1185-1194
-
-
Mukohara, T.1
Engelman, J.A.2
Hanna, N.H.3
Yeap, B.Y.4
Kobayashi, S.5
Lindeman, N.6
-
90
-
-
22044453790
-
Erlotinib in lung cancer-molecular and clinical predictors of outcome
-
Tsao MS, Sakurada A, Cutz JC, Zhu CQ, Kamel-Reid S, Squire J, et al. Erlotinib in lung cancer-molecular and clinical predictors of outcome. N Engl J Med. 2005;353:133-44.
-
(2005)
N Engl J Med
, vol.353
, pp. 133-144
-
-
Tsao, M.S.1
Sakurada, A.2
Cutz, J.C.3
Zhu, C.Q.4
Kamel-Reid, S.5
Squire, J.6
-
91
-
-
0036402066
-
The relationship between PTEN expression and anoikis in human lung carcinoma cell lines
-
Shanghai
-
Lei QY, Wang LY, Dai ZY, Zha XL. The relationship between PTEN expression and anoikis in human lung carcinoma cell lines. Sheng Wu HuaXue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2002;34:463-8.
-
(2002)
Sheng Wu HuaXue Yu Sheng Wu Wu Li Xue Bao
, vol.34
, pp. 463-468
-
-
Lei, Q.Y.1
Wang, L.Y.2
Dai, Z.Y.3
Zha, X.L.4
-
92
-
-
79952382550
-
Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer
-
Bao B, Ali S, Kong D, Sarkar SH, Wang Z, Banerjee S, et al. Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer. PLoS ONE. 2011;6:e17850.
-
(2011)
PLoS ONE
, vol.6
-
-
Bao, B.1
Ali, S.2
Kong, D.3
Sarkar, S.H.4
Wang, Z.5
Banerjee, S.6
-
93
-
-
33144483998
-
PPAR-gamma agonist increase gefitinib's antitumor activity through PTEN expression
-
Lee SY, Hur GY, Jung KH, Jung HC, Lee SY, Kim JH, et al. PPAR-gamma agonist increase gefitinib's antitumor activity through PTEN expression. Lung Cancer. 2006;51:297-301.
-
(2006)
Lung Cancer
, vol.51
, pp. 297-301
-
-
Lee, S.Y.1
Hur, G.Y.2
Jung, K.H.3
Jung, H.C.4
Lee, S.Y.5
Kim, J.H.6
-
94
-
-
57049132745
-
Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy
-
Thomson S, Petti F, Sujka-Kwok I, Epstein D, Haley JD. Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy. Clin Exp Metastasis. 2008;25:843-54.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 843-854
-
-
Thomson, S.1
Petti, F.2
Sujka-Kwok, I.3
Epstein, D.4
Haley, J.D.5
-
95
-
-
10944223361
-
Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis
-
Wei L, Yang Y, Zhang X, Yu Q. Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis. Oncogene. 2004;23:9052-61.
-
(2004)
Oncogene
, vol.23
, pp. 9052-9061
-
-
Wei, L.1
Yang, Y.2
Zhang, X.3
Yu, Q.4
-
96
-
-
77955503066
-
Phase II proof-of-concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer
-
Altorki N, Lane ME, Bauer T, Lee PC, Guarino MJ, Pass H, et al. Phase II proof-of-concept study of pazopanib monotherapy in treatment-naive patients with stage I/II resectable non-small-cell lung cancer. J Clin Oncol. 2010;28:3131-7.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3131-3137
-
-
Altorki, N.1
Lane, M.E.2
Bauer, T.3
Lee, P.C.4
Guarino, M.J.5
Pass, H.6
-
97
-
-
58149136153
-
Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy
-
Wang X, Hawk N, Yue P, Kauh J, Ramalingam SS, Fu H, et al. Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy. Cancer Biol Ther. 2008;7:1952-8.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1952-1958
-
-
Wang, X.1
Hawk, N.2
Yue, P.3
Kauh, J.4
Ramalingam, S.S.5
Fu, H.6
-
98
-
-
57349194139
-
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
-
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, et al. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med. 2008;14:1351-6.
-
(2008)
Nat Med
, vol.14
, pp. 1351-1356
-
-
Engelman, J.A.1
Chen, L.2
Tan, X.3
Crosby, K.4
Guimaraes, A.R.5
Upadhyay, R.6
-
99
-
-
77951658161
-
KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: Implication for combinatorial approach
-
Yoon YK, Kim HP, Han SW, Oh do Y, Im SA, Bang YJ, et al. KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach. Mol Carcinog. 2010;49:353-62.
-
(2010)
Mol Carcinog
, vol.49
, pp. 353-362
-
-
Yoon, Y.K.1
Kim, H.P.2
Han, S.W.3
Oh Do, Y.4
Im, S.A.5
Bang, Y.J.6
-
100
-
-
36549089617
-
SCH66336, inhibitor of protein farnesylation, blocks signal transducer and activators of transcription 3 signaling in lung cancer and interacts with a small molecule inhibitor of epidermal growth factor receptor/human epidermal growth factor receptor 2
-
Dowlati A, Kluge A, Nethery D, Halmos B, Kern JA. SCH66336, inhibitor of protein farnesylation, blocks signal transducer and activators of transcription 3 signaling in lung cancer and interacts with a small molecule inhibitor of epidermal growth factor receptor/human epidermal growth factor receptor 2. Anticancer Drugs. 2008;19:9-16.
-
(2008)
Anticancer Drugs
, vol.19
, pp. 9-16
-
-
Dowlati, A.1
Kluge, A.2
Nethery, D.3
Halmos, B.4
Kern, J.A.5
-
101
-
-
34548576919
-
Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides
-
Weerasinghe P, Garcia GE, Zhu Q, Yuan P, Feng L, Mao L, et al. Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides. Int J Oncol. 2007;31:129-36.
-
(2007)
Int J Oncol
, vol.31
, pp. 129-136
-
-
Weerasinghe, P.1
Garcia, G.E.2
Zhu, Q.3
Yuan, P.4
Feng, L.5
Mao, L.6
-
102
-
-
45749148684
-
Alpha(v)beta(3) Integrin-mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione-dependent elimination of drug-induced reactive oxidative species
-
Brozovic A, Majhen D, Roje V, Mikac N, Jakopec S, Fritz G, et al. Alpha(v)beta(3) Integrin-mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione-dependent elimination of drug-induced reactive oxidative species. Mol Pharmacol. 2008;74:298-306.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 298-306
-
-
Brozovic, A.1
Majhen, D.2
Roje, V.3
Mikac, N.4
Jakopec, S.5
Fritz, G.6
-
103
-
-
0042353628
-
RAL GTPases are linchpin modulators of human tumor-cell proliferation and survival
-
Chien Y, White MA. RAL GTPases are linchpin modulators of human tumor-cell proliferation and survival. EMBO Reports. 2003;4:800-6.
-
(2003)
EMBO Reports
, vol.4
, pp. 800-806
-
-
Chien, Y.1
White, M.A.2
-
104
-
-
60749110200
-
Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates
-
Singhal SS, Sehrawat A, Mehta A, Sahu M, Awasthi S. Functional reconstitution of RLIP76 catalyzing ATP-dependent transport of glutathione-conjugates. Int J Oncol. 2009;34:191-9.
-
(2009)
Int J Oncol
, vol.34
, pp. 191-199
-
-
Singhal, S.S.1
Sehrawat, A.2
Mehta, A.3
Sahu, M.4
Awasthi, S.5
-
105
-
-
78751529721
-
Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis
-
Singhal SS, Wickramarachchi D, Yadav S, Singhal J, Leake K, Vatsyayan R, et al. Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis. Mol Cancer Ther. 2011;10:16-28.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 16-28
-
-
Singhal, S.S.1
Wickramarachchi, D.2
Yadav, S.3
Singhal, J.4
Leake, K.5
Vatsyayan, R.6
-
106
-
-
74949118910
-
RLIP76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer
-
Singhal SS, Sehrawat A, Sahu M, Singhal P, Vatsyayan R, Lelsani P, et al. RLIP76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer. Int J Cancer. 126:1327-38.
-
Int J Cancer
, vol.126
, pp. 1327-1338
-
-
Singhal, S.S.1
Sehrawat, A.2
Sahu, M.3
Singhal, P.4
Vatsyayan, R.5
Lelsani, P.6
-
107
-
-
78649852581
-
RalBP1 is necessary for metastasis of human cancer cell lines
-
Wu Z, Owens C, ChandraN, PopovicK, ConawayM, Theodorescu D. RalBP1 is necessary for metastasis of human cancer cell lines. Neoplasia. 2010;12:1003-12.
-
(2010)
Neoplasia
, vol.12
, pp. 1003-1012
-
-
Wu, Z.1
Owens, C.2
Chandra, N.3
Popovic, K.4
Conaway, M.5
Theodorescu, D.6
-
108
-
-
80052725500
-
RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome
-
Singhal J, Nagaprashantha LD, Vatsyayan R, Awasthi S, Singhal SS. RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome. PLoS ONE. 2011;6(9):e24688.
-
(2011)
PLoS ONE
, vol.6
, Issue.9
-
-
Singhal, J.1
Nagaprashantha, L.D.2
Vatsyayan, R.3
Awasthi, S.4
Singhal, S.S.5
-
109
-
-
79952265105
-
Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice
-
Anisimov VN, Piskunova TS, Popovich IG, Zabezhinski MA, Tyndyk ML, Egormin PA, et al. Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice. Aging. 2010;2:945-58.
-
(2010)
Aging
, vol.2
, pp. 945-958
-
-
Anisimov, V.N.1
Piskunova, T.S.2
Popovich, I.G.3
Zabezhinski, M.A.4
Tyndyk, M.L.5
Egormin, P.A.6
-
110
-
-
37149010874
-
Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation
-
Campos AC, Molognoni F, Melo FH, Galdieri LC, Carneiro CR, D'Almeida V, et al. Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation. Neoplasia. 2007;9:1111-21.
-
(2007)
Neoplasia
, vol.9
, pp. 1111-1121
-
-
Campos, A.C.1
Molognoni, F.2
Melo, F.H.3
Galdieri, L.C.4
Carneiro, C.R.5
D'Almeida, V.6
-
111
-
-
67650482968
-
Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models
-
Festuccia C, Gravina GL, D'Alessandro AM, Muzi P, Millimaggi D, Dolo V, et al. Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models. Endocr Relat Cancer. 2009;16:401-13.
-
(2009)
Endocr Relat Cancer
, vol.16
, pp. 401-413
-
-
Festuccia, C.1
Gravina, G.L.2
D'Alessandro, A.M.3
Muzi, P.4
Millimaggi, D.5
Dolo, V.6
-
112
-
-
0345275879
-
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyl-transferase and reactivates methylation-silenced genes in cancer cell lines
-
Fang MZ, Wang Y, Ai N, Hou Z, Sun Y, Lu H, et al. Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyl-transferase and reactivates methylation-silenced genes in cancer cell lines. Cancer Res. 2003;63:7563-70.
-
(2003)
Cancer Res
, vol.63
, pp. 7563-7570
-
-
Fang, M.Z.1
Wang, Y.2
Ai, N.3
Hou, Z.4
Sun, Y.5
Lu, H.6
-
113
-
-
0036098932
-
Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells
-
Muscella A, Greco S, Elia MG, Storelli C, Marsigliante S. Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells. J Endocrinol. 2002;173:315-23.
-
(2002)
J Endocrinol
, vol.173
, pp. 315-323
-
-
Muscella, A.1
Greco, S.2
Elia, M.G.3
Storelli, C.4
Marsigliante, S.5
-
114
-
-
0032866353
-
Reduced expression of beta-subunit of Na, K-ATPase in human clear-cell renal cell carcinoma
-
Rajasekaran SA, Ball WJ, Bander NH, Liu H, Pardee JD, Rajasekaran AK. Reduced expression of beta-subunit of Na, K-ATPase in human clear-cell renal cell carcinoma. J Urol. 1999;162:574-80.
-
(1999)
J Urol
, vol.162
, pp. 574-580
-
-
Rajasekaran, S.A.1
Ball, W.J.2
Bander, N.H.3
Liu, H.4
Pardee, J.D.5
Rajasekaran, A.K.6
-
115
-
-
34249825771
-
The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers
-
Mijatovic T, Roland I, Van Quaquebeke E, Nilsson B, Mathieu A, Van Vynckt F, et al. The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers. J Pathol. 2007;212:170-9.
-
(2007)
J Pathol
, vol.212
, pp. 170-179
-
-
Mijatovic, T.1
Roland, I.2
Van Quaquebeke, E.3
Nilsson, B.4
Mathieu, A.5
Van Vynckt, F.6
-
116
-
-
10444275509
-
Recent insights into the structure and mechanism of the sodium pump
-
Horisberger JD. Recent insights into the structure and mechanism of the sodium pump. Physiology. 2004;19:377-87.
-
(2004)
Physiology
, vol.19
, pp. 377-387
-
-
Horisberger, J.D.1
-
117
-
-
66149142810
-
Inhibition of the sodium potassium adenosinetriphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation
-
Simpson CD, Mawji IA, Anyiwe K, Williams MA, Wang X, Venugopal AL, et al. Inhibition of the sodium potassium adenosinetriphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation. Cancer Res. 2009;69:2739-47.
-
(2009)
Cancer Res
, vol.69
, pp. 2739-2747
-
-
Simpson, C.D.1
Mawji, I.A.2
Anyiwe, K.3
Williams, M.A.4
Wang, X.5
Venugopal, A.L.6
-
118
-
-
26944491533
-
Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells
-
Yan SR, Joseph RR, Rosen K, Reginato MJ, Jackson A, Allaire N, et al. Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells. Oncogene. 2005;24:6482-91.
-
(2005)
Oncogene
, vol.24
, pp. 6482-6491
-
-
Yan, S.R.1
Joseph, R.R.2
Rosen, K.3
Reginato, M.J.4
Jackson, A.5
Allaire, N.6
-
119
-
-
33644974357
-
The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells
-
Mijatovic T, Op De Beeck A, Van Quaquebeke E, Dewelle J, Darro F, de Launoit Y, et al. The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells. Mol Cancer Ther. 2006;5:391-9.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 391-399
-
-
Mijatovic, T.1
Op De Beeck, A.2
Van Quaquebeke, E.3
Dewelle, J.4
Darro, F.5
De Launoit, Y.6
-
120
-
-
0033551665
-
Beta(1) integrin binds the 16-kDa subunit of vacuolar H(+)-ATPase at a site important for human papillomavirus E5 and platelet-derived growth factor signaling
-
Skinner MA, Wildeman AG. beta(1) integrin binds the 16-kDa subunit of vacuolar H(+)-ATPase at a site important for human papillomavirus E5 and platelet-derived growth factor signaling. J Biol Chem. 1999;274:23119-27.
-
(1999)
J Biol Chem
, vol.274
, pp. 23119-23127
-
-
Skinner, M.A.1
Wildeman, A.G.2
-
121
-
-
69149104880
-
Biological effects of a new vacuolar-H,-ATPase inhibitor in colon carcinoma cell lines
-
Supino R, Scovassi AI, Croce AC, Dal Bo L, Favini E, Corbelli A, et al. Biological effects of a new vacuolar-H,-ATPase inhibitor in colon carcinoma cell lines. Ann N Y Acad Sci. 2009;1171:606-16.
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 606-616
-
-
Supino, R.1
Scovassi, A.I.2
Croce, A.C.3
Dal Bo, L.4
Favini, E.5
Corbelli, A.6
-
122
-
-
34249685010
-
Mevalonate pathway: A review of clinical and therapeutical implications
-
Buhaescu I, Izzedine H. Mevalonate pathway: a review of clinical and therapeutical implications. Clin Biochem. 2007;40:575-84.
-
(2007)
Clin Biochem
, vol.40
, pp. 575-584
-
-
Buhaescu, I.1
Izzedine, H.2
-
123
-
-
0037664952
-
Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells
-
Oades GM, Senaratne SG, Clarke IA, Kirby RS, Colston KW. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells. J Urol. 2003;170:246-52.
-
(2003)
J Urol
, vol.170
, pp. 246-252
-
-
Oades, G.M.1
Senaratne, S.G.2
Clarke, I.A.3
Kirby, R.S.4
Colston, K.W.5
-
124
-
-
0141817178
-
Zoledronate (ZOL): Phase I and pharmacokinetics (PK)/pharmacodynamics (PD) study in cancer patients
-
Saeki T, Sasaki Y, Itoh T. Zoledronate (ZOL): phase I and pharmacokinetics (PK)/pharmacodynamics (PD) study in cancer patients. Bone. 2000;26:41S.
-
(2000)
Bone
, vol.26
-
-
Saeki, T.1
Sasaki, Y.2
Itoh, T.3
-
125
-
-
33745040807
-
Anticancer effects of zoledronic acid against human osteosarcoma cells
-
Kubista B, Trieb K, Sevelda F, Toma C, Arrich F, Heffeter P, et al. Anticancer effects of zoledronic acid against human osteosarcoma cells. J Orthop Res. 2006;24:1145-52.
-
(2006)
J Orthop Res
, vol.24
, pp. 1145-1152
-
-
Kubista, B.1
Trieb, K.2
Sevelda, F.3
Toma, C.4
Arrich, F.5
Heffeter, P.6
-
126
-
-
66749095489
-
Personalized cancer diagnostics and therapeutics
-
Roukos DH. Personalized cancer diagnostics and therapeutics. Expert Rev Mol Diagn. 2009;9:227-9.
-
(2009)
Expert Rev Mol Diagn
, vol.9
, pp. 227-229
-
-
Roukos, D.H.1
-
127
-
-
48449098623
-
Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs
-
Gascoigne KE, Taylor SS. Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs. Cancer Cell. 2008;14:111-22.
-
(2008)
Cancer Cell
, vol.14
, pp. 111-122
-
-
Gascoigne, K.E.1
Taylor, S.S.2
-
128
-
-
78650373804
-
Network medicine: A network-based approach to human disease
-
Barabasi AL, Gulbahce N, Loscalzo J. Network medicine: a network-based approach to human disease. Nat Rev Genet. 2011;12:56-68.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 56-68
-
-
Barabasi, A.L.1
Gulbahce, N.2
Loscalzo, J.3
-
129
-
-
0034036053
-
Incidence of sentinel node metastasis in patients with thin primary melanoma (≤ or 0 1 mm) with vertical growth phase
-
Bedrosian I, Faries MB, Guerry 4th D, Elenitsas R, Schuchter L, Mick R, et al. Incidence of sentinel node metastasis in patients with thin primary melanoma (≤ or 0 1 mm) with vertical growth phase. Ann Surg Oncol. 2000;7:262-7.
-
(2000)
Ann Surg Oncol
, vol.7
, pp. 262-267
-
-
Bedrosian, I.1
Faries, M.B.2
Guerry IV, D.3
Elenitsas, R.4
Schuchter, L.5
Mick, R.6
-
130
-
-
67349167716
-
Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma
-
Greene VR, Johnson MM, Grimm EA, Ellerhorst JA. Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma. J Invest Dermatol. 2009;129:1483-8.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1483-1488
-
-
Greene, V.R.1
Johnson, M.M.2
Grimm, E.A.3
Ellerhorst, J.A.4
-
131
-
-
0033171035
-
"...those left behind." Biology and oncology of invasive glioma cells
-
Berens ME, Giese A. "...those left behind." Biology and oncology of invasive glioma cells. Neoplasia. 1999;1:208-19.
-
(1999)
Neoplasia
, vol.1
, pp. 208-219
-
-
Berens, M.E.1
Giese, A.2
-
132
-
-
44449113812
-
Getting started in biological pathway construction and analysis
-
Viswanathan GA, Seto J, Patil S, Nudelman G, Sealfon SC. Getting started in biological pathway construction and analysis. PLoS Comput Biol. 2008;4:e16.
-
(2008)
PLoS Comput Biol
, vol.4
-
-
Viswanathan, G.A.1
Seto, J.2
Patil, S.3
Nudelman, G.4
Sealfon, S.C.5
-
133
-
-
80053985343
-
Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer
-
Nagaprashantha LD, Vatsyayan R, Singhal J, Fast S, Roby R, Awasthi S, et al. Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer. Biochem Pharmacol. 2011;82:1100-1109.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 1100-1109
-
-
Nagaprashantha, L.D.1
Vatsyayan, R.2
Singhal, J.3
Fast, S.4
Roby, R.5
Awasthi, S.6
-
134
-
-
77952117909
-
Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines
-
Holbeck SL, Collins JM, Doroshow JH. Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines. Mol Cancer Ther. 2010;9:1451-60.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1451-1460
-
-
Holbeck, S.L.1
Collins, J.M.2
Doroshow, J.H.3
-
136
-
-
65349189958
-
American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
-
Allegra CJ, Jessup JM, Somerfield MR, Hamilton SR, Hammond EH, Hayes DF, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol. 2009;27:2091-6.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2091-2096
-
-
Allegra, C.J.1
Jessup, J.M.2
Somerfield, M.R.3
Hamilton, S.R.4
Hammond, E.H.5
Hayes, D.F.6
|