Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma

Molecular Cancer Therapeutics

Volumn 4, Issue 11, 2005, Pages 1681-1688

  Koul, Dimpy ^a   Shen, Ruijun ^a   Bergh, Sherry ^a   Lu, Yiling ^a   de Groot, John F ^a   Liu, Ta Jen ^a   Mills, Gordon B ^a   Yung, W K Alfred ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH FACTOR RECEPTOR; INTEGRIN LINKED KINASE; INTEGRIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; QLT 0267; SERINE; THREONINE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; CARCINOGENESIS; CELL ASSAY; CELL CYCLE G2 PHASE; CELL GROWTH; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVATION; GENE TARGETING; GLIOBLASTOMA; GLIOMA CELL; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYPOTHESIS; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOTTING, WESTERN; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FIBRONECTINS; G2 PHASE; GLIOBLASTOMA; GLIOMA; HUMANS; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SERINE; SIGNAL TRANSDUCTION; THREONINE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VITRONECTIN;

EID: 28044461715     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-05-0258     Document Type: Article

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