메뉴 건너뛰기




Volumn 11, Issue 6, 2009, Pages 583-593

Cross talk initiated by endothelial cells enhances migration and inhibits anoikis of squamous cell carcinoma cells through STAT3/Akt/ERK signaling

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; NEUTRALIZING ANTIBODY; PROTEIN BCL 2; PROTEIN KINASE B; STAT3 PROTEIN;

EID: 66449127943     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.09266     Document Type: Article
Times cited : (118)

References (52)
  • 1
    • 0036984640 scopus 로고    scopus 로고
    • Role of angiogenesis in tumor growth and metastasis
    • Folkman J (2002). Role of angiogenesis in tumor growth and metastasis. Semin Oncol 29, 15-18.
    • (2002) Semin Oncol , vol.29 , pp. 15-18
    • Folkman, J.1
  • 2
    • 22244460522 scopus 로고    scopus 로고
    • Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling
    • DOI 10.1016/j.ccr.2005.06.004, PII S1535610805001923
    • Zeng Q, Li S, Chepeha DB, Giordano TJ, Li J, Zhang H, Polverini PJ, Nor J, Kitajewski J, and Wang CY (2005). Crosstalk between tumor and endothelial cells promotes tumor angiogenesis by MAPK activation of Notch signaling. Cancer Cell 8, 13-23. (Pubitemid 40991811)
    • (2005) Cancer Cell , vol.8 , Issue.1 , pp. 13-23
    • Zeng, Q.1    Li, S.2    Chepeha, D.B.3    Giordano, T.J.4    Li, J.5    Zhang, H.6    Polverini, P.J.7    Nor, J.8    Kitajewski, J.9    Wang, C.-Y.10
  • 7
    • 1842685093 scopus 로고    scopus 로고
    • Focus on head and neck cancer
    • DOI 10.1016/S1535-6108(04)00090-X, PII S153561080400090X
    • Mao L, Hong WK, and Papadimitrakopoulou VA (2004). Focus on head and neck cancer. Cancer Cell 5, 311-316. (Pubitemid 38482067)
    • (2004) Cancer Cell , vol.5 , Issue.4 , pp. 311-316
    • Mao, L.1    Hong, W.K.2    Papadimitrakopoulou, V.A.3
  • 10
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I and Sawyers CL (2002). The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2, 489-501. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 11
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
    • DOI 10.1016/S1535-6108(03)00248-4
    • Luo J, Manning BD, and Cantley LC (2003). Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4, 257-262. (Pubitemid 37329790)
    • (2003) Cancer Cell , vol.4 , Issue.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3
  • 12
    • 34248591612 scopus 로고    scopus 로고
    • Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
    • DOI 10.1038/sj.onc.1210422, PII 1210422
    • Roberts PJ and Der CJ (2007). Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26, 3291-3310. (Pubitemid 46763022)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3291-3310
    • Roberts, P.J.1    Der, C.J.2
  • 13
    • 38949183695 scopus 로고    scopus 로고
    • Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy
    • Friday BB and Adjei AA (2008). Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy. Clin Cancer Res 14, 342-346.
    • (2008) Clin Cancer Res , vol.14 , pp. 342-346
    • Friday, B.B.1    Adjei, A.A.2
  • 14
    • 0034658499 scopus 로고    scopus 로고
    • STAT signaling in head and neck cancer
    • Song JI and Grandis JR (2000). STAT signaling in head and neck cancer. Oncogene 19, 2489-2495. (Pubitemid 30339204)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2489-2495
    • Song, J.I.1    Grandis, J.R.2
  • 15
    • 0037067672 scopus 로고    scopus 로고
    • Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFκB
    • DOI 10.1074/jbc.M201598200
    • Zeng Q, Chen S, You Z, Yang F, Carey TE, Saims D, and Wang CY (2002). Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa B. J Biol Chem 277, 25203-25208. (Pubitemid 34951827)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.28 , pp. 25203-25208
    • Zeng, Q.1    Chen, S.2    You, Z.3    Yang, F.4    Carey, T.E.5    Saims, D.6    Wang, C.-Y.7
  • 16
    • 0037352170 scopus 로고    scopus 로고
    • Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
    • DOI 10.1038/sj.leu.2402824
    • Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, Franklin RA, and McCubrey JA (2003). Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia 17, 590-603. (Pubitemid 36395654)
    • (2003) Leukemia , vol.17 , Issue.3 , pp. 590-603
    • Chang, F.1    Lee, J.T.2    Navolanic, P.M.3    Steelman, L.S.4    Shelton, J.G.5    Blalock, W.L.6    Franklin, R.A.7    McCubrey, J.A.8
  • 17
    • 0032963472 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
    • Nör JE, Christensen J, Mooney DJ, and Polverini PJ (1999). Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 154, 375-384. (Pubitemid 29094088)
    • (1999) American Journal of Pathology , vol.154 , Issue.2 , pp. 375-384
    • Nor, J.E.1    Christensen, J.2    Mooney, D.J.3    Polverini, P.J.4
  • 18
    • 0035266313 scopus 로고    scopus 로고
    • Up-regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth
    • Nör JE, Christensen J, Liu J, Peters M, Mooney DJ, Strieter RM, and Polverini PJ (2001). Up-regulation of Bcl-2 in microvascular endothelial cells enhances intratumoral angiogenesis and accelerates tumor growth. Cancer Res 61, 2183-2188. (Pubitemid 32692045)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 2183-2188
    • Nor, J.E.1    Christensen, J.2    Liu, J.3    Peters, M.4    Mooney, D.J.5    Strieter, R.M.6    Polverini, P.J.7
  • 21
    • 85047697543 scopus 로고    scopus 로고
    • Ablation of microvessels in vivo upon dimerization of iCaspase-9
    • DOI 10.1038/sj/gt/3301671
    • Nor JE, Hu Y, Song W, Spencer DM, and Nunez G (2002). Ablation of microvessels in vivo upon dimerization of iCaspase-9. Gene Ther 9, 444-451. (Pubitemid 34428753)
    • (2002) Gene Therapy , vol.9 , Issue.7 , pp. 444-451
    • Nor, J.E.1    Hu, Y.2    Song, W.3    Spencer, D.M.4    Nunez, G.5
  • 22
    • 0030680070 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression in head and neck squamous cell carcinoma
    • DOI 10.1016/S0002-9610(97)00166-9, PII S0002961097001669
    • Eisma RJ, Spiro JD, and Kreutzer DL (1997). Vascular endothelial growth factor expression in head and neck squamous cell carcinoma. Am J Surg 174, 513-517. (Pubitemid 27486016)
    • (1997) American Journal of Surgery , vol.174 , Issue.5 , pp. 513-517
    • Eisma, R.J.1    Spiro, J.D.2    Kreutzer, D.L.3
  • 23
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, and Li ZW (2002). NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2, 301-310. (Pubitemid 37328783)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.-W.4
  • 24
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • DOI 10.1038/nature01322
    • Coussens LM and Werb Z (2002). Inflammation and cancer. Nature 420, 860-867. (Pubitemid 36019639)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 25
    • 12344328353 scopus 로고    scopus 로고
    • Tumor-stroma interactions
    • DOI 10.1016/j.gde.2004.12.003, PII S0959437X04001893, Oncogenes and Cell Proliferation
    • Bhowmick NA and Moses HL (2005). Tumor-stroma interactions. Curr Opin Genet Dev 15, 97-101. (Pubitemid 40127637)
    • (2005) Current Opinion in Genetics and Development , vol.15 , Issue.1 , pp. 97-101
    • Bhowmick, N.A.1    Moses, H.L.2
  • 26
    • 61349113394 scopus 로고    scopus 로고
    • Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model
    • Halin S, Rudolfsson SH, Van Rooijen N, and Bergh A (2009). Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model. Neoplasia 11, 177-186.
    • (2009) Neoplasia , vol.11 , pp. 177-186
    • Halin, S.1    Rudolfsson, S.H.2    Van Rooijen, N.3    Bergh, A.4
  • 27
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, and Jove R (2002). Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8, 945-954. (Pubitemid 35177340)
    • (2002) Clinical Cancer Research , vol.8 , Issue.4 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 28
    • 10944245682 scopus 로고    scopus 로고
    • Targeting the STAT pathway in head and neck cancer: Recent advances and future prospects
    • DOI 10.2174/1568009043332736
    • Nikitakis NG, Siavash H, and Sauk JJ (2004). Targeting the STAT pathway in head and neck cancer: recent advances and future prospects. Curr Cancer Drug Targets 4, 637-651. (Pubitemid 40013571)
    • (2004) Current Cancer Drug Targets , vol.4 , Issue.8 , pp. 637-651
    • Nikitakis, N.G.1    Siavash, H.2    Sauk, J.J.3
  • 29
    • 34547975508 scopus 로고    scopus 로고
    • Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma
    • DOI 10.1016/j.oraloncology.2006.10.007, PII S1368837506002818
    • Masuda M, Ruan HY, Ito A, Nakashima T, Toh S, Wakasaki T, Yasumatsu R, Kutratomi Y, Komune S, and Weinstein IB (2007). Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma. Oral Oncol 43, 785-790. (Pubitemid 47271897)
    • (2007) Oral Oncology , vol.43 , Issue.8 , pp. 785-790
    • Masuda, M.1    Ruan, H.-Y.2    Ito, A.3    Nakashima, T.4    Toh, S.5    Wakasaki, T.6    Yasumatsu, R.7    Kutratomi, Y.8    Komune, S.9    Weinstein, I.B.10
  • 30
    • 34548048411 scopus 로고    scopus 로고
    • Analysis of PIK3CA and Akt/protein kinase B in head and neck squamous cell carcinoma
    • Fenic I, Steger K, Gruber C, Arens C, and Woenckhaus J (2007). Analysis of PIK3CA and Akt/protein kinase B in head and neck squamous cell carcinoma. Oncol Rep 18, 253-259.
    • (2007) Oncol Rep , vol.18 , pp. 253-259
    • Fenic, I.1    Steger, K.2    Gruber, C.3    Arens, C.4    Woenckhaus, J.5
  • 31
    • 33846694864 scopus 로고    scopus 로고
    • Activation of Akt predicts poor outcome in neuroblastoma
    • DOI 10.1158/0008-5472.CAN-06-2201
    • Opel D, Poremba C, Simon T, Debatin KM, and Fulda S (2007). Activation of Akt predicts poor outcome in neuroblastoma. Cancer Res 67, 735-745. (Pubitemid 46192214)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 735-745
    • Opel, D.1    Poremba, C.2    Simon, T.3    Debatin, K.-M.4    Fulda, S.5
  • 32
    • 0036314050 scopus 로고    scopus 로고
    • Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma
    • DOI 10.1016/S1368-8375(01)00104-X, PII S136883750100104X
    • Mishima K, Inoue K, and Hayashi Y (2002). Overexpression of extracellular-signal regulated kinases on oral squamous cell carcinoma. Oral Oncol 38, 468-474. (Pubitemid 34756732)
    • (2002) Oral Oncology , vol.38 , Issue.5 , pp. 468-474
    • Mishima, K.1    Inoue, K.2    Hayashi, Y.3
  • 33
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F (2004). Cancer and the chemokine network. Nat Rev Cancer 4, 540-550. (Pubitemid 38868623)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.7 , pp. 540-550
    • Balkwill, F.1
  • 34
    • 0036005889 scopus 로고    scopus 로고
    • Chemokines in cancer
    • DOI 10.1016/S1359-6101(01)00033-8, PII S1359610101000338
    • Vicari AP and Caux C (2002). Chemokines in cancer. Cytokine Growth Factor Rev 13, 143-154. (Pubitemid 34229389)
    • (2002) Cytokine and Growth Factor Reviews , vol.13 , Issue.2 , pp. 143-154
    • Vicari, A.P.1    Caux, C.2
  • 36
  • 37
    • 0034658541 scopus 로고    scopus 로고
    • Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
    • Hirano T, Ishihara K, and Hibi M (2000). Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 19, 2548-2556. (Pubitemid 30339210)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2548-2556
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 38
    • 27544476971 scopus 로고    scopus 로고
    • The role of IL-6 and STAT3 in inflammation and cancer
    • DOI 10.1016/j.ejca.2005.08.016, PII S0959804905007094, Transcription Factors in Cancer
    • Hodge DR, Hurt EM, and Farrar WL (2005). The role of IL-6 and STAT3 in inflammation and cancer. Eur J Cancer 41, 2502-2512. (Pubitemid 41540626)
    • (2005) European Journal of Cancer , vol.41 , Issue.16 , pp. 2502-2512
    • Hodge, D.R.1    Hurt, E.M.2    Farrar, W.L.3
  • 39
    • 33947417336 scopus 로고    scopus 로고
    • Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: Clinical implications
    • DOI 10.1158/1078-0432.CCR-06-2313
    • Huang S (2007). Regulation of metastases by signal transducer and activator of transcription 3 signaling pathway: clinical implications. Clin Cancer Res 13, 1362-1366. (Pubitemid 46450423)
    • (2007) Clinical Cancer Research , vol.13 , Issue.5 , pp. 1362-1366
    • Huang, S.1
  • 40
    • 1542297244 scopus 로고    scopus 로고
    • IL-6 signal transduction and its physiological roles: The signal orchestration model
    • Kamimura D, Ishihara K, and Hirano T (2003). IL-6 signal transduction and its physiological roles: the signal orchestration model. Rev Physiol Biochem Pharmacol 149, 1-38.
    • (2003) Rev Physiol Biochem Pharmacol , vol.149 , pp. 1-38
    • Kamimura, D.1    Ishihara, K.2    Hirano, T.3
  • 41
    • 33749055594 scopus 로고    scopus 로고
    • Molecular cross-talk between the NFκB and STAT3 signaling pathways in head and neck squamous cell carcinoma
    • DOI 10.1593/neo.06274
    • Squarize CH, Castilho RM, Sriuranpong V, Pinto DS Jr, and Gutkind JS (2006). Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma. Neoplasia 8, 733-746. (Pubitemid 44465525)
    • (2006) Neoplasia , vol.8 , Issue.9 , pp. 733-746
    • Squarize, C.H.1    Castilho, R.M.2    Sriuranpong, V.3    Pinto Jr., D.S.4    Gutkind, J.S.5
  • 43
    • 41649121939 scopus 로고    scopus 로고
    • Stimulated monocyte IL-6 secretion predicts survival of patients with head and neck squamous cell carcinoma
    • Heimdal JH, Kross K, Klementsen B, Olofsson J, and Aarstad HJ (2008). Stimulated monocyte IL-6 secretion predicts survival of patients with head and neck squamous cell carcinoma. BMC Cancer 8, 34.
    • (2008) BMC Cancer , vol.8 , pp. 34
    • Heimdal, J.H.1    Kross, K.2    Klementsen, B.3    Olofsson, J.4    Aarstad, H.J.5
  • 46
    • 33745092085 scopus 로고    scopus 로고
    • Mitogenic effects of interleukin-8/CXCL8 on cancer cells
    • Zhu YM and Woll PJ (2005).Mitogenic effects of interleukin-8/CXCL8 on cancer cells. Future Oncol 1, 699-704.
    • (2005) Future Oncol , vol.1 , pp. 699-704
    • Zhu, Y.M.1    Woll, P.J.2
  • 47
    • 16444380479 scopus 로고    scopus 로고
    • KSHV-GPCR and CXCR2 transforming capacity and angiogenic responses are mediated through a JAK2-STAT3-dependent pathway
    • DOI 10.1038/sj.onc.1208442
    • Burger M, Hartmann T, Burger JA, and Schraufstatter I (2005). KSHV-GPCR and CXCR2 transforming capacity and angiogenic responses are mediated through a JAK2-STAT3-dependent pathway. Oncogene 24, 2067-2075. (Pubitemid 40516200)
    • (2005) Oncogene , vol.24 , Issue.12 , pp. 2067-2075
    • Burger, M.1    Hartmann, T.2    Burger, J.A.3    Schraufstatter, I.4
  • 48
    • 14744276549 scopus 로고    scopus 로고
    • Impaired interleukin-8- And GROα-induced phosphorylation of extracellular signal-regulated kinase result in decreased migration of neutrophils from patients with myelodysplasia
    • DOI 10.1189/jlb.0504306
    • Fuhler GM, Knol GJ, Drayer AL, and Vellenga E (2005). Impaired interleukin-8-and GROalpha-induced phosphorylation of extracellular signal-regulated kinase result in decreased migration of neutrophils from patients with myelodysplasia. J Leukoc Biol 77, 257-266. (Pubitemid 40326224)
    • (2005) Journal of Leukocyte Biology , vol.77 , Issue.2 , pp. 257-266
    • Fuhler, G.M.1    Knol, G.J.2    Drayer, A.L.3    Vellenga, E.4
  • 49
    • 0027183870 scopus 로고
    • Elevated levels of transforming growth factor α and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer
    • Grandis JR and Tweardy DJ (1993). Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer. Cancer Res 53, 3579-3584. (Pubitemid 23229640)
    • (1993) Cancer Research , vol.53 , Issue.15 , pp. 3579-3584
    • Grandis, J.R.1    Tweardy, D.J.2
  • 50
    • 0036024855 scopus 로고    scopus 로고
    • STAT3 activation abrogates growth factor dependence and contributes to head and neck squamous cell carcinoma tumor growth in vivo
    • Kijima T, Niwa H, Steinman RA, Drenning SD, Gooding WE, Wentzel AL, Xi S, and Grandis JR (2002). STAT3 activation abrogates growth factor dependence and contributes to head and neck squamous cell carcinoma tumor growth in vivo. Cell Growth Differ 3, 355-362.
    • (2002) Cell Growth Differ , vol.3 , pp. 355-362
    • Kijima, T.1    Niwa, H.2    Steinman, R.A.3    Drenning, S.D.4    Gooding, W.E.5    Wentzel, A.L.6    Xi, S.7    Grandis, J.R.8
  • 51
    • 0038581774 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system
    • Sriuranpong V, Park JI, Amornphimoltham P, Patel V, Nelkin BD, and Gutkind JS (2003). Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system. Cancer Res 63, 2948-2956. (Pubitemid 36667168)
    • (2003) Cancer Research , vol.63 , Issue.11 , pp. 2948-2956
    • Sriuranpong, V.1    Park, J.I.2    Amornphimoltham, P.3    Patel, V.4    Nelkin, B.D.5    Gutkind, J.S.6
  • 52
    • 0142123568 scopus 로고    scopus 로고
    • The molecular biology of mucosal field cancerization of the head and neck
    • Ha PK and Califano JA (2003). The molecular biology of mucosal field cancerization of the head and neck. Crit Rev Oral Biol Med 14, 363-369. (Pubitemid 44560790)
    • (2003) Critical Reviews in Oral Biology and Medicine , vol.14 , Issue.5 , pp. 363-369
    • Ha, P.K.1    Califano, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.