Galectin-3: A novel antiapoptotic molecule with A functional BH1 (NWGR) domain of Bcl-2 family

Cancer Research

Volumn 57, Issue 23, 1997, Pages 5272-5276

  Akahani, Shiro ^a   Nangia Makker, Pratima ^a   Inohara, Hidenori ^a,d   Kim, Hyeong Reh Choi ^b   Raz, Avraham ^a,c  

^a KARMANOS CANCER INSTITUTE   (United States)

^b Department of Pathology ^*  (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GALECTIN 3;

APOPTOSIS; ARTICLE; BREAST CANCER; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; TUMOR GROWTH;

AMINO ACID SEQUENCE; ANTIGENS, DIFFERENTIATION; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BREAST NEOPLASMS; CELL SURVIVAL; CISPLATIN; CONSERVED SEQUENCE; DNA FRAGMENTATION; FEMALE; GALECTIN 3; HUMANS; KINETICS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR CELLS, CULTURED;

EID: 0030707480     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Cress, A. E., and Dalton, W. E. Multiple drug resistance and intermediate filaments. Cancer Metastasis Rev., 15: 499-506, 1996.
2. Barondes, S. H., Castronovo, V., Cooper, D. N. W., Cummings, R. D., Drickamer, K., Fenzi, T., Gitt, M. A., Hirabayashi, J., Hughes, C., Kasai, K., Leffler, H., Liu, F. T., Lotan, R., Mercurio, A. M., Monsigny, M., Pillai, S., Poirer, F., Raz, A., Rigby, P. W. J., Rini, J. M., and Wang, J. L. Galectins: a family of animal β-galactoside-binding lectins. Cell, 76: 597-598, 1994.
3. Gillenwater, A., Xu, XC., El-Naggar, A. K., Clayman, G. L., and Lotan, R. Expression of galectins in head and neck squamous cell carcinoma. Head Neck, 18: 422-432, 1996.
4. Xu, X. C., El-Naggar, A. K., and Lotan, R. Differential expression of galectin-1 and galectin-3 in thyroid tumors. Am. J. Pathol., 147: 815-822, 1995.
5. Lotan, R., Ito, H., Yasui, W., Yokozaki, H., Lotan, D., and Tahara, E. Expression of 31-KDa lactose-binding lectin in normal human gastric mucosa and primary and metastatic gastric carcinomas. Int. J. Cancer, 56: 474-480, 1994.
6. Schoeppner, H. L., Raz, A., Ho, S. B., and Bresalier, R. S. Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon. Cancer (Phila.), 75: 2818-2826, 1995.
7. Raz, A., Zhu, D., Hogan, V., Shah, N., Raz, T., Karkash, R., Pazerini, G., and Carmi, P. Evidence for the role of 34-KDa galactoside-binding lectin in transformation and metastasis. Int. J. Cancer, 46: 871-877, 1990.
8. Nangia-Makker, P., Thompson, E., Hogan, C., Ochieng, J., and Raz, A. Induction of tumorigenicity by galectin-3 in a non-tumorigenic human breast carcinoma cell line. Int. J. Oncol., 7: 1079-1087, 1995.
9. Glinsky, G. V., and Glinsky, V. V. Apoptosis and metastasis: a superior resistance of metastatic cancer cells to programmed cell death. Cancer Lett., 101: 43-51, 1996.
10. Yang, RY., Hsu, D. K., and Liu, F-T. Expression of galectin-3 modulates T-cell growth and apoptosis. Proc. Natl. Acad. Sci. USA., 93: 6737-6742, 1996.
11. Perillo, N. L., Pace, K. E., Seilhamer, J. J., and Baum, L. G. Apoptosis of T cells mediated by galectin-1. Nature (Lond.), 378: 736-739, 1995.
12. Perillo, N. L., Uittenbogaart, C. H., Nguyen, J. T., and Baum, L. G. Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes. J. Exp. Med., 185: 1851-1858, 1997.
13. Wada, J., Ota, K., Kumar, A., Wallner, E. I., and Kanwar, Y. S. Developmental regulation, and apoptotic potential of galectin-9, a β-galactoside binding lectin. J. Clin. Invest., 99: 2452-2461, 1997.
14. Huddart, R. A., Titley, J., Robertson, G. T., Horwich, A., and Cooper, C. S. Programmed cell death in response to chemotherapeutic agents in human germ cell tumor lines. Eur. J. Cancer, 31A: 739-746, 1995.
15. Telford, W. G., King, L. H., and Fraker, P. J. Comparative evaluation of several DNA binding dyes in the detection of apoptosis-associated chromatin degradation by flow cytometry. Cytometry, 13: 137-143, 1992.
16. Oberhammer, F., Wilson, J. W., Dive, C., Morris, I. D., Hickman, J. A., Walkeling, A. E., Walker, P. R., and Sikorska, M. Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J., 12: 3679-3684, 1993.
17. Korsmeyer, S. J. Regulators of cell death. Trends Genet., 11: 101-105, 1995.
18. Zhang Z., Vuori, K., Reed, J. C., and Ruoslahti, E. The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proc. Natl. Acad. Sci. USA, 92: 6161-6165, 1995.
19. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, S., Beidler, D. R., Poirier, G. G., Salveson, G. S., and Dixit, V. M. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell, 81: 801-809, 1995.
20. L inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells. Cancer Res., 56: 4743-4748, 1996.
21. Kaufman, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirier, G. G. Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res., 53: 3976-3985, 1993.
22. Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell. Biol., 124: 1-6, 1994.
23. Fraser, A., and Evan, G. A license to kill. Cell, 85: 781-784, 1996.
24. Hengartner, M. O., and Horvitz, H. R. C. elegans cell survival gene ced-9 encodes a functional homolog of mammalian proto-oncogene bcl-2. Cell, 76: 665-675, 1994.
25. Hengartner, M. O., Ellis, R. E., and Horvitz, H. R. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death. Nature (Lond.), 369: 318-320, 1994.
26. Yin, X. M., Oltvali, Z. N., and Korsmeyer, S. J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature (Lond.), 369: 321-328, 1994.
27. Glinsky, G. V., Mossine, V. V., Price, J. E., Bielenberg, D., and Glinsky, V. V. Inhibition of colony formation in agarose of metastatic human breast carcinoma and melanoma cells by synthetic glycoamine analogs. Clin. Exp. Metastasis, 14: 253-267, 1996.
28. Inohara, H., Akahani, S., Koths, K., and Raz, A. Interactions between galectin-3 and Mac-2-binding protein mediate cell-cell adhesion. Cancer Res., 56: 4530-4534, 1996.
29. Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T-I., Jones, D. P., and Wang, X. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science (Washington DC), 275: 1129-1132, 1997.
30. Kluck, R. M., Bossy-Wetzel, E., Green, D. R., and Newmeyer, D. D. The release of cytochrome from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science (Washington DC), 275: 1132-1136, 1997.