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Volumn 13, Issue 68, 2013, Pages 19-34

Transporter pharmacogenetics: Transporter polymorphisms affect normal physiology, diseases, and pharmacotherapy

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CARRIER PROTEIN;

EID: 84862246184     PISSN: 15396509     EISSN: 19447930     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (53)

References (115)
  • 5
    • 78449260762 scopus 로고    scopus 로고
    • Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians
    • Boivin AA, Cardinal H, Barama A, Pichette V, Hebert MJ, Roger M. Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians. Drug Metab Pharmacokinet 25(5):508-515, 2010.
    • (2010) Drug Metab Pharmacokinet , vol.25 , Issue.5 , pp. 508-515
    • Boivin, A.A.1    Cardinal, H.2    Barama, A.3    Pichette, V.4    Hebert, M.J.5    Roger, M.6
  • 7
    • 33749267293 scopus 로고    scopus 로고
    • Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs
    • Cascorbi I. Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs. Pharmacol Ther 112(2):457-473, 2006.
    • (2006) Pharmacol Ther , vol.112 , Issue.2 , pp. 457-473
    • Cascorbi, I.1
  • 8
    • 0026465461 scopus 로고
    • Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes
    • Chaudhary PM, Mechetner EB, Roninson IB. Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes. Blood 80(11):2735-2739, 1992.
    • (1992) Blood , vol.80 , Issue.11 , pp. 2735-2739
    • Chaudhary, P.M.1    Mechetner, E.B.2    Roninson, I.B.3
  • 9
    • 79959579746 scopus 로고    scopus 로고
    • The effects of CYP3A4, CYP3A5, ABCB1, ABCC2, ABCG2 and SLCO1B3 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of docetaxel in nasopharyngeal carcinoma patients
    • Chew SC, Singh O, Chen X, Ramasamy RD, Kulkarni T, Lee EJ, Tan EH, Lim WT, Chowbay B. The effects of CYP3A4, CYP3A5, ABCB1, ABCC2, ABCG2 and SLCO1B3 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of docetaxel in nasopharyngeal carcinoma patients. Cancer Chemother Pharmacol 67(6):1471-1478, 2011.
    • (2011) Cancer Chemother Pharmacol , vol.67 , Issue.6 , pp. 1471-1478
    • Chew, S.C.1    Singh, O.2    Chen, X.3    Ramasamy, R.D.4    Kulkarni, T.5    Lee, E.J.6    Tan, E.H.7    Lim, W.T.8    Chowbay, B.9
  • 10
    • 56149118632 scopus 로고    scopus 로고
    • Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences
    • Choi MK, Song IS. Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences. Drug Metab Pharmacokinet 23(4):243-253, 2008.
    • (2008) Drug Metab Pharmacokinet , vol.23 , Issue.4 , pp. 243-253
    • Choi, M.K.1    Song, I.S.2
  • 11
    • 33745831231 scopus 로고    scopus 로고
    • Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters
    • Choudhuri S, Klaassen CD. Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters. Int J Toxicol 25(4):231-259, 2006.
    • (2006) Int J Toxicol , vol.25 , Issue.4 , pp. 231-259
    • Choudhuri, S.1    Klaassen, C.D.2
  • 12
    • 79952132912 scopus 로고    scopus 로고
    • Role of organic cation transporters in drug-induced toxicity
    • Ciarimboli G. Role of organic cation transporters in drug-induced toxicity. Expert Opin Drug Metab Toxicol 7(2):159-174, 2011.
    • (2011) Expert Opin Drug Metab Toxicol , vol.7 , Issue.2 , pp. 159-174
    • Ciarimboli, G.1
  • 13
    • 0032793959 scopus 로고    scopus 로고
    • OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
    • Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, Kim RB. OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab Dispos 27(8):866-871, 1999.
    • (1999) Drug Metab Dispos , vol.27 , Issue.8 , pp. 866-871
    • Cvetkovic, M.1    Leake, B.2    Fromm, M.F.3    Wilkinson, G.R.4    Kim, R.B.5
  • 15
    • 13944275994 scopus 로고    scopus 로고
    • Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides
    • Dresser GK, Kim RB, Bailey DG. Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides. Clin Pharmacol Ther 77(3):170-177, 2005.
    • (2005) Clin Pharmacol Ther , vol.77 , Issue.3 , pp. 170-177
    • Dresser, G.K.1    Kim, R.B.2    Bailey, D.G.3
  • 17
    • 12344334846 scopus 로고    scopus 로고
    • Clinical aspects of the MDR1 (ABCB1) gene polymorphism
    • Eichelbaum M, Fromm MF, Schwab M. Clinical aspects of the MDR1 (ABCB1) gene polymorphism. Ther Drug Monit 26(2):180-185, 2004.
    • (2004) Ther Drug Monit , vol.26 , Issue.2 , pp. 180-185
    • Eichelbaum, M.1    Fromm, M.F.2    Schwab, M.3
  • 18
    • 70749149366 scopus 로고    scopus 로고
    • Clopidogrel pharmacogenomics and risk of inadequate platelet inhibition: US FDA recommendations
    • Ellis KJ, Stouffer GA, McLeod HL, Lee CR. Clopidogrel pharmacogenomics and risk of inadequate platelet inhibition: US FDA recommendations. Pharmacogenomics 10(11):1799-1817, 2009.
    • (2009) Pharmacogenomics , vol.10 , Issue.11 , pp. 1799-1817
    • Ellis, K.J.1    Stouffer, G.A.2    McLeod, H.L.3    Lee, C.R.4
  • 24
    • 65649132986 scopus 로고    scopus 로고
    • Pharmacogenetics of the organic anion transporting polypeptide 1A2
    • Franke RM, Scherkenbach LA, Sparreboom A. Pharmacogenetics of the organic anion transporting polypeptide 1A2. Pharmacogenomics 10(3):339-344, 2009.
    • (2009) Pharmacogenomics , vol.10 , Issue.3 , pp. 339-344
    • Franke, R.M.1    Scherkenbach, L.A.2    Sparreboom, A.3
  • 25
    • 3242785620 scopus 로고    scopus 로고
    • Importance of P-glycoprotein at blood-tissue barriers
    • Fromm MF. Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol Sci 25(8):423-429, 2004.
    • (2004) Trends Pharmacol Sci , vol.25 , Issue.8 , pp. 423-429
    • Fromm, M.F.1
  • 26
    • 0023317377 scopus 로고
    • Effect of digoxin-like immunoreactive factor on the TDx digoxin II assay
    • Frye R, Mathews SE. Effect of digoxin-like immunoreactive factor on the TDx digoxin II assay. Clin Chem 33(4):629-630, 1987.
    • (1987) Clin Chem , vol.33 , Issue.4 , pp. 629-630
    • Frye, R.1    Mathews, S.E.2
  • 27
    • 79960148136 scopus 로고    scopus 로고
    • Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins
    • Generaux GT, Bonomo FM, Johnson M, Doan KM. Impact of SLCO1B1 (OATP1B1) and ABCG2 (BCRP) genetic polymorphisms and inhibition on LDL-C lowering and myopathy of statins. Xenobiotica 41(8):639-651, 2011.
    • (2011) Xenobiotica , vol.41 , Issue.8 , pp. 639-651
    • Generaux, G.T.1    Bonomo, F.M.2    Johnson, M.3    Doan, K.M.4
  • 28
    • 40549085349 scopus 로고    scopus 로고
    • Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol
    • Haenisch S, May K, Wegner D, Caliebe A, Cascorbi I, Siegmund W. Influence of genetic polymorphisms on intestinal expression and rifampicin-type induction of ABCC2 and on bioavailability of talinolol. Pharmacogenet Genomics 18(4):357-365, 2008.
    • (2008) Pharmacogenet Genomics , vol.18 , Issue.4 , pp. 357-365
    • Haenisch, S.1    May, K.2    Wegner, D.3    Caliebe, A.4    Cascorbi, I.5    Siegmund, W.6
  • 30
    • 79953314999 scopus 로고    scopus 로고
    • Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCC2 and their impact on drug disposition
    • Haufroid V. Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCC2 and their impact on drug disposition. Curr Drug Targets 12(5):631-646, 2011.
    • (2011) Curr Drug Targets , vol.12 , Issue.5 , pp. 631-646
    • Haufroid, V.1
  • 32
    • 3543004158 scopus 로고    scopus 로고
    • Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2
    • Hirouchi M, Suzuki H, Itoda M, Ozawa S, Sawada J, Ieiri I, Ohtsubo K, Sugiyama Y. Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2. Pharm Res 21(5):742-748, 2004.
    • (2004) Pharm Res , vol.21 , Issue.5 , pp. 742-748
    • Hirouchi, M.1    Suzuki, H.2    Itoda, M.3    Ozawa, S.4    Sawada, J.5    Ieiri, I.6    Ohtsubo, K.7    Sugiyama, Y.8
  • 33
    • 0034971274 scopus 로고    scopus 로고
    • The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
    • Hitzl M, Drescher S, van der Kuip H, Schaffeler E, Fischer J, Schwab M, Eichelbaum M, Fromm MF. The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells. Pharmacogenetics 11(4):293-298, 2001.
    • (2001) Pharmacogenetics , vol.11 , Issue.4 , pp. 293-298
    • Hitzl, M.1    Drescher, S.2    van der Kuip, H.3    Schaffeler, E.4    Fischer, J.5    Schwab, M.6    Eichelbaum, M.7    Fromm, M.F.8
  • 34
    • 14944341671 scopus 로고    scopus 로고
    • Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis
    • Ho GT, Nimmo ER, Tenesa A, Fennell J, Drummond H, Mowat C, Arnott ID, Satsangi J. Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis. Gastroenterology 128(2):288-296, 2005.
    • (2005) Gastroenterology , vol.128 , Issue.2 , pp. 288-296
    • Ho, G.T.1    Nimmo, E.R.2    Tenesa, A.3    Fennell, J.4    Drummond, H.5    Mowat, C.6    Arnott, I.D.7    Satsangi, J.8
  • 35
    • 33144478521 scopus 로고    scopus 로고
    • ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach
    • Ho GT, Soranzo N, Nimmo ER, Tenesa A, Goldstein DB, Satsangi J. ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. Hum Mol Genet 15(5):797-805, 2006.
    • (2006) Hum Mol Genet , vol.15 , Issue.5 , pp. 797-805
    • Ho, G.T.1    Soranzo, N.2    Nimmo, E.R.3    Tenesa, A.4    Goldstein, D.B.5    Satsangi, J.6
  • 37
    • 0038311942 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1)
    • Honjo Y, Morisaki K, Huff LM, Robey RW, Hung J, Dean M, Bates SE. Single-nucleotide polymorphism (SNP) analysis in the ABC half-transporter ABCG2 (MXR/BCRP/ABCP1). Cancer Biol Ther 1(6):696-702, 2002.
    • (2002) Cancer Biol Ther , vol.1 , Issue.6 , pp. 696-702
    • Honjo, Y.1    Morisaki, K.2    Huff, L.M.3    Robey, R.W.4    Hung, J.5    Dean, M.6    Bates, S.E.7
  • 39
    • 0035851106 scopus 로고    scopus 로고
    • Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
    • Ito K, Oleschuk CJ, Westlake C, Vasa MZ, Deeley RG, Cole SP. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity. J Biol Chem 276(41):38108-38114, 2001.
    • (2001) J Biol Chem , vol.276 , Issue.41 , pp. 38108-38114
    • Ito, K.1    Oleschuk, C.J.2    Westlake, C.3    Vasa, M.Z.4    Deeley, R.G.5    Cole, S.P.6
  • 40
    • 0036206860 scopus 로고    scopus 로고
    • Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28
    • Itoda M, Saito Y, Soyama A, Saeki M, Murayama N, Ishida S, Sai K, Nagano M, Suzuki H, Sugiyama Y, Ozawa S, Sawada Ji J. Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: an association between single nucleotide polymorphisms in the 5'-untranslated region and exon 28. Drug Metab Dispos 30(4):363-364, 2002.
    • (2002) Drug Metab Dispos , vol.30 , Issue.4 , pp. 363-364
    • Itoda, M.1    Saito, Y.2    Soyama, A.3    Saeki, M.4    Murayama, N.5    Ishida, S.6    Sai, K.7    Nagano, M.8    Suzuki, H.9    Sugiyama, Y.10    Ozawa, S.11    Sawada Ji, J.12
  • 41
    • 33644698797 scopus 로고    scopus 로고
    • Long-term levothyroxine treatment decreases the oral bioavailability of cyclosporin A by inducing P-glycoprotein in small intestine
    • Jin M, Shimada T, Shintani M, Yokogawa K, Nomura M, Miyamoto K. Long-term levothyroxine treatment decreases the oral bioavailability of cyclosporin A by inducing P-glycoprotein in small intestine. Drug Metab Pharmacokinet 20(5):324-330, 2005.
    • (2005) Drug Metab Pharmacokinet , vol.20 , Issue.5 , pp. 324-330
    • Jin, M.1    Shimada, T.2    Shintani, M.3    Yokogawa, K.4    Nomura, M.5    Miyamoto, K.6
  • 44
    • 58149269041 scopus 로고    scopus 로고
    • Associations between common variants in the MDR1 (ABCB1) gene and ulcerative colitis among North Indians
    • Juyal G, Midha V, Amre D, Sood A, Seidman E, Thelma BK. Associations between common variants in the MDR1 (ABCB1) gene and ulcerative colitis among North Indians. Pharmacogenet Genomics 19(1):77-85, 2009.
    • (2009) Pharmacogenet Genomics , vol.19 , Issue.1 , pp. 77-85
    • Juyal, G.1    Midha, V.2    Amre, D.3    Sood, A.4    Seidman, E.5    Thelma, B.K.6
  • 47
    • 34249742090 scopus 로고    scopus 로고
    • Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy
    • Kock K, Grube M, Jedlitschky G, Oevermann L, Siegmund W, Ritter CA, Kroemer HK. Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy. Clin Pharmacokinet 46(6):449-470, 2007.
    • (2007) Clin Pharmacokinet , vol.46 , Issue.6 , pp. 449-470
    • Kock, K.1    Grube, M.2    Jedlitschky, G.3    Oevermann, L.4    Siegmund, W.5    Ritter, C.A.6    Kroemer, H.K.7
  • 50
    • 17544368685 scopus 로고    scopus 로고
    • Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
    • Leslie EM, Deeley RG, Cole SP. Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. Toxicol Appl Pharmacol 204(3):216-237, 2005.
    • (2005) Toxicol Appl Pharmacol , vol.204 , Issue.3 , pp. 216-237
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 51
    • 23444447815 scopus 로고    scopus 로고
    • Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1)
    • Letourneau IJ, Deeley RG, Cole SP. Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1). Pharmacogenet Genomics 15(9):647-657, 2005.
    • (2005) Pharmacogenet Genomics , vol.15 , Issue.9 , pp. 647-657
    • Letourneau, I.J.1    Deeley, R.G.2    Cole, S.P.3
  • 52
    • 3242765929 scopus 로고    scopus 로고
    • Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8)
    • Letschert K, Keppler D, Konig J. Mutations in the SLCO1B3 gene affecting the substrate specificity of the hepatocellular uptake transporter OATP1B3 (OATP8). Pharmacogenetics 14(7):441-452, 2004.
    • (2004) Pharmacogenetics , vol.14 , Issue.7 , pp. 441-452
    • Letschert, K.1    Keppler, D.2    Konig, J.3
  • 53
    • 77950635502 scopus 로고    scopus 로고
    • Pharmacogenetics in breast cancer: focus on hormone therapy, taxanes, trastuzumab and bevacizumab
    • Longo R, D'Andrea M, Sarmiento R, Gasparini G. Pharmacogenetics in breast cancer: focus on hormone therapy, taxanes, trastuzumab and bevacizumab. Expert Opin Investig Drugs 19(Suppl 1):S41-S50, 2010.
    • (2010) Expert Opin Investig Drugs , vol.19 , Issue.SUPPL 1
    • Longo, R.1    D'Andrea, M.2    Sarmiento, R.3    Gasparini, G.4
  • 55
    • 77958105401 scopus 로고    scopus 로고
    • Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis
    • Mega JL, Close SL, Wiviott SD, Shen L, Walker JR, Simon T, Antman EM, Braunwald E, Sabatine MS. Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis. Lancet 376(9749):1312-1319, 2010.
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1312-1319
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3    Shen, L.4    Walker, J.R.5    Simon, T.6    Antman, E.M.7    Braunwald, E.8    Sabatine, M.S.9
  • 58
    • 77950852256 scopus 로고    scopus 로고
    • Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms
    • Meyerzu Schwabedissen HE, Verstuyft C, Kroemer HK, Becquemont L, Kim RB. Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms. Am J Physiol Renal Physiol 298(4):F997-F1005, 2010.
    • (2010) Am J Physiol Renal Physiol , vol.298 , Issue.4
    • Meyerzu Schwabedissen, H.E.1    Verstuyft, C.2    Kroemer, H.K.3    Becquemont, L.4    Kim, R.B.5
  • 59
    • 77953687856 scopus 로고    scopus 로고
    • Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier
    • Miller DS. Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier. Trends Pharmacol Sci 31(6):246-254, 2010.
    • (2010) Trends Pharmacol Sci , vol.31 , Issue.6 , pp. 246-254
    • Miller, D.S.1
  • 60
    • 79960771381 scopus 로고    scopus 로고
    • Transporter-mediated drug-drug interactions
    • Muller F, Fromm MF. Transporter-mediated drug-drug interactions. Pharmacogenomics 12(7):1017-1037, 2011.
    • (2011) Pharmacogenomics , vol.12 , Issue.7 , pp. 1017-1037
    • Muller, F.1    Fromm, M.F.2
  • 61
    • 79953803082 scopus 로고    scopus 로고
    • ATP-binding cassette efflux transporters in human placenta
    • Ni Z, Mao Q. ATP-binding cassette efflux transporters in human placenta. Curr Pharm Biotechnol 12(4):674-685, 2011.
    • (2011) Curr Pharm Biotechnol , vol.12 , Issue.4 , pp. 674-685
    • Ni, Z.1    Mao, Q.2
  • 62
    • 72849141790 scopus 로고    scopus 로고
    • Transporter pharmacogenetics and statin toxicity
    • Niemi M. Transporter pharmacogenetics and statin toxicity. Clin Pharmacol Ther 87(1):130-133, 2010.
    • (2010) Clin Pharmacol Ther , vol.87 , Issue.1 , pp. 130-133
    • Niemi, M.1
  • 64
    • 79953901458 scopus 로고    scopus 로고
    • Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake
    • Niemi M, Pasanen MK, Neuvonen PJ. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake. Pharmacol Rev 63(1):157-181, 2011.
    • (2011) Pharmacol Rev , vol.63 , Issue.1 , pp. 157-181
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3
  • 65
    • 79953901458 scopus 로고    scopus 로고
    • Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake
    • Niemi M, Pasanen MK, Neuvonen PJ. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake. Pharmacol Rev 63(1):157-181, 2011.
    • (2011) Pharmacol Rev , vol.63 , Issue.1 , pp. 157-181
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3
  • 67
    • 33646757531 scopus 로고    scopus 로고
    • Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study
    • Onnie CM, Fisher SA, Pattni R, Sanderson J, Forbes A, Lewis CM, Mathew CG. Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: a case-control and meta-analysis study. Inflamm Bowel Dis 12(4):263-271, 2006.
    • (2006) Inflamm Bowel Dis , vol.12 , Issue.4 , pp. 263-271
    • Onnie, C.M.1    Fisher, S.A.2    Pattni, R.3    Sanderson, J.4    Forbes, A.5    Lewis, C.M.6    Mathew, C.G.7
  • 72
    • 40949126593 scopus 로고    scopus 로고
    • Global analysis of genetic variation in SLCO1B1
    • Pasanen MK, Neuvonen PJ, Niemi M. Global analysis of genetic variation in SLCO1B1. Pharmacogenomics 9(1):19-33, 2008.
    • (2008) Pharmacogenomics , vol.9 , Issue.1 , pp. 19-33
    • Pasanen, M.K.1    Neuvonen, P.J.2    Niemi, M.3
  • 73
    • 0028301348 scopus 로고
    • Macromolecular permeability across the blood-nerve and blood-brain barriers
    • Poduslo JF, Curran GL, Berg CT. Macromolecular permeability across the blood-nerve and blood-brain barriers. Proc Natl Acad Sci U S A 91(12):5705-5709, 1994.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.12 , pp. 5705-5709
    • Poduslo, J.F.1    Curran, G.L.2    Berg, C.T.3
  • 75
    • 79956268032 scopus 로고    scopus 로고
    • Expression of OATP family members in hormone-related cancers: potential markers of progression
    • Pressler H, Sissung TM, Venzon D, Price DK, Figg WD. Expression of OATP family members in hormone-related cancers: potential markers of progression. PLoS One 6(5):e20372, 2011.
    • (2011) PLoS One , vol.6 , Issue.5
    • Pressler, H.1    Sissung, T.M.2    Venzon, D.3    Price, D.K.4    Figg, W.D.5
  • 76
    • 0033616684 scopus 로고    scopus 로고
    • Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier
    • Rao VV, Dahlheimer JL, Bardgett ME, Snyder AZ, Finch RA, Sartorelli AC, Piwnica-Worms D. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Proc Natl Acad Sci U S A 96(7):3900-3905, 1999.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.7 , pp. 3900-3905
    • Rao, V.V.1    Dahlheimer, J.L.2    Bardgett, M.E.3    Snyder, A.Z.4    Finch, R.A.5    Sartorelli, A.C.6    Piwnica-Worms, D.7
  • 79
    • 77951269333 scopus 로고    scopus 로고
    • Efflux and uptake transporters as determinants of statin response
    • Rodrigues AC. Efflux and uptake transporters as determinants of statin response. Expert Opin Drug Metab Toxicol 6(5):621-632, 2010.
    • (2010) Expert Opin Drug Metab Toxicol , vol.6 , Issue.5 , pp. 621-632
    • Rodrigues, A.C.1
  • 80
    • 0034740948 scopus 로고    scopus 로고
    • Homozygous disruption of the mdrla P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs
    • Saito T, Zhang ZJ, Ohtsubo T, Noda I, Shibamori Y, Yamamoto T, Saito H. Homozygous disruption of the mdrla P-glycoprotein gene affects blood-nerve barrier function in mice administered with neurotoxic drugs. Acta Otolaryngol 121(6):735-742, 2001.
    • (2001) Acta Otolaryngol , vol.121 , Issue.6 , pp. 735-742
    • Saito, T.1    Zhang, Z.J.2    Ohtsubo, T.3    Noda, I.4    Shibamori, Y.5    Yamamoto, T.6    Saito, H.7
  • 81
    • 32044455207 scopus 로고    scopus 로고
    • MDR1 genotype-related pharmacokinetics: fact or fiction?
    • Sakaeda T. MDR1 genotype-related pharmacokinetics: fact or fiction? Drug Metab Pharmacokinet 20(6):391-414, 2005.
    • (2005) Drug Metab Pharmacokinet , vol.20 , Issue.6 , pp. 391-414
    • Sakaeda, T.1
  • 86
    • 84856271899 scopus 로고    scopus 로고
    • The P-glycoprotein multidrug transporter
    • Sharom FJ. The P-glycoprotein multidrug transporter. Essays Biochem 50(1):161-178, 2011.
    • (2011) Essays Biochem , vol.50 , Issue.1 , pp. 161-178
    • Sharom, F.J.1
  • 87
    • 0034816905 scopus 로고    scopus 로고
    • Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells
    • Shu Y, Bello CL, Mangravite LM, Feng B, Giacomini KM. Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells. J Pharmacol Exp Ther 299(1):392-398, 2001.
    • (2001) J Pharmacol Exp Ther , vol.299 , Issue.1 , pp. 392-398
    • Shu, Y.1    Bello, C.L.2    Mangravite, L.M.3    Feng, B.4    Giacomini, K.M.5
  • 90
    • 51649129871 scopus 로고    scopus 로고
    • ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen-independent prostate cancer treated with docetaxel
    • Sissung TM, Baum CE, Deeken J, Price DK, Aragon-Ching J, Steinberg SM, Dahut W, Sparreboom A, Figg WD. ABCB1 genetic variation influences the toxicity and clinical outcome of patients with androgen-independent prostate cancer treated with docetaxel. Clin Cancer Res 14(14):4543-4549, 2008.
    • (2008) Clin Cancer Res , vol.14 , Issue.14 , pp. 4543-4549
    • Sissung, T.M.1    Baum, C.E.2    Deeken, J.3    Price, D.K.4    Aragon-Ching, J.5    Steinberg, S.M.6    Dahut, W.7    Sparreboom, A.8    Figg, W.D.9
  • 94
    • 0037131880 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition
    • Suzuki H, Sugiyama Y. Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition. Adv Drug Deliv Rev 54(10):1311-1331, 2002.
    • (2002) Adv Drug Deliv Rev , vol.54 , Issue.10 , pp. 1311-1331
    • Suzuki, H.1    Sugiyama, Y.2
  • 95
    • 79952809873 scopus 로고    scopus 로고
    • Organic anion transporting polypeptides (OATPs): regulation of expression and function
    • Svoboda M, Riha J, Wlcek K, Jaeger W, Thalhammer T. Organic anion transporting polypeptides (OATPs): regulation of expression and function. Curr Drug Metab 12(2):139-153, 2011.
    • (2011) Curr Drug Metab , vol.12 , Issue.2 , pp. 139-153
    • Svoboda, M.1    Riha, J.2    Wlcek, K.3    Jaeger, W.4    Thalhammer, T.5
  • 96
    • 58149306052 scopus 로고    scopus 로고
    • Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells
    • Tahara K, Kagawa Y, Takaai M, Taguchi M, Hashimoto Y. Directional transcellular transport of bisoprolol in P-glycoprotein-expressed LLC-GA5-COL150 cells, but not in renal epithelial LLC-PK1 Cells. Drug Metab Pharmacokinet 23(5):340-346, 2008.
    • (2008) Drug Metab Pharmacokinet , vol.23 , Issue.5 , pp. 340-346
    • Tahara, K.1    Kagawa, Y.2    Takaai, M.3    Taguchi, M.4    Hashimoto, Y.5
  • 97
    • 44949087480 scopus 로고    scopus 로고
    • Polymorphism in human organic cation transporters and metformin action
    • Takane H, Shikata E, Otsubo K, Higuchi S, Ieiri I. Polymorphism in human organic cation transporters and metformin action. Pharmacogenomics 9(4):415-422, 2008.
    • (2008) Pharmacogenomics , vol.9 , Issue.4 , pp. 415-422
    • Takane, H.1    Shikata, E.2    Otsubo, K.3    Higuchi, S.4    Ieiri, I.5
  • 99
    • 78649657340 scopus 로고    scopus 로고
    • Molecular mechanisms of drug transporter regulation
    • Tirona RG. Molecular mechanisms of drug transporter regulation. Handb Exp Pharmacol (201):373-402, 2011.
    • (2011) Handb Exp Pharmacol , Issue.201 , pp. 373-402
    • Tirona, R.G.1
  • 100
    • 0035929574 scopus 로고    scopus 로고
    • Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
    • Tirona RG, Leake BF, Merino G, Kim RB. Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J Biol Chem 276(38):35669-35675, 2001.
    • (2001) J Biol Chem , vol.276 , Issue.38 , pp. 35669-35675
    • Tirona, R.G.1    Leake, B.F.2    Merino, G.3    Kim, R.B.4
  • 102
    • 79953804775 scopus 로고    scopus 로고
    • ABC proteins protect the human body and maintain optimal health
    • Ueda K. ABC proteins protect the human body and maintain optimal health. Biosci Biotechnol Biochem 75(3):401-409, 2011.
    • (2011) Biosci Biotechnol Biochem , vol.75 , Issue.3 , pp. 401-409
    • Ueda, K.1
  • 107
    • 77958100874 scopus 로고    scopus 로고
    • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial
    • Wallentin L, James S, Storey RF, Armstrong M, Barratt BJ, Horrow J, Husted S, Katus H, Steg PG, Shah SH, Becker RC. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet 376(9749):1320-1328, 2010.
    • (2010) Lancet , vol.376 , Issue.9749 , pp. 1320-1328
    • Wallentin, L.1    James, S.2    Storey, R.F.3    Armstrong, M.4    Barratt, B.J.5    Horrow, J.6    Husted, S.7    Katus, H.8    Steg, P.G.9    Shah, S.H.10    Becker, R.C.11
  • 108
    • 26444438734 scopus 로고    scopus 로고
    • A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection
    • Wang Z, Wang B, Tang K, Lee EJ, Chong SS, Lee CG. A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection. Hum Mol Genet 14(14):2075-2087, 2005.
    • (2005) Hum Mol Genet , vol.14 , Issue.14 , pp. 2075-2087
    • Wang, Z.1    Wang, B.2    Tang, K.3    Lee, E.J.4    Chong, S.S.5    Lee, C.G.6
  • 109
    • 53049095113 scopus 로고    scopus 로고
    • OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine
    • Wang ZJ, Yin OQ, Tomlinson B, Chow MS. OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine. Pharmacogenet Genomics 18(7):637-645, 2008.
    • (2008) Pharmacogenet Genomics , vol.18 , Issue.7 , pp. 637-645
    • Wang, Z.J.1    Yin, O.Q.2    Tomlinson, B.3    Chow, M.S.4
  • 110
    • 0020570136 scopus 로고
    • Effect of thyrotoxicosis on liver blood flow and propranolol disposition after long-term dosing
    • Wells PG, Feely J, Wilkinson GR, Wood AJ. Effect of thyrotoxicosis on liver blood flow and propranolol disposition after long-term dosing. Clin Pharmacol Ther 33(5):603-608, 1983.
    • (1983) Clin Pharmacol Ther , vol.33 , Issue.5 , pp. 603-608
    • Wells, P.G.1    Feely, J.2    Wilkinson, G.R.3    Wood, A.J.4
  • 111
    • 80053561984 scopus 로고    scopus 로고
    • An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics
    • Wolf SJ, Bachtiar M, Wang J, Sim TS, Chong SS, Lee CG. An update on ABCB1 pharmacogenetics: insights from a 3D model into the location and evolutionary conservation of residues corresponding to SNPs associated with drug pharmacokinetics. Pharmacogenomics J 11(5):315-325, 2011.
    • (2011) Pharmacogenomics J , vol.11 , Issue.5 , pp. 315-325
    • Wolf, S.J.1    Bachtiar, M.2    Wang, J.3    Sim, T.S.4    Chong, S.S.5    Lee, C.G.6
  • 115
    • 66449110827 scopus 로고    scopus 로고
    • The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice
    • Zhou L, Schmidt K, Nelson FR, Zelesky V, Troutman MD, Feng B. The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol, imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)propanoic acid (PF-407288) in mice. Drug Metab Dispos 37(5):946-955, 2009.
    • (2009) Drug Metab DisposS , vol.37 , Issue.5 , pp. 946-955
    • Zhou, L.1    Schmidt, K.2    Nelson, F.R.3    Zelesky, V.4    Troutman, M.D.5    Feng, B.6


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