메뉴 건너뛰기




Volumn 12, Issue 4, 2006, Pages 263-271

Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: A case-control and meta-analysis study

Author keywords

Association; Crohn's disease; Genetics; Meta analysis; Ulcerative colitis

Indexed keywords

ABC TRANSPORTER;

EID: 33646757531     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/01.MIB.0000209791.98866.ba     Document Type: Article
Times cited : (78)

References (38)
  • 1
    • 2442563304 scopus 로고    scopus 로고
    • Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
    • Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology. 2004;126:1504-1517.
    • (2004) Gastroenterology , vol.126 , pp. 1504-1517
    • Loftus Jr., E.V.1
  • 2
    • 0037240425 scopus 로고    scopus 로고
    • Clinical applications of advances in the genetics of IBD
    • Sartor RB. Clinical applications of advances in the genetics of IBD. Rev Gastro Dis. 2003;3:S9-S17.
    • (2003) Rev Gastro Dis , vol.3
    • Sartor, R.B.1
  • 3
    • 0024571195 scopus 로고
    • The genetics of Crohn disease: Complex segregation analysis of a family study with 265 patients with Crohn disease and 5,387 relatives
    • Kuster W, Pascoe L, Purrmann J, et al. The genetics of Crohn disease: complex segregation analysis of a family study with 265 patients with Crohn disease and 5,387 relatives. Am J Med Genet. 1989;32:105-108.
    • (1989) Am J Med Genet , vol.32 , pp. 105-108
    • Kuster, W.1    Pascoe, L.2    Purrmann, J.3
  • 4
    • 0026650949 scopus 로고
    • Familial aggregation of inflammatory bowel disease in northern Italy: A multicenter study: The Gruppo di Studio per le Malattie Infiammatorie Intestinali (IBD Study Group)
    • Meucci G, Vecchi M, Torgano G, et al. Familial aggregation of inflammatory bowel disease in northern Italy: a multicenter study: the Gruppo di Studio per le Malattie Infiammatorie Intestinali (IBD Study Group). Gastroenterology. 1992;103:514-519.
    • (1992) Gastroenterology , vol.103 , pp. 514-519
    • Meucci, G.1    Vecchi, M.2    Torgano, G.3
  • 5
    • 0025966488 scopus 로고
    • Familial occurrence of inflammatory bowel disease
    • Orholm M, Munkholm P, Langholz E, et al. Familial occurrence of inflammatory bowel disease. N Engl J Med. 1991;324:84-88.
    • (1991) N Engl J Med , vol.324 , pp. 84-88
    • Orholm, M.1    Munkholm, P.2    Langholz, E.3
  • 6
    • 11144354272 scopus 로고    scopus 로고
    • Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs
    • van Heel DA, Fisher SA, Kirby A, et al. Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum Mol Genet. 2004;13:763-770.
    • (2004) Hum Mol Genet , vol.13 , pp. 763-770
    • Van Heel, D.A.1    Fisher, S.A.2    Kirby, A.3
  • 7
    • 0032534043 scopus 로고    scopus 로고
    • A novel model of inflammatory bowel disease: Mice deficient for the multiple drug resistance gene, mdrla, spontaneously develop colitis
    • Panwala CM, Jones JC, Viney JL. A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdrla, spontaneously develop colitis. J Immunol. 1998;161:5733-5744.
    • (1998) J Immunol , vol.161 , pp. 5733-5744
    • Panwala, C.M.1    Jones, J.C.2    Viney, J.L.3
  • 8
    • 0032499771 scopus 로고    scopus 로고
    • The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis
    • Smyth MJ, Krasovski E, Sutton VR, et al. The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis. Proc Natl Acad Sci U S A. 1998;95:7024-7029.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 7024-7029
    • Smyth, M.J.1    Krasovski, E.2    Sutton, V.R.3
  • 9
    • 0032499681 scopus 로고    scopus 로고
    • A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
    • Randolph GJ, Beaulieu S, Pope M, et al. A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels. Proc Natl Acad Sci U S A. 1998;95:6924-6929.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6924-6929
    • Randolph, G.J.1    Beaulieu, S.2    Pope, M.3
  • 10
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci U S A. 2000;97:3473-3478.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    Von Richter, O.3
  • 11
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther. 2001;70:189-199.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3
  • 12
    • 0035104031 scopus 로고    scopus 로고
    • Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
    • Cascorbi I, Gerloff T, Johne A, et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther. 2001;69:169-174.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 169-174
    • Cascorbi, I.1    Gerloff, T.2    Johne, A.3
  • 13
    • 0037223561 scopus 로고    scopus 로고
    • Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis
    • Schwab M, Schaeffeler E, Marx C, et al. Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis. Gastroenterology. 2003;124:26-33.
    • (2003) Gastroenterology , vol.124 , pp. 26-33
    • Schwab, M.1    Schaeffeler, E.2    Marx, C.3
  • 14
    • 8844229534 scopus 로고    scopus 로고
    • Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
    • Potocnik U, Ferkolj I, Glavac D, et al. Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis. Genes Immun. 2004;5:530-539.
    • (2004) Genes Immun , vol.5 , pp. 530-539
    • Potocnik, U.1    Ferkolj, I.2    Glavac, D.3
  • 15
    • 14944341671 scopus 로고    scopus 로고
    • Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis
    • Ho GT, Nimmo ER, Tenesa A, et al. Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis. Gastroenterology. 2005;128:288-296.
    • (2005) Gastroenterology , vol.128 , pp. 288-296
    • Ho, G.T.1    Nimmo, E.R.2    Tenesa, A.3
  • 16
    • 0344197096 scopus 로고    scopus 로고
    • Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations
    • Croucher PJ, Mascheretti S, Foelsch UR, et al. Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations. Gastroenterology. 2003;125:1919-1920.
    • (2003) Gastroenterology , vol.125 , pp. 1919-1920
    • Croucher, P.J.1    Mascheretti, S.2    Foelsch, U.R.3
  • 17
    • 9144224852 scopus 로고    scopus 로고
    • MDR1 Ala893 polymorphism is associated with inflammatory bowel disease
    • Brant SR, Panhuysen CI, Nicolae D, et al. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am J Hum Genet. 2003;73:1282-1292.
    • (2003) Am J Hum Genet , vol.73 , pp. 1282-1292
    • Brant, S.R.1    Panhuysen, C.I.2    Nicolae, D.3
  • 18
    • 0024810567 scopus 로고
    • Classification of inflammatory bowel disease
    • Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol. 1989;170:2-6.
    • (1989) Scand J Gastroenterol , vol.170 , pp. 2-6
    • Lennard-Jones, J.E.1
  • 19
    • 0026432216 scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med. 1991;325:928-937.
    • (1991) N Engl J Med , vol.325 , pp. 928-937
    • Podolsky, D.K.1
  • 20
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol. 2003;25:111-115.
    • (2003) Genet Epidemiol , vol.25 , pp. 111-115
    • Dudbridge, F.1
  • 21
    • 0002907949 scopus 로고
    • The interaction of selection and linkage, I: General considerations; heterotic models
    • Lewontin RC. The interaction of selection and linkage, I: general considerations; heterotic models. Genetics. 1964;49:49-67.
    • (1964) Genetics , vol.49 , pp. 49-67
    • Lewontin, R.C.1
  • 22
    • 0023430504 scopus 로고
    • Gametic disequilibrium measures: Proceed with caution
    • Hedrick P. Gametic disequilibrium measures: proceed with caution. Genetics. 1987;117:331-341.
    • (1987) Genetics , vol.117 , pp. 331-341
    • Hedrick, P.1
  • 23
    • 0034017850 scopus 로고    scopus 로고
    • GOLD: Graphical overview of linkage disequilibrium
    • Abecasis GR, Cookson WOC. GOLD: graphical overview of linkage disequilibrium. Bioinformatics. 2000;16:182-183.
    • (2000) Bioinformatics , vol.16 , pp. 182-183
    • Abecasis, G.R.1    Cookson, W.O.C.2
  • 24
    • 0346100570 scopus 로고    scopus 로고
    • The C3435T MDR1 gene polymorphism is not associated with susceptibility for ulcerative colitis in Greek population
    • Gazouli M, Zacharatos P, Gorgoulis V, et al. The C3435T MDR1 gene polymorphism is not associated with susceptibility for ulcerative colitis in Greek population. Gastroenterology. 2004;126:367-369.
    • (2004) Gastroenterology , vol.126 , pp. 367-369
    • Gazouli, M.1    Zacharatos, P.2    Gorgoulis, V.3
  • 28
    • 41049093347 scopus 로고
    • The combination of estimates from different experiments
    • Cochran WG. The combination of estimates from different experiments. Biometrics. 1954;10:101-129.
    • (1954) Biometrics , vol.10 , pp. 101-129
    • Cochran, W.G.1
  • 29
    • 1942421704 scopus 로고    scopus 로고
    • Genomic evidence for recent positive selection at the human MDR1 gene locus
    • Tang K, Wong LP, Lee EJ, et al. Genomic evidence for recent positive selection at the human MDR1 gene locus. Hum Mol Genet. 2004;13:783-797.
    • (2004) Hum Mol Genet , vol.13 , pp. 783-797
    • Tang, K.1    Wong, L.P.2    Lee, E.J.3
  • 30
    • 9644263928 scopus 로고    scopus 로고
    • Genotype and allele frequencies of C3435T polymorphism of the MDR1 gene in various Jewish populations of Israel
    • Ostrovsky O, Nagler A, Korostishevsky M, et al. Genotype and allele frequencies of C3435T polymorphism of the MDR1 gene in various Jewish populations of Israel. Ther Drug Monit. 2004;26:679-684.
    • (2004) Ther Drug Monit , vol.26 , pp. 679-684
    • Ostrovsky, O.1    Nagler, A.2    Korostishevsky, M.3
  • 31
    • 0347416889 scopus 로고    scopus 로고
    • MDR1 gene polymorphism in ulcerative colitis
    • Glas J, Torok HP, Schiemann U, et al. MDR1 gene polymorphism in ulcerative colitis. Gastroenterology. 2004;126:367.
    • (2004) Gastroenterology , vol.126 , pp. 367
    • Glas, J.1    Torok, H.P.2    Schiemann, U.3
  • 32
    • 0035179971 scopus 로고    scopus 로고
    • Replication validity of genetic association studies
    • Ioannidis JPA, Ntzani EE, Trikalinos TA, et al. Replication validity of genetic association studies. Nat Genet. 2001;29:306-309.
    • (2001) Nat Genet , vol.29 , pp. 306-309
    • Ioannidis, J.P.A.1    Ntzani, E.E.2    Trikalinos, T.A.3
  • 33
    • 0023553611 scopus 로고
    • Change in the extent of colonic involvement in ulcerative colitis: A colonoscopic study
    • Niv Y, Bat L, Ron E, et al. Change in the extent of colonic involvement in ulcerative colitis: a colonoscopic study. Am J Gastroenterol. 1987;82:1046-1051.
    • (1987) Am J Gastroenterol , vol.82 , pp. 1046-1051
    • Niv, Y.1    Bat, L.2    Ron, E.3
  • 34
    • 0032975986 scopus 로고    scopus 로고
    • Change in the extent of colonoscopic and histological involvement in ulcerative colitis over time
    • Moum B, Ekbom A, Vatn MH, et al. Change in the extent of colonoscopic and histological involvement in ulcerative colitis over time. Am J Gastroenterol. 1999;94:1564-1569.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1564-1569
    • Moum, B.1    Ekbom, A.2    Vatn, M.H.3
  • 35
    • 0033959944 scopus 로고    scopus 로고
    • High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy
    • Farrell RJ, Murphy A, Long A, et al. High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy. Gastroenterology. 2000;118:279-288.
    • (2000) Gastroenterology , vol.118 , pp. 279-288
    • Farrell, R.J.1    Murphy, A.2    Long, A.3
  • 36
    • 0036082545 scopus 로고    scopus 로고
    • Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system
    • Kimchi-Sarfaty C, Gribar JJ, Gottesman MM. Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system. Mol Pharmacol. 2002;62:1-6.
    • (2002) Mol Pharmacol , vol.62 , pp. 1-6
    • Kimchi-Sarfaty, C.1    Gribar, J.J.2    Gottesman, M.M.3
  • 37
    • 25144433260 scopus 로고    scopus 로고
    • Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
    • Wang D, Johnson AD, Papp AC, et al. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genomics. 2005;15:693-703.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 693-703
    • Wang, D.1    Johnson, A.D.2    Papp, A.C.3
  • 38
    • 27644553050 scopus 로고    scopus 로고
    • Multidrug resistance (MDR1) gene in inflammatory bowel disease: Key player?
    • Ho GT, Gaya DR, Satsangi J. Multidrug resistance (MDR1) gene in inflammatory bowel disease: key player? Inflamm Bowel Dis. 2005;11:1013-1019.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 1013-1019
    • Ho, G.T.1    Gaya, D.R.2    Satsangi, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.