-
1
-
-
0033668248
-
High incidence of adriamycin cardiotoxicity in children even at low cumulative doses: Role of radionuclide cardiac angiography
-
Agarwala S, Kumar R, Bhatnagar V, Bajpai M, Gupta DK, Mitra DK (2000) High incidence of adriamycin cardiotoxicity in children even at low cumulative doses: role of radionuclide cardiac angiography. J Pediatr Surg 35:1786-1789
-
(2000)
J Pediatr Surg
, vol.35
, pp. 1786-1789
-
-
Agarwala, S.1
Kumar, R.2
Bhatnagar, V.3
Bajpai, M.4
Gupta, D.K.5
Mitra, D.K.6
-
2
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Schaeffeler E, et al. (2001) Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 69:169-174
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
Meisel, C.4
Hoffmeyer, S.5
Schwab, M.6
Schaeffeler, E.7
-
3
-
-
0027102401
-
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin
-
de Lannoy IA, Silverman M (1992) The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin. Biochem Biophys Res Commun 189:551-557
-
(1992)
Biochem Biophys Res Commun
, vol.189
, pp. 551-557
-
-
De Lannoy, I.A.1
Silverman, M.2
-
4
-
-
0023239684
-
Prescribing digoxin in geriatric units: The unexplained variability in dosage requirements
-
Dobbs RJ, Royston JP, O'Neill CJ, Deshmukh AA, Nicholson PW, Denham MJ, Dobbs SM (1987) Prescribing digoxin in geriatric units: the unexplained variability in dosage requirements. Eur J Clin Pharmacol 32:611-614
-
(1987)
Eur J Clin Pharmacol
, vol.32
, pp. 611-614
-
-
Dobbs, R.J.1
Royston, J.P.2
O'Neill, C.J.3
Deshmukh, A.A.4
Nicholson, P.W.5
Denham, M.J.6
Dobbs, S.M.7
-
5
-
-
9544240355
-
Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes
-
Drach J, Gsur A, Hamilton G, Zhao S, Angerler J, Fiegl M, Zojer N, et al. (1996) Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes. Blood 88:1747-1754
-
(1996)
Blood
, vol.88
, pp. 1747-1754
-
-
Drach, J.1
Gsur, A.2
Hamilton, G.3
Zhao, S.4
Angerler, J.5
Fiegl, M.6
Zojer, N.7
-
6
-
-
0030916246
-
Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment
-
Fardel O, Lecureur V, Daval S, Corlu A, Guillouzo A (1997) Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment. Eur J Biochem 246:186-192
-
(1997)
Eur J Biochem
, vol.246
, pp. 186-192
-
-
Fardel, O.1
Lecureur, V.2
Daval, S.3
Corlu, A.4
Guillouzo, A.5
-
7
-
-
0033724658
-
The effect of rifampin treatment on intestinal expression of human MRP transporters
-
Fromm MF, Kauffmann HM, Fritz P, Burk O, Kroemer HK, Warzok RW, Eichelbaum M, et al. (2000) The effect of rifampin treatment on intestinal expression of human MRP transporters. Am J Pathol 157:1575-1580
-
(2000)
Am J Pathol
, vol.157
, pp. 1575-1580
-
-
Fromm, M.F.1
Kauffmann, H.M.2
Fritz, P.3
Burk, O.4
Kroemer, H.K.5
Warzok, R.W.6
Eichelbaum, M.7
-
8
-
-
0035805536
-
Nuclear receptor response elements mediate induction of intestinal mdr1 by rifampin
-
Geick A, Eichelbaum M, Burk O (2001) Nuclear receptor response elements mediate induction of intestinal mdr1 by rifampin. J Biol Chem 276:14581-14587
-
(2001)
J Biol Chem
, vol.276
, pp. 14581-14587
-
-
Geick, A.1
Eichelbaum, M.2
Burk, O.3
-
9
-
-
0025190477
-
Initial congestive heart failure, six to ten years after doxorubicin chemotherapy for childhood cancer
-
Goorin AM, Chauvenet AR, Perez-Atayde AR, Cruz J, McKone R, Lipshultz SE (1990) Initial congestive heart failure, six to ten years after doxorubicin chemotherapy for childhood cancer. J Pediatr 116:144-147
-
(1990)
J Pediatr
, vol.116
, pp. 144-147
-
-
Goorin, A.M.1
Chauvenet, A.R.2
Perez-Atayde, A.R.3
Cruz, J.4
McKone, R.5
Lipshultz, S.E.6
-
10
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B, Eichelbaum M, Fritz P, Kreichgauer HP, von Richter O, Zundler J, Kroemer HK (1999) The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J Clin Invest 104:147-153
-
(1999)
J Clin Invest
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
Von Richter, O.5
Zundler, J.6
Kroemer, H.K.7
-
11
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A, Cascorbi I, et al. (2000) Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 97:3473-3478
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmoller, J.5
Johne, A.6
Cascorbi, I.7
-
12
-
-
0027184425
-
High levels of P-glycoprotein detected in isolated brain capillaries
-
Jette L, Tetu B, Beliveau R (1993) High levels of P-glycoprotein detected in isolated brain capillaries. Biochim Biophys Acta 1150:147-154
-
(1993)
Biochim Biophys Acta
, vol.1150
, pp. 147-154
-
-
Jette, L.1
Tetu, B.2
Beliveau, R.3
-
13
-
-
0027146389
-
Transport of celiprolol across human intestinal epithelial (Caco-2) cells: Mediation of secretion by multiple transporters including P-glycoprotein
-
Karlsson J, Kuo SM, Ziemniak J, Artursson P (1993) Transport of celiprolol across human intestinal epithelial (Caco-2) cells: mediation of secretion by multiple transporters including P-glycoprotein. Br J Pharmacol 110:1009-1016
-
(1993)
Br J Pharmacol
, vol.110
, pp. 1009-1016
-
-
Karlsson, J.1
Kuo, S.M.2
Ziemniak, J.3
Artursson, P.4
-
14
-
-
0032705762
-
Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice
-
Kawahara M, Sakata A, Miyashita T, Tamai I, Tsuji A (1999) Physiologically based pharmacokinetics of digoxin in mdr1a knockout mice. J Pharmacol Sci 88:1281-1287
-
(1999)
J Pharmacol Sci
, vol.88
, pp. 1281-1287
-
-
Kawahara, M.1
Sakata, A.2
Miyashita, T.3
Tamai, I.4
Tsuji, A.5
-
15
-
-
0026031848
-
Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood
-
Lipshultz SE, Colan SD, Gelber RD, Perez-Atayde AR, Sallan SE, Sanders SP (1991) Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood. N Engl J Med 324:808-815
-
(1991)
N Engl J Med
, vol.324
, pp. 808-815
-
-
Lipshultz, S.E.1
Colan, S.D.2
Gelber, R.D.3
Perez-Atayde, A.R.4
Sallan, S.E.5
Sanders, S.P.6
-
16
-
-
0032217037
-
Agonistic anti-beta1-adrenergic receptor autoantibodies from cardiomyopathy patients reduce the beta1-adrenergic receptor expression in neonatal rat cardiomyocytes
-
Podlowski S, Luther HP, Morwinski R, Muller J, Wallukat G (1998) Agonistic anti-beta1-adrenergic receptor autoantibodies from cardiomyopathy patients reduce the beta1-adrenergic receptor expression in neonatal rat cardiomyocytes. Circulation 98:2470-2476
-
(1998)
Circulation
, vol.98
, pp. 2470-2476
-
-
Podlowski, S.1
Luther, H.P.2
Morwinski, R.3
Muller, J.4
Wallukat, G.5
-
17
-
-
0024538797
-
Prediction of doxorubicin resistance in vitro in myeloma, lymphoma, and breast cancer by P-glycoprotein staining
-
Salmon SE, Grogan TM, Miller T, Scheper R, Dalton WS (1989) Prediction of doxorubicin resistance in vitro in myeloma, lymphoma, and breast cancer by P-glycoprotein staining. J Natl Cancer Inst 81:696-701
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 696-701
-
-
Salmon, S.E.1
Grogan, T.M.2
Miller, T.3
Scheper, R.4
Dalton, W.S.5
-
18
-
-
0031158805
-
The physiological function of drug-transporting P-glycoproteins
-
Schinkel AH (1997) The physiological function of drug-transporting P-glycoproteins. Semin Cancer Biol 8:161-170
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
19
-
-
4243801613
-
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
-
Schinkel AH, Mayer U, Wagenaar E, Mol CA, van Deemter L, Smit JJ, van der Valk MA, et al. (1997) Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins. Proc Natl Acad Sci USA 94:4028-4033
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4028-4033
-
-
Schinkel, A.H.1
Mayer, U.2
Wagenaar, E.3
Mol, C.A.4
Van Deemter, L.5
Smit, J.J.6
Van der Valk, M.A.7
-
20
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel AH, Wagenaar E, Mol CA, van Deemter L (1996) P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 97:2517-2524
-
(1996)
J Clin Invest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
Van Deemter, L.4
-
21
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, Takahashi M, et al. (2001) Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exp Ther 297:1137-1143
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
Takahashi, M.7
-
22
-
-
0034681831
-
Gene expression in distinct regions of the heart
-
Thum T, Borlak J (2000) Gene expression in distinct regions of the heart. Lancet 355:979-983
-
(2000)
Lancet
, vol.355
, pp. 979-983
-
-
Thum, T.1
Borlak, J.2
-
23
-
-
0028895740
-
MDR1 gene expression in brain of patients with medically intractable epilepsy
-
Tishler DM, Weinberg KI, Hinton DR, Barbaro N, Annett GM, Raffel C (1995) MDR1 gene expression in brain of patients with medically intractable epilepsy. Epilepsia 36:1-6
-
(1995)
Epilepsia
, vol.36
, pp. 1-6
-
-
Tishler, D.M.1
Weinberg, K.I.2
Hinton, D.R.3
Barbaro, N.4
Annett, G.M.5
Raffel, C.6
-
24
-
-
0032889057
-
Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdrla P-glycoprotein
-
van Asperen J, van Tellingen O, Tijssen F, Schinkel AH, Beijnen JH (1999) Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdrla P-glycoprotein. Br J Cancer 79:108-113
-
(1999)
Br J Cancer
, vol.79
, pp. 108-113
-
-
Van Asperen, J.1
Van Tellingen, O.2
Tijssen, F.3
Schinkel, A.H.4
Beijnen, J.H.5
-
25
-
-
0013363878
-
Expression of P-glycoprotein in medically intractable epilepsy
-
Vogelgesang S, Schroeder E, Runge U, Gaab MR, Piek J, Cascorbi I, Siegmund W, et al. (2001) Expression of P-glycoprotein in medically intractable epilepsy. Acta Neuropathol (Berl) 102:545
-
(2001)
Acta Neuropathol (Berl)
, vol.102
, pp. 545
-
-
Vogelgesang, S.1
Schroeder, E.2
Runge, U.3
Gaab, M.R.4
Piek, J.5
Cascorbi, I.6
Siegmund, W.7
-
26
-
-
0033865280
-
Oral bioavailability of digoxin is enhanced by talinolol: Evidence for involvement of intestinal P-glycoprotein
-
Westphal K, Weinbrenner A, Giessmann T, Stuhr M, Franke G, Zschiesche M, Oertel R, et al. (2000) Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein. Clin Pharmacol Ther 68:6-12
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 6-12
-
-
Westphal, K.1
Weinbrenner, A.2
Giessmann, T.3
Stuhr, M.4
Franke, G.5
Zschiesche, M.6
Oertel, R.7
-
27
-
-
20244386956
-
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
-
Wijnholds J, Evers R, van Leusden MR, Mol CA, Zaman GJ, Mayer U, Beijnen JH, et al. (1997) Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nature Med 3:1275-1279
-
(1997)
Nature Med
, vol.3
, pp. 1275-1279
-
-
Wijnholds, J.1
Evers, R.2
Van Leusden, M.R.3
Mol, C.A.4
Zaman, G.J.5
Mayer, U.6
Beijnen, J.H.7
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