-
1
-
-
0023522193
-
Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene
-
Ueda K, Pastan I, Gottesman MM. Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene. J Biol Chem 1987; 262:17432-17436.
-
(1987)
J Biol Chem
, vol.262
, pp. 17432-17436
-
-
Ueda, K.1
Pastan, I.2
Gottesman, M.M.3
-
2
-
-
0025191307
-
Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins
-
Chen CJ, Clark D, Ueda K, Pastan I, Gottesman MM, Roninson IB. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins. J Biol Chem 1990; 265:506-514.
-
(1990)
J Biol Chem
, vol.265
, pp. 506-514
-
-
Chen, C.J.1
Clark, D.2
Ueda, K.3
Pastan, I.4
Gottesman, M.M.5
Roninson, I.B.6
-
4
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 1999; 39:361-398.
-
(1999)
Annu Rev Pharmacol Toxicol
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
5
-
-
0031158805
-
The physiological function of drug-transporting P-glycoproteins
-
Schinkel AH. The physiological function of drug-transporting P-glycoproteins. Semin Cancer Biol 1997;8:161-170.
-
(1997)
Semin Cancer Biol
, vol.8
, pp. 161-170
-
-
Schinkel, A.H.1
-
6
-
-
0033980182
-
P-glycoprotein: A defense mechanism limiting oral bioavailability and CNS accumulation of drugs
-
Fromm MF. P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs. Int J Clin Pharmacol Ther 2000; 38:69-74.
-
(2000)
Int J Clin Pharmacol Ther
, vol.38
, pp. 69-74
-
-
Fromm, M.F.1
-
7
-
-
0024362996
-
P-glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance
-
Kioka N, Tsubota J, Kakehi Y, Komano T, Gottesman MM, Pastan I, et al. P-glycoprotein gene (MDR1) cDNA from human adrenal: normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance. Biochem Biophys Res Comm 1989; 162:224-231.
-
(1989)
Biochem Biophys Res Comm
, vol.162
, pp. 224-231
-
-
Kioka, N.1
Tsubota, J.2
Kakehi, Y.3
Komano, T.4
Gottesman, M.M.5
Pastan, I.6
-
8
-
-
0032030654
-
Genetic polymorphism in MDR-1: A tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors
-
Mickley LA, Lee JS, Weng Z, Zhan Z, Alvarez M, Wilson W, et al. Genetic polymorphism in MDR-1: a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors. Blood 1998; 91:1749-1756.
-
(1998)
Blood
, vol.91
, pp. 1749-1756
-
-
Mickley, L.A.1
Lee, J.S.2
Weng, Z.3
Zhan, Z.4
Alvarez, M.5
Wilson, W.6
-
9
-
-
0034724324
-
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
-
Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmöller J, Johne A, et al. Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97:3473-3478.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3473-3478
-
-
Hoffmeyer, S.1
Burk, O.2
Von Richter, O.3
Arnold, H.P.4
Brockmöller, J.5
Johne, A.6
-
10
-
-
0034997034
-
Expression of P-glycoprotein in human placenta: Relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene
-
Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, et al. Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene. J Pharmacol Exper Ther 2001; 297:1137-1143.
-
(2001)
J Pharmacol Exper Ther
, vol.297
, pp. 1137-1143
-
-
Tanabe, M.1
Ieiri, I.2
Nagata, N.3
Inoue, K.4
Ito, S.5
Kanamori, Y.6
-
11
-
-
0035103009
-
Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
-
Ito S, Ieiri I, Tanabe M, Suzuki A, Higuchi S, Otsubo K. Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects. Pharmacogenetics 2001; 11:175-184.
-
(2001)
Pharmacogenetics
, vol.11
, pp. 175-184
-
-
Ito, S.1
Ieiri, I.2
Tanabe, M.3
Suzuki, A.4
Higuchi, S.5
Otsubo, K.6
-
12
-
-
0035104031
-
Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects
-
Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects. Clin Pharmacol Ther 2001; 69:169-174.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 169-174
-
-
Cascorbi, I.1
Gerloff, T.2
Johne, A.3
Meisel, C.4
Hoffmeyer, S.5
Schwab, M.6
-
13
-
-
3042772026
-
Identification of functionally variant MDR1 alleles among European Americans and African Americans
-
Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI, et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70:189-199.
-
(2001)
Clin Pharmacol Ther
, vol.70
, pp. 189-199
-
-
Kim, R.B.1
Leake, B.F.2
Choo, E.F.3
Dresser, G.K.4
Kubba, S.V.5
Schwarz, U.I.6
-
14
-
-
0036164594
-
Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population
-
Saito S, Iida A, Sekine A, Miura Y, Ogawa C, Kawauchi S, et al. Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population. J Hum Genet 2002; 47:38-50.
-
(2002)
J Hum Genet
, vol.47
, pp. 38-50
-
-
Saito, S.1
Iida, A.2
Sekine, A.3
Miura, Y.4
Ogawa, C.5
Kawauchi, S.6
-
15
-
-
0037022006
-
Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
-
Fellay J, Marzolini C, Meaden ER, Back DJ, Buclin T, Chave JP, et al. Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet 2002; 359:30-36.
-
(2002)
Lancet
, vol.359
, pp. 30-36
-
-
Fellay, J.1
Marzolini, C.2
Meaden, E.R.3
Back, D.J.4
Buclin, T.5
Chave, J.P.6
-
16
-
-
0034771497
-
MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects
-
Sakaeda T, Nakamura T, Horinouchi M, Kakumoto M, Ohmoto N, Sakai T, et al. MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects. Pharm Res 2001; 18:1400-1404.
-
(2001)
Pharm Res
, vol.18
, pp. 1400-1404
-
-
Sakaeda, T.1
Nakamura, T.2
Horinouchi, M.3
Kakumoto, M.4
Ohmoto, N.5
Sakai, T.6
-
17
-
-
0035999902
-
MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine
-
Drescher S, Schaeffeler E, Hitzl M, Hofmann U, Schwab M, Brinkmann U, et al. MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine. Br J Clin Pharmacol 2002; 53:526-534.
-
(2002)
Br J Clin Pharmacol
, vol.53
, pp. 526-534
-
-
Drescher, S.1
Schaeffeler, E.2
Hitzl, M.3
Hofmann, U.4
Schwab, M.5
Brinkmann, U.6
-
18
-
-
0036281948
-
Influence of functional MDR1 gene polymorphisms on P-glycoprotein activity in CD34+ hematopoietic stem cells
-
Calado RT, Falcao RP, Garcia AB, Gabellini SM, Zago MA, Franco RF. Influence of functional MDR1 gene polymorphisms on P-glycoprotein activity in CD34+ hematopoietic stem cells. Haematologica 2002; 87:564-568.
-
(2002)
Haematologica
, vol.87
, pp. 564-568
-
-
Calado, R.T.1
Falcao, R.P.2
Garcia, A.B.3
Gabellini, S.M.4
Zago, M.A.5
Franco, R.F.6
-
19
-
-
0036667956
-
Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
-
Tang K, Ngoi SM, Gwee PC, Chua JM, Lee EJ, Chong SS, et al. Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics 2002; 12:437-450.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 437-450
-
-
Tang, K.1
Ngoi, S.M.2
Gwee, P.C.3
Chua, J.M.4
Lee, E.J.5
Chong, S.S.6
-
20
-
-
0036731995
-
MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients
-
Illmer T, Schuler US, Thiede C, Schwarz UI, Kim RB, Gotthard S, et al. MDR1 gene polymorphisms affect therapy outcome in acute myeloid leukemia patients. Cancer Res 2002; 62:4955-4962.
-
(2002)
Cancer Res
, vol.62
, pp. 4955-4962
-
-
Illmer, T.1
Schuler, U.S.2
Thiede, C.3
Schwarz, U.I.4
Kim, R.B.5
Gotthard, S.6
-
21
-
-
0038612980
-
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints
-
Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, De La Cruz M, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A 2003; 100:5896-5901.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5896-5901
-
-
Leabman, M.K.1
Huang, C.C.2
DeYoung, J.3
Carlson, E.J.4
Taylor, T.R.5
De La Cruz, M.6
-
22
-
-
0024313579
-
Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
-
Tajima F. Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 1989; 123:585-595.
-
(1989)
Genetics
, vol.123
, pp. 585-595
-
-
Tajima, F.1
-
23
-
-
0001771498
-
Evolution in Mendelian populations
-
Wright S. Evolution in Mendelian populations. Genetics 1931; 16:97-159.
-
(1931)
Genetics
, vol.16
, pp. 97-159
-
-
Wright, S.1
-
24
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
Stephens M, Smith NJ, Donnelly P. A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 2001; 68:978-989.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
-
25
-
-
0029149631
-
Mitochondrial portraits of human populations using median networks
-
Bandelt HJ, Forster P, Sykes BC, Richards MB. Mitochondrial portraits of human populations using median networks. Genetics 1995; 141:743-753.
-
(1995)
Genetics
, vol.141
, pp. 743-753
-
-
Bandelt, H.J.1
Forster, P.2
Sykes, B.C.3
Richards, M.B.4
-
26
-
-
0032972599
-
DnaSP version 3: An integrated program for molecular population genetics and molecular evolution analysis
-
Rozas J, Rozas R. DnaSP version 3: an integrated program for molecular population genetics and molecular evolution analysis. Bioinformatics 1999; 15:174-175.
-
(1999)
Bioinformatics
, vol.15
, pp. 174-175
-
-
Rozas, J.1
Rozas, R.2
-
28
-
-
0023339852
-
A test of neutral molecular evolution based on nucleotide data
-
Hudson RR, Kreitman M, Aguade M. A test of neutral molecular evolution based on nucleotide data. Genetics 1987; 116:153-159.
-
(1987)
Genetics
, vol.116
, pp. 153-159
-
-
Hudson, R.R.1
Kreitman, M.2
Aguade, M.3
-
29
-
-
0343306779
-
Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein
-
Essodaigui M, Broxterman HJ, Garnier-Suillerot A. Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein. Biochemistry 1998; 37:2243-2250.
-
(1998)
Biochemistry
, vol.37
, pp. 2243-2250
-
-
Essodaigui, M.1
Broxterman, H.J.2
Garnier-Suillerot, A.3
-
30
-
-
0032991552
-
Characterization of single-nucleotide polymorphisms in coding regions of human genes
-
Cargill M, Altshuler D, Ireland J, Sklar P, Ardlie K, Patil N, et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 1999; 22:231-238.
-
(1999)
Nat Genet
, vol.22
, pp. 231-238
-
-
Cargill, M.1
Altshuler, D.2
Ireland, J.3
Sklar, P.4
Ardlie, K.5
Patil, N.6
-
31
-
-
0032990407
-
Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis
-
Halushka MK, Fan JB, Bentley K, Hsie L, Shen N, Weder A, et al. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet 1999; 22:239-247.
-
(1999)
Nat Genet
, vol.22
, pp. 239-247
-
-
Halushka, M.K.1
Fan, J.B.2
Bentley, K.3
Hsie, L.4
Shen, N.5
Weder, A.6
-
32
-
-
0033787023
-
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene
-
Nickerson DA, Taylor SL, Fullerton SM, Weiss KM, Clark AG, Stengard JH, et al. Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene. Genome Res 2000; 10:1532-1545.
-
(2000)
Genome Res
, vol.10
, pp. 1532-1545
-
-
Nickerson, D.A.1
Taylor, S.L.2
Fullerton, S.M.3
Weiss, K.M.4
Clark, A.G.5
Stengard, J.H.6
-
33
-
-
0035919656
-
Haplotype variation and linkage disequilibrium in 313 human genes
-
Stephens JC, Schneider JA, Tanguay DA, Choi J, Acharya T, Stanley SE, et al. Haplotype variation and linkage disequilibrium in 313 human genes. Science 2001; 293:489-493.
-
(2001)
Science
, vol.293
, pp. 489-493
-
-
Stephens, J.C.1
Schneider, J.A.2
Tanguay, D.A.3
Choi, J.4
Acharya, T.5
Stanley, S.E.6
-
34
-
-
0036664926
-
Sequence polymorphism at the human apolipoprotein AII gene (APOA2): Unexpected deficit of variation in an African-American sample
-
Fullerton SM, Clark AG, Weiss KM, Taylor SL, Stengard JH, Salomaa V, et al. Sequence polymorphism at the human apolipoprotein AII gene (APOA2): unexpected deficit of variation in an African-American sample. Hum Genet 2002; 111:75-87.
-
(2002)
Hum Genet
, vol.111
, pp. 75-87
-
-
Fullerton, S.M.1
Clark, A.G.2
Weiss, K.M.3
Taylor, S.L.4
Stengard, J.H.5
Salomaa, V.6
-
35
-
-
0036020986
-
Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function
-
Leabman MK, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, et al. Polymorphisms in a human kidney xenobiotic transporter, OCT2, exhibit altered function. Pharmacogenetics 2002; 12:395-405.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 395-405
-
-
Leabman, M.K.1
Huang, C.C.2
Kawamoto, M.3
Johns, S.J.4
Stryke, D.5
Ferrin, T.E.6
-
36
-
-
0032231888
-
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
-
Clark AG, Weiss KM, Nickerson DA, Taylor SL, Buchanan A, Stengård J, et al. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet 1998; 63:595-612.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 595-612
-
-
Clark, A.G.1
Weiss, K.M.2
Nickerson, D.A.3
Taylor, S.L.4
Buchanan, A.5
Stengård, J.6
-
37
-
-
0034081306
-
Suggestions for the nomenclature of human alleles: Relevance to ecogenetics, pharmacogenetics and molecular epidemiology
-
Nebert DW. Suggestions for the nomenclature of human alleles: relevance to ecogenetics, pharmacogenetics and molecular epidemiology. Pharmacogenetics 2000; 10:279-290.
-
(2000)
Pharmacogenetics
, vol.10
, pp. 279-290
-
-
Nebert, D.W.1
-
38
-
-
0022211482
-
Statistical properties of the number of recombination events in the history of a sample of DNA sequences
-
Hudson RR, Kaplan NL. Statistical properties of the number of recombination events in the history of a sample of DNA sequences. Genetics 1985; 111:147-164.
-
(1985)
Genetics
, vol.111
, pp. 147-164
-
-
Hudson, R.R.1
Kaplan, N.L.2
-
39
-
-
0037147189
-
Genetic structure of human populations
-
Rosenberg NA, Pritchard JK, Weber JL, Cann HM, Kidd KK, Zhivotovsky LA, et al. Genetic structure of human populations. Science 2002; 298:2381-2385.
-
(2002)
Science
, vol.298
, pp. 2381-2385
-
-
Rosenberg, N.A.1
Pritchard, J.K.2
Weber, J.L.3
Cann, H.M.4
Kidd, K.K.5
Zhivotovsky, L.A.6
-
40
-
-
0030946551
-
Ethnic-affiliation estimation by use of population-specific DNA markers
-
Shriver MD, Smith MW, Jin L, Marcini A, Akey JM, Deka R, et al. Ethnic-affiliation estimation by use of population-specific DNA markers. Am J Hum Genet 1997; 60:957-964.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 957-964
-
-
Shriver, M.D.1
Smith, M.W.2
Jin, L.3
Marcini, A.4
Akey, J.M.5
Deka, R.6
-
41
-
-
0032472024
-
Estimating African American admixture proportions by use of population-specific alleles
-
Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, Cooper R, et al. Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet 1998; 63:1839-1851.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 1839-1851
-
-
Parra, E.J.1
Marcini, A.2
Akey, J.3
Martinson, J.4
Batzer, M.A.5
Cooper, R.6
-
42
-
-
0041691044
-
Minimal haplotype tagging
-
in press
-
P Sebastiani, R Lazarus, ST Weiss, LM Kunkel, IS Kohane, MF Ramoni. Minimal haplotype tagging. Proc Nat Acad Sci USA 2003; in press.
-
(2003)
Proc Nat Acad Sci USA
-
-
Sebastiani, P.1
Lazarus, R.2
Weiss, S.T.3
Kunkel, L.M.4
Kohane, I.S.5
Ramoni, M.F.6
-
43
-
-
0036082545
-
Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system
-
Kimchi-Sarfaty C, Gribar JJ, Gottesman MM. Functional characterization of coding polymorphisms in the human MDR1 gene using a vaccinia virus expression system. Mol Pharmacol 2002; 62:1-6.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 1-6
-
-
Kimchi-Sarfaty, C.1
Gribar, J.J.2
Gottesman, M.M.3
-
44
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel AH, Smit JJ, van Tellingen O, Beijnen JH, Wagenaar E, van Deemter L, et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 1994; 77:491-502.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
-
45
-
-
0028825399
-
Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
-
Schinkel AH, Wagenaar E, van Deemter L, Mol CA, Borst P. Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. J Clin Invest 1995; 96:1698-1705.
-
(1995)
J Clin Invest
, vol.96
, pp. 1698-1705
-
-
Schinkel, A.H.1
Wagenaar, E.2
Van Deemter, L.3
Mol, C.A.4
Borst, P.5
-
46
-
-
0029892497
-
P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
-
Schinkel AH, Wagenaar E, Mol CA, van Deemter L. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 1996; 97:2517-2524.
-
(1996)
J Clin Invest
, vol.97
, pp. 2517-2524
-
-
Schinkel, A.H.1
Wagenaar, E.2
Mol, C.A.3
Van Deemter, L.4
-
47
-
-
0029860174
-
Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein
-
Mayer U, Wagenaar E, Beijnen JH, Smit JW, Meijer DK, van Asperen J, et al. Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein. Br J Pharmacol 1996; 119:1038-1044.
-
(1996)
Br J Pharmacol
, vol.119
, pp. 1038-1044
-
-
Mayer, U.1
Wagenaar, E.2
Beijnen, J.H.3
Smit, J.W.4
Meijer, D.K.5
Van Asperen, J.6
-
48
-
-
0033514320
-
Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine
-
Fromm MF, Kim RB, Stein CM, Wilkinson GR, Roden DM. Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine. Circulation 1999; 99:552-557.
-
(1999)
Circulation
, vol.99
, pp. 552-557
-
-
Fromm, M.F.1
Kim, R.B.2
Stein, C.M.3
Wilkinson, G.R.4
Roden, D.M.5
-
49
-
-
0034016617
-
Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein
-
Thompson SJ, Koszdin K, Bernards CM. Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein. Anesthesiology 2000; 92:1392-1399.
-
(2000)
Anesthesiology
, vol.92
, pp. 1392-1399
-
-
Thompson, S.J.1
Koszdin, K.2
Bernards, C.M.3
-
50
-
-
0035206438
-
P-glycoprotein expression in adult acute myeloid leukemia: Correlation with induction treatment outcome
-
Tothova E, Elbertova A, Fricova M, Kafkova A, Hlebaskova M, Svorcova E, et al. P-glycoprotein expression in adult acute myeloid leukemia: correlation with induction treatment outcome. Neoplasma 2001; 48:393-397.
-
(2001)
Neoplasma
, vol.48
, pp. 393-397
-
-
Tothova, E.1
Elbertova, A.2
Fricova, M.3
Kafkova, A.4
Hlebaskova, M.5
Svorcova, E.6
-
51
-
-
0036533566
-
Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin
-
Tada Y, Wada M, Migita T, Nagayama J, Hinoshita E, Mochida Y, et al. Increased expression of multidrug resistance-associated proteins in bladder cancer during clinical course and drug resistance to doxorubicin. Int J Cancer 2002; 98:630-635.
-
(2002)
Int J Cancer
, vol.98
, pp. 630-635
-
-
Tada, Y.1
Wada, M.2
Migita, T.3
Nagayama, J.4
Hinoshita, E.5
Mochida, Y.6
-
52
-
-
0036903656
-
Relationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression
-
Hsia TC, Lin CC, Wang JJ, Ho ST, Kao A. Relationship between chemotherapy response of small cell lung cancer and P-glycoprotein or multidrug resistance-related protein expression. Lung 2002; 180:173-179.
-
(2002)
Lung
, vol.180
, pp. 173-179
-
-
Hsia, T.C.1
Lin, C.C.2
Wang, J.J.3
Ho, S.T.4
Kao, A.5
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