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Volumn 9, Issue 1, 2008, Pages 19-33

Global analysis of genetic variation in SLCO1B1

Author keywords

Genetic variation; OATP1B1; Organic anion transporting polypeptide; Pharmacogenetics; Polymorphism; SLCO1B1

Indexed keywords

ORGANIC ANION TRANSPORTER 2; DNA; ORGANIC ANION TRANSPORTER; SLCO1B1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

EID: 40949126593     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.9.1.19     Document Type: Article
Times cited : (176)

References (45)
  • 1
    • 0035971239 scopus 로고    scopus 로고
    • Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6
    • Cui Y, König J, Leier I, Buchholz U, Keppler D. Hepatic uptake of bilirubin and its conjugates by the human organic anion transporter SLC21A6. J. Biol. Chem. 276(13), 9626-9630 (2001).
    • (2001) J. Biol. Chem , vol.276 , Issue.13 , pp. 9626-9630
    • Cui, Y.1    König, J.2    Leier, I.3    Buchholz, U.4    Keppler, D.5
  • 2
    • 24344439264 scopus 로고    scopus 로고
    • Transporters and drug therapy: Implications for drug disposition and disease
    • Ho RH, Kim RB: Transporters and drug therapy: implications for drug disposition and disease. Clin. Pharmacol. Ther. 78(3), 260-277 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , Issue.3 , pp. 260-277
    • Ho, R.H.1    Kim, R.B.2
  • 3
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    • Hsiang B, Zhu Y, Wang Z et al.: A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J. Biol. Chem. 274(52), 37161-37168 (1999).
    • (1999) J. Biol. Chem , vol.274 , Issue.52 , pp. 37161-37168
    • Hsiang, B.1    Zhu, Y.2    Wang, Z.3
  • 4
    • 0040368659 scopus 로고    scopus 로고
    • Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1
    • Abe T, Kakyo M, Tokui T et al.: Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J. Biol. Chem. 274(24), 17159-17163 (1999).
    • (1999) J. Biol. Chem , vol.274 , Issue.24 , pp. 17159-17163
    • Abe, T.1    Kakyo, M.2    Tokui, T.3
  • 5
    • 0035929574 scopus 로고    scopus 로고
    • Polymorphisms in OATP-C: Identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
    • Tirona RG, Leake BF, Merino G, Kim RB: Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J. Biol. Chem. 276(38), 35669-35675 (2001).
    • (2001) J. Biol. Chem , vol.276 , Issue.38 , pp. 35669-35675
    • Tirona, R.G.1    Leake, B.F.2    Merino, G.3    Kim, R.B.4
  • 6
    • 0034709561 scopus 로고    scopus 로고
    • Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family
    • Tamai I, Nezu J, Uchino H et al.: Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem. Biophys. Res. Commun. 273(1), 251-260 (2000).
    • (2000) Biochem. Biophys. Res. Commun , vol.273 , Issue.1 , pp. 251-260
    • Tamai, I.1    Nezu, J.2    Uchino, H.3
  • 7
    • 33745248116 scopus 로고    scopus 로고
    • Vectorial transport of enalapril by OATP1A1/MRP2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers
    • Liu L, Cui Y, Chung AY et al.: Vectorial transport of enalapril by OATP1A1/MRP2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers. J. Pharmacol. Exp. Ther. 318(1), 395-402 (2006).
    • (2006) J. Pharmacol. Exp. Ther , vol.318 , Issue.1 , pp. 395-402
    • Liu, L.1    Cui, Y.2    Chung, A.Y.3
  • 8
    • 33646205286 scopus 로고    scopus 로고
    • Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril
    • Maeda K, Ieiri I, Yasuda K et al.: Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril. Clin. Pharmacol. Ther. 79(5), 427-439 (2006).
    • (2006) Clin. Pharmacol. Ther , vol.79 , Issue.5 , pp. 427-439
    • Maeda, K.1    Ieiri, I.2    Yasuda, K.3
  • 9
    • 14044260589 scopus 로고    scopus 로고
    • Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10 -hydroxycamptothecin: In vitro evidence and effect of single nucleotide polymorphisms
    • Nozawa T, Minami H, Sugiura S, Tsuji A, Tamai I: Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10 -hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. Drug Metab. Dispos. 33(3), 434-439 (2005).
    • (2005) Drug Metab. Dispos , vol.33 , Issue.3 , pp. 434-439
    • Nozawa, T.1    Minami, H.2    Sugiura, S.3    Tsuji, A.4    Tamai, I.5
  • 10
    • 33645816996 scopus 로고    scopus 로고
    • OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker
    • Nakagomi-Hagihara R, Nakai D, Kawai K et al.: OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker. Drug Metab. Dispos. 34(5), 862-869 (2006).
    • (2006) Drug Metab. Dispos , vol.34 , Issue.5 , pp. 862-869
    • Nakagomi-Hagihara, R.1    Nakai, D.2    Kawai, K.3
  • 11
    • 33745231761 scopus 로고    scopus 로고
    • Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans
    • Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z, Sugiyama Y: Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans. Drug Metab. Dispos. 34(7), 1247-1254 (2006).
    • (2006) Drug Metab. Dispos , vol.34 , Issue.7 , pp. 1247-1254
    • Yamashiro, W.1    Maeda, K.2    Hirouchi, M.3    Adachi, Y.4    Hu, Z.5    Sugiyama, Y.6
  • 12
    • 3242808852 scopus 로고    scopus 로고
    • High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)
    • Niemi M, Schaeffeler E, Lang T et al.: High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1). Pharmacogenetics 14(7), 429-440 (2004).
    • (2004) Pharmacogenetics , vol.14 , Issue.7 , pp. 429-440
    • Niemi, M.1    Schaeffeler, E.2    Lang, T.3
  • 13
    • 34548103493 scopus 로고    scopus 로고
    • Role of OATP transporters in the disposition of drugs
    • Niemi M: Role of OATP transporters in the disposition of drugs. Pharmacogenomics 8(7), 787-802 (2007).
    • (2007) Pharmacogenomics , vol.8 , Issue.7 , pp. 787-802
    • Niemi, M.1
  • 14
    • 22544454498 scopus 로고    scopus 로고
    • Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells
    • Kameyama Y, Yamashita K, Kobayashi K, Hosokawa M, Chiba K: Functional characterization of SLCO1B1 (OATP-C) variants, SLCO1B1*5, SLCO1B1*15 and SLCO1B1*15+C1007G, by using transient expression systems of HeLa and HEK293 cells. Pharmacogenet. Genomics 15(7), 513-522 (2005).
    • (2005) Pharmacogenet. Genomics , vol.15 , Issue.7 , pp. 513-522
    • Kameyama, Y.1    Yamashita, K.2    Kobayashi, K.3    Hosokawa, M.4    Chiba, K.5
  • 15
    • 0037216648 scopus 로고    scopus 로고
    • Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation
    • Tirona RG, Leake BF, Wolkoff AW, Kim RB: Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation. J. Pharmacol. Exp. Ther. 304(1), 223-228 (2003).
    • (2003) J. Pharmacol. Exp. Ther , vol.304 , Issue.1 , pp. 223-228
    • Tirona, R.G.1    Leake, B.F.2    Wolkoff, A.W.3    Kim, R.B.4
  • 16
    • 9244254743 scopus 로고    scopus 로고
    • Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C)
    • Iwai M, Suzuki H, Ieiri I, Otsubo K, Sugiyama Y: Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C). Pharmacogenetics 14(11), 749-757 (2004).
    • (2004) Pharmacogenetics , vol.14 , Issue.11 , pp. 749-757
    • Iwai, M.1    Suzuki, H.2    Ieiri, I.3    Otsubo, K.4    Sugiyama, Y.5
  • 17
    • 33751096467 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid
    • Pasanen MK, Neuvonen M, Neuvonen PJ, Niemi M: SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid. Pharmacogenet. Genomics 16(12), 873-879 (2006).
    • (2006) Pharmacogenet. Genomics , vol.16 , Issue.12 , pp. 873-879
    • Pasanen, M.K.1    Neuvonen, M.2    Neuvonen, P.J.3    Niemi, M.4
  • 18
    • 33749049136 scopus 로고    scopus 로고
    • SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin
    • Niemi M, Pasanen MK, Neuvonen PJ: SLCO1B1 polymorphism and sex affect the pharmacokinetics of pravastatin but not fluvastatin. Clin. Pharmacol. Ther. 80(4), 356-366 (2006).
    • (2006) Clin. Pharmacol. Ther , vol.80 , Issue.4 , pp. 356-366
    • Niemi, M.1    Pasanen, M.K.2    Neuvonen, P.J.3
  • 19
    • 36148953896 scopus 로고    scopus 로고
    • Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin
    • Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M: Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Clin. Pharmacol. Ther. 82(6), 726-733 (2007).
    • (2007) Clin. Pharmacol. Ther , vol.82 , Issue.6 , pp. 726-733
    • Pasanen, M.K.1    Fredrikson, H.2    Neuvonen, P.J.3    Niemi, M.4
  • 20
    • 18244386206 scopus 로고    scopus 로고
    • Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1)
    • Niemi M, Kivistö KT, Hofmann U, Schwab M. Eichelbaum M, Fromm MF: Fexofenadine pharmacokinetics are associated with a polymorphism of the SLCO1B1 gene (encoding OATP1B1). Br J. Clin. Pharmacol. 59(5). 602-604 (2005).
    • (2005) Br J. Clin. Pharmacol , vol.59 , Issue.5 , pp. 602-604
    • Niemi, M.1    Kivistö, K.T.2    Hofmann, U.3    Schwab, M.4    Eichelbaum, M.5    Fromm, M.F.6
  • 21
    • 20444466590 scopus 로고    scopus 로고
    • Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics
    • Niemi M, Backman JT, Kajosaari LI et al.: Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics. Clin. Pharmacol. Ther. 77(6), 468-478 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.77 , Issue.6 , pp. 468-478
    • Niemi, M.1    Backman, J.T.2    Kajosaari, L.I.3
  • 22
    • 0036073404 scopus 로고    scopus 로고
    • Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B ( SLC21A9): Allele frequencies in the Japanese population and functional analysis
    • Nozawa T, Nakajima M, Tamai I et al.: Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B ( SLC21A9): allele frequencies in the Japanese population and functional analysis. J. Pharmacol. Exp. Ther. 302 (2), 804-813 (2002).
    • (2002) J. Pharmacol. Exp. Ther , vol.302 , Issue.2 , pp. 804-813
    • Nozawa, T.1    Nakajima, M.2    Tamai, I.3
  • 23
    • 33745031039 scopus 로고    scopus 로고
    • Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population
    • Pasanen MK, Backman JT, Neuvonen PJ, Niemi M: Frequencies of single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide 1B1 SLCO1B1 gene in a Finnish population. Eur. J. Clin. Pharmacol. 62 (6), 409-415 (2006).
    • (2006) Eur. J. Clin. Pharmacol , vol.62 , Issue.6 , pp. 409-415
    • Pasanen, M.K.1    Backman, J.T.2    Neuvonen, P.J.3    Niemi, M.4
  • 24
    • 25844458977 scopus 로고    scopus 로고
    • Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment
    • Lee E, Ryan S, Birmingham B et al.: Rosuvastatin pharmacokinetics and pharmacogenetics in white and Asian subjects residing in the same environment. Clin. Pharmacol. Ther. 78(4), 330-341 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , Issue.4 , pp. 330-341
    • Lee, E.1    Ryan, S.2    Birmingham, B.3
  • 25
    • 34247627982 scopus 로고    scopus 로고
    • Pharmacogenetics of SLCO1B1: Haplotypes, htSNPs and hepatic expression in three distinct Asian populations
    • Jada SR, Xiaochen S, Yan LY et al.: Pharmacogenetics of SLCO1B1: haplotypes, htSNPs and hepatic expression in three distinct Asian populations. Eur J. Clin. Pharmacol. 63(6), 555-563 (2007).
    • (2007) Eur J. Clin. Pharmacol , vol.63 , Issue.6 , pp. 555-563
    • Jada, S.R.1    Xiaochen, S.2    Yan, L.Y.3
  • 26
    • 0038209381 scopus 로고    scopus 로고
    • Polymorphisms of OATP-C ( SLC21A6) and OAT3 (SLC22A8) genes: Consequences for pravastatin pharmacokinetics
    • Nishizato Y, Ieiri I, Suzuki H et al.: Polymorphisms of OATP-C ( SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics. Clin. Pharmacol, Ther. 73(6), 554-565 (2003).
    • (2003) Clin. Pharmacol, Ther , vol.73 , Issue.6 , pp. 554-565
    • Nishizato, Y.1    Ieiri, I.2    Suzuki, H.3
  • 27
    • 2042469487 scopus 로고    scopus 로고
    • Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics
    • Mwinyi J, Johne A. Bauer S, Roots I, Gerloff T: Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. Clin. Pharmacol. Ther. 75(5), 415-421 (2004).
    • (2004) Clin. Pharmacol. Ther , vol.75 , Issue.5 , pp. 415-421
    • Mwinyi, J.1    Johne, A.2    Bauer, S.3    Roots, I.4    Gerloff, T.5
  • 29
    • 25844440854 scopus 로고    scopus 로고
    • Ethnic differences in statin disposition
    • Tirona RG: Ethnic differences in statin disposition. Clin. Pharmacol. Ther. 78(4), 311-316 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , Issue.4 , pp. 311-316
    • Tirona, R.G.1
  • 30
    • 34447335619 scopus 로고    scopus 로고
    • Effect of drug transporter genotypes on pravastatin disposition in European- and African - American participants
    • Ho RH, Choi L, Lee W et al.: Effect of drug transporter genotypes on pravastatin disposition in European- and African - American participants. Pharmacogenet. Genomics 17(8), 647-656 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , Issue.8 , pp. 647-656
    • Ho, R.H.1    Choi, L.2    Lee, W.3
  • 31
    • 0037066430 scopus 로고    scopus 로고
    • A human genome diversity cell line panel
    • Cann HM, de Toma C, Cazes L et al.: A human genome diversity cell line panel. Science 296(5566), 261-262 (2002).
    • (2002) Science , vol.296 , Issue.5566 , pp. 261-262
    • Cann, H.M.1    de Toma, C.2    Cazes, L.3
  • 32
    • 27644509150 scopus 로고    scopus 로고
    • Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa
    • Ramachandran S, Deshpande O, Roseman CC et al.: Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa. Proc. Natl Acad. Sci. USA 102(44), 15942-15947 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.44 , pp. 15942-15947
    • Ramachandran, S.1    Deshpande, O.2    Roseman, C.C.3
  • 33
    • 0037147189 scopus 로고    scopus 로고
    • Genetic structure of human populations
    • Rósenberg NA, Pritchard JK, Weber JL et al.: Genetic structure of human populations. Science 298(5602), 2381-2385 (2002).
    • (2002) Science , vol.298 , Issue.5602 , pp. 2381-2385
    • Rósenberg, N.A.1    Pritchard, J.K.2    Weber, J.L.3
  • 34
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens M, Smith NJ, Donnelly P: A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68(4), 978-989 (2001).
    • (2001) Am. J. Hum. Genet , vol.68 , Issue.4 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 35
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of bayesian methods for haplotype reconstruction from population genotype data
    • Stephens M, Donnelly P: A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am. J. Hum. Genet. 73(5), 1162-1169 (2003).
    • (2003) Am. J. Hum. Genet , vol.73 , Issue.5 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 36
    • 0026681074 scopus 로고
    • Analysis of molecular variance inferred from metric distances among DNA haplotypes: Application to human mitochondrial DNA restriction data
    • Excoffier L, Smouse PE, Quattro JM: Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data. Genetics 131(2), 479-491 (1992).
    • (1992) Genetics , vol.131 , Issue.2 , pp. 479-491
    • Excoffier, L.1    Smouse, P.E.2    Quattro, J.M.3
  • 37
    • 33847031732 scopus 로고    scopus 로고
    • CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure
    • Sistonen J, Sajantila A, Lao O, Corander J, Barbujani G, Fuselli S: CYP2D6 worldwide genetic variation shows high frequency of altered activity variants and no continental structure. Pharmacogenet. Genomics 17(2), 93-101 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , Issue.2 , pp. 93-101
    • Sistonen, J.1    Sajantila, A.2    Lao, O.3    Corander, J.4    Barbujani, G.5    Fuselli, S.6
  • 38
    • 0036226789 scopus 로고    scopus 로고
    • Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms
    • Romualdi C, Balding D, Nasidze IS et al.: Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms. Genome Res. 12 (4), 602-612 (2002).
    • (2002) Genome Res , vol.12 , Issue.4 , pp. 602-612
    • Romualdi, C.1    Balding, D.2    Nasidze, I.S.3
  • 40
    • 0033912515 scopus 로고    scopus 로고
    • The distribution of human genetic diversity: A comparison of mitochondrial, autosomal. and Y-chromosome data
    • Jorde LB, Watkins WS, Barnshad MJ et al.: The distribution of human genetic diversity: a comparison of mitochondrial, autosomal. and Y-chromosome data. Am. J. Hum. Genet. 66(3), 979-988 (2000).
    • (2000) Am. J. Hum. Genet , vol.66 , Issue.3 , pp. 979-988
    • Jorde, L.B.1    Watkins, W.S.2    Barnshad, M.J.3
  • 41
    • 25844530136 scopus 로고    scopus 로고
    • Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers
    • Chung JY, Cho JY, Yu KS et al.: Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers. Clin. Pharmacol. Ther. 78(4), 342-350 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.78 , Issue.4 , pp. 342-350
    • Chung, J.Y.1    Cho, J.Y.2    Yu, K.S.3
  • 42
    • 33645876499 scopus 로고    scopus 로고
    • Influence of the SLCO1B1 *1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels
    • Gerloff T, Schaefer M, Mwinyi J et al.: Influence of the SLCO1B1 *1b and *5 haplotypes on pravastatin's cholesterol lowering capabilities and basal sterol serum levels. Naunyn Schmiedebergs Arch. Pharmacol. 373(1), 45-50 (2006).
    • (2006) Naunyn Schmiedebergs Arch. Pharmacol , vol.373 , Issue.1 , pp. 45-50
    • Gerloff, T.1    Schaefer, M.2    Mwinyi, J.3
  • 43
    • 33845420011 scopus 로고    scopus 로고
    • Drug interactions with lipid-lowering drugs: Mechanisms and clinical relevance
    • Neuvonen PJ, Niemi M, Backman JT. Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. Clin. Pharmacol. Ther. 80(6), 565-581 (2006).
    • (2006) Clin. Pharmacol. Ther , vol.80 , Issue.6 , pp. 565-581
    • Neuvonen, P.J.1    Niemi, M.2    Backman, J.T.3
  • 44
    • 18744388590 scopus 로고    scopus 로고
    • Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17
    • Niemi M, Neuvonen PJ, Hofmann U et al.: Acute effects of pravastatin on cholesterol synthesis are associated with SLCO1B1 (encoding OATP1B1) haplotype *17. Pharmacogenet. Genomics 15(5), 303-309 (2005).
    • (2005) Pharmacogenet. Genomics , vol.15 , Issue.5 , pp. 303-309
    • Niemi, M.1    Neuvonen, P.J.2    Hofmann, U.3
  • 45
    • 18844409084 scopus 로고    scopus 로고
    • OATP-C(OATP1B1)*15 is associated with statin induced myopathy in hypercholesterolemic patients
    • P
    • Morimoto K, Ueda S, Seki N et al.: OATP-C(OATP1B1)*15 is associated with statin induced myopathy in hypercholesterolemic patients. Clin. Pharmacol. Ther. 77 (2), P21 (2005).
    • (2005) Clin. Pharmacol. Ther , vol.77 , Issue.2 , pp. 21
    • Morimoto, K.1    Ueda, S.2    Seki, N.3


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