Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: An association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28

Drug Metabolism and Disposition

Volumn 30, Issue 4, 2002, Pages 363-364

  Itoda, Masaya ^a   Saito, Yoshiro ^a   Soyama, Akiko ^a   Saeki, Mayumi ^a   Murayama, Norie ^a   Ishida, Seiichi ^a   Sai, Kimie ^a   Nagano, Michiyo ^a   Suzuki, Hiroshi ^b   Sugiyama, Yuichi ^a,b   Ozawa, Shogo ^a   Sawada, Jun Ichi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; MULTIDRUG RESISTANCE PROTEIN 2;

ANION TRANSPORT; ARTICLE; DNA SEQUENCE; DRUG METABOLISM; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; JAPAN; MULTIDRUG RESISTANCE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION;

5' UNTRANSLATED REGIONS; AMINO ACID SUBSTITUTION; ASIAN CONTINENTAL ANCESTRY GROUP; CELL LINE; EXONS; GENOMIC LIBRARY; HUMANS; JAPAN; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 0036206860     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.4.363     Document Type: Article

References (9)

1. Biliary excretion mechanism of CPT-II and its metabolites in humans: Involvement of primary active transporters
2. Polymorphism of the transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
3. Expression of localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver
4. Multidrug resistance mediated by multidrug resistance protein (MRP) gene
5. Biology of multidrug resistance-associated protein, MRP
6. Apparent low frequency of sequence variability within the proximal promoter region of the cytochrome P450(CYP)3A5 gene in established cell lines from Japanese individuals
7. Identification of basic residues involved in drug export function of human multidrug resistance-associated protein 2
8. Excretion of GSSG and glutathione conjugates mediated by MRP1 and cMOAT/MRP2
9. Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome