메뉴 건너뛰기




Volumn 14, Issue 14, 2005, Pages 2075-2087

A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GUANINE; MULTIDRUG RESISTANCE PROTEIN 1; XENOBIOTIC AGENT;

EID: 26444438734     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi212     Document Type: Article
Times cited : (53)

References (44)
  • 1
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman, M.M., Fojo, T. and Bates, S.E. (2002) Multidrug resistance in cancer: Role of ATP-dependent transporters. Nat. Rev. Cancer, 2 48-58.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 2
    • 0035813012 scopus 로고    scopus 로고
    • Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters
    • Leslie, E.M., Deeley, R.G. and Cole, S.P. (2001) Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Toxicology, 167, 3-23.
    • (2001) Toxicology , vol.167 , pp. 3-23
    • Leslie, E.M.1    Deeley, R.G.2    Cole, S.P.3
  • 3
    • 0032744001 scopus 로고    scopus 로고
    • Structural, mechanistic and clinical aspects of MRP1
    • Hipfner, D.R., Deeley, R.G. and Cole, S.P. (1999) Structural, mechanistic and clinical aspects of MRP1. Biochim. Biophys. Acta, 1461, 359-376.
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 359-376
    • Hipfner, D.R.1    Deeley, R.G.2    Cole, S.P.3
  • 4
    • 3042848593 scopus 로고    scopus 로고
    • Pharmacogenetics of the Human MDR1 multidrug transporter
    • Lee, C.G.L., Chong, S.S. and Lee, E.J.D. (2004) Pharmacogenetics of the Human MDR1 multidrug transporter. Curr. Pharmacogenomics, 2, 1-11.
    • (2004) Curr. Pharmacogenomics , vol.2 , pp. 1-11
    • Lee, C.G.L.1    Chong, S.S.2    Lee, E.J.D.3
  • 6
    • 0035212059 scopus 로고    scopus 로고
    • Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution
    • Conrad, S., Kauffmann, H.M., Ito, K., Deeley, R.G., Cole, S.P. and Schrenk, D. (2001) Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution. J. Hum. Genet., 46, 656-663.
    • (2001) J. Hum. Genet. , vol.46 , pp. 656-663
    • Conrad, S.1    Kauffmann, H.M.2    Ito, K.3    Deeley, R.G.4    Cole, S.P.5    Schrenk, D.6
  • 7
    • 0035103009 scopus 로고    scopus 로고
    • Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
    • Ito, S., Ieiri, I., Tanabe, M., Suzuki, A., Higuchi, S. and Otsubo, K. (2001) Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/ cMOAT, in healthy Japanese subjects. Pharmacogenetics, 11, 175-184.
    • (2001) Pharmacogenetics , vol.11 , pp. 175-184
    • Ito, S.1    Ieiri, I.2    Tanabe, M.3    Suzuki, A.4    Higuchi, S.5    Otsubo, K.6
  • 8
    • 0036246271 scopus 로고    scopus 로고
    • Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR)
    • Saito, S., Iida, A., Sekine, A., Miura, Y., Ogawa, C., Kawauchi, S., Higuchi, S. and Nakamura, Y. (2002) Identification of 779 genetic variations in eight genes encoding members of the ATP-binding cassette, subfamily C (ABCC/MRP/CFTR). J. Hum. Genet., 47, 147-171.
    • (2002) J. Hum. Genet. , vol.47 , pp. 147-171
    • Saito, S.1    Iida, A.2    Sekine, A.3    Miura, Y.4    Ogawa, C.5    Kawauchi, S.6    Higuchi, S.7    Nakamura, Y.8
  • 9
    • 0035219750 scopus 로고    scopus 로고
    • Identification of novel polymorphisms in the pM5 and MRP1 (ABCC1) genes at locus l6p13.1 and exclusion of both genes as responsible for pseudoxanthoma elasticum
    • Perdu, J. and Germain, D.P. (2001) Identification of novel polymorphisms in the pM5 and MRP1 (ABCC1) genes at locus l6p13.1 and exclusion of both genes as responsible for pseudoxanthoma elasticum. Hum. Mutat., 17, 74-75.
    • (2001) Hum. Mutat. , vol.17 , pp. 74-75
    • Perdu, J.1    Germain, D.P.2
  • 11
    • 0041410061 scopus 로고    scopus 로고
    • Frequency of MRP1 genetic polymorphisms and their functional significance in Caucasians: Detection of a novel mutation G816A in the human MRP1 gene
    • Oselin, K., Mrozikiewicz, P.M., Gaikovitch, E., Pahkla, R. and Roots, I. (2003) Frequency of MRP1 genetic polymorphisms and their functional significance in Caucasians: Detection of a novel mutation G816A in the human MRP1 gene. Eur. J. Clin. Pharmacol., 59, 347-350.
    • (2003) Eur. J. Clin. Pharmacol. , vol.59 , pp. 347-350
    • Oselin, K.1    Mrozikiewicz, P.M.2    Gaikovitch, E.3    Pahkla, R.4    Roots, I.5
  • 12
  • 13
    • 0037307413 scopus 로고    scopus 로고
    • Signatures of natural selection in the human genome
    • Bamshad, M. and Wooding, S.P. (2003) Signatures of natural selection in the human genome. Nat. Rev. Genet., 4, 99-111.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 99-111
    • Bamshad, M.1    Wooding, S.P.2
  • 14
    • 5444236355 scopus 로고    scopus 로고
    • Positive selection on the human genome
    • Vallender, E.J. and Lahn, B.T. (2004) Positive selection on the human genome. Hum. Mol. Genet., 13, R245-R254.
    • (2004) Hum. Mol. Genet. , vol.13
    • Vallender, E.J.1    Lahn, B.T.2
  • 15
    • 0031875836 scopus 로고    scopus 로고
    • Glucose-6-phosphate dehydrogenase deficiency and malaria
    • Ruwende, C. and Hill, A. (1998) Glucose-6-phosphate dehydrogenase deficiency and malaria. J. Mol. Med., 76, 581-588.
    • (1998) J. Mol. Med. , vol.76 , pp. 581-588
    • Ruwende, C.1    Hill, A.2
  • 17
    • 1942421704 scopus 로고    scopus 로고
    • Genomic evidence for recent positive selection at the human MDR1 gene locus
    • Tang, K., Wong, L.P., Lee, E.J., Chong, S.S. and Lee, C.G. (2004) Genomic evidence for recent positive selection at the human MDR1 gene locus. Hum. Mol. Genet., 13, 783-797.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 783-797
    • Tang, K.1    Wong, L.P.2    Lee, E.J.3    Chong, S.S.4    Lee, C.G.5
  • 18
    • 1642523162 scopus 로고    scopus 로고
    • Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • Marzolini, C., Paus, E., Buclin, T. and Kim, R.B. (2004) Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance. Clin. Pharmacol. Ther., 75, 13-33.
    • (2004) Clin. Pharmacol. Ther. , vol.75 , pp. 13-33
    • Marzolini, C.1    Paus, E.2    Buclin, T.3    Kim, R.B.4
  • 19
    • 0036911353 scopus 로고    scopus 로고
    • Interrogating a high-density SNP map for signatures of natural selection
    • Akey, J.M., Zhang, G., Zhang, K., Jin, L. and Shriver, M.D. (2002) Interrogating a high-density SNP map for signatures of natural selection. Genome Res., 12, 1805-1814.
    • (2002) Genome Res. , vol.12 , pp. 1805-1814
    • Akey, J.M.1    Zhang, G.2    Zhang, K.3    Jin, L.4    Shriver, M.D.5
  • 21
    • 0036157464 scopus 로고    scopus 로고
    • Complex signatures of natural selection at the Duffy blood group locus
    • Hamblin, M.T., Thompson, E.E. and Di Rienzo, A. (2002) Complex signatures of natural selection at the Duffy blood group locus. Am. J. Hum. Genet., 70, 369-383.
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 369-383
    • Hamblin, M.T.1    Thompson, E.E.2    Di Rienzo, A.3
  • 22
    • 0033926130 scopus 로고    scopus 로고
    • Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations
    • Goddard, K.A., Hopkins, P.J., Hall, J.M. and Witte, J.S. (2000) Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. Am. J. Hum. Genet., 66, 216-234.
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 216-234
    • Goddard, K.A.1    Hopkins, P.J.2    Hall, J.M.3    Witte, J.S.4
  • 23
    • 0036667956 scopus 로고    scopus 로고
    • Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
    • Tang, K., Ngoi, S.M., Gwee, P.C., Chua, J.M.Z., Lee, E.J.D., Chong, S.C. and Lee, C.G.L. (2002) Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics, 12, 437-450.
    • (2002) Pharmacogenetics , vol.12 , pp. 437-450
    • Tang, K.1    Ngoi, S.M.2    Gwee, P.C.3    Chua, J.M.Z.4    Lee, E.J.D.5    Chong, S.C.6    Lee, C.G.L.7
  • 24
    • 0037390308 scopus 로고    scopus 로고
    • Linkage disequilibrium patterns of the human genome across populations
    • Shifman, S., Kuypers, J., Kokoris, M., Yakir, B. and Darvasi, A. (2003) Linkage disequilibrium patterns of the human genome across populations. Hum. Mol. Genet., 12, 771-776.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 771-776
    • Shifman, S.1    Kuypers, J.2    Kokoris, M.3    Yakir, B.4    Darvasi, A.5
  • 25
    • 0034977045 scopus 로고    scopus 로고
    • Linkage disequilibrium in humans: Models and data
    • Pritchard, J.K. and Przeworski, M. (2001) Linkage disequilibrium in humans: Models and data. Am. J. Hum. Genet., 69, 1-14.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1-14
    • Pritchard, J.K.1    Przeworski, M.2
  • 26
    • 0028106023 scopus 로고
    • Cloning and sequence analysis of the promoter region of the MRP gene of HL60 cells isolated for resistance to adriamycin
    • Zhu, Q. and Center, M.S. (1994) Cloning and sequence analysis of the promoter region of the MRP gene of HL60 cells isolated for resistance to adriamycin. Cancer Res., 54, 4488-4492.
    • (1994) Cancer Res. , vol.54 , pp. 4488-4492
    • Zhu, Q.1    Center, M.S.2
  • 27
    • 0036133044 scopus 로고    scopus 로고
    • AliBaba2: Context specific identification of transcription factor binding sites
    • Grabe, N. (2002) AliBaba2: Context specific identification of transcription factor binding sites. In Silico Biol., 2, S1-S15.
    • (2002) In Silico Biol. , vol.2
    • Grabe, N.1
  • 28
    • 0033915990 scopus 로고    scopus 로고
    • PatSearch: A pattern matcher software that finds functional elements in nucleotide and protein sequences and assesses their statistical significance
    • Pesole, G., Liuni, S. and D'Souza, M. (2000) PatSearch: A pattern matcher software that finds functional elements in nucleotide and protein sequences and assesses their statistical significance. Bioinformatics, 16, 439-450.
    • (2000) Bioinformatics , vol.16 , pp. 439-450
    • Pesole, G.1    Liuni, S.2    D'Souza, M.3
  • 29
    • 57549089243 scopus 로고    scopus 로고
    • Using TESS to predict transcription factor binding sites in DNA sequence
    • In Baxevanis, A.D. (ed.), John Wiley & Sons, Inc, USA
    • Schug, J. (2003) Using TESS to predict transcription factor binding sites in DNA sequence. In Baxevanis, A.D. (ed.), Current Protocols in Bioinformatics. John Wiley & Sons, Inc, USA, pp. 2.6.1-2.6.15.
    • (2003) Current Protocols in Bioinformatics
    • Schug, J.1
  • 30
    • 0022972654 scopus 로고
    • Internal duplication and homology with bacterial transport proteins in the mdrl (P-glycoprotein) gene from multidrug-resistant human cells
    • Chen, C.J., Chin, J.E., Ueda, K., Clark, D.P., Pastan, I., Gottesman, M.M. and Roninson, I.B. (1986) Internal duplication and homology with bacterial transport proteins in the mdrl (P-glycoprotein) gene from multidrug-resistant human cells. Cell, 47, 381-389.
    • (1986) Cell , vol.47 , pp. 381-389
    • Chen, C.J.1    Chin, J.E.2    Ueda, K.3    Clark, D.P.4    Pastan, I.5    Gottesman, M.M.6    Roninson, I.B.7
  • 34
    • 0033658948 scopus 로고    scopus 로고
    • Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium
    • Bonnen, P.E., Story, M.D., Ashorn, C.L., Buchholz, T.A., Weil, M.M. and Nelson, D.L. (2000) Haplotypes at ATM identify coding-sequence variation and indicate a region of extensive linkage disequilibrium. Am. J. Hum. Genet., 67, 1437-1451.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1437-1451
    • Bonnen, P.E.1    Story, M.D.2    Ashorn, C.L.3    Buchholz, T.A.4    Weil, M.M.5    Nelson, D.L.6
  • 36
    • 0037313361 scopus 로고    scopus 로고
    • Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: Findings from the family blood pressure program
    • Zhu, X., Yan, D., Cooper, R.S., Luke, A., Ikeda, M.A., Chang, Y.P., Weder, A. and Chakravarti, A. (2003) Linkage disequilibrium and haplotype diversity in the genes of the renin-angiotensin system: findings from the family blood pressure program. Genome Res., 13, 173-181.
    • (2003) Genome Res. , vol.13 , pp. 173-181
    • Zhu, X.1    Yan, D.2    Cooper, R.S.3    Luke, A.4    Ikeda, M.A.5    Chang, Y.P.6    Weder, A.7    Chakravarti, A.8
  • 38
    • 0028366089 scopus 로고
    • Repression of AP-1-stimulated transcription by c-Ets-1
    • Goldberg, Y., Treier, M., Ghysdael, J. and Bohmann, D. (1994) Repression of AP-1-stimulated transcription by c-Ets-1. J. Biol. Chem., 269, 16566-16573.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16566-16573
    • Goldberg, Y.1    Treier, M.2    Ghysdael, J.3    Bohmann, D.4
  • 39
    • 0034806474 scopus 로고    scopus 로고
    • Identification of DNA-protein interactions in the 5′ flanking and 5′ untranslated regions of the human multidrug resistance protein (MRP1) gene: Evaluation of a putative antioxidant response element/AP-1 binding site
    • Kurz, E.U., Cole, S.P. and Deeley, R.G. (2001) Identification of DNA-protein interactions in the 5′ flanking and 5′ untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site. Biochem. Biophys. Res. Commun., 285, 981-990.
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 981-990
    • Kurz, E.U.1    Cole, S.P.2    Deeley, R.G.3
  • 41
    • 0034063577 scopus 로고    scopus 로고
    • Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells
    • Sullivan, G.F., Yang, J.M., Vassil, A., Yang, J., Bash-Babula. J. and Hait, W.N. (2000) Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells. J. Clin. Invest. 105, 1261-1267.
    • (2000) J. Clin. Invest. , vol.105 , pp. 1261-1267
    • Sullivan, G.F.1    Yang, J.M.2    Vassil, A.3    Yang, J.4    Bash-Babula, J.5    Hait, W.N.6
  • 42
    • 0345304399 scopus 로고    scopus 로고
    • The power and promise of population genomics: From genotyping to genome typing
    • Luikart, G., England, P.R., Tallmon, D., Jordan, S. and Taberlet, P. (2003) The power and promise of population genomics: From genotyping to genome typing. Nat. Rev. Genet., 4, 981-994.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 981-994
    • Luikart, G.1    England, P.R.2    Tallmon, D.3    Jordan, S.4    Taberlet, P.5
  • 43
    • 0037381013 scopus 로고    scopus 로고
    • Simultaneous genotyping of seven single-nucleotide polymorphisms in the MDR1 gene by single-tube multiplex minisequencing
    • Gwee, P.C., Tang, K., Chua, J.M., Lee, E.J., Chong, S.S. and Lee, C.G. (2003) Simultaneous genotyping of seven single-nucleotide polymorphisms in the MDR1 gene by single-tube multiplex minisequencing. Clin. Chem. 49, 672-676.
    • (2003) Clin. Chem. , vol.49 , pp. 672-676
    • Gwee, P.C.1    Tang, K.2    Chua, J.M.3    Lee, E.J.4    Chong, S.S.5    Lee, C.G.6
  • 44
    • 0034057157 scopus 로고    scopus 로고
    • Effect of ABC transporters on HIV-1 infection: Inhibition of virus production by the MDR1 transporter
    • Lee, C.G., Ramachandra, M., Jeang, K.T., Martin, M.A., Pastan, I. and Gottesman, M.M. (2000) Effect of ABC transporters on HIV-1 infection: inhibition of virus production by the MDR1 transporter. FASEB J., 14, 516-522.
    • (2000) FASEB J. , vol.14 , pp. 516-522
    • Lee, C.G.1    Ramachandra, M.2    Jeang, K.T.3    Martin, M.A.4    Pastan, I.5    Gottesman, M.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.