Genetic polymorphisms of ATP-binding cassette transporters ABCB1 and ABCC2 and their impact on drug disposition

Current Drug Targets

Volumn 12, Issue 5, 2011, Pages 631-646

  Haufroid, Vincent ^a,b  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

Author keywords

ABCB1; ABCC2; Genotype; Intracellular concentrations; MDR1; MRP2; Pharmacogenomics; Polymorphism

Indexed keywords

ATAZANAVIR; CARBAMAZEPINE; CLOXACILLIN; CLOZAPINE; CYCLOSPORIN; DICLOXACILLIN; DIGOXIN; DOCETAXEL; DOXORUBICIN; EFAVIRENZ; FLUVOXAMINE; IMATINIB; INDINAVIR; LOPINAVIR; MULTIDRUG RESISTANCE PROTEIN 1; NELFINAVIR; NEVIRAPINE; PACLITAXEL; PHENOBARBITAL; PHENYTOIN; POSACONAZOLE; QUETIAPINE; RAPAMYCIN; RISPERIDONE; SAQUINAVIR; TACROLIMUS; UNINDEXED DRUG; VALACICLOVIR; VINCRISTINE; VORICONAZOLE;

ABCC2 GENE; AREA UNDER THE CURVE; CONGESTIVE HEART FAILURE; DRUG DISPOSITION; DRUG MEGADOSE; EXON; GENE; GENETIC POLYMORPHISM; GENOTYPE; GRAFT REJECTION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PHARMACOGENETICS; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

ATP-BINDING CASSETTE TRANSPORTERS; DRUG RESISTANCE, MULTIPLE; FEMALE; HUMANS; MALE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PHARMACEUTICAL PREPARATIONS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79953314999     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945011795378487     Document Type: Review

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