Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions

Science

Volumn 306, Issue 5704, 2004, Pages 2084-2087

  Kusch, Thomas ^a   Florens, Laurence ^a   MacDonald, W Hayes ^b   Swanson, Selene K ^a   Glaser, Robert L ^c   Yates III, John R ^b   Abmayr, Susan M ^a   Washburn, Michael P ^a   Workman, Jerry L ^a  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPLEXATION; DNA; ENZYME KINETICS; HORMONES; PHOSPHORESCENCE;

DNA DOUBLE-STRANDS; HISTONES; MULTIPROTEIN COMPLEX; PHOSPHORYLATION;

BIOCHEMISTRY;

DNA; DNA BINDING PROTEIN; HISTONE; PROTEIN TIP60; UNCLASSIFIED DRUG;

DNA; GENOME;

ACETYLATION; ARTICLE; CHROMATIN STRUCTURE; COMPLEX FORMATION; DNA REPAIR; DNA STRAND BREAKAGE; DROSOPHILA MELANOGASTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN PHOSPHORYLATION;

ACETYL COENZYME A; ACETYLATION; ACETYLTRANSFERASES; ADENOSINE TRIPHOSPHATASES; ANIMALS; CELL LINE; DIMERIZATION; DNA DAMAGE; DNA REPAIR; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; HISTONE ACETYLTRANSFERASES; HISTONES; MULTIPROTEIN COMPLEXES; NUCLEOSOMES; PHOSPHORYLATION; RECOMBINANT PROTEINS; RNA INTERFERENCE; TRANSCRIPTION FACTORS;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 10844233155     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1103455     Document Type: Article

References (30)

1. O. Fernandez-Capetillo, A. Celeste, A. Nussenzweig, Cell Cycle 2, 426 (2003).
2. C. Bernstein, H. Bernstein, C. M. Payne, H. Garewal, Mutat. Res. 511, 145 (2002).
3. G. Langst, P. B. Becker, Biochim. Biophys. Acta 1677, S8 (2004).
4. A. Lusser, J. T. Kadonaga, Bioessays 25, 1192 (2003).
5. T. Jenuwein, C. D. Allis, Science 293, 1074 (2001).
6. Y. Wang et al., Novartis Found. Symp. 259, 3 (2004).
7. H. S. Malik, S. Henikoff, Nat. Struct. Biol. 10, 882 (2003).
8. K. Ahmad, S. Henikoff, Mol. Cell 9, 1191 (2002).
9. G. Mizuguchi et al., Science 303, 343 (2004); published online 26 November 2003 (10.1126/science.1090701).
10. M. S. Kobor et al., PLoS Biol. 2, E131 (2004).
11. N. J. Krogan et al., Mol. Cell 12, 1565 (2003).
12. C. Redon et al., Curr. Opin. Genet. Dev. 12, 162 (2002).
13. H. Scherthan, Cytogenet. Genome Res. 103, 235 (2003).
14. C. Redon et al., EMBO Rep. 4, 678 (2003).
15. J. P. Madigan, H. L. Chotkowski, R. L. Glaser, Nucleic Acids Res. 30, 3698 (2002).
16. S. Allard, J. Y. Masson, J. Cote, Biochim. Biophys. Acta 1677, 158 (2004).
17. T. Ikura et al., Cell 102, 463 (2000).
18. Materials and methods are available as supporting material on Science Online.
19. T. Kusch, S. Guelman, S. M. Abmayr, J. L. Workman, Mol. Cell. Biol. 23, 3305 (2003).
20. T. Kusch et al., unpublished data.
21. J. A. Downs, N. F. Lowndes, S. P. Jackson, Nature 408, 1001 (2000).
22. Y. Cai et al., J. Biol. Chem. 278, 42733 (2003).
23. Y. Doyon, W. Selleck, W. S. Lane, S. Tan, J. Cote, Mol. Cell. Biol. 24, 1884 (2004).
24. A. W. Bird et al., Nature 419, 411 (2002).
25. J. S. Choy, S. J. Kron, Mol. Cell Biol. 23, 8215 (2002).
26. Y. Doyon, J. Cote, Curr. Opin. Genet. Dev. 14, 147 (2004).
27. K. Halkidou et al., Oncogene 22, 2466 (2003).
28. N. Motoyama, K. Naka, Curr. Opin. Genet. Dev. 14, 11 (2004).
29. O. A. Sedelnikova, D. R. Pilch, C. Redon, W. M. Bonner, Cancer Biol. Ther. 2, 233 (2003).
30. We thank the Bloomington Stock Center and C. Wu, J. Kadonaga, M.-L. Ruhf, and M. Meister for providing reagents. We are indebted to the Stowers core facilities for their support. Special thanks to N. Bae, K. Lee, and K. Trujillo for insightful comments on the manuscript.